CN106264453A - Endoscopic imaging and laser speckle imaging fusion imaging system - Google Patents
Endoscopic imaging and laser speckle imaging fusion imaging system Download PDFInfo
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- CN106264453A CN106264453A CN201610591377.8A CN201610591377A CN106264453A CN 106264453 A CN106264453 A CN 106264453A CN 201610591377 A CN201610591377 A CN 201610591377A CN 106264453 A CN106264453 A CN 106264453A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
Abstract
The invention provides a kind of endoscopic imaging and laser speckle imaging fusion imaging system.This endoscopic imaging includes with laser speckle imaging fusion imaging system: endoscopic imaging subsystem, laser speckle imaging subsystems and image co-registration processing equipment, in endoscopic imaging subsystem, ccd detector and LED light source are peeped on the first end of flexible pipe in being installed in, ccd detector and LED light source are electrically connected with the first image processing apparatus respectively, in laser speckle imaging subsystems, laser module is peeped on the first end of flexible pipe in installing, second image processing apparatus is arranged on the optical path downstream of laser module, first image processing apparatus and the second image processing apparatus are electrically connected with image co-registration processing equipment respectively.Technical scheme can solve laser speckle imaging in prior art be limited to optical imagery light structures and photon penetration depth shallow and cannot be from the external problem being scanned imaging.
Description
Technical field
The present invention relates to medical imaging technology field, in particular it relates to a kind of endoscopic imaging melts with laser speckle imaging
Synthesized image system.
Background technology
Laser speckle contrast imaging technology is, by analysis moving particle, the scattering properties of coherent laser is obtained granule
The technology of movement velocity.Laser speckle contrast imaging can carry out the reality of high-spatial and temporal resolution to the microcirculation blood flow of living body biological
Time whole audience imaging.Owing to having the advantages such as noncontact, hurtless measure, fast imaging, laser speckle imaging technology is highly suitable for blood
The microcirculatory imaging measurement of liquid.Use laser speckle technique can measure blood vessels caliber, vessel density, velocity of blood flow and blood flow to fill
The microcirculation parameters such as note.By investigating the structure of microcirculatory vascular, microcirculation function and metabolic activity, pathology mistake can be studied
In journey, the rule of microcirculation change and pathomechanism thereof, all have important meaning to medical diagnosis on disease, illness analysis and treatment measure
Justice.
Laser speckle blood current imaging belongs to optical imaging field, has quickly, the whole audience, the advantage such as lossless, but is limited to optics
Imaging illumination detecting structure and photon penetration depth, blood flow imaging based on this technology is limited to tissue surface, depth bounds about milli
Rice or hundreds of micron.When needs real-time detection in vivo organism deep tissues or intraluminal tissue (such as coat of the stomach, intestinal wall) blood distribution
And during change, laser speckle blood current imaging obviously cannot be scanned imaging from external.
Summary of the invention
It is an object of the invention to provide a kind of endoscopic imaging and laser speckle imaging fusion imaging system, it is intended to solve
In prior art, laser speckle imaging is limited to optical imagery light structures and photon penetration depth is shallow and cannot carry out from external
The problem of scanning imagery.
For solving above-mentioned technical problem, the technical scheme is that a kind of endoscopic imaging of offer becomes with laser speckle
As fusion of imaging system, including endoscopic imaging subsystem, endoscopic imaging subsystem peep in including flexible pipe, ccd detector,
LED light source and the first image processing apparatus, ccd detector and LED light source are peeped on the first end of flexible pipe in being installed in, CCD visits
Survey device and LED light source is electrically connected with by data line and the first image processing apparatus respectively；Laser speckle imaging subsystems,
Laser speckle imaging subsystems includes laser module and the second image processing apparatus, and laser module peeps the first end of flexible pipe in installing
On, laser module sends laser and irradiates object, and laser module receives the signal light that object reflects, at the second image
Reason device is arranged on the optical path downstream of laser module；At image co-registration processing equipment, the first image processing apparatus and the second image
Reason device is electrically connected with image co-registration processing equipment by data line respectively.
