CN105708584A - Integral bionic cervical disc prosthesis - Google Patents
Integral bionic cervical disc prosthesis Download PDFInfo
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- CN105708584A CN105708584A CN201610031666.2A CN201610031666A CN105708584A CN 105708584 A CN105708584 A CN 105708584A CN 201610031666 A CN201610031666 A CN 201610031666A CN 105708584 A CN105708584 A CN 105708584A
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- elastomer
- rigid endplate
- artificial disc
- lower rigid
- cervical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
Abstract
The invention relates to an integral bionic cervical disc prosthesis, and belongs to the field of medicalimplant materials. The cervical disc prosthesis consists of an upper rigid terminal plate, a lower rigid terminal plate, an elastic body nucleus pulposus material and an outer layer protection film material, wherein the elastic body nucleus pulposus material is used for connecting the upper and lower rigid terminal plates; the elastic body material and the upper and lower rigid terminal plates are integrally formed in situ; through the structure arrangement of rigid terminal plate cavities, grooves, bulges and the like, the firm combination of the nucleus pulposus material and the rigid terminal plates is realized; a mutually embedding and covering integral structure is formed; and potential danger of material damage and abrasive dust caused by interface friction of the rigid terminal plates and the nucleus pulposus material is effectively reduced or eliminated. The surfaces, in contact with the bone of the human body, of upper and lower rigid terminal plates adopt the arc-shaped design; titanium or hydroxylapatite coatings cover the surfaces; spurs or sawtooth-shaped fixed teeth are distributed on the surface; and the immediate post-surgical stability and the bone integration are improved. The cervical disc prosthesis can realize the rotating, bending-stretching and transverse moving three-dimensional six-freedom-degree space movement; and the normal intervertebral disc moving functions in the human body can be met.
Description
Technical field
The present invention relates to a kind of novel artificial cervical intervertebral disk prosthesis, for replacing the intervertebral disc of regression between spinal column adjacent vertebrae, belong to medical embedded property orthopedic medical device field.
Background technology
Cervical spondylosis is a kind of commonly encountered diseases and frequently-occurring disease, and along with the quickening of modern life rhythm, living-pattern preservation (as take a bus instead of walking, sitting motionless), the sickness rate of whole world cervical intervertebral disk disease rises year by year.The treatment of cervical intervertebral disk disease includes the therapeutic modalities such as conservative and operation, and for disc disease that is serious and that quickly grow, operative treatment is therapeutic modality best at present.Existing therapeutic modality has allogeneic intercalated disc to transplant, replacement disc nucleus, merges decompression bone graft fusion, and cervical artificial disc replaces four kinds.Operative treatment that first three is comparatively traditional or there is rule of origin difficulty or there is rejection or there is the defects such as cervical vertebra adjacent segment LOM, full cervical artificial disc replacement is just in view of the defect of traditional therapy is arisen at the historic moment, after its design concept Shi Qian road discectomy by intervertebral space implant one can be movable device, replace original intervertebral disc and exercise its function, realize retaining the motor function of cervical vertebra motion, there is provided the stability required for cervical vertebra, it is prevented that with the purpose of the generation and development that delay adjacent phases regression simultaneously.
