CN1225562A - 直接数字式血氧计 - Google Patents

直接数字式血氧计 Download PDF

Info

Publication number
CN1225562A
CN1225562A CN97196522.6A CN97196522A CN1225562A CN 1225562 A CN1225562 A CN 1225562A CN 97196522 A CN97196522 A CN 97196522A CN 1225562 A CN1225562 A CN 1225562A
Authority
CN
China
Prior art keywords
oximeter
voltage signal
digital voltage
light
oxygen saturation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN97196522.6A
Other languages
English (en)
Other versions
CN1160021C (zh
Inventor
米切尔·T·拉森
詹姆斯·L·莱斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Criticare Systems Inc
Original Assignee
Criticare Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Criticare Systems Inc filed Critical Criticare Systems Inc
Publication of CN1225562A publication Critical patent/CN1225562A/zh
Application granted granted Critical
Publication of CN1160021C publication Critical patent/CN1160021C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases

Abstract

本发明是一种用于以增高的速度和精度无创地测量血液中的血氧饱和度的血氧计。该设备包括一个能连接与病人的传感器单元(20)和根据从传感器(20)接收的信号确定血液中的血氧饱和度的血氧计(20)。在本发明中,被测信号被立刻转换为数字值(30)。

Description

直接数字式血氧计
本发明一般涉及一种用于无创测量动脉血氧饱和度的改进的血氧计。更具体讲，本发明涉及用于从由连接于血氧计的传感器设备产生的输入信号直接形成数字信号的方法。
在所有血氧计中，从直接与病人的带血组织如手指或耳垂连接的传感器设备接收输入信号。传感器设备一般包括一个红LED、一个红外LED、和一个或两个光电探测器。来自每个LED的光穿过组织，光电探测器检测穿过组织的光量。被测光对于每个带宽包括两个分量。AC分量代表被测的脉动血的量，DC分量代表非脉动血的量。因此，检查被测光的四个独立分量，以确定动脉血氧饱和度：红DC、红AC、红外DC和红外AC。被测光量被用来根据下式确定病人血液中的血氧饱和度：
         (IR(AC)/IR(DC))/(Red(AC)/Red(DC))
在传统的血氧计中，传感器输出信号被转换为模拟电压，然后被分离为红外和红分量。有些血氧计还分离AC和DC分量。然后用分离的模拟电路对这些信号进行采样、信号分离和滤波。因此在这些系统中，必需仔细匹配模拟分量以把可能由两个电路的增益或频率响应的差别造成的误差最小。
本发明对该方法的改进在于，从至少两个最好三个不同波长的LED接收输入电流信号，并将这些输入信号直接转换为数字电压值，而不首先转换为模拟电压或分离信号。这是通过使用电荷数字化模拟数字转换器来实现的，该转换器具有足够的范围以表示大DC信号，和足够的分辨率以表现小AC信号。该电荷数字化转换器使用电流积分器作为前级，这有助于将输入噪声平均或滤掉。这是对于在传统血氧计中使用的、会放大噪声的从模拟电流到电压转换的改进。
一旦输入电流被转换为数字电压值，则所有输入信号被沿着相同的数字硬件路径，而不是沿着传统方法所需的分离的模拟硬件路径处理。该系统不需要匹配模拟硬件元，因此，进一步减小了潜在误差。而且，一旦信号被数字化，则微处理器能进行传统血氧计所要求的所有信号处理、信号分离、和滤波步骤。这种在模拟信号处理阶段的简化提高了血氧计的速度和精度，通过消除昂贵的模拟元件降低了成本，并通过消除大尺寸的模拟元件减小了血氧计的尺寸。
因此，本发明的一个目的是提供一种用于无创测量液体参数的改进的方法。
本发明的另一目的是提供一种测量动脉血饱和度的改进的方法。
本发明的再一目的提供在由血氧计进行的测量中的改进的速度和精度。
本发明的另一目的是提供输入电流信号的直接的模拟到数字转换，它具有足够的范围以测量大DC信号和足够的分辨率以表现小AC信号，从而可以进行精确测量而减少模拟信号处理。
本发明的另一目的是通过将输入电流信号直接转换为数字电压信号，从而绕过可能放大噪声的电流到电压转换步骤来提供潜在误差的减少。
本发明的再一个目的是通过沿一条数字硬件路径处理所有信号，从而消除对匹配的模拟硬件的需要来提供潜在误差的减少。
本发明的另一目的是提供一种电子电路元件数量减少的改进的血氧计。
本发明的再一目的是通过消除大尺寸的模拟元件，减小血氧计的尺寸。
本发明的另一目的是将来自不同波长的LED的至少两个信号直接转换为数字信号形式。
本发明的这些和其他目的和优点，及其操作的组织和方式将从以下结合附图的详细描述变得更明显。
图1表示与传感器设备连接的直接数字式血氧计的框图；
图2表示与病人连接的传感器设备和直接数字式血氧计。
图1表示根据本发明构造的直接数字式血氧计10，及外部传感器设备20的框图。直接数字式血氧计10包括一个电荷数字化模拟到数字转换器30、一个微处理器40、一个数字模拟转换器/LED驱动器50、和一个快闪EPROM60。为了达到足够的精度，电荷数字化模拟数字转换器30最好将输入模拟信号转换为至少20位的数字信号。
在一个优选实施例中(见图2)传感器20连接于带血组织样本，如病人的手指或耳垂。这里，所示传感器20虽然包括一个红LED70、一个红外LED80、和一个单独的光电探测器90，但是该传感器可以包括三个或更多的不同波长的LED和相关的多个光电探测器。LED70和80由来自微处理器40的数字信号驱动。这些数字信号通过数字模拟转换器/LED驱动器50转换为模拟电压。来自LED70和80的光穿过组织样本，并被光电探测器90检测，光电探测器90产生其幅值与每个带宽中检测的光量成比例的模拟电流信号。然后来自光电探测器90的电流信号被电荷数字化模拟数字转换器30以20位的分辨率数字化，并被送至微处理器40。通过微处理器40中的数字信号处理软件程序进行信号分离、环境干扰识别和消除、以及信号滤波。一旦信号被处理，则微处理器40计算下面的比率值
          (IR(AC)/IR(DC))/(Red(AC)/Red(DC))
其中DC分量代表非脉动血流，AC分量表示脉动血流。微处理器40通过将该结果与存储在快闪EPROM60中的查找表中的值比较确定绝对动脉血氧饱和度。
虽然本发明的优选实施例已示出和描述，但本领域的熟练技术人员很清楚，可以进行各种改变和修改而不脱离所附权利要求书中提出的本发明的范围。
权利要求书
按照条约第19条的修改
1．一种用于无创测量动脉血氧饱和度的血氧计，包括：
一个传感器，包括用于在至少两个波长产生光的至少第一和第二光发射装置；
至少一个光电探测器，用于在所述光穿过有脉动血供给的组织样本后，检测所述光，并用于产生代表所述光的每个波长的吸收的模拟电流信号；
一个模拟数字转换器，用于将所述模拟电流信号转换为数字电压信号；以及
一个处理单元，用于处理所述数字电压信号，以计算动脉血氧饱和度。
2．根据权利要求1的血氧计，其中所述传感器包括在三个波长产生光的LED。
4．根据权利要求1的血氧计，其中所述模拟数字转换器包括一个电荷数字化模拟数字转换器。
5．根据权利要求1的血氧计，其中所述模拟数字转换器具有足够的范围以测量大DC信号，和足够的分辨率以表现调制于DC信号上的小AC信号。
6．根据权利要求1的血氧计，其中所述模拟数字转换器在第一级包括一个电流积分器。
7．根据权利要求1的血氧计，其中所述处理单元包括一个执行软件程序的计算机。
9．据权利要求1的血氧计，还包括用于计算血氧饱和度的存储的查找表。
10．根据权利要求1的血氧计，还包括存储在快闪EPROM中用于计算血氧饱和度的存储的查找表。
11．一种用于无创测量动脉血氧饱和度的方法，包括以下步骤：
产生至少第一和第二波长的光；
将所述光照射于一个有脉动血液供给的组织样本；
在所述光穿过所述组织样本后，检测所述光，并产生一个表示所述光的每个波长的吸收率的模拟电流信号；
然后将所述电流信号转换为数字电压信号；以及
然后处理数字电压信号，以计算动脉血氧饱和度。
19．如权利要求11所述的方法，还包括利用存储的查找表计算血氧饱和度的步骤。
20．如权利要求11所述的方法，还包括在快闪EPROM中存储查找表，并利用该表计算血氧饱和度的步骤。
21．如权利要求11所述的方法，还包括从输入的数字电压信号中识别并滤掉环境噪声的步骤。
22．如权利要求11所述的方法，还包括在将所述电流信号转换为所述输入的数字电压之前，对电流信号进行数学积分的步骤。
23．如权利要求11所述的方法，还包括对数字电压信号进行信号分离，以提供代表第一波长的被测光的第一值和代表第二波长的被测光的第二值的步骤。
24．如权利要求23所述的方法，还包括对第一和第二值进行数字滤波的步骤。