Alternatively, laser module includes: laser instrument；The polarizer, the polarizer is arranged on the going out in light light path of laser instrument；Scanning
Mirror assembly, scanning mirror assembly is arranged on the optical path downstream of the polarizer, and scanning mirror assembly reflection light is to irradiate scanning object；
Detection image-forming assembly, the second image processing apparatus is arranged on the optical path downstream of detection image-forming assembly, and detection image-forming assembly detects also
Receive signal light, and signal light is transmitted to the second image processing apparatus.
Alternatively, scanning mirror assembly includes that the scanning galvanometer, focal lens and the polarization that set gradually along optical path direction divide
Mating plate, scanning galvanometer focus on by focal lens rotatably arranged with the reflection of, polarization spectro sheet after light to irradiate object,
Detection image-forming assembly is arranged between polarization spectro sheet and the second image processing apparatus, and the light of object reflection is through polarization spectro
Detection image-forming assembly is entered after sheet.
Alternatively, detection image-forming assembly includes that analyzer and the micro-imaging portion set gradually, the light of object reflection depend on
Secondary through polarization spectro sheet, analyzer and micro-imaging portion.
Alternatively, laser module also includes neutral colour filter, and neutral colour filter is arranged between the polarizer and scanning galvanometer.
Alternatively, laser module also includes that extender lens group mirror, extender lens group mirror are arranged on scanning galvanometer and neutral filter
Between mating plate.
Alternatively, the first image processing apparatus includes CCD Acquisition Circuit portion and figure pretreatment portion, CCD Acquisition Circuit portion
Being electrically connected with ccd detector, CCD Acquisition Circuit portion is electrically connected with figure pretreatment portion, and figure pretreatment portion melts with image
Conjunction processing equipment is electrically connected with.
Alternatively, the second image processing apparatus includes at original speckle image data acquisition portion and laser speckle imaging data
Reason portion, original speckle image data acquisition portion gathers the signal light that object reflects, original speckle image data acquisition portion
Being electrically connected with laser speckle imaging data process portion, laser speckle imaging data process portion is electrical with image co-registration processing equipment
Connect.
Alternatively, image co-registration processing equipment includes analog to digital conversion circuit portion and microcomputer portion, and analog to digital conversion circuit portion is with micro-
Machine portion is electrically connected with, and analog to digital conversion circuit portion is electrically connected with the first image processing apparatus, analog to digital conversion circuit portion and the second figure
As processing means is electrically connected with.
Alternatively, image co-registration processing equipment also includes pci interface portion, passing through between analog to digital conversion circuit portion and microcomputer portion
Pci interface portion is electrically connected with.
In the present invention, this endoscopic imaging is peeped in being carried out by ccd detector with laser speckle imaging fusion imaging system
Scanning, and be illuminated by LED light source, and carry out laser speckle image scanning, then, first by laser module simultaneously
The data that ccd detector is scanned by image processing apparatus carry out initial image procossing, and the second image processing apparatus is to laser group
The speckle image data of part scanning carry out initial image procossing, then carry out endoscopic imaging by image co-registration processing equipment
And the fusion between laser speckle imaging, thus object is achieved surface imaging and the speckle imaging of internal flow circulation thereof
The fusion of imaging combined, provides accurate pathology imaging data to the pathological changes diagnosis of discrimination objective thing.
Accompanying drawing explanation
Fig. 1 is the endoscopic imaging structural representation frame with the embodiment of laser speckle imaging fusion imaging system of the present invention
Figure；
Fig. 2 is the endoscopic imaging of the present invention and the laser module in the embodiment of laser speckle imaging fusion imaging system
Structural representation.
