CN105726153A - Mouse dermis injury modeling tool for medical experiments - Google Patents
Mouse dermis injury modeling tool for medical experiments Download PDFInfo
- Publication number
- CN105726153A CN105726153A CN201610294521.1A CN201610294521A CN105726153A CN 105726153 A CN105726153 A CN 105726153A CN 201610294521 A CN201610294521 A CN 201610294521A CN 105726153 A CN105726153 A CN 105726153A
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- China
- Prior art keywords
- upper clamp
- jaw
- pole
- modeling tool
- lower clamp
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
Abstract
The invention discloses a mouse dermis injury modeling tool for medical experiments. The mouse dermis injury modeling tool comprises an upper clamp body, a lower clamp body, a support rod and a depth control element, wherein the tail part of the upper clamp body and the tail part of the lower clamp body are fixed together; the front ends of the upper clamp body and the lower clamp body form a jaw; the support rod sequentially passes through the front part of the lower clamp body and the front part of the upper clamp body from bottom to top; the depth control element is arranged at the inner side of the jaw, is arranged on the support rod and is used for limiting the inner side depth of the jaw. The mouse dermis injury modeling tool for medical experiments can be used for limiting the shearing area and depth; during the shearing, the required skin level can be sheared; the injury depth can be effectively controlled; the modeling difficulty of a partial dermis injury animal model of a mouse is greatly reduced; the modeling process of the partial dermis injury animal model of the mouse is simplified. In addition, a mouse partial dermis injury modeling tool can also realize the mouse full-layer skin injury modeling through regulating the depth control element and regulating the distance between a picking handle and the upper and lower clamp bodies.
Description
Technical field
The present invention relates to a kind of modeling tool, particularly relate to the mice dermal lesions modeling tool of a kind of medical experiment.
Background technology
Dermal tissue has the effect formed a connecting link, and above holds epidermis, under open subcutaneous tissue, it it is an important level of skin, having importance structurally and functionally and particularity, dermal components can affect the migration of repair cell, break up, sticks and grow, and is the important component part of repair in trauma；Utilize some dermis damage model, it is possible to effectively observe the change of each composition of corium in processes of wound repair and the impact on wound healing thereof.The method at present mainly through using card punch or shears, mice full thickness skin being removed for the foundation of mouse skin damage model, said method cannot set up the animal model of mice some dermis damage, and adopt the method lancinated or strike off epidermis and some dermis, science, accuracy are poor, operation repeatability is not high, and process is loaded down with trivial details.
Summary of the invention
Therefore, it is an object of the invention to provide the mice dermal lesions modeling tool of a kind of medical experiment, area and the degree of depth of shearing can be limited, the skin corium to mice can be directly cut during shearing, can be prevented effectively from hypodermic damage, simplify the modeling process of some dermis injured animal model, greatly reduce operation easier.
The mice dermal lesions modeling tool of the medical experiment of the present invention, including upper clamp, lower clamp, pole and severity control part；The afterbody of described upper clamp and lower clamp is fixed together and makes the front end of upper clamp and lower clamp form jaw；The bottom-up front portion sequentially passing through lower clamp and upper clamp of described pole；Described severity control part is located at the inner side of jaw and is installed on pole for limiting the degree of depth inside mice skin tissue embedding jaw.
Further, described severity control part is fixed on pole, fixing seat that severity control part includes being fixed on pole and with jaw just to and bar shaped barrier plate that strip crevice that shape is formed with jaw matches；The trailing flank of described bar shaped barrier plate is provided with the connecting rod stretched out backward；The leading flank of described fixing seat is provided with the slot for inserting for connecting rod and be slidably matched；The sidewall of described fixing seat correspondence slot is additionally provided with the lock-screw for connecting rod carries out length adjustment and locking positioning；Lock-screw the inner is provided with wedge；Wedge is rotationally connected with lock-screw around the axis of lock-screw；Connecting rod side correspondence wedge is provided with the wedge-shaped slot matched.
