CN1245406A - 用于改进视力及视网膜图象分辨力的设备 - Google Patents

用于改进视力及视网膜图象分辨力的设备 Download PDF

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CN1245406A
CN1245406A CN97181504A CN97181504A CN1245406A CN 1245406 A CN1245406 A CN 1245406A CN 97181504 A CN97181504 A CN 97181504A CN 97181504 A CN97181504 A CN 97181504A CN 1245406 A CN1245406 A CN 1245406A
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aberration
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CN1184926C (zh
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戴维·R·威廉姆斯
梁俊中
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University of Rochester
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/103—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/15—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
    • A61B3/156—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for blocking
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J9/00—Measuring optical phase difference; Determining degree of coherence; Measuring optical wavelength

Abstract

一种用于改进视力及视网膜图象分辨力的设备,包括由激光束(102)在活眼(100)的网膜(101)上产生的点光源。从该视网膜反射的激光束在哈特曼－夏克波阵面传感器(148)的小透镜阵列上被接收,以使每个小透镜在与该小透镜阵列相邻设置的CCD摄象机(146)上形成该视网膜上点光源的空间图象。由CCD摄象机输出的信号被计算机(150)获取,该计算机处理该信号并产生可被用于控制光学补偿装置或波阵面补偿装置(如可变形反射镜(118))的矫正信号。它还可被用来制造接触透镜或眼内透镜,或用于引导外科处置以便矫正眼睛象差。所有这些方法可矫正除散焦及散光之外的象差,允许改进视力及改进眼睛内部的成象。

Description

用于改进视力及视网膜图象分辨力的设备
发明背景
本发明目的在于用来改进视力及视网膜图象分辨力的方法与设备。更准确地说，本发明目的在于用于测量与矫正眼睛波象差以使测得的数据可被用于研制用来改进眼睛光学性能的矫正光学元件的方法与设备。
不管在眼镜及接触透镜的设计中有多么显著的进步，现行的眼科透镜仍然只能矫正散焦与散光。眼镜与接触透镜保留有未矫正的附加象差，比如球面象差、彗形象差以及许多不规则象差。眼睛的这些高级象差不仅使得在视网膜上形成的图象变模糊，从而损害视力，而且还使得从活的人体视网膜取得的图象变模糊。有两种障碍阻止了使用特殊设计的光学元件以矫正眼睛中散焦与散光之外的象差。首先，不可能进行眼睛不规则象差的定量测量。其次，除散焦与散光之外矫正眼睛单色象差的机理未得到证明。
验光师的主观屈光法及客观的自动屈光计只测量散焦与散光。它们不能测量包括用传统眼镜未矫正而遗留的所有象差在内的眼睛全部的波象差。由Walsh等人在Journal of the Optical Society of America A，Vol.1，pp.987-992(1984)公开的客观象差镜(objective aberroscope)提供了完整瞳孔的同期波象差测量，但不能以比大约0.9mm更细小的间隔对瞳孔进行取样(见Charman在Optometry and Vision Science，Vol.68，pp.574-583(1991)中的论述)。而且，用该方法对波象差的快速、自动化计算未做说明。
近来，这里的一位共同发明人与其他人一起，开发了一种测量眼体波象差的设备。在题目为“用哈特曼-夏克波振面传感器对人眼波象差进行的客观测量”的报告(Liang等人发表于J.Opt.Soc.Am.A.，Volume11，number 7，pp.1-9，July 1994，其公开内容结合于此作为参考)中，作者公开了一种哈特曼-夏克波振面传感器，它们被用于通过传感从眼睛射出的、由视网膜对聚焦在黄斑上的光反射而产生的波振面来测量人眼的波象差。使用在此处公开的系统，作者只能测量高达四级的多项式函数。适合高达四级多项式的波振面不能提供眼睛象差的完整描述。这种描述对于精确地计算眼睛的光学特性通常是不够的。这种仪器未曾配备来消除由其它表面(如透镜和眼睛角膜)反射的不需要的光。
以前还有一种以改进共焦扫描激光检眼镜轴向分辨力为目标，用以矫正散焦与散光之外眼睛单色象差的尝试。Bartsch等人在Vision Scienceand its Application，1994，Technical Digest Series，VoL.2(OpticalSociety of America，Washington，D.C.)pp.134-137(1994)中使用了一种使角膜第一表面上的折射归零的眼底接触透镜。可是，这种探索遇到的主要问题是眼的波象差依赖于眼的光学系统到处折射率变化的联合效应。或许由于这个原因，所说明的使用眼底接触透镜用以提高共焦扫描激光检眼镜轴向分辨力的尝试仅是不大的改进。
另一种探索是使用可变形的反射镜，一种在地-基望远镜中成功地补偿大气扰动的装置。在Bille的No.4,838,679美国专利中曾预先建议将一种可变形反射镜使用在与人眼相结合的共焦激光扫描检眼镜中，但未曾建议或公开测量人眼波象差的方法。在Applied Optics，Vol.28，pp.804-808中，Dreher，Bille以及Weinreb只是表明将可变形反射镜使用于眼睛，而且仅仅是矫正眼睛的散光，情况不比使用传统眼科透镜提供的矫正更好。使用光学元件矫正高于二级的单色象差从未达到过。在这两个系统中，均未公开测量眼睛高级象差的适当方法。在由Masters，B.R.，Springer-Verlag编辑的Noninvasive Diagnostic Techniques inOphthalmology，pp.528-547(1990)中，Bille等人建议使用与可变形反射镜结合的波振面传感器，但操作系统从未公开或实现。发明概述及目的
考虑到上述情况，显然，在本领域中需要一种用于生产眼科光学元件的方法与设备，该光学元件能提供超过目前可达到的改进的或超常的视力，以及高分辨力的视网膜图象。因此，本发明的主要目的在于提供一种用于精确测量眼睛更高级象差以及使用由此测得的数据与定做的光学元件一起补偿这些象差的方法与设备。
本发明还有一个目的在于提供一种改进的波振面传感器，这种传感器抑制从视网膜以外的组织反射的光并能提供眼体象差的完整测量。
本发明的进一步目的在于利用这种改进的波振面传感器与可变形反射镜相结合的以反馈方式矫正波象差，从而使对象达到标准的或超常的视力。
本发明又一个主要目的在于提供一种产生高分辨力视网膜图象的方法与设备，它容许显微结构成象人体视网膜中的单细胞尺寸。
简要地说，本发明的所有目的通过提供一用于接收来自眼睛视网膜反射光的系统来达到。瞳孔平面中的波振面在哈特曼-夏克波振面传感器的小透镜阵列平面中被重新创造。小透镜阵列中的每个小透镜被用来形成与该小透镜阵列相邻设置的CCD摄象机上视网膜上点光源的空间图象。按照由激光束在视网膜上产生点光源的形式，眼的波象差以正比于每个小透镜上波阵面的局部倾斜的量移动每个光斑。数字式CCD摄象机的输出被送给计算机，然后由该计算机计算波象差并向可变形反射镜提供信号。在累接的程序(iteralive procedure)之后，该可变形反射镜最终获得与开头所测量的波象差相同的形状，但具有一半的幅值。该变形为适合于将畸变的波阵面弄平成平面波的一种变形，它能改进图象质量。
按照其方法方面，如上所述，本发明的系统首先使用计算机取得CCD图象。然后，该计算机计算由波阵面传感器的每个小透镜形成的光斑的质量中心。计算出每个焦斑(focus spot)在X与Y方向的位移，然后用作倾斜数据，以便与65个Zernik多项式的一次微分之和相符合，使用最小平方法来确定每个多项式的权重。
然后，Zernik多项式用计算出的系数进行加权。在波阵面的符合当中65个多项式包括除柱塞项(piston term)之外径向放大率小于或等于10的全部Zernike模式。
然后被加权的Zernike多项式相加在一起，这导致重建的波象差。该波象差然后在可变形反射镜致动器(actuator)的位置上被评定以便产生矫正信号，如上所述，该矫正信号由计算机传送给波阵面补偿装置或可变形反射镜。这样的反馈环持续接收重建的波象差结果，反馈适合的矫正信号，直至重建的波象差信号的均方根值达到一渐近值，在该数值点上可变形反射镜产生的变形将补偿眼睛的全部检测象差。
当重建的波象差信号达到其渐近值时，最终的象差信号(包括所有的预先产生的信号直至均方根误差达到渐近值)可被用于生产接触透镜以便矫正人眼的全部单色象差，或者用于外科处置。
本发明还可被用来提供视网膜的高分辨力图象。产生这种图象的系统使用的是被指定用于向视网膜盘照明以提供视网膜图象的氪闪光灯，该视网膜图象被可变形反射镜反射到一透镜上并通过一孔阑，以使视网膜的反射图象在第二CCD摄象机上聚焦。由该摄象机产生的信号以同上述与第一CCD摄象机相关的类似方式来取得，并存储于计算机中以供后面的应用。
随着本发明的所有目的、优点及特征在后文中会变得更明显，通过参照下面对本发明及所附的权利要求详细描述并参照附图可以更清楚地明白本发明的性质。附图简述
图1为本发明系统的原理图；
图2为使用图1所示设备用于制造接触透镜或提供视网膜图象的本发明方法的流程图；
图3a-3d分别表示使用本发明的系统在进行适宜的补偿之前与之后波象差及相应的点扩散函数；以及
图4表示在适宜的补偿之前与之后眼睛波象差的Zernike衰变，它表明本发明不仅能矫正二极象差(散焦及散光)，而且还能矫正高级象差。优选实施例的详细描述
现在参见图1，这里以原理图形式示出可被用于改进视觉性能及提供眼睛高分辨力视网膜图象两个方面的本发明的设备。如图1所示，本发明的设备利用哈特曼-夏克波阵面传感器测量眼睛象差，然后在带有光学补偿元件如可变形反射镜的闭合反馈环中对其进行矫正。
为测量眼睛的波象差，由激光器102在视网膜上产生一点光源。来自激光器102的光通过一快门(未示出)进行控制。该激光通过空间滤波器104并由消色差双合透镜106准直。经准直的激光束被偏振分束器110反射，通过透镜112及116并入射到可变形反射镜118上。从可变形反射镜118反射的激光束由透镜120聚焦，通过透镜122与第二分束器124并在瞳孔上以大约1.5mm的直径到达眼球100。眼球100的晶状体在其视网膜101上聚焦该激光束。通过眼球100及透镜122相对于透镜120移动，可能使受测试眼的近视或远视得到矫正。
从视网膜101反射的光在瞳孔上形成畸变的波阵面，该畸变的波阵面由透镜122与120在可变形反射镜的平面内重建，还由透镜116与112在哈特曼-夏克波阵面传感器148的小透镜阵列平面内重建。瞳孔与小透镜的二维阵列148成共轭关系。阵列148中的每个小透镜在CCD摄象机146上形成视网膜上点光源的空间图象。CCD摄象机146将数字化图象传送至计算机150，在此处该数字化图象被存储在RAM中或存储在磁性或其它存储介质上。
象差以同每个小透镜上波阵面的局部倾斜成正比的量移动每个光斑。波阵面的倾斜可从与已知无象差基准相关的那些光斑的位移来确定。波阵面传感器154在同时跨越该扩张瞳孔的217个位置上沿X与Y两个方向测量局部倾斜。根据倾斜的阵列，如下文所述该波象差被重建。
构成波阵面传感器154一部分的分束器110最好具有如偏振分束器那样的构形，以便消除由眼球100角膜的第一表面和其它光学元件(如透镜112、116、120和122)反射的不需要的光。否则这类光会干扰波阵面传感器154的工作并会使测量波象差的自动化作业更困难。
本发明的波阵面传感器154比以往可能有的提供更加完全的眼球象差测量，部分是因为在眼瞳孔中有大量采样被采用。使用本发明的设备已经发现，眼球100含有不能用眼镜或接触透镜矫正的复杂象差，且这样的象差在瞳孔大时很显著。本波阵面传感器154首先测量的五级及更高级的平均象差对眼睛的光学质量具有重大的影响。并且，超出级数的更高级象差是稳定的。这种稳定性是重要的，因为它表明使用静态光学矫正器(如定做的接触透镜)可使象差得到矫正。
一旦波象差被测量，如上所述，即受到与眼球100的瞳孔相共轭的装置的补偿，它能控制瞳孔中不同点上光的相位。如结合图2将进一步详细描述的那样，在软件控制下，计算机150产生一反馈至可变形反射镜118的矫正信号。可变形反射镜118(由Xinetics公司生产的no.RX-170407-C型产品是合用的)与眼球100的瞳孔相共轭并产生变形以补偿眼睛波象差。可变形反射镜118含有一带有安装于背表面上矩形阵列中37个致动器的镀铝玻璃面板。另一方面，可使用液晶装置、微电机反射镜、双压电晶片反射镜或其它适宜的装置以代替可变形反射镜118。
图1的设备使用如下。计算机150通过打开发自激光器102的激光束的路径起动测量过程。从视网膜101返回的光被使用于测量波象差。哈特曼-夏克波阵面传感器148提供眼睛波象差的测量，可变形反射镜118据此而被驱动以对其进行矫正。这一过程由于计算机150而重复进行，以产生适宜的信号而引起可变形反射镜118持续变形直至被测试波象差的均方根误差达到一渐近值，尽管也可能使用其它的准则。在此处，可变形反射镜118取得了适合于对眼睛象差提供波阵面补偿的形状。
还在此处，由计算机150产生的最终的矫正信号可被提供给用于制做接触透镜的接触透镜制做系统152，该接触透镜将重复可变形反射镜118的波阵面补偿特性。本领域的普通技术人员会清楚，这样的接触透镜将成为用于每个要提供补偿的眼睛的定做依据。
现在转向图2，这里以流程图形式表示利用从CCD装置146获得的数据由驻留在计算机150中的软件所执行的步骤。在步骤1中，由计算机150从CCD摄象机中获取数字图象。每个图象由12比特位的512个象素乘512个象素组成。然后在步骤2中，计算机150对由波阵面传感器的每个小透镜形成的光斑的重心进行计算。每个光斑的重心规定它的位置。通过比较在参考图形中与从眼睛获得的图象中各相应光斑的位置，每个聚焦光斑在X与Y两个方向的偏移可被计算出。
接下来在步骤3中，倾斜数据与65个Zernike多项式的一次微分之和相符合，使用最小平方法以确定每个多项式的权重，这与上文提到的由Liang等人在其报告中所讨论的内容类似，虽然他们的方法不包括超过四级的多项式。
然后在步骤4中，用步骤3中计算出来的系数对Zernike多项式加权。波阵面符合中的65个多项式多包括径向倍率小于或等于10的全部Zernike模型，但柱塞项除外。一级Zernike模型为线性项。二级模型为平方项，其对应于常见的象差、散焦及散光。三级模型为立方项，其对应于彗形象差和类似彗差的象差。四级模型包括球面象差以及其它类型的象差。五至十级模型为更高级的、不规则的象差。瞳孔中波阵面中的局部不规则性用这些更高级的Zernike模型来表示。
加权的Zernike多项式在步骤5中相加在一起，以取得重建的波象差。该波象差在可变形反射镜118的致动器的位置上被评定以便在步骤6中产生矫正信号，该矫正信号然后由计算机150传送至波阵面补偿装置，如图1中所示，该波阵面补偿装置最好是可变形反射镜118。该反馈环持续接收重建的波象差结果，反馈适宜的矫正信号直至重建波象差信号中的均方根误差达到一渐近值。在此处，可变形反射镜118如此产生变形，当眼睛通过它看时，它将补偿眼睛100的全部被检测象差。
正如本领域的普通技术人员所了解的那样，眼镜和接触透镜适用于矫正视力，但它们只能矫正眼睛的散焦和有时矫正散光。甚至正常的眼睛也具有用传统的眼镜或接触透镜不能矫正的其它象差。本发明的波阵面传感器154能自动地测量这些象差。因而，使用图1的适合的光学系统容许在散焦与散光之外矫正人眼的单色象差。因此，图1的适合的光学系统在改善视力与提供更清晰的视网膜图象两方面对人眼提供空前的视觉质量。
图3a-3d为波阵面传感器数据的图形，表示本发明适合的光学系统成功地矫正眼睛的象差。图3a与3b分别表示，对于一个被测对象，使用本发明无适宜补偿与有适宜补偿时相对于瞳孔位置的波阵面误差。在有四个受测对象的测试中，适当的补偿使跨过6mm瞳孔的峰至谷波阵面误差平均减少至原来的四分之一。
