CN105496611A - Porous implant filled with O-intersecting lines units - Google Patents

Porous implant filled with O-intersecting lines units Download PDF

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Publication number
CN105496611A
CN105496611A CN201510946486.2A CN201510946486A CN105496611A CN 105496611 A CN105496611 A CN 105496611A CN 201510946486 A CN201510946486 A CN 201510946486A CN 105496611 A CN105496611 A CN 105496611A
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porous
intersectinglines
unit
implant
filled
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Inventor
张春雨
孙学通
陈贤帅
林志生
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Guangzhou Institute of Advanced Technology of CAS
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Guangzhou Institute of Advanced Technology of CAS
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Priority to CN201510946486.2A priority Critical patent/CN105496611A/en
Publication of CN105496611A publication Critical patent/CN105496611A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/32Joints for the hip
    • A61F2/36Femoral heads ; Femoral endoprostheses
    • A61F2/3609Femoral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic femoral shafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30942Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/04Metals or alloys
    • A61L27/06Titanium or titanium alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2825Femur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30621Features concerning the anatomical functioning or articulation of the prosthetic joint
    • A61F2002/30622Implant for fusing a joint or bone material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30942Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30943Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using mathematical models
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30985Designing or manufacturing processes using three dimensional printing [3DP]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Prostheses (AREA)
  • Geometry (AREA)
  • Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)

Abstract

A porous implant filled with O-intersecting lines units is mainly oriented to femoral stems and comprises a femoral stem end, a porous main body part and a screw positioning hole part, wherein the femoral stem end is used for positioning the porous implant, the screw positioning hole part is used for fixing the implant and a host, the porous main body part is a three-dimensional through porous network entity mainly formed by being filled with the O-intersecting lines units, the porous network entity comprises hollowed-out entities formed by scanning of O-intersecting lines unit cylinders penetrating through and crossing with one another in space, the hollowed-out entities are formed by pairwise perpendicular and linearly stacked O-intersecting lines unit cylinder surfaces, and the porous network entity has the pore diameter ranging from 400 mu m to 1,000 mu m, the unit wall thickness ranging from 80 mu m to 120 mu m and the porosity ranging from 55% to 85%. Thus, a porous network structure formed by stacking of the hollowed-out entities is close to a bone structure, has the high porosity, the high communication ratio and the larger surface contact area, is suitable for new bone ingrowth and circulation of nutrition tissue liquids and has the considerable clinical medical prospect.