Claims (20)

1．一种用于无创测量动脉血氧饱和度的血氧计，包括：
用于产生至少两个波长的光的装置；
用于将所述光照射于包含脉动血供给的组织样本的装置；
用于在所述光穿过所述组织样本后，检测所述光，并用于产生代表所述光的每个波长的吸收的电流信号的装置；
用于将所述电流信号直接转换为数字电压信号的装置；
用于处理所述数字电压信号的装置；以及用于确定动脉血氧饱和度的装置。
2．根据权利要求1的血氧计，其中所述用于产生光的装置包括在三个频率范围产生光的LED。
3．根据权利要求1的血氧计，其中所述用于检测所述光的装置包括至少一个在两个波长检测光，并根据每个被测光量产生一个电流信号的光电探测器。
4．根据权利要求1的血氧计，其中所述将所述电流信号直接转换为数字电压信号的装置包括一个电荷数字化模拟数字转换器。
5．根据权利要求1的血氧计，其中所述将所述电流信号直接转换为数字电压信号的装置包括一个电荷数字化模拟数字转换器，其具有足够的范围以测量大DC信号和足够的分辨率以表现调制于DC上的小AC信号。
6．根据权利要求1的血氧计，其中所述将所述电流信号直接转换为数字电压信号的装置包括一个包含一个在第一级的电流积分器的电荷数字化模拟数字转换器。
7．根据权利要求1的血氧计，其中所述用于处理所述数字电压信号的装置包括一个执行软件程序的计算机。
8．根据权利要求1的血氧计，其中所述用于处理所述数字电压信号的装置包括一个执行软件程序的计算机。
9．根据权利要求1的血氧计，其中所述用于确定血氧饱和度的装置包括一个利用存储的查找表的计算机。
10．根据权利要求1的血氧计，其中所述用于确定血氧饱和度的装置包括一个利用存储在快闪EPROM中的存储的查找表的计算机。
11．一种无创测量动脉血氧饱和度的方法，包括以下步骤：
提供用于产生至少两个波长的光的装置；
提供用于将所述光照射于包含脉动血供给的组织样本装置；
提供用于在所述光穿过所述组织样本后，检测所述光，并用于产生代表所述光的每个波长的吸收的电流信号的装置；
提供用于将所述电流信号直接转换为数字电压信号的装置；
提供用于处理所述数字电压信号的装置；以及提供用于确定动脉血氧饱和度的装置。
12．根据权利要求11所述的方法，其中所述用于产生光的装置包括在三个频率范围产生光的LED。
13．根据权利要求11所述的方法，其中所述用于检测所述光的装置包括一个或多个在所述至少两个波长检测光，并根据每个被测光量产生一个电流信号的光电探测器。
14．根据权利要求11所述的方法，其中所述将所述电流信号直接转换为数字电压信号的装置包括一个电荷数字化模拟数字转换器。
15．根据权利要求11所述的方法，其中所述将所述电流信号直接转换为数字电压信号的装置包括一个电荷数字化模拟数字转换器，其具有足够的范围以测量大DC信号和足够的分辨率以表现调制于DC上的小AC信号。
16．根据权利要求11所述的方法，其中所述将所述电流信号直接转换为数字电压信号的装置包括一个包含一个在第一级的电流积分器的电荷数字化模拟数字转换器。
17．根据权利要求11所述的方法，其中所述用于处理所述数字电压信号的装置包括一个执行软件程序的计算机。
18．根据权利要求11所述的方法，其中所述用于处理所述数字电压信号的装置包括一个执行由微处理器运行的软件程序的计算机。
19．根据权利要求11所述的方法，其中所述用于确定血氧饱和度的装置包括一个利用存储的查找表的计算机。
20．根据权利要求11所述的方法，其中所述用于确定血氧饱和度的装置包括一个利用存储在快闪EPROM中的查找表的计算机。
CNB971965226A 1996-07-17 1997-07-17 直接数字式血氧计 Expired - Fee Related CN1160021C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/683,617 1996-07-17
US08/683,617 US5842981A (en) 1996-07-17 1996-07-17 Direct to digital oximeter

Publications (2)

Publication Number Publication Date
CN1225562A true CN1225562A (zh) 1999-08-11
CN1160021C CN1160021C (zh) 2004-08-04

Family

ID=24744795

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB971965226A Expired - Fee Related CN1160021C (zh) 1996-07-17 1997-07-17 直接数字式血氧计

Country Status (10)

Country Link
US (1) US5842981A (zh)
EP (1) EP0955869B1 (zh)
JP (1) JP2000514683A (zh)
CN (1) CN1160021C (zh)
AU (1) AU720111B2 (zh)
BR (1) BR9710330A (zh)
CA (1) CA2260928C (zh)
DE (1) DE69724822T2 (zh)
ES (1) ES2206740T3 (zh)
WO (1) WO1998002087A1 (zh)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7187962B2 (en) 2001-06-28 2007-03-06 Hitachi Medical Corporation Biological optical measuring instrument
CN100409803C (zh) * 2003-10-02 2008-08-13 松下电工株式会社 光学式生物体信息测定装置、测定方法以及判定装置
CN102846323A (zh) * 2011-07-01 2013-01-02 中国计量学院 一种基于led的无创血氧饱和度检测仪
CN109154564A (zh) * 2016-05-19 2019-01-04 莱曼微设备有限公司 无创性血液分析
CN109596552A (zh) * 2018-12-24 2019-04-09 中北大学 利用单距离光源-探测器对测量组织血氧饱和度的方法