Existing more than ten kind cervical intervertebral disk prosthesis list or enter clinical stage through FDA approval in the world at present, and at home, there is no the cervical intervertebral disk prosthesis launch of independent research.The cervical intervertebral disk prosthesis of application can be divided into two classes at present; one class is the rigidity intercalated disc at single movement center; though this type of prosthese can keep the mobility of cervical vertebra substantially; but not there is elasticity; cervical vertebra can not be well protected when being subject to shaking; additionally metal and intermetallic abrasive dust, can impact the tissue of surrounding.Another kind of is the center of doing more physical exercises, the intercalated disc being vertebral pulp with macromolecular material, intervertebral disk prosthesis as disclosed in patent CN102648879A, CN101961270A, CN103417313A etc., adopt superhigh molecular weight polyethylene material or polyether-ether-ketone as nucleus material, but its structure still belongs to and firmly supports socket arrangement, this hard support mechanical characteristic differs relatively big with the perfect structure of human cervical spine intercalated disc and mechanics sex character, and still suffers from certain abrasive dust hidden danger.Actually, human cervical spine intercalated disc is between cervical vertebra two vertebral body, the seal being made up of cartilaginous lamina, fibrous ring, vertebral pulp, its nucleus material is a kind of limber colloid substance, when being subject to external force, stress is sent to each several part of fibrous ring by vertebral pulp by changing form, and the tensile stress then through fibrous ring is disperseed, thus playing the effect absorbing and transmitting outer forced oscillation.Human cervical spine intercalated disc is substantially that one has elastic structure, it is clear that traditional hard sliding friction structure supported can not well simulate structure and the activity characteristic of human cervical spine intercalated disc.In recent years, the research about the intervertebral disk prosthesis being vertebral pulp with elastomeric material started to cause the concern of people, the artificial intervertebral disk of this kind of elastomer class, it is possible to absorbs the impact in vertical, and has the ability bearing load, has better bionical effect.The difficult point of this type of artificial intervertebral disk is in that how realizing elastomer nucleus material is connected with the fixing of rigid endplate, traditional by connected modes such as mechanical interlock, although achieving certain connection, but elastomer nucleus material and metal rigidity soleplate meeting Presence of an interface problem, still suffer from problems such as making material abrasion, raw heat because repeatedly rubbing, come off in the long-time use procedure that implants.Two kinds of all-in-one-piece artificial intervertebral disks disclosed in patent CN101836907A and patent 292927749U, connected by integral type, reduce the frictional interface of elastomer and rigid endplate material to a certain extent, but its overall structure is mainly formed by follow-up assembling of rigid endplate, elastic vertebral pulp and other associated components, and elastomeric core and rigid endplate still suffer from interface.Additionally, due to rigid endplate and elastic intramarrow nuclear material, the DEFORMATION RESPONSE of load there is is larger difference, in life-time service process, also can produce new interface between rigid endplate and elastomer nucleus material.In implanting human body long time running process, still having some Interface Problems between rigid endplate and elastomer vertebral pulp, the fastness of the assembling of each parts and stability also have certain impact.Additionally, major part cervical artificial disc is for preventing from because intercalated disc mobility is excessive, intercalated disc periarticular tissue being damaged at present, adopt some position limiting structures in design, but these structures mostly are rigid structure, after cervical artificial disc reaches certain mobility, under the effect of rigid limit structure, activeness can stop suddenly, the process that neither one transition is spacing, it is impossible to simulate the function of human intervertebral disc well.Based on the defect of the trend of current cervical spondylosis and relevant cervical artificial disc product, the cervical artificial disc more bionical for exploitation performance has lasting demand.
Summary of the invention
For the problems referred to above of existing cervical artificial disc, the invention provides a kind of more bionical integral type cervical artificial disc prosthese.Described cervical artificial disc prosthese, by upper and lower rigid endplate, connects elastomer nucleus material and the outer layer protection membrane material composition of upper and lower rigid endplate.Described cervical artificial disc prosthese has following distinguishing feature: (1) elastomer nucleus material passes through the method for formed in situ with upper, lower rigid endplate integration formed in situ, and by the cavity of upper and lower rigid endplate, groove, boss, the structures such as through hole, form the integral structure of rigid endplate and the mutual chimeric cladding of elastomer nucleus material, it is absent from the articular surface of elastomer vertebral pulp and rigid endplate, overcome the rigid endplate of current artificial intervertebral disk and the frictional interface problem of polymeric material, effectively reduce or eliminate material damage and abrasive dust hidden danger that rigid endplate and nucleus material cause because of interface friction；(2) design flexible body position limiting structure between rigid endplate up and down, after cervical artificial disc reaches certain mobility, it is realized elastic spacing, be prevented effectively from because of the damage of the excessive adjacent joints caused of cervical artificial disc mobility；(3) the elastic non-hard support slide construction of whole cervical artificial disc, effectively realizes cervical artificial disc in the activity rotating, bend and stretch, translate three-dimensional six-freedom degree space by the elastic deformation of elastomer nucleus material；(4) surface that upper and lower rigid endplate contacts with vertebra adopts the radian design approximate with vertebral surface, there is after implantation higher contact surface with vertebra, in operation can the bone soleplate of reservation human vertebrae as much as possible, simplify the operation of operation, and retain overhauling property；(5) design of rigid endplate surface has stable tooth and titanium coating or hydroxyapatite coating layer structure, effectively realizes the Initial stability of cervical artificial disc and the Integrated implant in later stage after implantation；(6) outside nucleus material, design has one layer of elastic protective film, it is possible to grow into effectively preventing human body soft tissue.