Description

A kind of porous implant of being filled by O-intersecting lines unit
Technical field
Category belonging to the present invention is biological medical instruments field, relates to a kind of porous implant, is specifically related to a kind of porous implant of being filled by O-intersectinglines (column intersection line) unit.
Background technology
Long bone the longest in human body is femur, and it can divide and is integrated two ends, and similar bone is as humerus etc.Femur is also known as Thigh bone, and it is mainly used in the trunk, pelvis etc. of support human body, and be maximum bone that bears a heavy burden, be all extremely important in numerous animals such as the mankind.
But, the disease bad due to some or wound etc. cause femur to rupture and cause large-area Cranial defect, and when cannot be healed by autologous tissue, then need to consider bone collection, particularly for some old peoples, best Therapeutic Method is exactly artificial bone or replacement joint, can avoid the situation of postoperative generation Avascular Necrosis Of Femur Head like this.Femur supports and maximum skeletal structure that bears a heavy burden as in human body, must be paid attention to.
The technology of current existing a lot of bone collection.Use solid metal bone collection traditionally, although cost is low, but implant deadweight is excessive, patient can be made not feel well, and it can cause obvious stress capture-effect, this stimulation that will primary bone tissue caused well can not to be subject to external force, cause it to soften, moreover, also because solid metal implant fails to provide enough space for inducing the regrowth of original structure, primary bone tissue finally may be caused to come off, and therefore this technology not can solve Cranial defect problem; There is degradable biomaterial in addition as the graft technology of bone implant, this degradable biomaterial can adapt to the primary structure of host, obvious rejection can not be produced, but, its intensity is not enough unavoidably, and as the implant of femur structure, based on the heavy burden effect of femur, need implant to have enough intensity, therefore this employing degradable biomaterial neither optimum selection as bone implant.
Tradition is main still based on certain algorithm and image processing techniques for the bone trabecular method for designing of porous, by gathering human bone microstructure image, extract peripheral outline, the data obtained are carried out interpolation and are repaired generating vector diagram, finally each layer data are carried out summation and obtain three-dimensional porous structure.There is closed cell in this design, and closed cell will be not suitable for the regeneration of osseous tissue and grow into unavoidably, because for femur model, ensure that the connection between bone trabecula is very important, in addition, this mode is difficult to the unified unit of create-rule, is therefore difficult to ensure stressed uniformity.
Summary of the invention
In view of this, the present invention is intended to propose Improving ways in the shortcoming of traditional bone implant and the difficulty of bone trabecula design, it is mainly by a kind of porous implant of being filled by O-intersectinglines unit of design, and carry out Design and manufacture for femur model, in order to realize Simple Design and the manufacture of bone implant, finally for femur implanted prosthetics provides good medical reference to be worth.
The present invention is solved the problem by following technological means:
A kind of porous implant of being filled by O-intersectinglines unit, it is mainly towards femoral stem, comprise femur pommel, porous bodies part and screw pilot hole position, described femur pommel is for locating described porous implant, described screw pilot hole position is used for fixing implant and host, the through porous network entity of three-dimensional that described porous bodies part is filled primarily of O-intersectinglines unit, described porous network entity be by O-intersectinglines unit cylinder to pass through mutually in space intersect the hollow out entity that scans, the aperture of described porous network entity is 400-1000 μm, unit wall thickness is 80-120 μm, porosity is 55%-85%.
Further, described hollow out entity forms by the O-intersectinglines unit face of cylinder is orthogonal, linearly stacking between two in space.
Further, described porous implant is made primarily of human implantable metal material, preferred pure titanium metal, titanium alloy, rustless steel and vitallium.
Further, described O-intersectinglines unit form is that second order cylinder passes through cellular construction mutually or three rank cylinders pass through cellular construction mutually.
Preferably, when described O-intersectinglines unit form is second order cylinder units, described perforated grill entity aperture is 500 μm, pipeline wall thickness is 100 μm, porosity is 72%; When described O-intersectinglines unit form is three rank cylinder units, described perforated grill entity aperture is 500 μm, pipeline wall thickness is 100 μm, porosity is 69%.
Preferably, described femur pommel, described porous bodies part and described screw pilot hole position are linked to be an entirety, do not need to assemble direct disposal molding in addition.
The preparation method of porous implant of the present invention comprises the following steps:
S1. Three-dimensional Design Software is utilized to draw the threedimensional model of O-intersectinglines unit on computers, the threedimensional model face of cylinder is orthogonal between two in space, linearly stacking, by given its aperture of concrete size Control, wall thickness and porosity, generation unit structure cell entity;
S2. array processing is copied to unit structure cell entity, obtain space porous network entity;
S3. the femur three-dimensional surface model that reverse-engineering obtains is directed through, to scaling of model to the ratio of actual needs;
S4. cutting is carried out to porous network entity and femur three-dimension curved surface and Boolean calculation operates, obtain porous bodies part;
S5. draw femur pommel and screw pilot hole position by three-dimensional modeling, and merge porous bodies part and make it to become single output porous implant entity;
S6. porous implant entity preserved into output format file and transfer in delamination software, adding bottom supporting;
S7. open fiber selectivity laser fusion equipment metal material 3D printer, porous implant entity is printed;
S8. clear up substrate, take out with the porous implant that 3D prints by shovel file;
S9. blasting treatment is carried out to porous implant, make its any surface finish;
S10. porous implant is encapsulated.
Preferably, in step S1, described Three-dimensional Design Software is solidworks or pro-eUG.
Preferably, in step S6, described output format file is stl, and described delamination software is ontofab.
Preferably, in step S7, described fiber selectivity laser fusion equipment metal material 3D printer model is SLM125HL.
Further, in step S7, described print parameters is set as: pure titanium density is 4.55g/cm3, laser spot diameter d=80-85 μm, sweep span h=100-200 μm, power P=70-100W, scan velocity V=100-500mm/s, paving powder thickness t=40-70 μm.
The invention provides porous implant of being filled by O-intersectinglines unit and preparation method thereof, compared with prior art, thus hollow out entity stacking porous network structure close to bone structure, there is high porosity, high connected ratio and larger contact surface area, applicable area of new bone is grown into and the circulation of nutritive issue liquid, loose structure and pure titanium material provide enough high strength also to avoid too many stress shielding, highly interconnected through hole structure can provide Bone Ingrowth widely, the initial stability that ideal material makes coefficient of friction provide good, possess the potentiality of good implant, there is considerable clinical medical prospect, the preparation method of porous implant is more reliably feasible, is convenient to adopt 3D to print and processes.
Accompanying drawing explanation
Fig. 1 is second order O-intersectinglines cell schematics;
Fig. 2 is three rank O-intersectinglines cell schematics;
Fig. 3 is second order O-intersectinglines element stack schematic diagram;
Fig. 4 is three rank O-intersectinglines element stack schematic diagrams;
Fig. 5 is the porous implant schematic diagram of being filled by O-intersectinglines unit.
Detailed description of the invention
For enabling above-mentioned purpose of the present invention, feature and advantage become apparent more, are described in detail to technical scheme of the present invention below in conjunction with accompanying drawing and specific embodiment.
Please refer to Fig. 1, Fig. 3 and Fig. 5, a kind of porous implant of being filled by O-intersectinglines unit, it is mainly towards femoral stem, comprise femur pommel, porous bodies part and screw pilot hole position, described femur pommel is for locating described porous implant, described screw pilot hole position is used for fixing implant and host, the through porous network entity of three-dimensional that described porous bodies part is filled primarily of O-intersectinglines unit, described O-intersectinglines unit form is that second order cylinder passes through cellular construction mutually, described porous network entity be by O-intersectinglines unit cylinder to pass through mutually in space intersect the hollow out entity that scans, described hollow out entity is orthogonal between two in space by the O-intersectinglines unit face of cylinder, linearly stackingly to form, described perforated grill entity aperture is 500 μm, pipeline wall thickness is 100 μm, porosity is 72%, described porous implant is made primarily of human implantable metal material, preferred pure titanium metal, titanium alloy, rustless steel and vitallium, described femur pommel, described porous bodies part and described screw pilot hole position are linked to be an entirety, do not need to assemble direct disposal molding in addition.
Please refer to Fig. 2, Fig. 4 and Fig. 5, a kind of porous implant of being filled by O-intersectinglines unit, it is mainly towards femoral stem, comprise femur pommel, porous bodies part and screw pilot hole position, described femur pommel is for locating described porous implant, described screw pilot hole position is used for fixing implant and host, the through porous network entity of three-dimensional that described porous bodies part is filled primarily of O-intersectinglines unit, described O-intersectinglines unit form is that three rank cylinders pass through cellular construction mutually, described porous network entity be by O-intersectinglines unit cylinder to pass through mutually in space intersect the hollow out entity that scans, described hollow out entity is orthogonal between two in space by the O-intersectinglines unit face of cylinder, linearly stackingly to form, described perforated grill entity aperture is 500 μm, pipeline wall thickness is 100 μm, porosity is 69%, described porous implant is made primarily of human implantable metal material, preferred pure titanium metal, titanium alloy, rustless steel and vitallium, described femur pommel, described porous bodies part and described screw pilot hole position are linked to be an entirety, do not need to assemble direct disposal molding in addition.
The preparation method of porous implant of the present invention comprises the following steps:
S1. Three-dimensional Design Software is utilized to draw the threedimensional model of O-intersectinglines unit on computers, the threedimensional model face of cylinder is orthogonal between two in space, linearly stacking, by given its aperture of concrete size Control, wall thickness and porosity, generation unit structure cell entity;
Specific as follows: to use solidworks Three-dimensional Design Software on computers, draw O-intersectinglines second order or three rank column intersection line space lattice unit, dimensioning makes that pore size is 500 μm, wall thickness size is 100 μm, porosity is 65%-75%;
S2. array processing is copied to unit structure cell entity, obtain space porous network entity;
S3. the femur three-dimensional surface model that reverse-engineering obtains is directed through, to scaling of model to the ratio of actual needs;
S4. cutting is carried out to porous network entity and femur three-dimension curved surface and Boolean calculation operates, obtain porous bodies part;
S5. draw femur pommel and screw pilot hole position by three-dimensional modeling, and merge porous bodies part and make it to become single output porous implant entity;
S6. porous implant entity preserved into output format file and transfer in delamination software, adding bottom supporting;
Wherein, output format file stl, delamination software is ontofab;
S7. open fiber selectivity laser fusion equipment metal material 3D printer, porous implant entity is printed;
Specific as follows: to open SLM125HL fiber selectivity laser fusion equipment metal material 3D printer, print porous implant, wherein print parameters is set to: pure titanium density is 4.55g/cm3, laser spot diameter d=83 μm, sweep span h=100-200 μm, power P=70-100W, scan velocity V=100-500mm/s, paving powder thickness t=30-70 μm;
S8. clear up substrate, take out with the porous implant that 3D prints by shovel file;
S9. blasting treatment is carried out to porous implant, make its any surface finish;
S10. porous implant is encapsulated.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (6)