图3c与3d分别表示无适宜补偿与有适宜补偿时由波象差计算出的点散布函数(PSF)。适当的补偿会增加Strehl比，它正比于PSF的峰值强度，从0.09至0.47。对于全部四个受测眼来说平均增加至近于原来的四倍，从0.06至0.23。补偿之后，所表示的用于该对象的PSF具有2.0微米的半宽度(FWHH)，接近于因单独衍射而期望的1.9微米的数值。本发明提供被认为是人眼从未达到的最好的视觉质量。
图4为与波象差的每个Zernike级相关的，面对四个眼睛平均的均方根波阵面误差曲线图。该均方根波阵面误差由适于高达五级的Zernike级补偿得以降低。眼镜、接触透镜和以往使用可变形反射镜矫正眼睛象差的一种尝试只矫正二级象差(散焦与散光)。
矫正一旦实现，本发明的设备可用于向对象提供超常的视网膜成象质量，在此情况下，该对象通过可变形反射镜118观察可视映象。如使用对于细光栅的对比灵敏度所进行的测量，对于通过本设备的单独观察已获得视力的六倍的改善。通过适合的光学系统，单个人可看见非常高频率的光栅，胜过没有适合光学系统的常态观察的分辨力限度。
另一方面，矫正一旦实现，示于图1中的本发明的设备还可被用于提供视网膜101的高分辨力图象。氪闪光灯138由透镜134、132、130和120在通过分束器124之后成象在眼瞳孔上。氪闪光灯138释放4毫秒的闪光，借此对1度直径的视网膜101上的视网膜盘进行照明。窄带干涉滤光片136对闪光灯138的光谱输出整形。
视网膜101的图象通过分束器124和透镜122与120为已被成形来补偿眼睛象差的可变形反射镜118反射，并且通过透镜116。而后该光被反射镜114反射到透镜140上并且通过孔阑141，被反射的图象在此被透镜142聚焦在CCD装置145上。与被CCD摄象机145收集的光相应的电信号，可以从CCD摄象机146获得数据的光获取系统相类似的方式来获得，然后存储在计算机150中用于后面的使用。该图象然后可在与计算机150相连接的监视器(未示出)上显示和/或传送至与计算机150相连接的适合的打印装置(未示出)。
使用本发明的设备，人的活体视网膜中的单个细胞第一次常规地被分辨。本发明适宜的光学系统提供一种用来以显微立体规模研究正常与病态活体视网膜的非侵入技术。眼底成象的横向分辨力的理论极限正比于扩展瞳孔的直径。如果适宜的补偿是相对例如8mm瞳孔完成的，则横向分辨力将会比相对2.5mm瞳孔增加至3.2倍，典型的瞳孔直径被目前适合的眼底摄影机所使用。
轴向分辨力随着瞳孔直径的平方增长，该轴向分辨力在视网膜的深度方向视力分段中是很关键的。因此，跨越8mm瞳孔完成适宜补偿在理论上可使共焦检眼镜的轴向分辨力比具有2.5mm出瞳的仪器增加至10倍。在深度方面PSF的半宽度(FWHH)为27微米，它接近于光学相干性层析X线照相术的数值，但提供了对于单独光学相干性层析X线照相术不可能有的高横向分辨力方面的附加优点。
本发明设备的成功证明，它还可被用于通过对眼睛光学系统整形来改进视力，如在激光屈光手术中或通过生产定做的光学元件，如接触透镜或眼内透镜。如图1与图2所示，最终的矫正信号可提供给接触透镜或眼内透镜制做系统或激光屈光外科处置152，以代替可变形反射镜118。本领域的熟练技术人员清楚，这样的接触透镜、眼内透镜或外科矫正对每个要提供补偿的眼睛将是定做的。除散焦与散光外的附加象差可用无论是开环还是闭环系统进行矫正。
此处描述的本发明考虑到与所示范的矫正这些象差的方法相结合对人眼的象差进行最完整的描述。本发明的应用有四方面。首先，本发明可被利用来提供对肉眼象差的更精确的测量。第二，本发明可被利用于评估各种矫正眼睛象差的技术，如定做眼镜，定做接触透镜及外科处置的益处。第三，本发明可被使用在光学仪器(如望远镜和双筒镜)、定做的眼镜、定做的接触透镜中改进视力以及使用外科处置，如光反射照相角膜切除术(PRK)来改进视力。第四，本发明可被利用于改进活体视网膜成象的轴向与横向分辨力。现行的眼底照相机存在的问题是，在现有技术中，眼睛象差限制它的分辨力，一种自发明检眼镜以来保留的限制。
虽然在此只对优选的实施方案进行了专门的图解与说明，但应理解，根据上述的技术以及在所附权利要求的权限之内，不脱离本发明的精神与预定范围可对本发明作许多改进和变化。

Claims (28)

1.一种用于确定活眼波象差的波阵面传感器，所述波阵面传感器接收所述眼体视网膜反射的点光源图象，包括：
构成用于接收所述视网膜反射的所述点光源图象及用于产生视网膜上点光源空间图象的小透镜阵列的多个小透镜；所述小透镜阵列如此配置，以使其能对至少五级象差提供分辨力；
一与所述小透镜阵列相邻设置的摄象机，用于观察在所述小透镜阵列的所述多个小透镜的每个小透镜上形成的视网膜上点光源的所述空间图象；以及
一相连的数字数据处理器，以从所述摄象机接收视频输出信号并将其转换成表征所述视网膜上点光源空间图象的数字信号，所述数字数据处理器利用所述表征数字信号进一步对所述眼体的波象差进行计算，以便包括至少五级模型。
2.如权利要求1的波阵面传感器，进一步包括一偏光镜，所述视网膜反射的所述点光源图象在被所述多个小透镜接收之前通过该偏光镜。
3.如权利要求1的波阵面传感器，进一步包括一与所述数字数据处理器相连的光学补偿装置，以致于在所述数字数据处理器的控制之下，所述光学补偿装置被进行调整，以对所述眼体的所述波象差提供波阵面补偿。
4.如权利要求3的波阵面传感器，进一步包括一偏振滤光器，所述视网膜反射的所述点光源图象在被所述多个小透镜接收之前通过该偏振滤光器。
5.如权利要求1的波阵面传感器，其中所述小透镜阵列能够提供高达至少十级波象差的分辨力。
6.如权利要求1的波阵面传感器，其中所述小透镜阵列为具有高达217个小透镜的哈特曼-夏克波阵面传感器。
7.如权利要求1的波阵面传感器，进一步包括至少一个与其相连的接触透镜及眼内透镜制做系统，以便为制做至少一个用于对所述活眼的所述波象差提供波阵面补偿的接触透镜或眼内透镜从所述数字数据处理器接收计算出的波象差。
8.如权利要求1的波阵面传感器，进一步包括与其相连接的外科设备，以从所述数字数据处理器接收计算出的波象差，供在所述活眼上执行手术以对所述活眼的所述波象差提供波阵面补偿。
9.如权利要求3的设备，其中所述光学补偿装置为可变形反射镜、液晶器件、微电机反射镜和双压电晶片反射镜中的一个。
10.用于制做接触透镜或眼内透镜以矫正活眼至少三级波象差的设备，包括：
用于产生所述活眼视网膜反射的点光源图象的装置；
用于接收所述被反射的点光源图象并将其转换成相应数字信号的装置；
利用所述数字信号用于计算眼体波象差以致包括至少三级模型的数字数据处理器，以及
至少一个与之相连的接触透镜与眼内透镜制做系统，以便为制做至少一个可对所述活眼的所述至少三级波象差提供波阵面补偿的接触透镜或眼内透镜，从所述数字数据处理器接收计算出的波象差。
11.如权利要求10的设备，其中所述产生装置包括形成用于接收所述视网膜反射的所述点光源图象的小透镜阵列的多个小透镜，所述小透镜阵列如此配置，以使其能对至少三级象差提供分辨力。
12.如权利要求10的设备，进一步包括一偏振滤光器，所述视网膜反射的所述点光源图象在被接收所述被反射点光源用的所述装置接收之前通过该偏振滤光器。
13.一种制做接触透镜以矫正活眼的至少三级波象差的方法，包括如下步骤：
产生所述活眼视网膜反射的点光源图象；
接收所述被反射的点光源图象并将其转换成相应的数字信号；
利用所述数字信号计算所述眼体的波象差，致使包括至少三级模型；以及
接收计算出的波象差用于制做至少一个接触透镜，以便对所述活眼的所述至少三级波象差提供波阵面补偿。
14.如权利要求13的方法，进一步包括使所述被反射点光源图象产生偏振的步骤，以便在接收所述被反射点光源图象之前消除从所述活眼角膜反射的杂散光。
15.一种利用波阵面传感器确定活眼波象差的方法，该波阵面传感器接收所述眼体视网膜反射的点光源图象，包括如下步骤：
提供构成用于接收所述视网膜反射的所述点光源图象的小透镜阵列的多个小透镜，所述小透镜阵列如此配置，以使其能对至少五级象差提供分辨力；
接收在所述小透镜阵列的所述多个小透镜的每个小透镜上形成的视网膜上点光源的空间图象，并产生其表征信号；以及
将所述信号转换成表征所述视网膜上点光源空间图象的数字信号，并且利用所述表征数字信号计算所述眼体的波象差，以致包括至少五级模型。
16.如权利要求15的方法，进一步包括使所述被反射点光源图象产生偏振的步骤，以便在所述多个小透镜接收所述被反射点光源图象之前消除从所述活眼角膜反射的杂散光。
17.一种利用波阵面传感器确定活眼波象差的方法，该波阵面传感器接收所述眼体视网膜反射的点光源图象，包括如下步骤：
提供构成用于接收所述视网膜反射的所述点光源图象的小透镜阵列的多个小透镜，所述小透镜阵列如此配置，以使其能对至少三级象差提供分辨力；
接收在所述小透镜阵列的所述多个小透镜的每个小透镜上形成的视网膜上点光源的空间图象，并产生其表征信号；
将所述信号转换成表征所述视网膜上点光源空间图象的数字信号，并且利用所述表征数字信号计算所述眼体的波象差，以便包括至少三级模型，以及
利用所述计算出的所述活眼的至少三级波象差对光学补偿进行调整，以为所述活眼的所述波象差提供波阵面补偿。
18.产生活眼视网膜高分辨力图象用的设备，包括：
用于产生所述活眼视网膜反射点光源图象的装置；
用于接收所述被反射的点光源图象并将其转换为相应数字信号的装置；
用于利用所述数字信号计算至少三级波象差的数字数据处理器；
用于对所述活眼上的视网膜盘照明以产生视网膜盘图象的装置；
用于反射所述视网膜盘图象的光学补偿装置，所述光学补偿装置利用所述计算出的波象差进行调整，以为所述活眼提供对于所述波象差的波阵面补偿；以及
在被所述光学补偿装置反射之后，用于提供所述被反射视网膜盘图象的装置。
19.如权利要求18的设备，其中所述光学补偿装置为可变形反射镜、液晶器件、微电机反射镜及双压电晶片反射镜中的一个。
20.如权利要求18的设备，进一步包括一偏光镜，在被所述多个小透镜接收之前所述视网膜反射的所述点光源图象通过该偏光镜。
21.如权利要求18的设备，其中所述的产生装置包括构成用于接收所述视网膜反射的所述点光源图象的小透镜阵列的多个小透镜，所述小透镜阵列如此配置，以使其能对至少三级象差提供分辨力。
22.一种结合有用于确定活眼波象差的波阵面传感器的光学仪器，所述波阵面传感器接收所述眼体视网膜反射的点光源图象，包括：
构成用于接收所述视网膜反射的所述点光源图象及用于产生视网膜上点光源空间图象的小透镜阵列的多个小透镜；所述小透镜阵列如此配置，以使其能对至少五级象差提供分辨力；
一与所述小透镜阵列相邻设置的摄象机，用于观察在所述小透镜阵列的所述多个小透镜的每个小透镜上形成的视网膜上点光源的所述空间图象，以及
一相连的数字数据处理器，以从所述摄象机接收视频输出信号并将其转换成表征所述视网膜上点光源空间图象的数字信号，所述数字数据处理器利用所述表征数字信号进一步对所述眼体的波象差进行计算，以致包括至少三级模型，因而当所述活眼利用所述光学仪器时视力得到改善。
23.一种产生活眼视网膜上高分辨力图象的方法，包括如下步骤：
产生所述活眼视网膜反射的点光源图象；
接收所述被反射的点光源图象并将其转换为相应的数字信号；
利用所述数字信号计算所述至少三级波象差；
照明所述活眼上的视网膜盘，以产生视网膜盘图象；以及
在光学补偿装置上反射所述视网膜盘图象，所述光学补偿装置如此被调整，以为所述活眼的所述波象差提供波阵面补偿。
24.如权利要求23的方法，进一步包括使所述被反射的点光源图象产生偏振的步骤，以在接收所述被反射的点光源图象之前消除从所述活眼的角膜反射的杂散光。
25.产生活眼视网膜高分辨力图象用的设备，包括：
用于确定所述活眼至少三级波象差及用于产生其表征矫正信号的装置；
用于反射所述视网膜图象并接收所述矫正信号的光学补偿装置，所述光学补偿装置利用所述矫正信号如此进行调整，以为所述活眼提供对于至少三级波象差的波阵面补偿；以及
用于在其被所述光学补偿装置反射之后提供所述视网膜的所述高分辨力图象的装置。
26.用于在活眼的视网膜上完成手术以便矫正波象差的设备，包括：
用于产生所述活眼的所述视网膜的被反射点光源图象的装置；
用于接收所述被反射的点光源图象并将其转换为相应数字信号的装置；
用于利用所述数字信号计算该眼体波象差的数字数据处理器，以及
用于控制激光光源的装置，所述装置被进行连接以接收由所述数字数据处理器计算出的波象差，以便控制所述激光光源的激光对所述视网膜的轰击，以为所述活眼的所述波象差提供波阵面补偿。
27.如权利要求26的设备，其中所述用于产生的装置包括构成用于接收所述视网膜反射的所述点光源图象的小透镜阵列的多个小透镜。
28.如权利要求26的设备，进一步包括一偏振滤光器，所述被反射的视网膜上点光源图象在被用于接收所述被反射点光源的所述装置接收之前通过它。
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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100333685C (zh) * 2000-10-10 2007-08-29 罗切斯特大学 根据波前象差数据确定眼睛折光度
CN100337581C (zh) * 2000-10-02 2007-09-19 庄臣及庄臣视力保护公司 测量波前像差的方法和设备
CN100353907C (zh) * 2001-04-18 2007-12-12 博士伦公司 获得客观式显然验光的装置
CN100374833C (zh) * 2001-05-08 2008-03-12 庄臣及庄臣视力保护公司 用于测量波阵面像差的方法和装置
CN100449349C (zh) * 2005-04-20 2009-01-07 中国人民解放军国防科学技术大学 大口径线阵哈特曼波前传感器
CN101292862B (zh) * 2007-04-25 2012-02-29 江阴龙跃信息科技有限公司 视网膜细胞显微成像系统
CN102551660A (zh) * 2010-12-20 2012-07-11 佳能株式会社 眼底摄像方法和眼底摄像设备
CN103003747A (zh) * 2010-05-06 2013-03-27 赫克斯冈技术中心 尤其用于从飞行器拍摄航空图像的摄像机
CN103431837A (zh) * 2013-08-23 2013-12-11 饶丰 基于哈特曼传感器的人眼轴向色差和横向色差测量装置及其方法
CN103876706A (zh) * 2012-12-21 2014-06-25 光电子有限公司 检眼镜中的改进以及与检眼镜相关的改进
CN111936095A (zh) * 2018-01-26 2020-11-13 罗切斯特大学 折射率整形激光写入过程控制

Families Citing this family (569)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980513A (en) 1994-04-25 1999-11-09 Autonomous Technologies Corp. Laser beam delivery and eye tracking system
US20010041884A1 (en) * 1996-11-25 2001-11-15 Frey Rudolph W. Method for determining and correcting vision
US6271914B1 (en) 1996-11-25 2001-08-07 Autonomous Technologies Corporation Objective measurement and correction of optical systems using wavefront analysis
US5777719A (en) * 1996-12-23 1998-07-07 University Of Rochester Method and apparatus for improving vision and the resolution of retinal images
EP0910986A1 (en) * 1997-10-24 1999-04-28 BRITISH TELECOMMUNICATIONS public limited company Imaging apparatus
US6547395B1 (en) * 1998-02-06 2003-04-15 Wavefront Sciences, Inc. Methods of measuring moving objects and reducing exposure during wavefront measurements
ES2277430T3 (es) * 1998-03-04 2007-07-01 Visx Incorporated Sistema de tratamiento con laser de la presbicia.