Further, also include prizing handle；The upper end of described pole is stretched out by upper clamp end face；The described handle that prizes is articulated with the upper end of pole and prizes and be provided with fulcrum that is downwardly projecting and that be supported in upper clamp end face on rear side of the correspondence pole of handle bottom surface.
Further, also include being connected to upper clamp afterbody and prize prizing handle and to the distance between upper clamp afterbody and then adjust span of jaw to control the adjusting part of damaged area for adjusting between handle.
Further, described adjusting part includes being connected to upper clamp afterbody and prizes regulating band and rotating adjusting knob thus the distance that regulates between upper clamp and lower clamp for what control to adjust strip length between handle.
The invention has the beneficial effects as follows: the mice dermal lesions modeling tool of the medical experiment of the present invention, area and the degree of depth of shearing can be limited, can directly cut during shearing to required skin level, especially corium middle level, can effectively control lesion depths, and do not damage subcutaneous tissue, greatly reduce the modeling difficulty of some dermis injured animal model, simplify the modeling process of mice some dermis damage.
Accompanying drawing explanation
Fig. 1 is the structural representation of the present invention；
Fig. 2 is severity control part structural representation.
Detailed description of the invention
Fig. 1 is the structural representation of the present invention, and Fig. 2 is severity control part structural representation, as shown in the figure: the mice dermal lesions modeling tool of the medical experiment of the present embodiment, including upper clamp 1, lower clamp 2, pole 3 and severity control part 4；The afterbody of described upper clamp 1 and lower clamp 2 is fixed together and makes the front end of upper clamp 1 and lower clamp 2 form jaw 5；The bottom-up front portion sequentially passing through lower clamp 2 and upper clamp 1 of described pole 3；Described severity control part 4 is located at the inner side of jaw 5 and is installed on pole 3 for limiting the degree of depth inside mice skin tissue embedding jaw 5, upper clamp 1 and lower clamp 2 are has certain elastic strip metal plate, upper clamp 1 is relative with the front end of lower clamp 2 to be bent and has blade to form jaw 5 in the edge processing of bending, can manually pinch and hold upper clamp 1 and lower clamp 2 makes jaw 5 be engaged；Limit jaw 5 inside depth and refer to that limiting other objects puts in the degree of depth in jaw 5, the present embodiment is applied to shear mouse skin, therefore the area sheared and the degree of depth can be limited when shearing, can directly cut during shearing to required skin level, especially corium middle level, can effectively control lesion depths, and not damage subcutaneous tissue, greatly reduce the modeling difficulty of some dermis injured animal model, simplify the modeling process of mice some dermis damage；Be as the criterion the side towards left side and jaw place for front, after towards the side on right side and the fixing end place of upper clamp 1 and lower clamp 2 being with Fig. 1.
In the present embodiment, described severity control part 4 is fixed on pole 3, fixing seat 10 that severity control part 4 includes being fixed on pole 3 and with jaw 5 just to and bar shaped barrier plate 11 that strip crevice that shape is formed with jaw 5 matches；The trailing flank of described bar shaped barrier plate 11 is provided with the connecting rod 12 stretched out backward；The leading flank of described fixing seat 10 is provided with the slot for inserting for connecting rod 12 and be slidably matched；The sidewall of the corresponding slot of described fixing seat 10 is additionally provided with the lock-screw 13 for connecting rod 12 carries out length adjustment and locking positioning, the length of connecting rod 12 can be controlled by lock-screw 13 and control whether locked, therefore, it is possible to adjust the bar shaped barrier plate 11 distance to jaw 5, and then adjust the degree of depth inside mice skin tissue embedding jaw 5 as required, the length and width of bar shaped barrier plate is consistent with the length and width of the strip crevice that jaw 5 is formed, it is ensured that mice skin tissue thickness is uniform；Lock-screw 13 the inner is provided with wedge；Wedge is rotationally connected with lock-screw 13 around the axis of lock-screw 13；Connecting rod 12 side correspondence wedge is provided with the wedge-shaped slot matched, wedge-shaped slot extends along connecting rod 12 glide direction, can wedge be pressed in wedge-shaped slot when therefore tightening lock-screw 13, utilize the frictional force between wedge and wedge-shaped slot that connecting rod 12 is positioned, owing between wedge and wedge-shaped slot, contact area is bigger, therefore frictional force is big, and lozenges can be utilized to produce clamping force, and the location making connecting rod 12 is more firm.