1. a porous implant of being filled by O-intersectinglines unit, it is mainly towards femoral stem, it is characterized in that, comprise femur pommel, porous bodies part and screw pilot hole position, described femur pommel is for locating described porous implant, described screw pilot hole position is used for fixing implant and host, the through porous network entity of three-dimensional that described porous bodies part is filled primarily of O-intersectinglines unit, described porous network entity be by O-intersectinglines unit cylinder to pass through mutually in space intersect the hollow out entity that scans, the aperture of described porous network entity is 400-1000 μm, unit wall thickness is 80-120 μm, porosity is 55%-85%.
2. porous implant of being filled by O-intersectinglines unit according to claim 1, is characterized in that, described hollow out entity forms by the O-intersectinglines unit face of cylinder is orthogonal, linearly stacking between two in space.
3. porous implant of being filled by O-intersectinglines unit according to claim 2, it is characterized in that, described porous implant is made primarily of human implantable metal material, and described metal material comprises pure titanium metal, titanium alloy, rustless steel and vitallium.
4. the porous implant of by O-intersectinglines unit being filled described arbitrarily according to claim 1-3, it is characterized in that, described O-intersectinglines unit form is that second order cylinder passes through cellular construction mutually or three rank cylinders pass through cellular construction mutually.
5. porous implant of being filled by O-intersectinglines unit according to claim 4, it is characterized in that, when described O-intersectinglines unit form is second order cylinder units, described perforated grill entity aperture is 500 μm, pipeline wall thickness is 100 μm, porosity is 72%; When described O-intersectinglines unit form is three rank cylinder units, described perforated grill entity aperture is 500 μm, pipeline wall thickness is 100 μm, porosity is 69%.
6. porous implant of being filled by O-intersectinglines unit according to claim 5, it is characterized in that, described femur pommel, described porous bodies part and described screw pilot hole position are linked to be an entirety, do not need to assemble direct disposal molding in addition.
CN201510946486.2A 2015-12-15 2015-12-15 Porous implant filled with O-intersecting lines units Pending CN105496611A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
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CN106109064A (en) * 2016-06-15 2016-11-16 东北大学 A kind of spinal fusion device
CN106236328A (en) * 2016-08-29 2016-12-21 中奥汇成科技股份有限公司 A kind of novel porous titanium artificial hip joint
CN108125735A (en) * 2017-12-25 2018-06-08 北京爱康宜诚医疗器材有限公司 Type femoral bone end prosthesis
CN108256206A (en) * 2018-01-06 2018-07-06 石家庄铁道大学 A kind of complex network modeling method of engraved structure product model
CN111297519A (en) * 2020-02-17 2020-06-19 赵德伟 Metal hip joint prosthesis with porous layer structure and preparation method thereof
CN111728741A (en) * 2020-07-06 2020-10-02 吉林大学 Human body personalized hip joint femoral stem prosthesis adopting lightweight design and manufacturing method thereof
CN113456310A (en) * 2021-06-17 2021-10-01 嘉思特华剑医疗器材(天津)有限公司 Bionic minimally invasive hip joint femoral stem prosthesis with femoral neck remaining function
CN115887069A (en) * 2023-02-15 2023-04-04 吉林大学 Femoral shaft multilayer composite bionic self-fixing prosthesis