In the accompanying drawings:
10, endoscopic imaging subsystem；11, flexible pipe is peeped in；12, ccd detector；13, LED light source；
14, the first image processing apparatus；141, CCD Acquisition Circuit portion；142, figure pretreatment portion；
20, laser speckle imaging subsystems；21, laser module；211, laser instrument；212, the polarizer；
213, scanning mirror assembly；2131, scanning galvanometer；2132, focal lens；
2133, polarization spectro sheet；214, detection image-forming assembly；2141, analyzer；
2142, micro-imaging portion；215, neutral colour filter；216, extender lens group mirror；
22, the second image processing apparatus；221, original speckle image data acquisition portion；
222, laser speckle imaging data process portion；30, image co-registration processing equipment；
31, analog to digital conversion circuit portion；32, microcomputer portion；33, pci interface portion；100, object.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, right
The present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, and
It is not used in the restriction present invention.
It should be noted that when element is referred to as " being fixed on " or " being arranged at " another element, and it can be directly separately
On one element or be connected on this another element.When an element is referred to as " being connected to " another element, and it is permissible
It is directly to another element or is indirectly connected on this another element.
Also, it should be noted the orientation term such as left and right, upper and lower in the present embodiment, be only each other relative concept or
With the normal operating condition of product as reference, and should not be regarded as restrictive.
As depicted in figs. 1 and 2, the endoscopic imaging of the present embodiment is peeped in including with laser speckle imaging fusion imaging system
Mirror imaging subsystems 10, laser speckle imaging subsystems 20 and image co-registration processing equipment 30.In the present invention, endoscopic imaging
Subsystem 10 peeps flexible pipe 11, ccd detector 12, LED light source 13 and the first image processing apparatus 14, ccd detector 12 in including
Peeping on the first end of flexible pipe 11 in being installed in LED light source 13, ccd detector 12 and LED light source 13 are passed by data respectively
Defeated line and the first image processing apparatus 14 are electrically connected with, and laser speckle imaging subsystems 20 includes laser module 21 and the second image
Processing means 22, laser module 21 is peeped on the first end of flexible pipe 11 in installing, laser module 21 sends laser and irradiates object
100, and laser module 21 receives the signal light that object 100 reflects, the second image processing apparatus 22 is arranged on laser group
The optical path downstream of part 21, the first image processing apparatus 14 and the second image processing apparatus 22 are respectively by data line and image
Fusion treatment equipment 30 is electrically connected with.
This endoscopic imaging peeps scanning in being carried out by ccd detector 12 with laser speckle imaging fusion imaging system, and
It is illuminated by LED light source 13, and carries out laser speckle image scanning, then, the first figure by laser module 21 simultaneously
The data scanned by ccd detector 12 as processing means 14 carry out initial image procossing, and the second image processing apparatus 22 is to swashing
The speckle image data of optical assembly 21 scanning carry out initial image procossing, in then being carried out by image co-registration processing equipment 30
Fusion between sight glass imaging and laser speckle imaging, thus object 100 is achieved surface imaging and internal flow follows
The fusion of imaging that the speckle imaging of ring combines, provides accurate pathology imaging money to the pathological changes diagnosis of discrimination objective thing 100
Material.
As in figure 2 it is shown, the laser module 21 of this endoscopic imaging and laser speckle imaging fusion imaging system includes laser
Device 211, the polarizer 212, scanning mirror assembly 213 and detection image-forming assembly 214, what the polarizer 212 was arranged on laser instrument 211 goes out light
In light path, scanning mirror assembly 213 is arranged on the optical path downstream of the polarizer 212, and scanning mirror assembly 213 reflects light and sweeps to irradiate
Retouching object 100, the second image processing apparatus 22 is arranged on the optical path downstream of detection image-forming assembly 214, detects image-forming assembly 214
Detect and receive the signal light that object 100 reflects, and the transmission of this signal light is entered to the second image processing apparatus 22
The initial treatment of row image.Owing to the camera lens (i.e. ccd detector 12) of laser module 21 endoscopically enters the interior of human body together
The position (i.e. object 100) of portion's organ is scanned, and can carry out the real-time inspection of scope and intracavity gastrointestinal mucosa blood flow simultaneously
Look into.Sending laser beam by laser instrument 211, obtain polarized light after the polarizer 212, then polarized light is scanned through mirror
Assembly 213 irradiates and scans object 100, and now object 100 reflects signal light, and this signal light is detected as group
Part 214 catches and imaging.