Families Citing this family (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU658177B2 (en) 1991-03-07 1995-04-06 Masimo Corporation Signal processing apparatus and method
US5490505A (en) 1991-03-07 1996-02-13 Masimo Corporation Signal processing apparatus
MX9702434A (es) 1991-03-07 1998-05-31 Masimo Corp Aparato de procesamiento de señales.
US5632272A (en) 1991-03-07 1997-05-27 Masimo Corporation Signal processing apparatus
EP1905352B1 (en) 1994-10-07 2014-07-16 Masimo Corporation Signal processing method
US8019400B2 (en) 1994-10-07 2011-09-13 Masimo Corporation Signal processing apparatus
US6163715A (en) * 1996-07-17 2000-12-19 Criticare Systems, Inc. Direct to digital oximeter and method for calculating oxygenation levels
US6018673A (en) 1996-10-10 2000-01-25 Nellcor Puritan Bennett Incorporated Motion compatible sensor for non-invasive optical blood analysis
US5855550A (en) 1996-11-13 1999-01-05 Lai; Joseph Method and system for remotely monitoring multiple medical parameters
US9042952B2 (en) 1997-01-27 2015-05-26 Lawrence A. Lynn System and method for automatic detection of a plurality of SPO2 time series pattern types
US8932227B2 (en) 2000-07-28 2015-01-13 Lawrence A. Lynn System and method for CO2 and oximetry integration
US9468378B2 (en) 1997-01-27 2016-10-18 Lawrence A. Lynn Airway instability detection system and method
CA2268571C (en) * 1997-02-07 2010-04-06 General Internet, Inc. Collaborative internet data mining system
US20030208535A1 (en) 2001-12-28 2003-11-06 Appleman Kenneth H. Collaborative internet data mining system
US6002952A (en) 1997-04-14 1999-12-14 Masimo Corporation Signal processing apparatus and method
US9521971B2 (en) 1997-07-14 2016-12-20 Lawrence A. Lynn System and method for automatic detection of a plurality of SPO2 time series pattern types
US20070191697A1 (en) 2006-02-10 2007-08-16 Lynn Lawrence A System and method for SPO2 instability detection and quantification
EP1083822A4 (en) * 1998-06-11 2005-10-12 S P O Medical Equipment Ltd DEVICE FOR DETECTING PHYSIOLOGICAL STRESS AND RELATED METHOD
WO2000001294A1 (en) * 1998-07-04 2000-01-13 Whitland Research Limited Non-invasive measurement of blood analytes
US7400918B2 (en) * 1998-07-04 2008-07-15 Edwards Lifesciences Measurement of blood oxygen saturation
EP1104254A2 (en) 1998-08-13 2001-06-06 Whitland Research Limited Optical device
US6675031B1 (en) 1999-04-14 2004-01-06 Mallinckrodt Inc. Method and circuit for indicating quality and accuracy of physiological measurements
US6339715B1 (en) 1999-09-30 2002-01-15 Ob Scientific Method and apparatus for processing a physiological signal
US6433696B1 (en) * 1999-11-05 2002-08-13 Alto U.S., Inc. Carbon monoxide emitting apparatus, carbon monoxide monitor shutoff, and circuit therefor
US8224412B2 (en) 2000-04-17 2012-07-17 Nellcor Puritan Bennett Llc Pulse oximeter sensor with piece-wise function
US6801797B2 (en) 2000-04-17 2004-10-05 Nellcor Puritan Bennett Incorporated Pulse oximeter sensor with piece-wise function
US6889153B2 (en) 2001-08-09 2005-05-03 Thomas Dietiker System and method for a self-calibrating non-invasive sensor
IL138884A (en) 2000-10-05 2006-07-05 Conmed Corp Pulse oximeter and a method of its operation
US20060195041A1 (en) 2002-05-17 2006-08-31 Lynn Lawrence A Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions
US9053222B2 (en) 2002-05-17 2015-06-09 Lawrence A. Lynn Patient safety processor
US6754516B2 (en) 2001-07-19 2004-06-22 Nellcor Puritan Bennett Incorporated Nuisance alarm reductions in a physiological monitor
US6654621B2 (en) 2001-08-29 2003-11-25 Bci, Inc. Finger oximeter with finger grip suspension system
IL145445A (en) 2001-09-13 2006-12-31 Conmed Corp A method for signal processing and a device for improving signal for noise
US6748254B2 (en) 2001-10-12 2004-06-08 Nellcor Puritan Bennett Incorporated Stacked adhesive optical sensor
ATE479343T1 (de) 2002-10-01 2010-09-15 Nellcor Puritan Bennett Inc Verwendung eines kopfbandes zur spannungsanzeige und system aus oxymeter und kopfband
US7698909B2 (en) 2002-10-01 2010-04-20 Nellcor Puritan Bennett Llc Headband with tension indicator
US7190986B1 (en) 2002-10-18 2007-03-13 Nellcor Puritan Bennett Inc. Non-adhesive oximeter sensor for sensitive skin
US7006856B2 (en) 2003-01-10 2006-02-28 Nellcor Puritan Bennett Incorporated Signal quality metrics design for qualifying data for a physiological monitor
US7016715B2 (en) 2003-01-13 2006-03-21 Nellcorpuritan Bennett Incorporated Selection of preset filter parameters based on signal quality