The integrated formed in situ of described elastomer nucleus material and upper and lower soleplate, is first insert between upper and lower rigid endplate by elastomer or elastomer presoma, by the curing cross-linking reaction of elastomer or elastomer presoma, closely affixed with upper and lower rigid endplate.Before elastomer nucleus material molding used, there is good mobility, can be full of in upper and lower rigid endplate in the structures such as the cavity of setting, groove, hole, form the integral structure of elastomer-rigid endplate chimeric cladding mutually.In the activity of cervical artificial disc, it is absent from the frictional interface of rigid endplate and elastomer vertebral pulp, it is possible to effectively reduce effect and reduce or eliminate material damage and the abrasive dust hidden danger that rigid endplate and nucleus material cause because of interface friction.
After described elastomer nucleus material molding, there is higher intensity (more than 20MPa), it is possible to meet the condition of long bearing load；There is higher elastic deformation (more than 200%), it is possible to by the deformation of elastomer self effectively simulation human cervical spine intercalated disc in the activeness rotating, bend and stretch, translate three-dimensional six-freedom degree space；Compression set (GB/T7759-1996) relatively low (less than 10%), it is ensured that after long-time implantation human body, cervical artificial disc does not have obvious height change, is prevented effectively from intervertebral.
In described upper and lower rigid endplate, the cross section of the side contacted with vertebra is for consistent with vertebra shape of cross section；The side contacted with elastomer nucleus material, containing a cavity, the cross section of rigid endplate is circular or oval.A central boss (1c is contained at the center of upper and lower rigid endplate cavity, 2c), the height of central boss is 1～2.5mm, central boss is cylindric, being divided into two-layer from rigid endplate to elastomer nucleus material direction, the boss radius near elastomer nucleus material center is more than the boss radius near rigid endplate.Containing porose, groove structure in central boss, containing fluted (1d on the inner surface of upper and lower rigid endplate cavity, 2d) structure and bulge-structure (1e, 2e), these groove structures and bulge-structure or be uniformly distributed in rigid endplate inner surface with discontinuous form, or it is distributed in rigid endplate inner surface with continuous print concentric annular.The design of this structure, adds the contact area of elastomer nucleus material and rigid endplate, after elastomer vertebral pulp formed in situ integrated with rigid endplate, it is possible to achieve elastomer nucleus material is more firmly combined with rigid endplate.In the outside of the cavity of upper and lower rigid endplate, distribution has 4～8 through holes being similar to hole 1f and hole 2f respectively, and near the side of elastomer vertebral pulp in upper and lower rigid endplate cavity, distribution has 4～8 through holes being similar to hole 1g and hole 2g respectively.In integration formed in situ process, there is the elastomer of mobility or presoma can be full of the through hole of the groove of upper and lower rigid endplate cavity inner surface, projection and outer wall and lower structure, form the integral structure of elastomer-rigid endplate chimeric cladding mutually, be prevented effectively from cervical artificial disc and produce the material damage because interface friction causes and abrasive dust hidden danger when long-time use.
The surface (1a) that described upper rigid endplate contacts with vertebra is cambered surface, and the radius of cambered surface is 10～30mm, and the surface (2a) that lower rigid endplate contacts with vertebra is the cambered surface within the scope of 30～100mm for plane or cambered surface radius.The shape design on upper and lower rigid endplate surface, it can be made consistent with the shape of the bone endplate surface of human vertebrae, the polishing of substantial amounts of vertebra is avoided during implantation, ensure that cervical artificial disc and human vertebrae have bigger contact surface, effectively prevent prosthese from sinking, retain bone soleplate as much as possible, it is achieved overhauling property.The surface that upper and lower rigid endplate contacts with vertebra is furnished with bur (1b) or zigzag stablizes tooth (2b).Described bur is triangular pyramid or rectangular pyramid, is highly 0.5～2mm, and distributed quantity is 4～10.Described zigzag is stablized and is stablized tooth in toothing along the arrangement of A-C direction, has two rows, and the sawtooth quantity often arranged is 3～6, and the height of sawtooth is 0.5～2mm.These burs or zigzag stablize the design of chi, are effectively ensured the Initial stability after cervical artificial disc implants human body, it is to avoid the possibility shift, deviate from.Contain in titanium and hydroxyapatite coating layer on the surface that upper and lower rigid endplate contacts with vertebra one or both, by this spraying, one is to introduce rough surface, is beneficial to growing into of human bone, and two is the growth that can promote bone.