Specifically, scanning mirror assembly 213 includes scanning galvanometer 2131, the focal lens set gradually along optical path direction
2132 and polarization spectro sheet 2133.Scanning galvanometer 2131 rotatably arranged with, the scanning galvanometer 2131 of the present embodiment is arranged on and drives
On motivation structure, scanning galvanometer 2131 is driven to rotate by controlling the motion of drive mechanism, to realize scanning galvanometer 2131 general
Incident luminous reflectance propagates to focal lens 2132.Light is converted into the focusing light of level after focal lens 2132.
Polarization spectro sheet 2133 reflects the light after being focused on by focal lens 2132 to irradiate object 100, detects image-forming assembly 214
Being arranged between polarization spectro sheet 2133 and the second image processing apparatus 22, the light of object 100 reflection is through polarization spectro sheet
Detection image-forming assembly 214 is entered after 2133.
In the present embodiment, laser module 21 also includes neutral colour filter 215 and extender lens group mirror 216, neutral optical filtering
Sheet 215 and extender lens group mirror 216 are in turn arranged between the polarizer 212 and scanning galvanometer 2131.Laser instrument 211 sends
Light is polarized after device 212 polarizes, and light filters through neutral colour filter 215, then by extender lens group mirror 216
After being expanded by light beam, light is carried out reflection by scanning galvanometer 2131 and propagates.
Detection image-forming assembly 214 includes analyzer 2141 and the micro-imaging portion 2142 set gradually, and object 100 reflects
Light sequentially pass through polarization spectro sheet 2133, analyzer 2141 and micro-imaging portion 2142., owing to incident light beam first passes around
The polarizer 212 and obtain polarized light, therefore, in the light of object 100 reflection, only polarized light can pass through analyzer 2141
Enter micro-imaging portion 2142 afterwards.
In traditional speckle imaging system, sample is illuminated by laser with a low-angle inclination angle.And the present embodiment
Endoscopic imaging and laser speckle imaging fusion imaging system are by using a polarization spectro sheet 2133 so that irradiating light can
Impinge perpendicularly on object 100 surface, thus ensure that the light energy distribution of linear light sorurce both sides is more uniform.
As it is shown in figure 1, the first image processing apparatus 14 includes CCD Acquisition Circuit portion 141 and figure pretreatment portion 142, CCD
Acquisition Circuit portion 141 is electrically connected with ccd detector 12, and CCD Acquisition Circuit portion 141 is electrically connected with figure pretreatment portion 142,
After ccd detector 12 scans the surface of object 100, imaging data is gathered by CCD Acquisition Circuit portion 141, and is sent to
Figure pretreatment portion 142 carries out pre-imaging processing, and figure pretreatment portion 142 is electrically connected with image co-registration processing equipment 30.The
Two image processing apparatus 22 include original speckle image data acquisition portion 221 and laser speckle imaging data process portion 222, when swashing
During optical assembly 21 scans object 100, original speckle image data acquisition portion 221 gathers what object 100 reflected
Signal light, original speckle image data acquisition portion 221 is electrically connected with laser speckle imaging data process portion 222, now swashs
Light speckle imaging data process portion 222 carries out pre-imaging processing, laser speckle imaging number to the laser speckle image data gathered
It is electrically connected with image co-registration processing equipment 30 according to process portion 222.Image co-registration processing equipment 30 is by endoscopic imaging and laser
Speckle imaging exports the integrated imaging of object 100 after merging, not only can specify esophagus, stomach, pancreas, gallbladder, liver
Dirty, duodenum, large intestine and the location of disease of pulmonary, etiologic diagnosis, and essence can be provided to gastrointestinal wall and adjacent tissue thereof
The really inspection method of blood flow imaging.
Additionally, CCD Acquisition Circuit portion 141 can also substitute the original speckle image number in laser speckle imaging subsystems 20
Laser speckle image-forming data acquisition is carried out according to collection portion 221, the configuration of simplified system on the basis of guarantee systemic-function is stable,
And the view data of both modalities which is gathered respectively by the speed of control system 60 frames/second.