US7047056B2 (en) 2003-06-25 2006-05-16 Nellcor Puritan Bennett Incorporated Hat-based oximeter sensor
US8412297B2 (en) 2003-10-01 2013-04-02 Covidien Lp Forehead sensor placement
US7120479B2 (en) 2004-02-25 2006-10-10 Nellcor Puritan Bennett Inc. Switch-mode oximeter LED drive with a single inductor
US7190985B2 (en) 2004-02-25 2007-03-13 Nellcor Puritan Bennett Inc. Oximeter ambient light cancellation
US7534212B2 (en) 2004-03-08 2009-05-19 Nellcor Puritan Bennett Llc Pulse oximeter with alternate heart-rate determination
US7194293B2 (en) 2004-03-08 2007-03-20 Nellcor Puritan Bennett Incorporated Selection of ensemble averaging weights for a pulse oximeter based on signal quality metrics
US7277741B2 (en) 2004-03-09 2007-10-02 Nellcor Puritan Bennett Incorporated Pulse oximetry motion artifact rejection using near infrared absorption by water
US9143572B2 (en) 2004-09-17 2015-09-22 About, Inc. Method and system for providing content to users based on frequency of interaction
US20080281298A1 (en) * 2005-02-07 2008-11-13 Andersen David R Electronic support system for biological data sensor
US7392075B2 (en) 2005-03-03 2008-06-24 Nellcor Puritan Bennett Incorporated Method for enhancing pulse oximetry calculations in the presence of correlated artifacts
US8204565B2 (en) * 2005-04-04 2012-06-19 University Of Iowa Research Foundation Reagentless optical analyte detection system
US7590439B2 (en) 2005-08-08 2009-09-15 Nellcor Puritan Bennett Llc Bi-stable medical sensor and technique for using the same
US7657295B2 (en) 2005-08-08 2010-02-02 Nellcor Puritan Bennett Llc Medical sensor and technique for using the same
US7657294B2 (en) 2005-08-08 2010-02-02 Nellcor Puritan Bennett Llc Compliant diaphragm medical sensor and technique for using the same
US20070060808A1 (en) 2005-09-12 2007-03-15 Carine Hoarau Medical sensor for reducing motion artifacts and technique for using the same
US7725147B2 (en) 2005-09-29 2010-05-25 Nellcor Puritan Bennett Llc System and method for removing artifacts from waveforms
US7869850B2 (en) 2005-09-29 2011-01-11 Nellcor Puritan Bennett Llc Medical sensor for reducing motion artifacts and technique for using the same
US7899510B2 (en) 2005-09-29 2011-03-01 Nellcor Puritan Bennett Llc Medical sensor and technique for using the same
US8092379B2 (en) 2005-09-29 2012-01-10 Nellcor Puritan Bennett Llc Method and system for determining when to reposition a physiological sensor
US7725146B2 (en) 2005-09-29 2010-05-25 Nellcor Puritan Bennett Llc System and method for pre-processing waveforms
US7904130B2 (en) 2005-09-29 2011-03-08 Nellcor Puritan Bennett Llc Medical sensor and technique for using the same
US7483731B2 (en) 2005-09-30 2009-01-27 Nellcor Puritan Bennett Llc Medical sensor and technique for using the same
US7555327B2 (en) 2005-09-30 2009-06-30 Nellcor Puritan Bennett Llc Folding medical sensor and technique for using the same
US7881762B2 (en) 2005-09-30 2011-02-01 Nellcor Puritan Bennett Llc Clip-style medical sensor and technique for using the same
US7486979B2 (en) 2005-09-30 2009-02-03 Nellcor Puritan Bennett Llc Optically aligned pulse oximetry sensor and technique for using the same
US20070106126A1 (en) 2005-09-30 2007-05-10 Mannheimer Paul D Patient monitoring alarm escalation system and method
US8233954B2 (en) 2005-09-30 2012-07-31 Nellcor Puritan Bennett Llc Mucosal sensor for the assessment of tissue and blood constituents and technique for using the same
US8062221B2 (en) 2005-09-30 2011-11-22 Nellcor Puritan Bennett Llc Sensor for tissue gas detection and technique for using the same
US20070100220A1 (en) 2005-10-28 2007-05-03 Baker Clark R Jr Adjusting parameters used in pulse oximetry analysis
US7668579B2 (en) 2006-02-10 2010-02-23 Lynn Lawrence A System and method for the detection of physiologic response to stimulation
US8702606B2 (en) 2006-03-21 2014-04-22 Covidien Lp Patient monitoring help video system and method
US8073518B2 (en) 2006-05-02 2011-12-06 Nellcor Puritan Bennett Llc Clip-style medical sensor and technique for using the same
US8380271B2 (en) 2006-06-15 2013-02-19 Covidien Lp System and method for generating customizable audible beep tones and alarms
WO2008002405A2 (en) * 2006-06-16 2008-01-03 Medtor Llc System and method for a non-invasive medical sensor
US20070299323A1 (en) * 2006-06-27 2007-12-27 Martijn Wilco Arns Apparatus for measuring one or more physiological functions of a body and a method using the same