In the present embodiment, also include prizing handle 6；The upper end of described pole 3 is stretched out by upper clamp 1 end face；The described handle 6 that prizes is articulated with the upper end of pole 3 and prizes and be provided with fulcrum 7 that is downwardly projecting and that be supported in upper clamp 1 end face on rear side of handle 6 bottom surface correspondence pole 3, form the structure being similar to nail clipper, the lower end of pole 3 is provided with flange and by this flange support in the bottom surface of lower clamp 2, therefore pressing utilizes lever principle to be pressed for 3 times relative to pole by upper clamp 1 when prizing handle 6, jaw 5 is made to be engaged, comparatively laborsaving, it is possible with existing nail clipper structure by further improving the mice dermal lesions modeling tool of the medical experiment obtaining the present embodiment simultaneously, save cost of manufacture.
In the present embodiment, also include being connected to upper clamp 1 afterbody and prize prizing handle 6 and to the distance between upper clamp 1 afterbody and then adjust jaw 5 aperture to control the adjusting part of damaged area for adjusting between handle 6, namely damaged area is the section of shear, it is capable of the adjustment of the aperture (i.e. the blade of upper clamp 1 to the distance between the blade of lower clamp 2) of jaw 5, the width of the mouse skin sheared as required is adjusted, effectively control the area of some dermis damage, simple to operation.
In the present embodiment, described adjusting part includes being connected to upper clamp 1 afterbody and prizes and regulate band 8 and for controlling to adjust the rotation adjusting knob 9 of band 8 length thus the distance that regulates between upper clamp 1 and lower clamp 2 between handle 6, to control the skin area of shearing；Rotate adjusting knob 9 and include shell, roller and knob；nullRoller is located in shell and is connected to shell by axis of rotation，Knob is located at case surface and is rotationally connected with shell，The rotating shaft of knob is orthogonal with the rotating shaft of roller，Worm screw co-axially fixed with knob it is provided with in shell，On roller, corresponding worm screw is toothed around and is connected formation worm-and-wheel gear with worm screw by the gear teeth，Therefore can pass through worm screw during Turning knob drives roller to rotate，The auto-lock function pair roller simultaneously utilizing worm-and-wheel gear carries out rotary spacing，Regulate band 8 to be two and be flexible but non-stretchable flexible-belt，Such as woven belt or nylon tape etc.，Wherein one is connected to the shell and upper clamp 1 afterbody that rotate adjusting knob 9，Another is wound in the roller rotating adjusting knob 9 and is connected with prizing handle 6，Therefore Turning knob can change the length regulated with 8 windings，And then adjust upper clamp 1 afterbody aperture to the distance prized between handle 6 and jaw 5，Easy to adjust，Do not interfere with use，Easily improve on existing nail clipper architecture basics，It is beneficial to popularization and application.
Claims (5)
1. the mice dermal lesions modeling tool of a medical experiment, it is characterised in that: include upper clamp, lower clamp, pole and severity control part；The afterbody of described upper clamp and lower clamp is fixed together and makes the front end of upper clamp and lower clamp form jaw；The bottom-up front portion sequentially passing through lower clamp and upper clamp of described pole；Described severity control part is located at the inner side of jaw and is installed on pole, embeds the degree of depth inside jaw for limiting mice skin tissue.
2. the mice dermal lesions modeling tool of medical experiment according to claim 1, it is characterized in that: described severity control part is fixed on pole, fixing seat that severity control part includes being fixed on pole and with jaw just to and bar shaped barrier plate that strip crevice that shape is formed with jaw matches；The trailing flank of described bar shaped barrier plate is provided with the connecting rod stretched out backward；The leading flank of described fixing seat is provided with the slot for inserting for connecting rod and be slidably matched；The sidewall of described fixing seat correspondence slot is additionally provided with the lock-screw for connecting rod carries out length adjustment and locking positioning；Lock-screw the inner is provided with wedge；Wedge is rotationally connected with lock-screw around the axis of lock-screw；Connecting rod side correspondence wedge is provided with the wedge-shaped slot matched.