Between the upper and lower rigid endplate of described cervical artificial disc, designing flexible body position limiting structure (3a), its material is identical with elastomer nucleus material, together with the through hole that upper and lower rigid endplate outer wall designs with lower structure is connected as.Elastomer position limiting structure outside-in is certain inclined-plane, and the angle (α) of inclined-plane and horizontal plane ranges for 2～10 °.Internal elastomeric nucleus material is played effect fixing further by this structure on the one hand, on the other hand when the mobility of cervical artificial disc reaches after to a certain degree, cervical artificial disc can be realized elastic spacing, be prevented effectively from because of the damage of the excessive adjacent joints caused of cervical artificial disc mobility.Design from Traditional Man intervertebral disc is different, this position limiting structure has elasticity, after elastomer position limiting structure contact in upper and lower rigid endplate starts, deformation by elastomer self, the mobility of cervical artificial disc can increase further, but the resistance being subject to increased can be gradually increased, and finally plays spacing effect, and whole spacing process can be completed by the mode of transition gradually very smoothly.This position limiting structure so that cervical artificial disc better mates the load-deformation curve of human cervical spine intercalated disc, can accomplish better bionical effect.
In the outside of described cervical artificial disc vertebral pulp, being surrounded by one layer and have elastic polymeric membrane, the thickness range of film is 0.2～1mm.Being designed to of elastic polymeric membrane is grown into effectively preventing human body soft tissue.
Described cervical artificial disc can realize rotating, bending and stretching, translate the activity in three-dimensional six-freedom degree space by the elastic deformation of elastomer nucleus material, the maximum angle scope rotated is not less than 50 °, bend and stretch maximum angle scope and be not less than 15 °, translation maximum displacement is not less than 1mm, elastomer nucleus material can bearing load for a long time, damping vibration effectively, by the elastic deformation of self, every function of simulated implementation human cervical spine intercalated disc well.
Accompanying drawing explanation
Below in conjunction with the drawings and the specific embodiments, the present invention will be further described.
Fig. 1 is cervical artificial disc original position integration formed in situ schematic diagram.
Fig. 2 is preferred embodiment appearance assumption diagram in the present invention.
Fig. 3 is the elastic spacing structural representation in the present invention.
Fig. 4 is the upper rigid endplate top view of preferred embodiment in the present invention.
Fig. 5 is the upper rigid endplate upward view of preferred embodiment in the present invention.
Fig. 6 is the lower rigid endplate upward view of preferred embodiment in the present invention.
Fig. 7 is the lower rigid endplate top view of preferred embodiment in the present invention.
Fig. 8 is the peplos material structure figure of cervical artificial disc in the present invention.
Fig. 9 is the schematic diagram in the present invention after preferred embodiment implantation vertebra.
Figure 10 is schematic diagram of the present invention.
Detailed description of the invention
Fig. 1 is the integrated formed in situ schematic diagram of cervical artificial disc in the present invention.In forming process, first upper rigid endplate, lower rigid endplate are placed in closed mould, then matched moulds, the elastomer or elastomer presoma with good fluidity are injected die cavity from sprue gate a, being full of in the cavity gap between upper and lower rigid endplate, then in-situ solidifying reaction at a certain temperature, forms the integral structure of chimeric cladding mutually with upper and lower rigid endplate, then elastomer outer film material is fixed in cervical artificial disc, obtains final cervical artificial disc product.Fig. 2 is the appearance assumption diagram of one of them preferred embodiment, and in Fig. 2, structure 1 is upper rigid endplate, and structure 2 is lower rigid endplate, and structure 3 is elastomer nucleus material, and structure 4 is translucent elastomer coated fertilizer.
In cervical artificial disc involved in the present invention, devise elastic spacing structure.Fig. 3 is elastic spacing structure schematic diagram operationally.Elastic spacing structure (3a) is held together by pore structure through in upper and lower rigid endplate and elastomer nucleus material, it becomes certain inclined-plane from outside to inside, when cervical artificial disc forerunner, after stretch, the side such as lateral bending reach up to the maximum angle β set time, the inclined-plane of the position limiting structure in upper and lower rigid endplate fits to together, thus cervical artificial disc plays the effect of elastic spacing.Structurally, although elastic spacing structure is connected with elastomer nucleus material by through hole structure, but central elastic gonosome nucleus material bearing load and by deform realize cervical artificial disc mobility in all directions time, elastomer position limiting structure is by the design of upper and lower rigid endplate barrier structure, substantially stress and deformation it are not involved in, only after cervical artificial disc activity reaches capacity, participate in elastic spacing effect, it is to avoid because of the movable excessive damage to adjacent joints of cervical artificial disc.