US8145288B2 (en) 2006-08-22 2012-03-27 Nellcor Puritan Bennett Llc Medical sensor for reducing signal artifacts and technique for using the same
US8219170B2 (en) 2006-09-20 2012-07-10 Nellcor Puritan Bennett Llc System and method for practicing spectrophotometry using light emitting nanostructure devices
US8064975B2 (en) 2006-09-20 2011-11-22 Nellcor Puritan Bennett Llc System and method for probability based determination of estimated oxygen saturation
US8175671B2 (en) 2006-09-22 2012-05-08 Nellcor Puritan Bennett Llc Medical sensor for reducing signal artifacts and technique for using the same
US8190225B2 (en) 2006-09-22 2012-05-29 Nellcor Puritan Bennett Llc Medical sensor for reducing signal artifacts and technique for using the same
US8396527B2 (en) 2006-09-22 2013-03-12 Covidien Lp Medical sensor for reducing signal artifacts and technique for using the same
US7869849B2 (en) 2006-09-26 2011-01-11 Nellcor Puritan Bennett Llc Opaque, electrically nonconductive region on a medical sensor
US7574245B2 (en) 2006-09-27 2009-08-11 Nellcor Puritan Bennett Llc Flexible medical sensor enclosure
US8696593B2 (en) 2006-09-27 2014-04-15 Covidien Lp Method and system for monitoring intracranial pressure
US7922665B2 (en) 2006-09-28 2011-04-12 Nellcor Puritan Bennett Llc System and method for pulse rate calculation using a scheme for alternate weighting
US7796403B2 (en) 2006-09-28 2010-09-14 Nellcor Puritan Bennett Llc Means for mechanical registration and mechanical-electrical coupling of a faraday shield to a photodetector and an electrical circuit
US7890153B2 (en) 2006-09-28 2011-02-15 Nellcor Puritan Bennett Llc System and method for mitigating interference in pulse oximetry
US7706896B2 (en) 2006-09-29 2010-04-27 Nellcor Puritan Bennett Llc User interface and identification in a medical device system and method
US8728059B2 (en) 2006-09-29 2014-05-20 Covidien Lp System and method for assuring validity of monitoring parameter in combination with a therapeutic device
US7684842B2 (en) 2006-09-29 2010-03-23 Nellcor Puritan Bennett Llc System and method for preventing sensor misuse
US8068890B2 (en) 2006-09-29 2011-11-29 Nellcor Puritan Bennett Llc Pulse oximetry sensor switchover
US7680522B2 (en) 2006-09-29 2010-03-16 Nellcor Puritan Bennett Llc Method and apparatus for detecting misapplied sensors
US7925511B2 (en) 2006-09-29 2011-04-12 Nellcor Puritan Bennett Llc System and method for secure voice identification in a medical device
US20080081956A1 (en) 2006-09-29 2008-04-03 Jayesh Shah System and method for integrating voice with a medical device
US8160668B2 (en) 2006-09-29 2012-04-17 Nellcor Puritan Bennett Llc Pathological condition detector using kernel methods and oximeters
US8116852B2 (en) 2006-09-29 2012-02-14 Nellcor Puritan Bennett Llc System and method for detection of skin wounds and compartment syndromes
US8175667B2 (en) 2006-09-29 2012-05-08 Nellcor Puritan Bennett Llc Symmetric LED array for pulse oximetry
US7476131B2 (en) 2006-09-29 2009-01-13 Nellcor Puritan Bennett Llc Device for reducing crosstalk
US7848891B2 (en) 2006-09-29 2010-12-07 Nellcor Puritan Bennett Llc Modulation ratio determination with accommodation of uncertainty
US7698002B2 (en) 2006-09-29 2010-04-13 Nellcor Puritan Bennett Llc Systems and methods for user interface and identification in a medical device
US8068891B2 (en) 2006-09-29 2011-11-29 Nellcor Puritan Bennett Llc Symmetric LED array for pulse oximetry
US8032528B2 (en) 2007-01-12 2011-10-04 About Inc. Method and system for managing content submission and publication of content
US8280469B2 (en) 2007-03-09 2012-10-02 Nellcor Puritan Bennett Llc Method for detection of aberrant tissue spectra
US8265724B2 (en) 2007-03-09 2012-09-11 Nellcor Puritan Bennett Llc Cancellation of light shunting
US7894869B2 (en) 2007-03-09 2011-02-22 Nellcor Puritan Bennett Llc Multiple configuration medical sensor and technique for using the same
WO2009064979A2 (en) * 2007-11-14 2009-05-22 Conmed Corporation Method and apparatus for processing a pulsatile biometric signal
US8204567B2 (en) 2007-12-13 2012-06-19 Nellcor Puritan Bennett Llc Signal demodulation
US8352004B2 (en) 2007-12-21 2013-01-08 Covidien Lp Medical sensor and technique for using the same
US8346328B2 (en) 2007-12-21 2013-01-01 Covidien Lp Medical sensor and technique for using the same
US8366613B2 (en) 2007-12-26 2013-02-05 Covidien Lp LED drive circuit for pulse oximetry and method for using same