3. the mice dermal lesions modeling tool of medical experiment according to claim 2, it is characterised in that: also include prizing handle；The upper end of described pole is stretched out by upper clamp end face；The described handle that prizes is articulated with the upper end of pole and prizes and be provided with fulcrum that is downwardly projecting and that be supported in upper clamp end face on rear side of the correspondence pole of handle bottom surface.
4. the mice dermal lesions modeling tool of medical experiment according to claim 3, it is characterised in that: also include being connected to upper clamp afterbody and prize prizing handle and to the distance between upper clamp afterbody and then adjust span of jaw to control the adjusting part of damaged area for adjusting between handle.
5. the mice dermal lesions modeling tool of medical experiment according to claim 4, it is characterised in that: described adjusting part includes being connected to upper clamp afterbody and prizes regulating band and rotating adjusting knob thus the distance that regulates between upper clamp and lower clamp for what control to adjust strip length between handle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610294521.1A CN105726153B (en) | 2016-05-06 | 2016-05-06 | The mouse dermal lesions modeling tool of medical experiment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610294521.1A CN105726153B (en) | 2016-05-06 | 2016-05-06 | The mouse dermal lesions modeling tool of medical experiment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105726153A true CN105726153A (en) | 2016-07-06 |
| CN105726153B CN105726153B (en) | 2017-11-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610294521.1A Expired - Fee Related CN105726153B (en) | 2016-05-06 | 2016-05-06 | The mouse dermal lesions modeling tool of medical experiment |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87211015U (en) * | 1987-07-26 | 1988-05-11 | 山西省人民医院 | Medical forceps for ligaturing blood vessel |
| US5823971A (en) * | 1993-10-29 | 1998-10-20 | Boston Scientific Corporation | Multiple biopsy sampling coring device |
| CN202128560U (en) * | 2011-06-30 | 2012-02-01 | 兰州大学第二医院 | Incision model capable of continuously adjusting different depths for animal experiment |
| CN203169231U (en) * | 2013-04-07 | 2013-09-04 | 山西医科大学 | Expanding forceps for percutaneous tracheostomy surgery |
| CN203290979U (en) * | 2013-05-21 | 2013-11-20 | 中国人民解放军第三军医大学第一附属医院 | Skin fetching forceps |
| CN203416920U (en) * | 2013-09-09 | 2014-02-05 | 孙罗军 | Nail clippers |
| CN205041554U (en) * | 2015-09-28 | 2016-02-24 | 宁波出入境检验检疫局检验检疫技术中心 | Damaged treater of animal skin |
-
2016
- 2016-05-06 CN CN201610294521.1A patent/CN105726153B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87211015U (en) * | 1987-07-26 | 1988-05-11 | 山西省人民医院 | Medical forceps for ligaturing blood vessel |
| US5823971A (en) * | 1993-10-29 | 1998-10-20 | Boston Scientific Corporation | Multiple biopsy sampling coring device |
| CN202128560U (en) * | 2011-06-30 | 2012-02-01 | 兰州大学第二医院 | Incision model capable of continuously adjusting different depths for animal experiment |
| CN203169231U (en) * | 2013-04-07 | 2013-09-04 | 山西医科大学 | Expanding forceps for percutaneous tracheostomy surgery |
| CN203290979U (en) * | 2013-05-21 | 2013-11-20 | 中国人民解放军第三军医大学第一附属医院 | Skin fetching forceps |
| CN203416920U (en) * | 2013-09-09 | 2014-02-05 | 孙罗军 | Nail clippers |
| CN205041554U (en) * | 2015-09-28 | 2016-02-24 | 宁波出入境检验检疫局检验检疫技术中心 | Damaged treater of animal skin |
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| Publication number | Publication date |
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| CN105726153B (en) | 2017-11-14 |
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