US6007204A (en) * 1998-06-03 1999-12-28 Welch Allyn, Inc. Compact ocular measuring system
US6598975B2 (en) * 1998-08-19 2003-07-29 Alcon, Inc. Apparatus and method for measuring vision defects of a human eye
DE69902549T2 (de) * 1998-08-19 2003-04-17 Alcon Inc Gerät und verfahren zur messung von fehlsichtigkeiten eines menschlichen auges
JP4769923B2 (ja) * 1998-12-10 2011-09-07 カール ツァイス メディテック アクチエンゲゼルシャフト 眼内レンズの計算に好適な、眼の軸方向長さ及び／又は角膜の曲率及び／又は前房深さを非接触的に測定するための一体化装置
US6450642B1 (en) 1999-01-12 2002-09-17 California Institute Of Technology Lenses capable of post-fabrication power modification
DE19904753C1 (de) 1999-02-05 2000-09-07 Wavelight Laser Technologie Gm Vorrichtung für die photorefraktive Hornhautchirurgie des Auges zur Korrektur von Sehfehlern höherer Ordnung
FR2791548B1 (fr) * 1999-04-01 2001-07-06 Univ Paris Vii Denis Diderot Dispositif d'observation d'un corps a haute resolution
US6733130B2 (en) 1999-07-02 2004-05-11 E-Vision, Llc Method for refracting and dispensing electro-active spectacles
US6871951B2 (en) * 2000-06-23 2005-03-29 E-Vision, Llc Electro-optic lens with integrated components
US7023594B2 (en) * 2000-06-23 2006-04-04 E-Vision, Llc Electro-optic lens with integrated components
US6491391B1 (en) * 1999-07-02 2002-12-10 E-Vision Llc System, apparatus, and method for reducing birefringence
US6857741B2 (en) * 2002-01-16 2005-02-22 E-Vision, Llc Electro-active multi-focal spectacle lens
US6491394B1 (en) 1999-07-02 2002-12-10 E-Vision, Llc Method for refracting and dispensing electro-active spectacles
US6986579B2 (en) * 1999-07-02 2006-01-17 E-Vision, Llc Method of manufacturing an electro-active lens
US6050687A (en) * 1999-06-11 2000-04-18 20/10 Perfect Vision Optische Geraete Gmbh Method and apparatus for measurement of the refractive properties of the human eye
US6619799B1 (en) 1999-07-02 2003-09-16 E-Vision, Llc Optical lens system with electro-active lens having alterably different focal lengths
US6517203B1 (en) 1999-07-02 2003-02-11 E-Vision, Llc System, apparatus, and method for correcting vision using electro-active spectacles
DE1060703T1 (de) * 1999-06-16 2001-09-06 20 10 Perfect Vision Optische Vorrichtung und Verfahren zur Vorkompensierung von Brechungseigenschaften des menschlichen Auges mit adaptativer optischer Steuerung der Rückkopplung
US7264354B2 (en) * 1999-07-02 2007-09-04 E-Vision, Llc Method and apparatus for correcting vision using an electro-active phoropter
US7775660B2 (en) * 1999-07-02 2010-08-17 E-Vision Llc Electro-active ophthalmic lens having an optical power blending region
US7604349B2 (en) * 1999-07-02 2009-10-20 E-Vision, Llc Static progressive surface region in optical communication with a dynamic optic
US20090103044A1 (en) * 1999-07-02 2009-04-23 Duston Dwight P Spectacle frame bridge housing electronics for electro-active spectacle lenses
US7404636B2 (en) * 1999-07-02 2008-07-29 E-Vision, Llc Electro-active spectacle employing modal liquid crystal lenses
US7988286B2 (en) 1999-07-02 2011-08-02 E-Vision Llc Static progressive surface region in optical communication with a dynamic optic
US6851805B2 (en) * 1999-07-02 2005-02-08 E-Vision, Llc Stabilized electro-active contact lens
US7290876B2 (en) * 1999-07-02 2007-11-06 E-Vision, Llc Method and system for electro-active spectacle lens design
US7290875B2 (en) * 2004-11-02 2007-11-06 Blum Ronald D Electro-active spectacles and method of fabricating same
US20070258039A1 (en) * 1999-07-02 2007-11-08 Duston Dwight P Spectacle frame bridge housing electronics for electro-active spectacle lenses
US6305802B1 (en) 1999-08-11 2001-10-23 Johnson & Johnson Vision Products, Inc. System and method of integrating corneal topographic data and ocular wavefront data with primary ametropia measurements to create a soft contact lens design
DE19938203A1 (de) * 1999-08-11 2001-02-15 Aesculap Meditec Gmbh Verfahren und Vorrichtung zur Korrektur von Sehfehlern des menschlichen Auges
AU6701400A (en) * 1999-08-11 2001-03-13 Asclepion-Meditec Ag Method and device for completely correcting visual defects of the human eye
US6086204A (en) * 1999-09-20 2000-07-11 Magnante; Peter C. Methods and devices to design and fabricate surfaces on contact lenses and on corneal tissue that correct the eye's optical aberrations
FR2798744B1 (fr) * 1999-09-22 2002-04-05 Essilor Int Procede pour determiner la forme d'une lentille de contact ophtalmique de correction des aberrations optiques de l'oeil au-dela de la defocalisation ou de l'astigmatisme et dispositif pour la mise en oeuvre de ce procede
US7233312B2 (en) * 2000-07-31 2007-06-19 Panaseca, Inc. System and method for optimal viewing of computer monitors to minimize eyestrain
US6592223B1 (en) * 1999-10-07 2003-07-15 Panaseca, Inc. System and method for optimal viewing of computer monitors to minimize eyestrain
CA2388014C (en) * 1999-10-21 2013-04-16 Technolas Gmbh Ophthalmologische Systeme Multi-step laser correction of ophthalmic refractive errors
DE60025387T2 (de) * 1999-10-21 2006-07-06 Technolas Gmbh Ophthalmologische Systeme Verfahren sowie einrichtung zur ophthalmischen, refraktiven korrektur
CA2712321C (en) * 1999-10-21 2013-07-30 Technolas Gmbh Ophthalmologische Systeme Iris recognition and tracking for optical treatment
DE19950792A1 (de) 1999-10-21 2001-04-26 Technolas Gmbh Wellenfrontsensor mit Mehrleistungsstrahlmodi und unabhängiger Abgleichkamera
US6199986B1 (en) 1999-10-21 2001-03-13 University Of Rochester Rapid, automatic measurement of the eye's wave aberration
US7237898B1 (en) 1999-10-21 2007-07-03 Bausch & Lomb Incorporated Customized corneal profiling
US6264328B1 (en) 1999-10-21 2001-07-24 University Of Rochester Wavefront sensor with off-axis illumination
DE19954523C2 (de) * 1999-11-12 2002-01-31 Johannes Junger Verfahren zur Oberflächenbearbeitung einer Kontaktlinse zur individuellen Anpassung an das System Auge
EP1104663A3 (en) * 1999-11-15 2005-01-19 Kabushiki Kaisha Topcon Eye aberration characteristic measuring apparatus
DE19958436B4 (de) * 1999-12-03 2014-07-17 Carl Zeiss Meditec Ag Vorrichtung und Verfahren zur aktiven, physiologisch bewerteten, umfassenden Korrektur der Aberrationen des menschlichen Auges
US6563947B1 (en) 1999-12-10 2003-05-13 20/10 Perfect Vision Optische Geraete Gmbh Application specified integrated circuit for use in wavefront detection
US6419671B1 (en) * 1999-12-23 2002-07-16 Visx, Incorporated Optical feedback system for vision correction
WO2001048536A2 (en) * 1999-12-23 2001-07-05 Shevlin Technologies Limited A display device
CN1423546A (zh) * 1999-12-29 2003-06-11 新英格兰验光学院 通过鉴别和校正光学象差阻止近视发展的方法
DE10001131A1 (de) * 2000-01-13 2001-07-19 Wavelight Laser Technologie Ag Vorrichtung für die ophtalmologische Augenbehandlung mit Fixierlichtstrahl
US6452145B1 (en) 2000-01-27 2002-09-17 Aoptix Technologies, Inc. Method and apparatus for wavefront sensing
US6439720B1 (en) 2000-01-27 2002-08-27 Aoptics, Inc. Method and apparatus for measuring optical aberrations of the human eye
US6464364B2 (en) 2000-01-27 2002-10-15 Aoptix Technologies, Inc. Deformable curvature mirror
US6874897B2 (en) * 2000-01-27 2005-04-05 Aoptix Technologies, Inc. Deformable curvature mirror with unipolar-wiring
US6695207B1 (en) * 2000-02-04 2004-02-24 Carroll Boyd Norris, Jr. System for secure, identity authenticated, and immediate financial transactions as well as activation of varied instrumentalities
US7455407B2 (en) * 2000-02-11 2008-11-25 Amo Wavefront Sciences, Llc System and method of measuring and mapping three dimensional structures
US6550917B1 (en) * 2000-02-11 2003-04-22 Wavefront Sciences, Inc. Dynamic range extension techniques for a wavefront sensor including use in ophthalmic measurement
DE10006896A1 (de) * 2000-02-16 2001-08-30 Wavelight Laser Technologie Ag Verfahren zum Herstellen einer künstlichen okularen Linse
US6220707B1 (en) 2000-02-25 2001-04-24 20/10 Perfect Vision Optische Geraete Gmbh Method for programming an active mirror to mimic a wavefront
AUPQ591800A0 (en) * 2000-02-25 2000-03-23 Sola International Holdings Ltd System for prescribing and/or dispensing ophthalmic lenses
US6234631B1 (en) * 2000-03-09 2001-05-22 Lasersight Technologies, Inc. Combination advanced corneal topography/wave front aberration measurement
US6923802B2 (en) * 2000-03-13 2005-08-02 Memphis Eye & Cataract Assoc. System for generating ablation profiles for laser refractive eye surgery
US6394999B1 (en) * 2000-03-13 2002-05-28 Memphis Eye & Cataract Associates Ambulatory Surgery Center Laser eye surgery system using wavefront sensor analysis to control digital micromirror device (DMD) mirror patterns
EP1658829A1 (en) * 2000-03-20 2006-05-24 California Institute of Technology Application of wavefront sensor to lenses capable of post-fabrication power modification
EP1266256B1 (en) * 2000-03-20 2006-06-21 California Institute of Technology Application of wavefront sensor to lenses capable of post-fabrication power modification
US7044944B2 (en) * 2000-03-22 2006-05-16 Alcon Refractivehorizons, Inc. Optimization of ablation correction of an optical system and associated methods
AR032312A1 (es) 2000-03-22 2003-11-05 Alcon Inc Optimizacion de la correccion por ablacion de un sistema optico y metodos asociados
ES2163373B1 (es) * 2000-03-24 2003-04-16 Univ Catalunya Politecnica Dispositivo de medida objetiva de la mejora en la calidad optica del ojo.