In the present embodiment, image co-registration processing equipment 30 includes analog to digital conversion circuit portion 31, microcomputer portion 32 and pci interface
Portion 33, is electrically connected with by pci interface portion 33 between analog to digital conversion circuit portion 31 and microcomputer portion 32, analog to digital conversion circuit portion 31 with
First image processing apparatus 14 is electrically connected with, and analog to digital conversion circuit portion 31 is electrically connected with the second image processing apparatus 22.Pass through
Analogue signal is converted into digital signal and carries out image information transmission by analog to digital conversion circuit portion 31, thus has imaging data
Effect fidelity, to realize high-quality laser speckle imaging and endoscopic imaging, and shows the display screen in microcomputer portion 32 in real time
On curtain.
The endoscopic imaging of application the present embodiment and laser speckle imaging fusion imaging system, it is possible to realize image and adopt in real time
Collect, show and store, process (present invention is endoscopic imaging and the process of laser speckle imaging fusion) by multi-modality image fusion,
Realize the Intelligent treatment analysis of pathology, it is possible to pathological picture is carried out real-time transmission, thus realizes remote medical consultation with specialists function.
This endoscopic imaging and laser speckle imaging fusion imaging system both directly can be observed viscous by fujinon electronic video endoscope
The pathological change form on film surface, can carry out again the realtime imaging of gastrointestinal mucosa blood flow, it is achieved optimum, the malignant diseases that gastrointestinal wall occurs
The diagnosis become and discriminating, the degree of depth simultaneously gastrointestinal wall invaded by cancer, spread with or without regional lymph nodes and adjacent tissue's organ,
Transfer offers some clarification.This endoscopic imaging and laser speckle imaging fusion imaging system have general, not damaged and without ionization spoke
The advantage penetrated, it is not necessary to special endoscope support, therefore this endoscopic imaging and laser speckle imaging fusion imaging system can
For any endoscopic system possessing standard rocket passage, application prospect is extensive and simple to operate, flexible, convenient.
These are only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Any amendment, equivalent and the improvement etc. made within principle, should be included within the scope of the present invention.
Claims (10)
1. an endoscopic imaging and laser speckle imaging fusion imaging system, it is characterised in that including:
Endoscopic imaging subsystem (10), described endoscopic imaging subsystem (10) peeps flexible pipe (11), ccd detector in including
(12), LED light source (13) and the first image processing apparatus (14), described ccd detector (12) and described LED light source (13) are all pacified
Be contained in described in peep on the first end of flexible pipe (11), described ccd detector (12) and described LED light source (13) pass through data respectively
Transmission line is electrically connected with described first image processing apparatus (14)；
Laser speckle imaging subsystems (20), described laser speckle imaging subsystems (20) includes laser module (21) and the second figure
As processing means (22), described laser module (21) install described in peep on the first end of flexible pipe (11), described laser module
(21) send laser and irradiate object (100), and described laser module (21) receives the signal that described object (100) reflects
Light, described second image processing apparatus (22) is arranged on the optical path downstream of described laser module (21)；
Image co-registration processing equipment (30), described first image processing apparatus (14) and described second image processing apparatus (22) point
It is not electrically connected with described image co-registration processing equipment (30) by data line.
2. endoscopic imaging as claimed in claim 1 and laser speckle imaging fusion imaging system, it is characterised in that described sharp
Optical assembly (21) including:
Laser instrument (211)；
The polarizer (212), the described polarizer (212) is arranged on the going out in light light path of described laser instrument (211)；
Scanning mirror assembly (213), described scanning mirror assembly (213) is arranged on the optical path downstream of the described polarizer (212), and described
Scanning mirror assembly (213) reflection light is to irradiate scanning object (100)；
Detection image-forming assembly (214), described second image processing apparatus (22) is arranged on the light of described detection image-forming assembly (214)
Downstream, road, described detection image-forming assembly (214) is detected and is received described signal light, and transmits described signal light to the most described
Second image processing apparatus (22).