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6206924B1 (en) * 1999-10-20 2001-03-27 Interpore Cross Internat Three-dimensional geometric bio-compatible porous engineered structure for use as a bone mass replacement or fusion augmentation device
CN201164513Y (en) * 2008-03-03 2008-12-17 曼德卡姆有限公司 Artificial hip joint and femur shaft
CN201394098Y (en) * 2009-06-01 2010-02-03 北京爱康宜诚医疗器材有限公司 Artificial hip joint fused femoral stem
US20110014081A1 (en) * 2004-12-30 2011-01-20 Howmedica Osteonics Corp. Laser-produced porous structure
CN102548509A (en) * 2009-08-19 2012-07-04 史密夫和内修有限公司 Porous implant structures
CN203154006U (en) * 2013-04-01 2013-08-28 重庆润泽医药有限公司 Anti-loosening type artificial hip joint
US20130268085A1 (en) * 2012-04-06 2013-10-10 The University Of Liverpool Surface modified unit cell lattice structures for optimized secure freeform fabrication
CN203291079U (en) * 2013-06-13 2013-11-20 重庆润泽医药有限公司 Hip joint femoral stem replacement
CN104646669A (en) * 2013-11-25 2015-05-27 广州中国科学院先进技术研究所 Biomedical porous pure-titanium implant material and preparation method thereof
CN104784760A (en) * 2015-03-25 2015-07-22 华南协同创新研究院 Low-elastic-modulus integrated titanium-based femoral handle and preparation method thereof