US6659613B2 (en) * 2000-03-27 2003-12-09 Board Of Regents, The University Of Texas System Methods and systems for measuring local scattering and aberration properties of optical media
WO2001078585A2 (en) 2000-04-19 2001-10-25 Alcon Universal Ltd. Wavefront sensor for objective measurement of an optical system and associated methods
AR030419A1 (es) * 2000-04-25 2003-08-20 Alcon Inc Metodo y disposicion para mejorar la calidad de datos de imagen de sensor de un frente de onda que emerge de un ojo
US6413276B1 (en) 2000-04-26 2002-07-02 Emmetropia, Inc. Modified intraocular lens and method of correcting optical aberrations therein
US6338559B1 (en) * 2000-04-28 2002-01-15 University Of Rochester Apparatus and method for improving vision and retinal imaging
US6460997B1 (en) 2000-05-08 2002-10-08 Alcon Universal Ltd. Apparatus and method for objective measurements of optical systems using wavefront analysis
EP1280471A4 (en) * 2000-05-09 2009-05-06 Memphis Eye & Cataract Associa METHOD AND SYSTEM FOR CONTROLLING A HIGH-RESOLUTION DIGITAL HIGH-SPEED MICROSPECTIVE EQUIPMENT FOR REFRACTIVE EYE LASER SURGERY
JP4517211B2 (ja) * 2000-05-12 2010-08-04 株式会社トプコン 眼特性測定装置
US6382793B1 (en) 2000-05-20 2002-05-07 Carl Zeiss, Inc. Method and apparatus for measuring a wavefront
US6382795B1 (en) 2000-05-20 2002-05-07 Carl Zeiss, Inc. Method and apparatus for measuring refractive errors of an eye
US6609793B2 (en) * 2000-05-23 2003-08-26 Pharmacia Groningen Bv Methods of obtaining ophthalmic lenses providing the eye with reduced aberrations
JP4459501B2 (ja) 2000-05-23 2010-04-28 エイ・エム・オー・フローニンゲン・ベー・ベー 眼の収差を低減する眼レンズ
US8020995B2 (en) * 2001-05-23 2011-09-20 Amo Groningen Bv Methods of obtaining ophthalmic lenses providing the eye with reduced aberrations
US6685317B2 (en) 2000-06-13 2004-02-03 Massie Research Laboratories, Inc. Digital eye camera
US6544286B1 (en) * 2000-07-18 2003-04-08 Tissue Engineering Refraction, Inc. Pre-fabricated corneal tissue lens method of corneal overlay to correct vision
IL137635A0 (en) * 2000-08-01 2001-10-31 Visionix Ltd Apparatus for interactive optometry
US6566627B2 (en) * 2000-08-11 2003-05-20 Westar Photonics, Inc. Laser method for shaping of optical lenses
US6830712B1 (en) * 2000-08-28 2004-12-14 Johnson & Johnson Vision Care, Inc. Deformable molds and methods for their use in the manufacture of ophthalmic lenses
US6499843B1 (en) * 2000-09-13 2002-12-31 Bausch & Lomb Incorporated Customized vision correction method and business
US6536898B1 (en) * 2000-09-15 2003-03-25 The Regents Of The University Of Colorado Extended depth of field optics for human vision
US6486943B1 (en) * 2000-09-19 2002-11-26 The Schepens Eye Research Institute, Inc. Methods and apparatus for measurement and correction of optical aberration
US6406146B1 (en) 2000-09-21 2002-06-18 Carl Zeiss, Inc. Wavefront refractor simultaneously recording two hartmann-shack images
WO2002024093A1 (en) * 2000-09-21 2002-03-28 Visx, Inc. Enhanced wavefront ablation system
AU2001294818B2 (en) * 2000-09-26 2006-08-17 Calhoun Vision, Inc. Power adjustment of adjustable lens
US6905641B2 (en) * 2000-09-26 2005-06-14 Calhoun Vision, Inc. Delivery system for post-operative power adjustment of adjustable lens
JP3860405B2 (ja) * 2000-09-29 2006-12-20 株式会社ニデック 角膜手術装置
AU2002211728A1 (en) 2000-10-11 2002-04-22 Calhoun Vision, Inc Light adjustable aberration conjugator
US6382797B1 (en) * 2000-10-17 2002-05-07 20/10 Perfect Vision Optische Geraete Gmbh Aberration-free delivery system
US6554425B1 (en) 2000-10-17 2003-04-29 Johnson & Johnson Vision Care, Inc. Ophthalmic lenses for high order aberration correction and processes for production of the lenses
US6428533B1 (en) * 2000-10-17 2002-08-06 20/10 Perfect Vision Optische Geraete Gmbh Closed loop control for refractive laser surgery (LASIK)
WO2002034126A1 (en) 2000-10-20 2002-05-02 Wavefront Sciences, Inc. Method for computing visual performance from objective ocular aberration measurements
US6464357B1 (en) * 2000-10-20 2002-10-15 Kestrel Corporation Wavefront characterization of corneas
US6827444B2 (en) 2000-10-20 2004-12-07 University Of Rochester Rapid, automatic measurement of the eye's wave aberration
WO2002034178A1 (en) * 2000-10-20 2002-05-02 Bausch & Lomb Incorporated Method and system for improving vision
US6695880B1 (en) 2000-10-24 2004-02-24 Johnson & Johnson Vision Care, Inc. Intraocular lenses and methods for their manufacture
WO2002035995A2 (en) 2000-10-30 2002-05-10 Johnson & Johnson Vision Care, Inc. Wavefront measurement
US7152975B2 (en) * 2000-11-10 2006-12-26 Cooper Vision, Inc. Junctionless ophthalmic lenses and methods for making same
US6595639B1 (en) 2000-11-10 2003-07-22 Ocular Sciences, Inc. Junctionless ophthalmic lenses and methods for making same
US7293871B2 (en) * 2000-11-27 2007-11-13 Ophthonix, Inc. Apparatus and method of correcting higher-order aberrations of the human eye
US6813082B2 (en) 2000-11-27 2004-11-02 Ophthonix, Inc. Wavefront aberrator and method of manufacturing
US6563572B1 (en) * 2000-12-07 2003-05-13 The United States Of America As Represented By The Secretary Of The Air Force Correlating shack-hartmann wavefront sensor
MXPA03005113A (es) 2000-12-08 2004-01-29 Visx Inc Programa de tratamiento de ablacion cornea basado en frente de ondas directo.
US20020071095A1 (en) * 2000-12-08 2002-06-13 Roffman Jefrey H. Composite surface contact lenses
US6547391B2 (en) * 2000-12-08 2003-04-15 Johnson & Johnson Vision Care, Inc. Ocular aberration correction taking into account fluctuations due to biophysical rhythms
SE0004829D0 (sv) * 2000-12-22 2000-12-22 Pharmacia Groningen Bv Methods of obtaining ophthalmic lenses providing the eye with reduced aberrations
JP3797874B2 (ja) * 2000-12-26 2006-07-19 オリンパス株式会社 走査型光学顕微鏡
US6757310B2 (en) 2001-01-17 2004-06-29 Ming Lai Solid-state laser for customized cornea ablation
EP2063311A1 (en) 2001-01-17 2009-05-27 E-Vision, LLC Electro-optic lens with integrated components
US6331059B1 (en) 2001-01-22 2001-12-18 Kestrel Corporation High resolution, multispectral, wide field of view retinal imager
US6736507B2 (en) 2001-01-22 2004-05-18 Alexis Kudryashov High resolution, multispectral, wide field of view retinal imager
US7422714B1 (en) 2001-01-24 2008-09-09 Cornerstone Research Group, Inc. Method of using a shape memory material as a mandrel for composite part manufacturing
DE10103763C2 (de) * 2001-01-27 2003-04-03 Zeiss Carl Meditec Ag Verfahren und Vorrichtung zur subjektiven Bestimmung von Abbildungsfehlern höherer Ordnung
US6361170B1 (en) * 2001-02-14 2002-03-26 Heidelberg Engineering Optische Messysteme Gmbh Aberration-free imaging of the fundus of the human eye
DE60228940D1 (de) * 2001-03-15 2008-10-30 Amo Wavefront Sciences Llc Hren zur abbildung eines optischen systems
SE0101293D0 (sv) * 2001-04-11 2001-04-11 Pharmacia Groningen Bv Technical field of the invention
EP1390802A1 (en) * 2001-04-27 2004-02-25 Novartis AG Automatic lens design and manufacturing system
DE60135879D1 (de) * 2001-04-27 2008-10-30 Bausch & Lomb Iris-mustererkennung und ausrichtung
US6746121B2 (en) * 2001-04-27 2004-06-08 Denwood F. Ross Defocus and astigmatism compensation in a wavefront aberration measurement system
US6394605B1 (en) 2001-05-23 2002-05-28 Alcon Universal Ltd. Fogging method for a wavefront sensor
US6561648B2 (en) * 2001-05-23 2003-05-13 David E. Thomas System and method for reconstruction of aberrated wavefronts
IL143503A0 (en) 2001-05-31 2002-04-21 Visionix Ltd Aberration correction spectacle lens
US7217375B2 (en) * 2001-06-04 2007-05-15 Ophthonix, Inc. Apparatus and method of fabricating a compensating element for wavefront correction using spatially localized curing of resin mixtures
US6595643B2 (en) * 2001-06-05 2003-07-22 Adaptive Optics Associates,.Inc. Ophthalmic imaging instrument that measures and compensates for phase aberrations in reflections derived from light produced by an imaging light source
US6721510B2 (en) 2001-06-26 2004-04-13 Aoptix Technologies, Inc. Atmospheric optical data transmission system
FR2828396B1 (fr) * 2001-08-12 2004-05-07 Samuel Henri Bucourt Dispositif de mesure des aberrations d'un systeme de type oeil
WO2003020121A1 (en) * 2001-08-30 2003-03-13 University Of Rochester Adaptive optics in a scanning lase ophtalmoscope
US6709108B2 (en) * 2001-08-31 2004-03-23 Adaptive Optics Associates, Inc. Ophthalmic instrument with adaptive optic subsystem that measures aberrations (including higher order aberrations) of a human eye and that provides a view of compensation of such aberrations to the human eye
US6827442B2 (en) * 2001-09-12 2004-12-07 Denwood F. Ross Ophthalmic wavefront measuring devices
US6575572B2 (en) 2001-09-21 2003-06-10 Carl Zeiss Ophthalmic Systems, Inc. Method and apparatus for measuring optical aberrations of an eye
BR0213012A (pt) * 2001-10-05 2004-12-28 E Vision Llc Lentes eletro-ativas hìbridas
US6554429B1 (en) 2001-10-15 2003-04-29 Alcon, Inc. Method for determining accommodation
CA2468289C (en) 2001-10-19 2009-06-09 Bausch & Lomb Incorporated Presbyopic vision improvement
EP1902672B1 (en) 2001-10-19 2010-04-28 Bausch & Lomb Incorporated Presbyopic vision improvement
US7434931B2 (en) 2001-10-25 2008-10-14 Ophthonix Custom eyeglass manufacturing method
US6712466B2 (en) * 2001-10-25 2004-03-30 Ophthonix, Inc. Eyeglass manufacturing method using variable index layer
AU2008201900B2 (en) * 2001-10-25 2011-11-24 Essilor International (Compagnie Generale D'optique) Eyeglass having variable index layer
US6682195B2 (en) 2001-10-25 2004-01-27 Ophthonix, Inc. Custom eyeglass manufacturing method
US6688745B2 (en) 2001-10-25 2004-02-10 Johnson & Johnson Vision Care, Inc. Subjective refinement of wavefront measurements
US7226166B2 (en) * 2001-11-13 2007-06-05 Philadelphia Retina Endowment Fund Optimizing the properties of electromagnetic energy in a medium using stochastic parallel perturbation gradient descent optimization adaptive optics
US7775665B2 (en) * 2001-11-13 2010-08-17 Dellavecchia Michael A Method for optically scanning objects
US20040165147A1 (en) * 2001-11-13 2004-08-26 Della Vecchia Michael A. Determining iris biometric and spatial orientation of an iris in accordance with same
US6648473B2 (en) 2001-11-13 2003-11-18 Philadelphia Retina Endowment Fund High-resolution retina imaging and eye aberration diagnostics using stochastic parallel perturbation gradient descent optimization adaptive optics
US7377647B2 (en) * 2001-11-13 2008-05-27 Philadelphia Retina Endowment Fund Clarifying an image of an object to perform a procedure on the object
US7034949B2 (en) 2001-12-10 2006-04-25 Ophthonix, Inc. Systems and methods for wavefront measurement
US6781681B2 (en) 2001-12-10 2004-08-24 Ophthonix, Inc. System and method for wavefront measurement
US6739721B2 (en) 2001-12-11 2004-05-25 Bausch And Lomb, Inc Method and apparatus for calibrating and certifying accuracy of a wavefront sensing device
US20030107814A1 (en) * 2001-12-11 2003-06-12 Altmann Griffith E. Method and apparatus for improving the dynamic range and accuracy of a Shack-Hartmann wavefront sensor
US6755524B2 (en) * 2001-12-12 2004-06-29 Inray Ltd. Ophthalmic optical elements and methods for the design thereof
US6637884B2 (en) 2001-12-14 2003-10-28 Bausch & Lomb Incorporated Aberrometer calibration
US6736509B2 (en) 2001-12-21 2004-05-18 Bausch And Lomb, Inc. Aberrometer illumination apparatus and method
MXPA04006954A (es) 2002-01-17 2005-03-23 Perez Edward Metodos para producir colgajos epiteliales sobre la cornea y para la colocacion de dispositivos oculares y lentes debajo de un colgajo o membrana epitelial, dispositivo de deslaminacion epitelial, y estructuras de epitelio y dispositivos y lentes ocu
US20030142271A1 (en) 2002-01-30 2003-07-31 Ross Denwood F. Aberration and corneal topography measurement
US7115305B2 (en) 2002-02-01 2006-10-03 California Institute Of Technology Method of producing regular arrays of nano-scale objects using nano-structured block-copolymeric materials
JP4343699B2 (ja) * 2002-02-11 2009-10-14 ヴィズイクス・インコーポレーテッド 収差を伴なう水晶体を切削するための閉ループ・システムおよび方法
US7108691B2 (en) * 2002-02-12 2006-09-19 Visx, Inc. Flexible scanning beam imaging system
US6761454B2 (en) 2002-02-13 2004-07-13 Ophthonix, Inc. Apparatus and method for determining objective refraction using wavefront sensing
US20050174535A1 (en) * 2003-02-13 2005-08-11 Lai Shui T. Apparatus and method for determining subjective responses using objective characterization of vision based on wavefront sensing
JP3916482B2 (ja) * 2002-02-27 2007-05-16 株式会社ニデック 眼科装置
US20080106633A1 (en) * 2002-03-13 2008-05-08 Blum Ronald D Electro-optic lens with integrated components for varying refractive properties
US7130835B2 (en) 2002-03-28 2006-10-31 Bausch & Lomb Incorporated System and method for predictive ophthalmic correction