US8577434B2 (en) 2007-12-27 2013-11-05 Covidien Lp Coaxial LED light sources
US8442608B2 (en) 2007-12-28 2013-05-14 Covidien Lp System and method for estimating physiological parameters by deconvolving artifacts
US8452364B2 (en) 2007-12-28 2013-05-28 Covidien LLP System and method for attaching a sensor to a patient's skin
US8092993B2 (en) 2007-12-31 2012-01-10 Nellcor Puritan Bennett Llc Hydrogel thin film for use as a biosensor
US8199007B2 (en) 2007-12-31 2012-06-12 Nellcor Puritan Bennett Llc Flex circuit snap track for a biometric sensor
US8897850B2 (en) 2007-12-31 2014-11-25 Covidien Lp Sensor with integrated living hinge and spring
US8070508B2 (en) 2007-12-31 2011-12-06 Nellcor Puritan Bennett Llc Method and apparatus for aligning and securing a cable strain relief
US8275553B2 (en) 2008-02-19 2012-09-25 Nellcor Puritan Bennett Llc System and method for evaluating physiological parameter data
US8750953B2 (en) 2008-02-19 2014-06-10 Covidien Lp Methods and systems for alerting practitioners to physiological conditions
US8140272B2 (en) 2008-03-27 2012-03-20 Nellcor Puritan Bennett Llc System and method for unmixing spectroscopic observations with nonnegative matrix factorization
US8437822B2 (en) 2008-03-28 2013-05-07 Covidien Lp System and method for estimating blood analyte concentration
US8292809B2 (en) 2008-03-31 2012-10-23 Nellcor Puritan Bennett Llc Detecting chemical components from spectroscopic observations
US8364224B2 (en) 2008-03-31 2013-01-29 Covidien Lp System and method for facilitating sensor and monitor communication
US8112375B2 (en) 2008-03-31 2012-02-07 Nellcor Puritan Bennett Llc Wavelength selection and outlier detection in reduced rank linear models
JP5474937B2 (ja) 2008-05-07 2014-04-16 ローレンス エー． リン， 医療障害パターン検索エンジン
USD626561S1 (en) 2008-06-30 2010-11-02 Nellcor Puritan Bennett Llc Circular satseconds indicator and triangular saturation pattern detection indicator for a patient monitor display panel
US8071935B2 (en) 2008-06-30 2011-12-06 Nellcor Puritan Bennett Llc Optical detector with an overmolded faraday shield
USD626562S1 (en) 2008-06-30 2010-11-02 Nellcor Puritan Bennett Llc Triangular saturation pattern detection indicator for a patient monitor display panel
US9895068B2 (en) 2008-06-30 2018-02-20 Covidien Lp Pulse oximeter with wait-time indication
US7880884B2 (en) 2008-06-30 2011-02-01 Nellcor Puritan Bennett Llc System and method for coating and shielding electronic sensor components
US7887345B2 (en) 2008-06-30 2011-02-15 Nellcor Puritan Bennett Llc Single use connector for pulse oximetry sensors
US8257274B2 (en) 2008-09-25 2012-09-04 Nellcor Puritan Bennett Llc Medical sensor and technique for using the same
US8364220B2 (en) 2008-09-25 2013-01-29 Covidien Lp Medical sensor and technique for using the same
US8968193B2 (en) 2008-09-30 2015-03-03 Covidien Lp System and method for enabling a research mode on physiological monitors
US20100081904A1 (en) * 2008-09-30 2010-04-01 Nellcor Puritan Bennett Llc Device And Method For Securing A Medical Sensor to An Infant's Head
US8417309B2 (en) 2008-09-30 2013-04-09 Covidien Lp Medical sensor
US8386000B2 (en) 2008-09-30 2013-02-26 Covidien Lp System and method for photon density wave pulse oximetry and pulse hemometry
US8433382B2 (en) 2008-09-30 2013-04-30 Covidien Lp Transmission mode photon density wave system and method
US8914088B2 (en) 2008-09-30 2014-12-16 Covidien Lp Medical sensor and technique for using the same
US8423112B2 (en) 2008-09-30 2013-04-16 Covidien Lp Medical sensor and technique for using the same
US8452366B2 (en) 2009-03-16 2013-05-28 Covidien Lp Medical monitoring device with flexible circuitry
US8221319B2 (en) 2009-03-25 2012-07-17 Nellcor Puritan Bennett Llc Medical device for assessing intravascular blood volume and technique for using the same
US8515515B2 (en) 2009-03-25 2013-08-20 Covidien Lp Medical sensor with compressible light barrier and technique for using the same
US8781548B2 (en) 2009-03-31 2014-07-15 Covidien Lp Medical sensor with flexible components and technique for using the same
US8509869B2 (en) 2009-05-15 2013-08-13 Covidien Lp Method and apparatus for detecting and analyzing variations in a physiologic parameter
US8634891B2 (en) 2009-05-20 2014-01-21 Covidien Lp Method and system for self regulation of sensor component contact pressure
US9010634B2 (en) 2009-06-30 2015-04-21 Covidien Lp System and method for linking patient data to a patient and providing sensor quality assurance