The upward view of the upper rigid endplate top view of some preferred embodiments and lower rigid endplate in Fig. 4 and Fig. 6 respectively present invention.The contour structure of upper and lower rigid endplate is similar to the contour structure of human vertebrae, it is ensured that cervical artificial disc and human vertebrae have maximum contact area.Above rigid endplate is example, on the surface that upper rigid endplate contacts with human vertebrae, is coated with the titanium or hydroxyapatite coating layer that are beneficial to Bone Ingrowth equably, as shown in Fig. 4 a1.On the surface of upper rigid endplate, it is provided with two gang saw profiles of tooth and stablizes tooth (4a2) or bur class stablizes tooth (4b1,4f1), some of which design and be distributed visible Fig. 4 a～Fig. 4 f.Lower rigid endplate is similar to upper rigid endplate to the design of the contact surface of human vertebrae, it is coated with the titanium or hydroxyapatite coating layer that are conducive to Bone Ingrowth, it is provided with two gang saw profiles of tooth and stablizes tooth or bur class stablizes toothing, some of which design and be distributed visible Fig. 6 a～Fig. 6 f.Such design stablizing tooth, it is possible to after being effectively ensured cervical artificial disc implantation human body, there is good Initial stability.
The top view of the upper rigid endplate upward view of some preferred embodiments and lower rigid endplate in Fig. 5 and Fig. 7 respectively present invention.For upper rigid endplate, Fig. 5 a1 is the endplate structure containing cavity that upper rigid endplate contacts side with elastomer nucleus material, and its lateral profile is circular (5a, 5b, 5d) or oval (5c, 5e, 5f), inner side profile is circular, oval or square.In cavity outboard structure, design has the pore structure (Fig. 5 a2) of up/down perforation, and these through holes are circular or oval, are distributed evenly in lower structure.Fig. 5 a5 is the column type boss structure of cavity center, the distributed about of boss in the cavity center of upper rigid endplate has substantial amounts of little projection or groove, these grooves or protruding or be evenly distributed on (Fig. 5 a3 inside cavity with discrete form, 5a4), or to be distributed in (Fig. 5 b1,5c1) inside cavity in the way of concentric ring.For lower rigid endplate, its design structure contacting side with elastomer nucleus material is basic consistent with upper soleplate, Fig. 7 a1 is the endplate structure containing cavity that upper rigid endplate contacts side with elastomer nucleus material, its lateral profile is circular (7a, 7b, 7d) or oval (7c, 7e, 7f), inner side profile is circular, oval or square.In cavity outboard structure, design has the pore structure (Fig. 7 a2) of up/down perforation, and these through holes are circular or oval, are distributed evenly in lower structure.Fig. 7 a5 is the column type boss structure of cavity center, the distributed about of boss in the cavity center of upper rigid endplate has substantial amounts of little projection or groove, these grooves or protruding or be evenly distributed on (Fig. 7 a3 inside cavity with discrete form, 7a4), or to be distributed in (Fig. 7 b1,7c1) inside cavity in the way of concentric ring.The design of this projection or groove, considerably increases the contact area of elastomer nucleus material and upper and lower rigid endplate, realizes the strong bonded of elastomer vertebral pulp and rigid endplate better.
Fig. 8 is the peplos material structure figure of cervical artificial disc in the present invention, the structure of outer film or be cambered outwards structure (Fig. 8 a), or the structure (Fig. 8 b) for concaving, or be accordion structure (Fig. 8 c), its cross section is circular (Fig. 8 d) or oval (Fig. 8 e).
Fig. 9 is the schematic diagram after the cervical artificial disc in the present invention implants human body.Fig. 9 a, 9c are the human vertebrae contacted with cervical artificial disc, and Fig. 9 b is the cervical artificial disc in the present invention.The cambered surface that the upper rigid endplate of cervical artificial disc designs with lower rigid endplate is similar with the cambered surface of the human vertebrae contacted, and after the implantation, cervical artificial disc and human vertebrae have bigger contact surface.Stable toothing on cervical artificial disc surface thrusts in human vertebrae, it is ensured that after implantation, cervical artificial disc has extraordinary Initial stability.
The cervical artificial disc of design in the present invention, adopts the design of original position integrated molding, by the elastic deformation of elastomer nucleus material, it is possible to simulation cervical intervertebral disk motion in all directions well, has the advantages that extraordinary performance is bionical.Cervical artificial disc structural design in the present invention is not limited solely to cervical intervertebral disk, by the slightly adjustment in structure, it is possible to be applied to the design of artificial lumbar disc.