AU2003225276A1 (en) 2002-05-03 2003-11-17 University Of Rochester Sharpness metric for vision quality
US6663240B2 (en) 2002-05-15 2003-12-16 Alcon, Inc. Method of manufacturing customized intraocular lenses
EP1516156B1 (en) 2002-05-30 2019-10-23 AMO Manufacturing USA, LLC Tracking torsional eye orientation and position
AU2003273559A1 (en) 2002-05-31 2003-12-19 Carl Zeiss Meditec Ag Method for controlling a device for treating the human eye
AU2003245458A1 (en) 2002-06-12 2003-12-31 Advanced Research And Technology Institute, Inc. Method and apparatus for improving both lateral and axial resolution in ophthalmoscopy
US7083609B2 (en) * 2002-06-13 2006-08-01 Visx, Incorporated Corneal topography-based target warping
DE10227120A1 (de) * 2002-06-15 2004-03-04 Carl Zeiss Jena Gmbh Mikroskop, insbesondere Laserscanningmikroskop mit adaptiver optischer Einrichtung
US20040021826A1 (en) * 2002-08-01 2004-02-05 Sarver Edwin J. Combination advanced corneal topography/wave front aberration measurement
US7163292B2 (en) * 2002-09-06 2007-01-16 Synergeyes, Inc. Hybrid contact lens system and method
US7322694B2 (en) 2002-09-06 2008-01-29 Synergeyes, Inc. Hybrid contact lens system and method
US7104648B2 (en) * 2002-09-06 2006-09-12 Synergeyes, Inc. Hybrid contact lens system and method
AU2003263085A1 (en) * 2002-09-06 2004-03-29 Quarter Lambda Technologies, Inc. Hybrid contact lens system and method
AU2003266599A1 (en) * 2002-09-26 2004-04-19 Kabushiki Kaisha Topcon Eye characteristics measuring system
DE10245081A1 (de) * 2002-09-27 2004-04-01 Carl Zeiss Verfahren zur Bearbeitung eines Vorfabrikates oder eines Halbfabrikates
US7195354B2 (en) * 2002-10-04 2007-03-27 The Regents Of The University Of California Adaptive ophthalmologic system
EP1546791A1 (de) * 2002-10-04 2005-06-29 Carl Zeiss AG Verfahren zur herstellung einer linse und danach hergestellte linse
US6870659B2 (en) * 2002-10-11 2005-03-22 Exajoule, Llc Micromirror systems with side-supported mirrors and concealed flexure members
US6825968B2 (en) * 2002-10-11 2004-11-30 Exajoule, Llc Micromirror systems with electrodes configured for sequential mirror attraction
US6798560B2 (en) * 2002-10-11 2004-09-28 Exajoula, Llc Micromirror systems with open support structures
US7406263B2 (en) * 2002-10-17 2008-07-29 Aoptix Technologies Combined wavefront sensor and data detector for a free space optical communications system with adaptive optics
US7381221B2 (en) * 2002-11-08 2008-06-03 Advanced Medical Optics, Inc. Multi-zonal monofocal intraocular lens for correcting optical aberrations
US6887232B2 (en) * 2002-11-13 2005-05-03 20/10 Perfect Vision Optische Geraete Gmbh Closed loop control for intrastromal wavefront-guided ablation
US7232436B2 (en) * 2002-11-13 2007-06-19 Josef Bille Closed loop control for intrastromal wavefront-guided ablation with fractionated treatment program
US7209414B2 (en) * 2002-11-15 2007-04-24 Plasmon Lms, Inc Spherical aberration compensation by wavelength
ITTO20021007A1 (it) * 2002-11-19 2004-05-20 Franco Bartoli Apparecchiatura laser ad eccimeri e metodo di pilotaggio
US7407285B2 (en) 2002-11-20 2008-08-05 Ming Lai Method and apparatus for obtaining patient-verified prescription of high order aberrations
AU2002953061A0 (en) * 2002-11-20 2002-12-19 Sola International Holdings Ltd Method for designing progressive lenses
US7896916B2 (en) 2002-11-29 2011-03-01 Amo Groningen B.V. Multifocal ophthalmic lens
SE0203564D0 (sv) * 2002-11-29 2002-11-29 Pharmacia Groningen Bv Multifocal opthalmic lens
US7320517B2 (en) 2002-12-06 2008-01-22 Visx, Incorporated Compound modulation transfer function for laser surgery and other optical applications
US8911086B2 (en) 2002-12-06 2014-12-16 Amo Manufacturing Usa, Llc Compound modulation transfer function for laser surgery and other optical applications
US8342686B2 (en) 2002-12-06 2013-01-01 Amo Manufacturing Usa, Llc. Compound modulation transfer function for laser surgery and other optical applications
US7434936B2 (en) * 2002-12-06 2008-10-14 Amo Manufacturing Usa, Llc Residual accommodation threshold for correction of presbyopia and other presbyopia correction using patient data
US7293873B2 (en) * 2002-12-06 2007-11-13 Visx, Incorporated Presbyopia correction using patient data
US6939342B2 (en) * 2002-12-12 2005-09-06 Bausch And Lomb Incorporated System and method for evaluating a secondary LASIK treatment
US7289736B1 (en) 2003-01-13 2007-10-30 Aoptix Technologies Adaptive optics imaging system with object acquisition capability
US7286766B2 (en) 2003-01-16 2007-10-23 Aoptix Technologies, Inc. Free space optical communication system with power level management
US7036931B2 (en) * 2003-01-29 2006-05-02 Novartis Ag Ophthalmic lenses
US6736510B1 (en) 2003-02-04 2004-05-18 Ware Tec Vision Systems, Inc. Ophthalmic talbot-moire wavefront sensor
DE10306087B4 (de) 2003-02-07 2022-07-14 Carl Zeiss Meditec Ag Mikroskop, Verfahren zum Erhöhen der Bildqualität eines Mikroskops und Spiegelelement für ein Mikroskop
US6910770B2 (en) * 2003-02-10 2005-06-28 Visx, Incorporated Eye refractor with active mirror wavefront sensor
US7414712B2 (en) 2003-02-13 2008-08-19 University Of Rochester Large dynamic range Shack-Hartmann wavefront sensor
US20040227932A1 (en) * 2003-02-13 2004-11-18 Geunyoung Yoon Large dynamic range shack-hartmann wavefront sensor
US6906848B2 (en) * 2003-02-24 2005-06-14 Exajoule, Llc Micromirror systems with concealed multi-piece hinge structures
US6900922B2 (en) * 2003-02-24 2005-05-31 Exajoule, Llc Multi-tilt micromirror systems with concealed hinge structures
US6988801B2 (en) * 2003-03-25 2006-01-24 University Of Rochester Compact portable wavefront sensor
WO2004086952A2 (en) * 2003-03-28 2004-10-14 Digital Vision, Llc Application of neuro-ocular wavefront data in vision correction
US7556378B1 (en) 2003-04-10 2009-07-07 Tsontcho Ianchulev Intraoperative estimation of intraocular lens power
CA2522787C (en) * 2003-04-18 2012-09-18 Visx, Incorporated Systems and methods for correcting high order aberrations in laser refractive surgery
WO2004096014A2 (en) * 2003-04-28 2004-11-11 University Of Rochester Metrics to predict subjective impact of eye's wave aberration
US7387394B2 (en) 2003-04-30 2008-06-17 Topcon Corporation Deformable mirror control device and device for observing retina of eye
JP4121890B2 (ja) * 2003-04-30 2008-07-23 株式会社トプコン 眼底観察装置及び眼底観察方法
US7057806B2 (en) * 2003-05-09 2006-06-06 3M Innovative Properties Company Scanning laser microscope with wavefront sensor
US20040263779A1 (en) * 2003-06-12 2004-12-30 Visx, Inc. Hartmann-Shack wavefront measurement
US7458683B2 (en) * 2003-06-16 2008-12-02 Amo Manufacturing Usa, Llc Methods and devices for registering optical measurement datasets of an optical system
US7175278B2 (en) 2003-06-20 2007-02-13 Visx, Inc. Wavefront reconstruction using fourier transformation and direct integration
US7168807B2 (en) * 2003-06-20 2007-01-30 Visx, Incorporated Iterative fourier reconstruction for laser surgery and other optical applications
EP1648289B1 (en) * 2003-06-20 2013-06-12 AMO Manufacturing USA, LLC Systems and methods for prediction of objective visual acuity based on wavefront measurements
US8596787B2 (en) 2003-06-20 2013-12-03 Amo Manufacturing Usa, Llc Systems and methods for prediction of objective visual acuity based on wavefront measurements
DE10333558A1 (de) * 2003-07-23 2005-03-17 Technovision Gmbh Hornhautkeratoskopie beruhend auf einer Hornhaut- Wellenfrontmessung
DE10333813A1 (de) * 2003-07-24 2005-02-17 Technovision GmbH Gesellschaft für die Entwicklung medizinischer Technologie Online-Wellenfrontmessung und Anzeige
DE10333794A1 (de) * 2003-07-24 2005-03-03 Technovision Gmbh Verfahren und Vorrichtung zur Online-Kontaktlinsenbewertung
JP4330400B2 (ja) * 2003-08-04 2009-09-16 株式会社ニデック 眼科装置
EP1654566B1 (en) * 2003-08-15 2015-02-25 E-Vision LLC Enhanced electro-active lens system
DE10348854A1 (de) * 2003-10-20 2005-05-19 Lar Ip Ventures Inc. Verfahren und Vorrichtung zur Ermittlung der Restfehlsichtigkeit eines Patienten
US7226443B1 (en) 2003-11-07 2007-06-05 Alcon Refractivehorizons, Inc. Optimization of ablation correction of an optical system and associated methods
US7284862B1 (en) 2003-11-13 2007-10-23 Md Lasers & Instruments, Inc. Ophthalmic adaptive-optics device with a fast eye tracker and a slow deformable mirror
US7018039B2 (en) * 2003-11-14 2006-03-28 Synergeyes,Inc. Contact lens
US20080269731A1 (en) * 2003-11-19 2008-10-30 Casimir Andrew Swinger Method and apparatus applying patient-verified prescription of high order aberrations
US20050122473A1 (en) * 2003-11-24 2005-06-09 Curatu Eugene O. Method and apparatus for aberroscope calibration and discrete compensation
WO2005057252A2 (en) * 2003-12-02 2005-06-23 Wavetec Vision Systems, Inc. Interactive refractor incorporating wavefront sensing and adaptive optics
US7070276B2 (en) * 2003-12-04 2006-07-04 Rensselaer Polytechnic Institute Apparatus and method for accommodative stimulation of an eye and simultaneous ipsilateral accommodative imaging
PL1699345T3 (pl) * 2003-12-12 2013-10-31 Univ Indiana Res & Tech Corp System i sposób optymalizacji klinicznych zaleceń optycznych
DE10360570B4 (de) * 2003-12-22 2006-01-12 Carl Zeiss Optisches Meßsystem und optisches Meßverfahren
FR2865370B1 (fr) * 2004-01-22 2006-04-28 Centre Nat Rech Scient Systeme et procede de tomographie in vivo a haute resolution laterale et axiale de la retine humaine
FR2865371B1 (fr) * 2004-01-22 2007-12-21 Centre Nat Rech Scient Dispositif et procede de visee pour un examen de l'oeil, systeme d'examen de l'oeil par tomographie in vivo equipe de ce dispositif
JP2007519447A (ja) * 2004-02-02 2007-07-19 イアティア イメージング プロプライアタリー リミティド レンズ系の収差を矯正するための装置及び方法
US7343099B2 (en) * 2004-02-12 2008-03-11 Metrologic Instruments, Inc. Free space optical (FSO) laser communication system employing fade mitigation measures based on laser beam speckle tracking and locking principles
US7481536B2 (en) * 2004-02-19 2009-01-27 Amo Manufacturing Usa, Llc Methods and systems for differentiating left and right eye images
KR100900173B1 (ko) * 2004-02-20 2009-06-02 도오꾜오까고오교 가부시끼가이샤 패턴 형성 재료용 기재, 포지티브형 레지스트 조성물 및 레지스트 패턴 형성 방법
US7296893B2 (en) 2004-03-03 2007-11-20 Visx, Incorporated Transformation methods of wavefront maps from one vertex distance to another
CA2561388C (en) * 2004-04-20 2017-10-10 Wavetec Vision Systems, Inc. Integrated surgical microscope and wavefront sensor
US20050237485A1 (en) * 2004-04-21 2005-10-27 Blum Ronald D Method and apparatus for correcting vision
CN100430031C (zh) * 2004-04-26 2008-11-05 中国科学院光电技术研究所 双眼体视高阶像差矫正视觉仿真系统
JP2007536101A (ja) 2004-05-05 2007-12-13 カリフォルニア インスティテュート オブ テクノロジー ナノ繊維配列（ａｒｒａｙ）のキャピラリーリソグラフィー
US20050260388A1 (en) * 2004-05-21 2005-11-24 Lai Shui T Apparatus and method of fabricating an ophthalmic lens for wavefront correction using spatially localized curing of photo-polymerization materials
US7387387B2 (en) * 2004-06-17 2008-06-17 Amo Manufacturing Usa, Llc Correction of presbyopia using adaptive optics and associated methods
JP4510534B2 (ja) 2004-06-22 2010-07-28 株式会社トプコン 光学特性測定装置及び眼底像観察装置
US7708402B2 (en) * 2004-06-25 2010-05-04 Technion Research And Development Foundation Ltd. Goggles for improved ocular vision
US7465299B2 (en) * 2004-07-14 2008-12-16 Luigi Rovati Monitoring of retinal temperature during laser therapy
JP3946715B2 (ja) * 2004-07-28 2007-07-18 東京応化工業株式会社 ポジ型レジスト組成物およびレジストパターン形成方法
JP4609838B2 (ja) * 2004-08-10 2011-01-12 株式会社ニデック 角膜手術装置
US7377643B1 (en) * 2004-08-13 2008-05-27 Q Step Technologies, Inc. Method and apparatus for eye imaging with position registration and constant pupil size
US7360893B2 (en) * 2004-08-31 2008-04-22 20/10 Perfect Vision Optische Geraete Gmbh Systems and methods for shaping wavefronts in polychromatic light using phase shifting elements
JP2008512142A (ja) * 2004-09-03 2008-04-24 パナセカ， インコーポレイテッド ビジョンセンターキオスク
JP4468119B2 (ja) * 2004-09-08 2010-05-26 東京応化工業株式会社 レジスト組成物およびレジストパターン形成方法
US20060066808A1 (en) * 2004-09-27 2006-03-30 Blum Ronald D Ophthalmic lenses incorporating a diffractive element
US7922326B2 (en) * 2005-10-25 2011-04-12 Abbott Medical Optics Inc. Ophthalmic lens with multiple phase plates
EP2527908B1 (en) * 2004-10-25 2019-03-20 Johnson & Johnson Surgical Vision, Inc. Ophthalmic lens with multiple phase plates
JP4837323B2 (ja) * 2004-10-29 2011-12-14 東京応化工業株式会社 レジスト組成物、レジストパターン形成方法および化合物
US8021967B2 (en) 2004-11-01 2011-09-20 California Institute Of Technology Nanoscale wicking methods and devices
US9801709B2 (en) 2004-11-02 2017-10-31 E-Vision Smart Optics, Inc. Electro-active intraocular lenses
KR101244647B1 (ko) * 2004-11-02 2013-03-18 이-비젼 엘엘씨 전기 활성 안경 및 이의 제조 방법
US8915588B2 (en) 2004-11-02 2014-12-23 E-Vision Smart Optics, Inc. Eyewear including a heads up display