US8505821B2 (en) 2009-06-30 2013-08-13 Covidien Lp System and method for providing sensor quality assurance
US8311601B2 (en) 2009-06-30 2012-11-13 Nellcor Puritan Bennett Llc Reflectance and/or transmissive pulse oximeter
US8391941B2 (en) 2009-07-17 2013-03-05 Covidien Lp System and method for memory switching for multiple configuration medical sensor
US8494786B2 (en) 2009-07-30 2013-07-23 Covidien Lp Exponential sampling of red and infrared signals
US8417310B2 (en) 2009-08-10 2013-04-09 Covidien Lp Digital switching in multi-site sensor
US8428675B2 (en) 2009-08-19 2013-04-23 Covidien Lp Nanofiber adhesives used in medical devices
US8494606B2 (en) 2009-08-19 2013-07-23 Covidien Lp Photoplethysmography with controlled application of sensor pressure
US8704666B2 (en) 2009-09-21 2014-04-22 Covidien Lp Medical device interface customization systems and methods
US8494604B2 (en) 2009-09-21 2013-07-23 Covidien Lp Wavelength-division multiplexing in a multi-wavelength photon density wave system
US8788001B2 (en) 2009-09-21 2014-07-22 Covidien Lp Time-division multiplexing in a multi-wavelength photon density wave system
US8798704B2 (en) 2009-09-24 2014-08-05 Covidien Lp Photoacoustic spectroscopy method and system to discern sepsis from shock
US9554739B2 (en) 2009-09-29 2017-01-31 Covidien Lp Smart cable for coupling a medical sensor to an electronic patient monitor
US8515511B2 (en) 2009-09-29 2013-08-20 Covidien Lp Sensor with an optical coupling material to improve plethysmographic measurements and method of using the same
US8376955B2 (en) 2009-09-29 2013-02-19 Covidien Lp Spectroscopic method and system for assessing tissue temperature
US8930145B2 (en) 2010-07-28 2015-01-06 Covidien Lp Light focusing continuous wave photoacoustic spectroscopy and its applications to patient monitoring
DE102012007417A1 (de) 2012-04-16 2013-10-17 Festo Ag & Co. Kg Sensormodul
US9833146B2 (en) 2012-04-17 2017-12-05 Covidien Lp Surgical system and method of use of the same
WO2014163583A1 (en) * 2013-04-05 2014-10-09 Nitto Denko Corporation METHOD AND APPARATUS FOR DETERMINING SpO2 OF A SUBJECT FROM AN OPTICAL MEASUREMENT
EP3203912B1 (en) 2014-10-10 2021-03-10 Medtor LLC System and method for a non-invasive medical sensor
DE102014117879A1 (de) * 2014-12-04 2016-06-09 Osram Opto Semiconductors Gmbh Pulsoxymetrie-Vorrichtung und Verfahren zum Betreiben einer Pulsoxymetrie-Vorrichtung
CN110520043B (zh) 2016-12-05 2023-04-21 梅迪平斯公司 使用呼吸气体样品进行呼吸测量的系统和方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3638640A (en) * 1967-11-01 1972-02-01 Robert F Shaw Oximeter and method for in vivo determination of oxygen saturation in blood using three or more different wavelengths
CA971768A (en) * 1972-02-01 1975-07-29 Robert F. Shaw Oximeter and method
US3799672A (en) * 1972-09-15 1974-03-26 Us Health Education & Welfare Oximeter for monitoring oxygen saturation in blood
JPS5725217B2 (zh) * 1974-10-14 1982-05-28
CA1037285A (en) * 1975-04-30 1978-08-29 Glenfield Warner Ear oximetry process and apparatus
US4167331A (en) * 1976-12-20 1979-09-11 Hewlett-Packard Company Multi-wavelength incremental absorbence oximeter
JPS5524004A (en) * 1978-06-22 1980-02-20 Minolta Camera Kk Oxymeter
JPS56104646A (en) * 1980-01-25 1981-08-20 Minolta Camera Kk Optical analyzer for forming ratio of element contained in organism
US4357105A (en) * 1980-08-06 1982-11-02 Buffalo Medical Specialties Mfg., Inc. Blood diagnostic spectrophotometer
US4407290A (en) * 1981-04-01 1983-10-04 Biox Technology, Inc. Blood constituent measuring device and method
US4740080A (en) * 1985-03-21 1988-04-26 Abbott Laboratories Analog to digital converter for fluid analyzing apparatus
US4819646A (en) * 1986-08-18 1989-04-11 Physio-Control Corporation Feedback-controlled method and apparatus for processing signals used in oximetry
US4773422A (en) * 1987-04-30 1988-09-27 Nonin Medical, Inc. Single channel pulse oximeter
US4807631A (en) * 1987-10-09 1989-02-28 Critikon, Inc. Pulse oximetry system
US4854699A (en) * 1987-11-02 1989-08-08 Nippon Colin Co., Ltd. Backscatter oximeter
US5299120A (en) * 1989-09-15 1994-03-29 Hewlett-Packard Company Method for digitally processing signals containing information regarding arterial blood flow
US5190038A (en) * 1989-11-01 1993-03-02 Novametrix Medical Systems, Inc. Pulse oximeter with improved accuracy and response time
US5348004A (en) * 1993-03-31 1994-09-20 Nellcor Incorporated Electronic processor for pulse oximeter