3. endoscopic imaging as claimed in claim 2 and laser speckle imaging fusion imaging system, it is characterised in that described in sweep
Retouch scanning galvanometer (2131), focal lens (2132) and polarization point that mirror assembly (213) includes setting gradually along optical path direction
Mating plate (2133), described scanning galvanometer (2131) reflects by described focusing rotatably arranged with, described polarization spectro sheet (2133)
Light after post lens (2132) focusing is to irradiate described object (100), and described detection image-forming assembly (214) is arranged on described
Between polarization spectro sheet (2133) and described second image processing apparatus (22), the light that described object (100) reflects is through institute
State polarization spectro sheet (2133) and enter described detection image-forming assembly (214) afterwards.
4. endoscopic imaging as claimed in claim 3 and laser speckle imaging fusion imaging system, it is characterised in that described inspection
Surveying analyzer (2141) and micro-imaging portion (2142) that image-forming assembly (214) includes setting gradually, described object (100) is anti-
The light penetrated sequentially passes through described polarization spectro sheet (2133), described analyzer (2141) and described micro-imaging portion (2142).
5. endoscopic imaging as claimed in claim 3 and laser speckle imaging fusion imaging system, it is characterised in that described sharp
Optical assembly (21) also includes that neutral colour filter (215), described neutral colour filter (215) are arranged on the described polarizer (212) and institute
State between scanning galvanometer (2131).
6. endoscopic imaging as claimed in claim 5 and laser speckle imaging fusion imaging system, it is characterised in that described sharp
Optical assembly (21) also includes that extender lens group mirror (216), described extender lens group mirror (216) are arranged on described scanning galvanometer
(2131) filter between (215) sheet with described neutrality.
7. endoscopic imaging as claimed in claim 1 and laser speckle imaging fusion imaging system, it is characterised in that described the
One image processing apparatus (14) includes CCD Acquisition Circuit portion (141) and figure pretreatment portion (142), described CCD Acquisition Circuit portion
(141) it is electrically connected with described ccd detector (12), described CCD Acquisition Circuit portion (141) and described figure pretreatment portion
(142) being electrically connected with, described figure pretreatment portion (142) is electrically connected with described image co-registration processing equipment (30).
8. endoscopic imaging as claimed in claim 1 and laser speckle imaging fusion imaging system, it is characterised in that described the
Two image processing apparatus (22) include original speckle image data acquisition portion (221) and laser speckle imaging data process portion
(222), described original speckle image data acquisition portion (221) gathers the signal light that described object (100) reflects, described
Original speckle image data acquisition portion (221) is electrically connected with described laser speckle imaging data process portion (222), described laser
Speckle imaging data process portion (222) is electrically connected with described image co-registration processing equipment (30).
9. endoscopic imaging as claimed in claim 1 and laser speckle imaging fusion imaging system, it is characterised in that described figure
As fusion treatment equipment (30) includes analog to digital conversion circuit portion (31) and microcomputer portion (32), analog-digital conversion circuit as described portion (31) and
Microcomputer portion (32) is electrically connected with, and analog-digital conversion circuit as described portion (31) are electrically connected with described first image processing apparatus (14),
Analog-digital conversion circuit as described portion (31) is electrically connected with described second image processing apparatus (22).
10. endoscopic imaging as claimed in claim 9 and laser speckle imaging fusion imaging system, it is characterised in that described
Image co-registration processing equipment (30) also includes pci interface portion (33), analog-digital conversion circuit as described portion (31) and microcomputer portion (32) it
Between by described pci interface portion (33) be electrically connected with.
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| WO2018126497A1 (en) * | 2017-01-09 | 2018-07-12 | 清华大学深圳研究生院 | Tip-modulated endoscopic polarization imaging system and measuring method |
| CN109752377A (en) * | 2019-02-02 | 2019-05-14 | 佛山科学技术学院 | A kind of beam splitting type bimodal projection chromatography tissue blood vessel imaging device and method |
| CN113545735A (en) * | 2021-09-18 | 2021-10-26 | 广州永士达医疗科技有限责任公司 | OCT image display adjustment method and device |
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