US8778022B2 (en) 2004-11-02 2014-07-15 E-Vision Smart Optics Inc. Electro-active intraocular lenses
SE0402769D0 (sv) 2004-11-12 2004-11-12 Amo Groningen Bv Method of selecting intraocular lenses
US8244342B2 (en) 2004-12-03 2012-08-14 The Invention Science Fund I, Llc Method and system for adaptive vision modification
US7334892B2 (en) 2004-12-03 2008-02-26 Searete Llc Method and system for vision enhancement
US7470027B2 (en) 2004-12-03 2008-12-30 Searete Llc Temporal vision modification
US7390088B2 (en) 2004-12-03 2008-06-24 Searete Llc Adjustable lens system with neural-based control
US7344244B2 (en) 2004-12-03 2008-03-18 Searete, Llc Adjustable lens system with neural-based control
US7656569B2 (en) 2004-12-03 2010-02-02 Searete Llc Vision modification with reflected image
US7350919B2 (en) 2004-12-03 2008-04-01 Searete Llc Vision modification with reflected image
US7334894B2 (en) * 2004-12-03 2008-02-26 Searete, Llc Temporal vision modification
US9155483B2 (en) 2004-12-03 2015-10-13 The Invention Science Fund I, Llc Vision modification with reflected image
US8104892B2 (en) 2004-12-03 2012-01-31 The Invention Science Fund I, Llc Vision modification with reflected image
US7486988B2 (en) 2004-12-03 2009-02-03 Searete Llc Method and system for adaptive vision modification
US7931373B2 (en) 2004-12-03 2011-04-26 The Invention Science Fund I, Llc Vision modification with reflected image
US7594727B2 (en) 2004-12-03 2009-09-29 Searete Llc Vision modification with reflected image
US7418115B2 (en) 2004-12-07 2008-08-26 Aoptix Technologies, Inc. Iris imaging using reflection from the eye
US7869627B2 (en) * 2004-12-07 2011-01-11 Aoptix Technologies, Inc. Post processing of iris images to increase image quality
WO2006063076A2 (en) * 2004-12-07 2006-06-15 Aoptix Technologies Iris imaging using reflection from the eye
US20060126019A1 (en) * 2004-12-10 2006-06-15 Junzhong Liang Methods and systems for wavefront analysis
US20060126018A1 (en) * 2004-12-10 2006-06-15 Junzhong Liang Methods and apparatus for wavefront sensing of human eyes
US8597282B2 (en) 2005-01-13 2013-12-03 Amo Manufacturing Usa, Llc Database system for centralized clinical and research applications with data from wavefront aberrometers
US8885139B2 (en) 2005-01-21 2014-11-11 Johnson & Johnson Vision Care Adaptive electro-active lens with variable focal length
DE102005005932A1 (de) * 2005-02-09 2006-08-17 Carl Zeiss Meditec Ag Fokussierung und Astigmatismuskompensator für eine Funduskamera
US20060217691A1 (en) * 2005-02-25 2006-09-28 Georg Schuele Real-time therapeutic dosimetry based on dynamic response of treated tissue
US8439502B2 (en) * 2005-03-09 2013-05-14 Advanced Vision Engineering, Inc Algorithms and methods for determining aberration-induced vision symptoms in the eye from wave aberration
DE102005013558A1 (de) * 2005-03-23 2006-09-28 Carl Zeiss Meditec Ag Verfahren und Vorrichtung zur Erhöhung der Tiefenschärfe eines optischen Systems
US7401922B2 (en) * 2005-04-13 2008-07-22 Synergeyes, Inc. Method and apparatus for reducing or eliminating the progression of myopia
AU2006235598A1 (en) * 2005-04-14 2006-10-19 University Of Rochester System and method for treating vision refractive errors
US20060235513A1 (en) * 2005-04-18 2006-10-19 Price Francis W Jr Corneal implants and methods of use
US7543936B2 (en) * 2005-05-06 2009-06-09 Synergeyes, Inc. Hybrid contact lens system and method of fitting
US20060264917A1 (en) * 2005-05-20 2006-11-23 Visx, Incorporated Scleral lenses for custom optic evaluation and visual performance improvement
US7441901B2 (en) * 2005-06-14 2008-10-28 Advanced Vision Engineering, Inc. Multitask vision architecture for refractive vision corrections
US7591556B2 (en) * 2005-06-24 2009-09-22 Boston Foundation For Sight Scleral contact lens with grooves and method of making lens
US7261412B2 (en) * 2005-06-30 2007-08-28 Visx, Incorporated Presbyopia correction through negative high-order spherical aberration
US20070019159A1 (en) * 2005-07-20 2007-01-25 Michiko Nakanishi Deforming method for deformable mirror, aberration compensation method for optical apparatus, aberration compensation method of ocular fundus observation apparatus, aberration compensation apparatus, optical apparatus and ocular funds observation apparatus
JP4947387B2 (ja) * 2005-08-18 2012-06-06 イマジン アイズ 眼科学機器に適用される眼の収差を補正する方法及びシステム
GB2429522A (en) * 2005-08-26 2007-02-28 Univ Kent Canterbury Optical mapping apparatus
US7331674B2 (en) * 2005-09-02 2008-02-19 Visx, Incorporated Calculating Zernike coefficients from Fourier coefficients
DE102005046130A1 (de) * 2005-09-27 2007-03-29 Bausch & Lomb Inc. System und Verfahren zur Behandlung eines Auges eines Patienten, das mit hoher Geschwindigkeit arbeitet
US7377637B2 (en) * 2005-10-11 2008-05-27 Synergeyes, Inc. Hybrid contact lens system and method of fitting
US8801781B2 (en) * 2005-10-26 2014-08-12 Abbott Medical Optics Inc. Intraocular lens for correcting corneal coma
EP1957099B1 (en) * 2005-11-07 2015-03-25 The Rockefeller University Reagents, methods and systems for selecting a cytotoxic antibody or variant thereof
DE102005053297A1 (de) * 2005-11-08 2007-05-10 Bausch & Lomb Inc. System und Verfahren zur Korrektur von ophthalmischen Brechungsfehlern
DE102005054691A1 (de) * 2005-11-16 2007-05-24 Bausch & Lomb Inc. Verfahren und Vorrichtung zur Bestimmung der Sehschärfe eines Auges
TWI262325B (en) * 2005-11-16 2006-09-21 Ind Tech Res Inst Eye aberration measurement and calibrating equipment and its method
WO2007073848A2 (de) 2005-12-15 2007-07-05 Franz Fankhauser Augenvermessungsvorrichtung mit hilfe dynamischer lichtstreuung
WO2007071401A1 (en) * 2005-12-21 2007-06-28 Novartis Ag Adaptive optic ophthalmic design system
US20070159562A1 (en) * 2006-01-10 2007-07-12 Haddock Joshua N Device and method for manufacturing an electro-active spectacle lens involving a mechanically flexible integration insert
US7520609B2 (en) * 2006-01-18 2009-04-21 Amo Manufacturing Llc Non-invasive measurement of tear volume systems and methods
US9101292B2 (en) 2006-01-20 2015-08-11 Clarity Medical Systems, Inc. Apparatus and method for operating a real time large dipoter range sequential wavefront sensor
US8100530B2 (en) 2006-01-20 2012-01-24 Clarity Medical Systems, Inc. Optimizing vision correction procedures
US9107608B2 (en) 2006-01-20 2015-08-18 Clarity Medical Systems, Inc. Apparatus and method for operating a real time large diopter range sequential wavefront sensor
US8820929B2 (en) 2006-01-20 2014-09-02 Clarity Medical Systems, Inc. Real-time measurement/display/record/playback of wavefront data for use in vision correction procedures
US8777413B2 (en) 2006-01-20 2014-07-15 Clarity Medical Systems, Inc. Ophthalmic wavefront sensor operating in parallel sampling and lock-in detection mode
US8356900B2 (en) 2006-01-20 2013-01-22 Clarity Medical Systems, Inc. Large diopter range real time sequential wavefront sensor
US7445335B2 (en) * 2006-01-20 2008-11-04 Clarity Medical Systems, Inc. Sequential wavefront sensor
EP2520220A1 (en) 2006-02-14 2012-11-07 Shui T. Lai Subjective refraction method and device for correcting low and higher order aberrations
US7726811B2 (en) 2006-02-14 2010-06-01 Lai Shui T Subjective wavefront refraction using continuously adjustable wave plates of Zernike function
US8474974B2 (en) 2006-02-24 2013-07-02 Amo Development Llc. Induced high order aberrations corresponding to geometrical transformations
US7717562B2 (en) * 2006-02-24 2010-05-18 Amo Development Llc. Scaling Zernike coefficients to smaller pupil sizes for refractive treatments
US7695136B2 (en) * 2007-08-01 2010-04-13 Amo Development, Llc. Wavefront refractions and high order aberration correction when wavefront maps involve geometrical transformations
US8454160B2 (en) 2006-02-24 2013-06-04 Amo Development, Llc Zone extension systems and methods
WO2007106657A2 (en) * 2006-03-14 2007-09-20 Amo Manufacturing Usa, Llc Spatial frequency wavefront sensor system and method
JP2007252402A (ja) * 2006-03-20 2007-10-04 Topcon Corp 眼科測定装置
CA2644545C (en) * 2006-03-23 2013-01-22 Amo Manufacturing Usa, Llc Systems and methods for wavefront reconstruction for aperture with arbitrary shape
US7758189B2 (en) * 2006-04-24 2010-07-20 Physical Sciences, Inc. Stabilized retinal imaging with adaptive optics
US8771261B2 (en) * 2006-04-28 2014-07-08 Topcon Medical Laser Systems, Inc. Dynamic optical surgical system utilizing a fixed relationship between target tissue visualization and beam delivery
CA2649065A1 (en) * 2006-05-01 2007-11-15 Physical Sciences, Inc. Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope
US7791734B2 (en) * 2006-05-02 2010-09-07 Lawrence Livermore National Security, Llc High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography
WO2007124602A1 (en) * 2006-05-03 2007-11-08 Campbell Melanie C W Method and device for delivering localized light energy to the eye
US20080273166A1 (en) 2007-05-04 2008-11-06 William Kokonaski Electronic eyeglass frame
WO2008088571A2 (en) * 2006-05-08 2008-07-24 Lai Shui T Subjective wavefront refraction using continuously adjustable wave plates of zernike function
WO2008105780A2 (en) 2006-05-24 2008-09-04 Pixeloptics, Inc. Optical rangefinder for an electro-active lens
US7537339B2 (en) * 2006-05-25 2009-05-26 Synergeyes, Inc. Hybrid contact lens system and method of fitting
SG172726A1 (en) * 2006-06-23 2011-07-28 Pixeloptics Inc Electronic adapter for electro-active spectacle lenses
US20080004698A1 (en) * 2006-06-30 2008-01-03 Alcon, Inc. Correction of surgically-induced astigmatism during intraocular lens implants
US9955867B2 (en) 2006-07-26 2018-05-01 Shui T. Lai Intrastromal surgery correcting low order and high order aberrations of the eye
DE102006036085A1 (de) 2006-08-02 2008-02-07 Bausch & Lomb Incorporated Verfahren und Vorrichtung zur Berechnung einer Laserschußdatei zur Verwendung in einem Excimer-Laser
DE102006036086A1 (de) * 2006-08-02 2008-02-07 Bausch & Lomb Incorporated Verfahren und Vorrichtung zur Berechnung einer Laserschußdatei zur Verwendung in einem refraktiven Excimer-Laser
WO2008036695A2 (en) * 2006-09-18 2008-03-27 Lai Shui T Customized contact lenses for reducing aberrations of the eye
US20080074611A1 (en) * 2006-09-22 2008-03-27 Meyers William E Hybrid contact lens with improved resistance to flexure and method for designing the same
US20080084541A1 (en) * 2006-10-06 2008-04-10 Ming Lai Ophthalmic system and method
US20090201460A1 (en) * 2006-10-27 2009-08-13 Blum Ronald D Spectacle temple for lens
WO2008077006A1 (en) * 2006-12-19 2008-06-26 Novartis Ag Premium vision ophthalmic lenses
DE102006061933A1 (de) * 2006-12-21 2008-06-26 Carl Zeiss Meditec Ag Optisches System für eine Funduskamera
WO2008083015A2 (en) * 2006-12-31 2008-07-10 Novartis Ag Method and system for determining power profile for an eye
US20110319875A1 (en) * 2007-01-19 2011-12-29 Frieder Loesel Apparatus and Method for Morphing a Three-Dimensional Target Surface into a Two-Dimensional Image for Use in Guiding a Laser Beam in Ocular Surgery
AR064985A1 (es) 2007-01-22 2009-05-06 E Vision Llc Lente electroactivo flexible
US8066769B2 (en) 2007-01-29 2011-11-29 Werblin Research & Development Corp. Intraocular lens system
US8066768B2 (en) 2007-01-29 2011-11-29 Werblin Research & Development Corp. Intraocular lens system
US7811320B2 (en) * 2007-01-29 2010-10-12 Werblin Research & Development Corp. Intraocular lens system
US9398949B2 (en) * 2007-01-29 2016-07-26 Emmetropia, Inc. Intraocular lens system
US7926940B2 (en) 2007-02-23 2011-04-19 Pixeloptics, Inc. Advanced electro-active optic device
EP2124713A1 (en) * 2007-02-23 2009-12-02 Mimo AG Ophthalmologic apparatus for imaging an eye by optical coherence tomography
AU2008218240B2 (en) 2007-02-23 2014-01-30 E-Vision Smart Optics, Inc. Ophthalmic dynamic aperture
CN101254091B (zh) * 2007-02-28 2010-08-18 深圳大学 一种视网膜成像的方法
US7883206B2 (en) 2007-03-07 2011-02-08 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US20080273169A1 (en) 2007-03-29 2008-11-06 Blum Ronald D Multifocal Lens Having a Progressive Optical Power Region and a Discontinuity
US20090091818A1 (en) * 2007-10-05 2009-04-09 Haddock Joshua N Electro-active insert
US7883207B2 (en) 2007-12-14 2011-02-08 Pixeloptics, Inc. Refractive-diffractive multifocal lens
TWI407971B (zh) * 2007-03-30 2013-09-11 Nitto Denko Corp Cancer cells and tumor-related fibroblasts
DE102007017611A1 (de) 2007-04-12 2008-10-16 SCHRÜNDER, Stephan Verfahren und System zur Augenvermessung
WO2008131479A1 (en) * 2007-04-27 2008-11-06 The Institute For Eye Research Limited Determination of optical adjustments for retarding myopia progression
US11061252B2 (en) 2007-05-04 2021-07-13 E-Vision, Llc Hinge for electronic spectacles
US10613355B2 (en) 2007-05-04 2020-04-07 E-Vision, Llc Moisture-resistant eye wear