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7187962B2 (en) 2001-06-28 2007-03-06 Hitachi Medical Corporation Biological optical measuring instrument
CN1326491C (zh) * 2001-06-28 2007-07-18 株式会社日立医药 生物光学测量仪器
CN100409803C (zh) * 2003-10-02 2008-08-13 松下电工株式会社 光学式生物体信息测定装置、测定方法以及判定装置
US8135447B2 (en) 2003-10-02 2012-03-13 Panasonic Electric Works Co., Ltd. Optical biological information measuring apparatus, optical biological information measuring method, biological information decision apparatus, program and recording medium
CN102846323A (zh) * 2011-07-01 2013-01-02 中国计量学院 一种基于led的无创血氧饱和度检测仪
CN109154564A (zh) * 2016-05-19 2019-01-04 莱曼微设备有限公司 无创性血液分析
CN109596552A (zh) * 2018-12-24 2019-04-09 中北大学 利用单距离光源-探测器对测量组织血氧饱和度的方法
CN109596552B (zh) * 2018-12-24 2021-07-16 中北大学 利用单距离光源-探测器对测量组织血氧饱和度的方法

Also Published As

Publication number Publication date
BR9710330A (pt) 2000-01-11
US5842981A (en) 1998-12-01
DE69724822T2 (de) 2004-07-01
CA2260928A1 (en) 1998-01-22
ES2206740T3 (es) 2004-05-16
WO1998002087A1 (en) 1998-01-22
CN1160021C (zh) 2004-08-04
EP0955869A4 (en) 2001-03-14
AU3802997A (en) 1998-02-09
CA2260928C (en) 2005-05-24
JP2000514683A (ja) 2000-11-07
EP0955869A1 (en) 1999-11-17
DE69724822D1 (de) 2003-10-16
EP0955869B1 (en) 2003-09-10
AU720111B2 (en) 2000-05-25

Similar Documents

Publication Publication Date Title
CN1160021C (zh) 直接数字式血氧计
WO1998002087A9 (en) Direct to digital oximeter
US6748253B2 (en) Oversampling pulse oximeter
US4948248A (en) Blood constituent measuring device and method
CA2179023C (en) Medical sensor with amplitude independent output
EP0314331B1 (en) Pulse oximetry system
CA1324187C (en) Blood monitoring apparatus and methods with amplifier input dark current correction
US7355539B2 (en) Multi-bit ADC with sigma-delta modulation
US9360365B2 (en) Optical sensor device for detecting a pulse of a living body
US5579247A (en) Method and apparatus for decreasing the interference and noise sensitivity of a ratiometric converter type of circuit
CN1335756A (zh) 直接数字式血氧计和用来计算氧合值的方法
US10123744B2 (en) Biosensor
US11344234B2 (en) Circuit arrangement for an optical monitoring system and method for optical monitoring
EP0271340A1 (en) Oximeter apparatus and method for measuring arterial blood constituents
CN108245174A (zh) 一种反射式光电容积波的模拟电路前端模块及检测方法
CN105286793B (zh) 生理信号调理电路和生理信号采集系统
CN104783776B (zh) 生物电与正交正弦波调制多路信号的单路采集装置及方法
CN104783777B (zh) 生物电与正弦波调制多路信号的单路采集装置及方法
JPH10201743A (ja) オキシメータ
KR102485581B1 (ko) 아날로그 전단 회로 및 이를 포함하는 산소 포화도 측정기
AU2021104584A4 (en) A device and method to detect haemoglobin count of a person
JPH0599912A (ja) アナログフイルター装置
CN106419860A (zh) 抬高电平的三角波调制光电容积脉搏波测量装置和方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20040804

Termination date: 20110717