Claims (10)
1. an integral type bionic-type cervical artificial disc, it is characterised in that: include rigid endplate (1), lower rigid endplate (2), the elastomer nucleus material (3) connecting upper and lower rigid endplate and outer layer protection membrane material (4)；The integrated formed in situ of described elastomer nucleus material and upper and lower soleplate, it is first the elastomer or elastomer presoma with mobility are injected between upper and lower rigid endplate, it is full of the cavity in upper and lower rigid endplate, groove, through hole structure, by the curing cross-linking reaction of elastomer or elastomer presoma, closely fix as one with upper and lower rigid endplate.
2. cervical artificial disc according to claim 1, it is characterised in that: there is after described elastomer nucleus material molding the intensity of more than 20MPa, the elastic deformation of more than 200% and the compression set of less than 10%.
3. cervical artificial disc according to claim 1, it is characterised in that: in described upper and lower rigid endplate, the cross section of the soleplate of the side contacted with vertebra is for consistent with vertebra shape of cross section；In described upper and lower rigid endplate, with the soleplate of the side that elastomer nucleus material contacts, containing cavity structure, the cross section of soleplate is circular or oval.
4. cervical artificial disc according to claim 3, it is characterized in that: the cavity center of the side that described upper and lower rigid endplate contacts with elastomer nucleus material, containing the cylindric double-layered central boss stretched within elastomer vertebral pulp, the boss radius of close elastomer nucleus material is more than the boss radius near rigid endplate, and the height of central boss is 1～2.5mm；Cavity inner surface around central boss, is distributed fluted or bulge-structure；In the outside of the cavity of upper and lower rigid endplate, distribution has 4～8 through holes, and near the side of elastomer vertebral pulp in upper and lower rigid endplate cavity, distribution has 4～8 through holes.
5. cervical artificial disc according to claim 1, it is characterised in that: the surface (1a) that described upper rigid endplate contacts with vertebra is cambered surface, and the radius of cambered surface is 10～30mm；The surface (2a) that described lower rigid endplate contacts with vertebra is the cambered surface within the scope of 25～100mm for plane or cambered surface radius.
6. cervical artificial disc according to claim 1, it is characterised in that: the surface that described upper and lower rigid endplate contacts with vertebra is furnished with bur (1b) or zigzag stablizes tooth (2b).Described bur is triangular pyramid or rectangular pyramid, is highly 0.5～2mm, and distributed quantity is 3～8；Described zigzag stablizes tooth two rows, and the sawtooth quantity often arranged is 3～6, and the height of sawtooth is 0.5～2mm.
7. cervical artificial disc according to claim 1, it is characterised in that: one or both in titanium and hydroxyapatite coating layer are contained on the surface that described upper and lower rigid endplate contacts with vertebra.
8. cervical artificial disc according to claim 1, it is characterized in that: described cervical artificial disc contains two annular elastic spacing structures (3a), it is respectively coated by the outside of the close side contacted with elastomer nucleus material of upper and lower rigid endplate, through hole, elastic spacing structure and elastomer nucleus material are connected as a single entity.
9. cervical artificial disc according to claim 1, it is characterised in that: described elastomer position limiting structure is from outside to inside in inclined-plane, and the angle (α) of inclined-plane and horizontal plane ranges for 2～10 °.
10. cervical artificial disc according to claim 1, it is characterised in that: the outside of described cervical artificial disc prosthese, it is surrounded by one layer and there is elastic polymeric membrane, the thickness of film is within the scope of 0.2～1mm.
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| CN106618811A (en) * | 2017-02-22 | 2017-05-10 | 无锡宝莱福医疗器械有限公司 | Functional bionic artificial cervical disc |
| CN106726022A (en) * | 2017-02-22 | 2017-05-31 | 无锡宝莱福医疗器械有限公司 | A kind of artificial intervertebral disk and its forming method without interface friction |
| CN106901876A (en) * | 2017-02-22 | 2017-06-30 | 无锡宝莱福医疗器械有限公司 | A kind of biomimetic type artificial intervertebral disk and its forming method |
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| CN111938880A (en) * | 2020-08-18 | 2020-11-17 | 四川大学华西医院 | Artificial cervical intervertebral disc device and cover film suitable for same |
| CN113017937A (en) * | 2021-03-08 | 2021-06-25 | 吉林大学 | Rigid-flexible coupling buffer bionic intervertebral disc |
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