US8016420B2 (en) 2007-05-17 2011-09-13 Amo Development Llc. System and method for illumination and fixation with ophthalmic diagnostic instruments
AU2008256709B2 (en) 2007-05-24 2012-09-20 Amo Development, Llc Accommodation compensation systems and methods
US7828432B2 (en) 2007-05-25 2010-11-09 Synergeyes, Inc. Hybrid contact lenses prepared with expansion controlled polymeric materials
WO2009003107A1 (en) * 2007-06-26 2008-12-31 Bausch & Lomb Incorporated Method for modifying the refractive index of ocular tissues
US7988290B2 (en) * 2007-06-27 2011-08-02 AMO Wavefront Sciences LLC. Systems and methods for measuring the shape and location of an object
US7976163B2 (en) 2007-06-27 2011-07-12 Amo Wavefront Sciences Llc System and method for measuring corneal topography
US8317321B2 (en) 2007-07-03 2012-11-27 Pixeloptics, Inc. Multifocal lens with a diffractive optical power region
US8550625B2 (en) 2007-08-01 2013-10-08 Amo Development, Llc Systems and methods for fine-tuning refractive surgery
WO2009024981A2 (en) 2007-08-21 2009-02-26 Visionix Ltd. Multifunctional ophthalmic measurement system
CN101772696A (zh) * 2007-08-27 2010-07-07 株式会社尼康 波面像差测量装置及方法、以及波面像差调整方法
US8974526B2 (en) 2007-08-27 2015-03-10 Amo Groningen B.V. Multizonal lens with extended depth of focus
EP2197400B1 (en) 2007-09-05 2014-12-31 Alcon LenSx, Inc. Laser-induced protection shield in laser surgery
US9456925B2 (en) 2007-09-06 2016-10-04 Alcon Lensx, Inc. Photodisruptive laser treatment of the crystalline lens
EP2826436B1 (en) 2007-09-06 2018-03-28 Alcon LenSx, Inc. Precise targeting of surgical photodisruption
US20100324543A1 (en) * 2007-09-18 2010-12-23 Kurtz Ronald M Method And Apparatus For Integrating Cataract Surgery With Glaucoma Or Astigmatism Surgery
US8333474B2 (en) 2007-10-19 2012-12-18 Wavetec Vision Systems, Inc. Optical instrument alignment system
US7594729B2 (en) 2007-10-31 2009-09-29 Wf Systems, Llc Wavefront sensor
US20100324542A1 (en) * 2007-11-02 2010-12-23 Kurtz Ronald M Method to Guide a Cataract Procedure by Corneal Imaging
US9395534B2 (en) * 2007-11-27 2016-07-19 Wisconsin Alumni Research Foundation Optical system for correction of tissue induced aberration
US7874674B2 (en) * 2007-12-12 2011-01-25 Allred Lloyd G Aberrometer having reduced noise
US7802883B2 (en) 2007-12-20 2010-09-28 Johnson & Johnson Vision Care, Inc. Cosmetic contact lenses having a sparkle effect
ES2757628T3 (es) 2008-01-09 2020-04-29 Alcon Inc Fragmentación de tejido curvada mediante láser fotodisruptivo
US8154804B2 (en) 2008-03-25 2012-04-10 E-Vision Smart Optics, Inc. Electro-optic lenses for correction of higher order aberrations
CA2725508C (en) * 2008-04-04 2019-02-26 Amo Regional Holdings Systems and methods for determining intraocular lens power
US8529558B2 (en) * 2008-04-22 2013-09-10 Amo Development Llc. High-order optical correction during corneal laser surgery
JP5306041B2 (ja) * 2008-05-08 2013-10-02 キヤノン株式会社 撮像装置及びその方法
DE102008026576A1 (de) * 2008-05-30 2009-12-03 Carl Zeiss Meditec Ag Optisches System für ophtalmologische Geräte, insbesondere Funduskameras
US8529557B2 (en) * 2008-05-30 2013-09-10 Technolas Perfect Vision Gmbh System and method for stray light compensation of corneal cuts
DE102008028509A1 (de) * 2008-06-16 2009-12-24 Technolas Gmbh Ophthalmologische Systeme Behandlungsmusterüberwachungsvorrichtung
KR101312706B1 (ko) 2008-06-30 2013-10-01 웨이브라이트 게엠베하 안과 레이저 수술, 특히 굴절교정 레이저 수술 장치
DE102008035995A1 (de) * 2008-08-01 2010-02-04 Technolas Perfect Vision Gmbh Kombination einer Excimer-Laserablation und Femtosekundenlasertechnik
KR101261715B1 (ko) * 2008-08-28 2013-05-09 테크놀러스 퍼펙트 비젼 게엠베하 눈 측정 및 모델링 기술
US8020994B2 (en) * 2008-09-04 2011-09-20 Heidelberg Engineering Gmbh Custom phase plate
US7988295B2 (en) * 2008-10-28 2011-08-02 Heidelberg Engineering Gmbh Laser control with phase plate feedback
DE102008053827A1 (de) 2008-10-30 2010-05-12 Technolas Perfect Vision Gmbh Vorrichtung und Verfahren zum Bereitstellen einer Laserschussdatei
US8254724B2 (en) * 2008-11-06 2012-08-28 Bausch & Lomb Incorporated Method and apparatus for making and processing aberration measurements
WO2010054268A2 (en) 2008-11-06 2010-05-14 Wavetec Vision Systems, Inc. Optical angular measurement system for ophthalmic applications and method for positioning of a toric intraocular lens with increased accuracy
US7695135B1 (en) 2008-11-11 2010-04-13 Boston Foundation For Sight Scleral lens with scalloped channels or circumferential fenestrated channels
US7980698B2 (en) 2008-11-19 2011-07-19 Bausch & Lomb Incorporated Power-adjusted aberrometer
WO2010065475A2 (en) 2008-12-01 2010-06-10 Junzhong Liang Methods and devices for refractive correction of eyes
US9277863B2 (en) 2008-12-01 2016-03-08 Perfect Vision Technology (Hk) Ltd. Methods and systems for automated measurement of the eyes and delivering of sunglasses and eyeglasses
US9649032B2 (en) 2008-12-01 2017-05-16 Perfect Vision Technology (Hk) Ltd. Systems and methods for remote measurement of the eyes and delivering of sunglasses and eyeglasses
US8201943B2 (en) * 2009-01-15 2012-06-19 Physical Sciences, Inc. Adaptive optics line scanning ophthalmoscope
US8979266B2 (en) * 2009-01-23 2015-03-17 Indiana University Research And Technology Corporation Devices and methods for polarization-sensitive optical coherence tomography and adaptive optics
EP2395953A4 (en) * 2009-02-12 2013-06-19 Univ Rochester ABERRATION CONTROL BY THE RETICULATION OF THE CORNEAL COLLAGEN COMBINED WITH THE BEAMFORMING TECHNIQUE
US8137271B2 (en) * 2009-03-04 2012-03-20 Heidelberg Engineering Gmbh System and method for assessing risk of glaucoma onset
ES2346392B1 (es) 2009-03-04 2011-10-03 Voptica, S.L. Metodo de medida y control binocular de las aberraciones de los ojos,presentacion simultanea de estimulos visuales, e instrumento oftalmico que implementa dicho metodo.
JP5676856B2 (ja) * 2009-05-08 2015-02-25 キヤノン株式会社 補償光学系を備えた画像取得装置
US8876290B2 (en) 2009-07-06 2014-11-04 Wavetec Vision Systems, Inc. Objective quality metric for ocular wavefront measurements
WO2011008609A1 (en) 2009-07-14 2011-01-20 Wavetec Vision Systems, Inc. Ophthalmic surgery measurement system
WO2011008606A1 (en) 2009-07-14 2011-01-20 Wavetec Vision Systems, Inc. Determination of the effective lens position of an intraocular lens using aphakic refractive power
WO2011016437A1 (ja) * 2009-08-04 2011-02-10 国立大学法人宇都宮大学 網膜用３次元画像生成装置
JP5553635B2 (ja) * 2009-10-23 2014-07-16 キヤノン株式会社 補償光学装置、撮像装置および補償光学方法、撮像方法
JP5483996B2 (ja) * 2009-10-23 2014-05-07 キヤノン株式会社 補償光学装置、撮像装置、補償光学方法
US9492322B2 (en) * 2009-11-16 2016-11-15 Alcon Lensx, Inc. Imaging surgical target tissue by nonlinear scanning
JP5511324B2 (ja) * 2009-11-17 2014-06-04 キヤノン株式会社 補償光学装置、補償光学方法、撮像装置、撮像方法
JP5511323B2 (ja) * 2009-11-17 2014-06-04 キヤノン株式会社 補償光学装置、補償光学方法、撮像装置、撮像方法
JP5517571B2 (ja) * 2009-11-18 2014-06-11 キヤノン株式会社 撮像装置および撮像方法
JP5596797B2 (ja) * 2010-01-21 2014-09-24 フィジカル サイエンシーズ， インコーポレイテッド 光学装置および眼の網膜を撮像する方法
US8265364B2 (en) 2010-02-05 2012-09-11 Alcon Lensx, Inc. Gradient search integrated with local imaging in laser surgical systems
CN102753085B (zh) 2010-02-12 2015-11-25 庄臣及庄臣视力保护公司 获得临床眼科高阶光学像差的装置
US8414564B2 (en) 2010-02-18 2013-04-09 Alcon Lensx, Inc. Optical coherence tomographic system for ophthalmic surgery
CN101840193B (zh) * 2010-03-25 2013-03-06 苏州大学 一种制作全息光栅的方法
US9642518B2 (en) 2010-03-30 2017-05-09 Amo Development, Llc Random eye generation systems and methods
US8409178B2 (en) 2010-03-30 2013-04-02 Amo Development Llc. Systems and methods for evaluating treatment tables for refractive surgery
JP5545984B2 (ja) * 2010-05-31 2014-07-09 株式会社ニデック 波面補償付眼底撮影装置
US8398236B2 (en) 2010-06-14 2013-03-19 Alcon Lensx, Inc. Image-guided docking for ophthalmic surgical systems
DE102010024606B4 (de) * 2010-06-22 2019-11-14 Carl Zeiss Meditec Ag Aberrometrisches Messsystem
CN101869466B (zh) * 2010-07-13 2012-07-18 苏州微清医疗器械有限公司 基于自适应光学技术的共焦扫描与光学相干层析成像仪
CN102028449B (zh) * 2010-08-16 2012-12-12 苏州六六视觉科技股份有限公司 可进行分层成像的人眼视网膜成像系统及方法
US9532708B2 (en) 2010-09-17 2017-01-03 Alcon Lensx, Inc. Electronically controlled fixation light for ophthalmic imaging systems
CA2811803A1 (en) 2010-09-20 2012-03-29 Amo Development Llc System and methods for mitigating changes in pupil size during laser refractive surgery to maintain ablation centration
US8439902B2 (en) * 2010-09-30 2013-05-14 Wavelight Gmbh Apparatus and method for processing material with focused electromagnetic radiation
US10783999B2 (en) 2010-10-05 2020-09-22 Amo Development, Llc Basis data evaluation systems and methods
US20120083776A1 (en) 2010-10-05 2012-04-05 Amo Development, Llc Annular and other ablation profiles for refractive surgery systems and methods
GB2485175A (en) * 2010-11-03 2012-05-09 Univ City Optical imaging system using incoherent light and interference fringes
JP5727197B2 (ja) * 2010-11-04 2015-06-03 株式会社ニデック 波面補償付眼底撮影装置
US8801178B2 (en) 2010-11-04 2014-08-12 Nidek Co., Ltd. Fundus photographing apparatus
EP3330776A1 (en) 2010-12-01 2018-06-06 AMO Groningen B.V. A multifocal lens having an optical add power progression, and a system and method of providing same
US9931200B2 (en) 2010-12-17 2018-04-03 Amo Groningen B.V. Ophthalmic devices, systems, and methods for optimizing peripheral vision
WO2012088424A1 (en) * 2010-12-23 2012-06-28 The Trustees Of Columbia University In The City Of New York Lensless retinal camera apparatus and method
US10583039B2 (en) 2010-12-30 2020-03-10 Amo Wavefront Sciences, Llc Method and system for eye measurements and cataract surgery planning using vector function derived from prior surgeries
US10500092B2 (en) 2010-12-30 2019-12-10 Amo Wavefront Sciences, Llc Treatment planning method and system for controlling laser refractive surgery
US10582846B2 (en) 2010-12-30 2020-03-10 Amo Wavefront Sciences, Llc Method and system for eye measurements and cataract surgery planning using vector function derived from prior surgeries
US10582847B2 (en) 2010-12-30 2020-03-10 Amo Wavefront Sciences, Llc Method and system for eye measurements and cataract surgery planning using vector function derived from prior surgeries
US9501621B2 (en) 2011-03-18 2016-11-22 Amo Development, Llc Treatment validation systems and methods
EP3170475B1 (en) * 2011-03-24 2018-10-31 Kowa Company Ltd. Intraocular lens
US9895058B2 (en) 2011-03-25 2018-02-20 Carl Zeiss Meditec Ag Heads-up vision analyzer
JP5220208B2 (ja) 2011-03-31 2013-06-26 キヤノン株式会社 制御装置、撮像制御方法、およびプログラム
US8459794B2 (en) 2011-05-02 2013-06-11 Alcon Lensx, Inc. Image-processor-controlled misalignment-reduction for ophthalmic systems
US9622913B2 (en) 2011-05-18 2017-04-18 Alcon Lensx, Inc. Imaging-controlled laser surgical system
US10813791B2 (en) 2011-06-02 2020-10-27 University Of Rochester Method for modifying the refractive index of ocular tissues and applications thereof
US9521949B2 (en) 2011-06-23 2016-12-20 Amo Development, Llc Ophthalmic range finding
CA3133258A1 (en) 2011-06-23 2012-12-27 Amo Development, Llc Ophthalmic range finding
US8978660B2 (en) 2011-07-21 2015-03-17 Amo Development, Llc Tilt compensation, measurement, and associated adjustment of refractive prescriptions during surgical and other treatments of the eye
RU2482525C2 (ru) * 2011-08-17 2013-05-20 Федеральное государственное бюджетное учреждение науки Специальная астрофизическая обсерватория Российской академии наук Механизм компенсатора наклонов волнового фронта
US8398238B1 (en) 2011-08-26 2013-03-19 Alcon Lensx, Inc. Imaging-based guidance system for ophthalmic docking using a location-orientation analysis
EP2570073A1 (en) 2011-09-02 2013-03-20 Nidek Co., Ltd. Fundus photographing apparatus with wavefront compensation
EP2596745B1 (en) * 2011-10-07 2019-06-19 Popovic, Zoran Reference calibration for an adaptive optics system
US10159565B2 (en) 2011-10-14 2018-12-25 Amo Groningen B.V. Apparatus, system and method to account for spherical aberration at the iris plane in the design of an intraocular lens
RU2502212C2 (ru) * 2011-11-25 2013-12-20 Виктор Ильич Бетчер Способ формирования изображения на дисплее цифрового устройства
WO2013082466A1 (en) 2011-11-30 2013-06-06 Amo Development, Llc. System and method for ophthalmic surface measurements based on sequential estimates
US9023016B2 (en) 2011-12-19 2015-05-05 Alcon Lensx, Inc. Image processor for intra-surgical optical coherence tomographic imaging of laser cataract procedures
US9066784B2 (en) 2011-12-19 2015-06-30 Alcon Lensx, Inc. Intra-surgical optical coherence tomographic imaging of cataract procedures
KR102276220B1 (ko) 2012-01-06 2021-07-13 이-비전 스마트 옵틱스, 아이엔씨. 안경류 도킹 스테이션 및 전자 모듈
EP2819626A1 (en) 2012-02-22 2015-01-07 AMO Development, LLC Preformed lens systems and methods
CN102589720B (zh) * 2012-03-19 2014-01-01 中国科学院光电技术研究所 一种适用于非均匀光照明的哈特曼波前测量仪
TWI588560B (zh) * 2012-04-05 2017-06-21 布萊恩荷登視覺協會 用於屈光不正之鏡片、裝置、方法及系統