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6206924B1 (en) * 1999-10-20 2001-03-27 Interpore Cross Internat Three-dimensional geometric bio-compatible porous engineered structure for use as a bone mass replacement or fusion augmentation device
US20110014081A1 (en) * 2004-12-30 2011-01-20 Howmedica Osteonics Corp. Laser-produced porous structure
CN201164513Y (en) * 2008-03-03 2008-12-17 曼德卡姆有限公司 Artificial hip joint and femur shaft
CN201394098Y (en) * 2009-06-01 2010-02-03 北京爱康宜诚医疗器材有限公司 Artificial hip joint fused femoral stem
CN102548509A (en) * 2009-08-19 2012-07-04 史密夫和内修有限公司 Porous implant structures
US20130268085A1 (en) * 2012-04-06 2013-10-10 The University Of Liverpool Surface modified unit cell lattice structures for optimized secure freeform fabrication
CN203154006U (en) * 2013-04-01 2013-08-28 重庆润泽医药有限公司 Anti-loosening type artificial hip joint
CN203291079U (en) * 2013-06-13 2013-11-20 重庆润泽医药有限公司 Hip joint femoral stem replacement
CN104646669A (en) * 2013-11-25 2015-05-27 广州中国科学院先进技术研究所 Biomedical porous pure-titanium implant material and preparation method thereof
CN104784760A (en) * 2015-03-25 2015-07-22 华南协同创新研究院 Low-elastic-modulus integrated titanium-based femoral handle and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
肖冬明: "面向植入体的多孔结构建模及激光选区熔化直接制造研究", 《中国博士学位论文全文数据库 工程科技I辑》 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109064A (en) * 2016-06-15 2016-11-16 东北大学 A kind of spinal fusion device
CN106236328A (en) * 2016-08-29 2016-12-21 中奥汇成科技股份有限公司 A kind of novel porous titanium artificial hip joint
CN108125735A (en) * 2017-12-25 2018-06-08 北京爱康宜诚医疗器材有限公司 Type femoral bone end prosthesis
CN108256206A (en) * 2018-01-06 2018-07-06 石家庄铁道大学 A kind of complex network modeling method of engraved structure product model
CN111297519A (en) * 2020-02-17 2020-06-19 赵德伟 Metal hip joint prosthesis with porous layer structure and preparation method thereof
CN111728741A (en) * 2020-07-06 2020-10-02 吉林大学 Human body personalized hip joint femoral stem prosthesis adopting lightweight design and manufacturing method thereof
CN113456310A (en) * 2021-06-17 2021-10-01 嘉思特华剑医疗器材(天津)有限公司 Bionic minimally invasive hip joint femoral stem prosthesis with femoral neck remaining function
CN115887069A (en) * 2023-02-15 2023-04-04 吉林大学 Femoral shaft multilayer composite bionic self-fixing prosthesis

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