KR101648974B1 (ko) 2012-04-30 2016-08-17 클레러티 메디칼 시스템즈 인코포레이티드 병렬 샘플링 및 로크인 탐지 모드에서 동작하는 안과 웨이브프론트 센서
JP6041540B2 (ja) * 2012-06-01 2016-12-07 キヤノン株式会社 眼科装置
WO2014014805A1 (en) * 2012-07-16 2014-01-23 Trustees Of Boston University Solid immersion microscopy system with deformable mirror for correction of aberrations
WO2014015234A2 (en) 2012-07-20 2014-01-23 Amo Manufacturing Usa, Llc. Systems and methods for correcting high order aberrations in laser refractive surgery
KR101817289B1 (ko) * 2012-08-24 2018-01-10 어드밴스드 마이크로 디바이시즈, 인코포레이티드 광 아이솔레이터를 포함하는 레이저 스캔 모듈
BR112015004617A2 (pt) 2012-08-31 2017-07-04 Amo Groningen Bv sistemas e métodos para profundidade de foco estendida de lente de múltiplos áneis
US9072462B2 (en) 2012-09-27 2015-07-07 Wavetec Vision Systems, Inc. Geometric optical power measurement device
EP2903576A1 (en) 2012-10-02 2015-08-12 AMO Development, LLC Systems and methods for treatment target deconvolution
US9201250B2 (en) 2012-10-17 2015-12-01 Brien Holden Vision Institute Lenses, devices, methods and systems for refractive error
CN102860816B (zh) * 2012-10-12 2014-10-29 中国科学院光电技术研究所 一种基于双波前校正器的人眼视网膜三维成像装置
CN104768499B (zh) 2012-10-17 2017-06-23 华柏恩视觉研究中心 用于屈光不正的镜片、装置、方法和系统
CA2875873C (en) 2013-03-11 2022-06-21 Abbott Medical Optics Inc. Intraocular lens that matches an image surface to a retinal shape, and method of designing same
US9198573B2 (en) 2013-03-15 2015-12-01 Amo Wavefront Sciences, Llc Angular multiplexed optical coherence tomography systems and methods
EP2967325A4 (en) 2013-03-15 2017-03-08 NeuroVision Imaging LLC System and method for rejecting afocal light collected from an in vivo human retina
CN103385691B (zh) * 2013-08-02 2015-07-15 中国科学院光电技术研究所 双眼自适应光学视觉仿真器和仿真方法
CN103393400A (zh) * 2013-08-06 2013-11-20 中国科学院光电技术研究所 一种扫描式活体人眼视网膜高分辨力成像系统
US9357912B2 (en) 2013-09-09 2016-06-07 Yan Zhang Apparatus and method for characterizing biomechanical properties of eye tissue
AU2014346484A1 (en) 2013-11-07 2016-01-07 Amo Development Llc Treatment validation systems and methods
CA2935733A1 (en) 2013-12-31 2015-07-09 Amo Development, Llc. Wavefront measurement pre-smoothing systems and methods
EP3116442A1 (en) 2014-03-10 2017-01-18 Amo Groningen B.V. Intraocular lens that improves overall vision where there is a local loss of retinal function
CA2946356C (en) 2014-04-21 2022-09-20 Amo Groningen B.V. Ophthalmic devices, system and methods that improve peripheral vision
WO2016004385A1 (en) 2014-07-02 2016-01-07 IDx, LLC Systems and methods for alignment of the eye for ocular imaging
US10952606B2 (en) 2014-07-02 2021-03-23 Amo Development, Llc Optical measurement system and method including blink rate monitor and/or tear film breakup detector
EP3164054B1 (en) 2014-07-02 2019-12-25 AMO WaveFront Sciences, LLC Optical measurement system and method including blink rate monitor and/or tear film breakup detector
CA2953263A1 (en) 2014-07-03 2016-01-07 Amo Wavefront Sciences, Llc Optical measurement system and method with target brightness level adjustment
US20160038277A1 (en) 2014-08-11 2016-02-11 Amo Development, Llc Optical Surface Systems and Methods for Treatment of Presbyopia and Other Vision Conditions
DE102014112199A1 (de) 2014-08-26 2016-03-03 Carl Zeiss Microscopy Gmbh Mikroskopisches Abbildungssystem
JP6442960B2 (ja) 2014-09-30 2018-12-26 株式会社ニデック 波面補償付眼底撮影装置
WO2016111851A1 (en) 2015-01-09 2016-07-14 Amo Development, Llc Vergence weighting systems and methods for treatment of presbyopia and other vision conditions
AU2015381755A1 (en) 2015-02-06 2017-08-24 Amo Wavefront Sciences, Llc. Systems and methods of optical coherence tomography with a multi-focal delay line
JP6608153B2 (ja) * 2015-03-30 2019-11-20 蛇の目ミシン工業株式会社 サーボプレス、制御方法およびプログラム
CN104783755A (zh) * 2015-04-29 2015-07-22 中国科学院光电技术研究所 自适应光学视网膜成像装置和方法
KR101716125B1 (ko) * 2015-07-20 2017-03-15 주식회사 토모큐브 파면 제어기를 활용한 초고속 고정밀 3차원 굴절률 측정 방법 및 장치
AU2015404164A1 (en) 2015-07-27 2018-01-18 Amo Wavefront Sciences, Llc Optical imaging and measurement systems and methods for cataract surgery and treatment planning
CA3000417A1 (en) 2015-10-01 2017-04-06 Amo Wavefront Sciences, Llc Optical measurement systems and methods with custom chromatic aberration adjustments
US10820794B2 (en) 2015-11-06 2020-11-03 Canon Kabushiki Kaisha Pupil monitoring method for adaptive optics imaging system
CA3005955A1 (en) 2015-11-23 2017-06-01 Amo Wavefront Sciences, Llc Method and system for eye measurements and cataract surgery planning using vector function derived from prior surgeries
AU2017218681B2 (en) 2016-02-09 2021-09-23 Amo Groningen B.V. Progressive power intraocular lens, and methods of use and manufacture
EP3426191A1 (en) 2016-03-11 2019-01-16 Amo Groningen B.V. Intraocular lenses that improve peripheral vision
US10599006B2 (en) 2016-04-12 2020-03-24 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges
ES2861520T3 (es) 2016-04-12 2021-10-06 E Vision Smart Optics Inc Lentes electroactivas con puentes resistivos elevados
DE102016106953A1 (de) 2016-04-14 2017-10-19 Arnold & Richter Cine Technik Gmbh & Co. Betriebs Kg Kamerasucher
US11096778B2 (en) 2016-04-19 2021-08-24 Amo Groningen B.V. Ophthalmic devices, system and methods that improve peripheral vision
US10444539B2 (en) 2016-05-11 2019-10-15 Perect Vision Technology (Hk) Ltd. Methods and systems for determining refractive corrections of human eyes for eyeglasses
EP3471595A4 (en) * 2016-06-16 2019-07-17 Hadasit Medical Research Services and Development Ltd. DEVICE AND METHOD FOR DETERMINING THE PUPIL SIZE IN A PERSON WITH CLOSED EYELIDERS
EP4338717A2 (en) 2016-07-07 2024-03-20 AMO Development, LLC Lenticular laser incision using wavefront guided maps
US10327952B2 (en) 2016-08-31 2019-06-25 Amo Development, Llc Ultraviolet radiation sensor systems and methods for laser pulse energy control in eye surgery
AU2017324944B2 (en) 2016-09-06 2022-04-07 Amo Development, Llc Optical measurement systems and processes with wavefront aberrometer having variable focal length lens
WO2018049230A1 (en) 2016-09-08 2018-03-15 Amo Development, Llc Systems and methods for obtaining iris registration and pupil centration for laser surgery
US10555669B2 (en) 2016-11-09 2020-02-11 Amo Wavefront Sciences, Llc Optical coherence tomography systems and methods with dispersion compensation
WO2018102624A1 (en) 2016-12-01 2018-06-07 Amo Development, Llc Spherical aberration reduction systems and methods
US10060872B1 (en) 2017-02-13 2018-08-28 General Electric Company Sensing system and method
US20180235809A1 (en) 2017-02-22 2018-08-23 Amo Development Llc Transition zone systems and methods
US10849493B2 (en) 2017-02-28 2020-12-01 Amo Development, Llc Method and system for pupil retro illumination using sample arm of OCT interferometer
JP2020512079A (ja) * 2017-03-15 2020-04-23 クイーンズランド ユニバーシティ オブ テクノロジー 眼用レンズ設計の影響を測定する装置、方法、及びシステム
CA3056707A1 (en) 2017-03-17 2018-09-20 Amo Groningen B.V. Diffractive intraocular lenses for extended range of vision
US11523897B2 (en) 2017-06-23 2022-12-13 Amo Groningen B.V. Intraocular lenses for presbyopia treatment
WO2019002384A1 (en) 2017-06-28 2019-01-03 Amo Groningen B.V. DIFFRACTIVE LENSES AND INTRAOCULAR LENSES ASSOCIATED WITH THE TREATMENT OF PRESBYOPIA
CA3068351A1 (en) 2017-06-28 2019-01-03 Amo Groningen B.V. Extended range and related intraocular lenses for presbyopia treatment
US11327210B2 (en) 2017-06-30 2022-05-10 Amo Groningen B.V. Non-repeating echelettes and related intraocular lenses for presbyopia treatment
CA3075211A1 (en) 2017-09-11 2019-03-14 Amo Groningen B.V. Intraocular lenses with customized add power
US10973685B2 (en) 2017-12-01 2021-04-13 Amo Development, Llc Systems and methods for reducing spherical aberration using periphery modification
EP3743679B1 (en) 2018-01-23 2023-06-28 AMO Development, LLC Methods and systems of optical coherence tomography with fiducial signal for correcting scanning laser nonlinearity
WO2019194851A1 (en) * 2018-04-06 2019-10-10 Perfect Vision Technology (Hk) Ltd. Methods and systems of refraction automation for prescribing eyeglasses
EP3773145A1 (en) 2018-04-06 2021-02-17 AMO Development LLC Methods and systems for corneal topography with in-focus scleral imaging
US11246484B2 (en) 2018-08-20 2022-02-15 Amo Development, Llc Methods and systems for eye measurement with in-focus iris and scleral imaging
US11006823B2 (en) 2019-01-28 2021-05-18 Amo Development, Llc Methods and systems for optical coherence tomography scanning of cornea and retina
DE102019115931A1 (de) * 2019-06-12 2020-12-17 Carl Zeiss Microscopy Gmbh Optische Anordnung für ein Mikroskop
US11266495B2 (en) 2019-10-20 2022-03-08 Rxsight, Inc. Light adjustable intraocular lens with a modulable absorption front protection layer
EP4076134A1 (en) 2019-12-20 2022-10-26 AMO Development, LLC Optical measurement systems and processes with non-telecentric projection of fixation target to eye
EP4081093A1 (en) 2019-12-23 2022-11-02 AMO Development, LLC Optical measurement systems and processes with fixation target having cylinder compensation
CA3166308A1 (en) 2019-12-30 2021-07-08 Amo Groningen B.V. Lenses having diffractive profiles with irregular width for vision treatment
US11886046B2 (en) 2019-12-30 2024-01-30 Amo Groningen B.V. Multi-region refractive lenses for vision treatment
EP4084669A1 (en) 2019-12-30 2022-11-09 AMO Development, LLC Optical measurement systems and processes with fixation target having bokeh compensation
US20220322933A1 (en) 2021-04-13 2022-10-13 Amo Development, Llc Methods and systems for determining change in eye position between successive eye measurements
US20220330813A1 (en) 2021-04-15 2022-10-20 Amo Development, Llc Methods and systems for thickness measurements using spectrally resolved full gradient topography
US20220338731A1 (en) 2021-04-21 2022-10-27 Amo Development, Llc Compact autocylinder compensation module for autorefractor and autorefractor with autocylinder compensation module

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5838839A (ja) * 1981-08-31 1983-03-07 Tokyo Optical Co Ltd 屈折率測定装置
DE3150124C2 (de) * 1981-12-18 1985-01-31 Fa. Carl Zeiss, 7920 Heidenheim Vorrichtung zur Untersuchung der vorderen Augenabschnitte
DE3422144A1 (de) * 1984-06-14 1985-12-19 Josef Prof. Dr. 6900 Heidelberg Bille Geraet zur darstellung flaechenhafter bereiche des menschlichen auges
US4669466A (en) * 1985-01-16 1987-06-02 Lri L.P. Method and apparatus for analysis and correction of abnormal refractive errors of the eye
DE3607721A1 (de) 1986-03-08 1987-09-10 Rodenstock Instr Vorrichtung zur laserbehandlung des auges
US6267756B1 (en) * 1986-03-08 2001-07-31 G. Rodenstock Instrumente Gmbh Apparatus for the observation and the treatment of the eye using a laser
EP0259398B1 (de) * 1986-03-08 1992-01-15 G. Rodenstock Instrumente Gmbh Vorrichtung zur beobachtung und laserbehandlung des auges
US5177511A (en) * 1986-11-08 1993-01-05 G. Rodenstock Instruments Gmbh Apparatus for producing images of an object and in particular for observing the rear portions of the eye
US4764930A (en) * 1988-01-27 1988-08-16 Intelligent Surgical Lasers Multiwavelength laser source
US4848340A (en) * 1988-02-10 1989-07-18 Intelligent Surgical Lasers Eyetracker and method of use
US4881808A (en) * 1988-02-10 1989-11-21 Intelligent Surgical Lasers Imaging system for surgical lasers
IT1215851B (it) 1988-02-11 1990-02-22 Renato Liffredo Lente intraoculare con correzione cromatica e del diagramma di assorbimento.
US5011276A (en) * 1988-06-27 1991-04-30 Ryusyo Industrial Co., Ltd. Apparatus for measuring refractive power of eye
DE3821973A1 (de) * 1988-06-29 1990-02-08 Rodenstock Instr Vorrichtung zur erzeugung eines bildes eines objekts (iii)
US5098426A (en) * 1989-02-06 1992-03-24 Phoenix Laser Systems, Inc. Method and apparatus for precision laser surgery
US4991953A (en) * 1989-02-09 1991-02-12 Eye Research Institute Of Retina Foundation Scanning laser vitreous camera
US5159361A (en) * 1989-03-09 1992-10-27 Par Technology Corporation Method and apparatus for obtaining the topography of an object
JP2931325B2 (ja) * 1989-06-29 1999-08-09 興和株式会社 眼科測定装置
US4991653A (en) * 1989-11-08 1991-02-12 Halliburton Company Wash tool
DE4002029A1 (de) * 1990-01-24 1991-07-25 Peter Hoefer Verfahren zur herstellung von kontaktlinsen und kontaktlinsenfertigungssystem
JP2854657B2 (ja) * 1990-03-14 1999-02-03 興和株式会社 眼科測定装置
US5062702A (en) * 1990-03-16 1991-11-05 Intelligent Surgical Lasers, Inc. Device for mapping corneal topography
EP0466533B1 (fr) * 1990-06-27 1995-03-15 Framatome Procédé et dispositif de démantèlement d'un composant irradié d'un réacteur nucléaire par découpage de sa paroi
US5490849A (en) * 1990-07-13 1996-02-13 Smith; Robert F. Uniform-radiation caustic surface for photoablation
WO1992001417A1 (en) * 1990-07-19 1992-02-06 Horwitz Larry S Vision measurement and correction
AT395523B (de) * 1990-07-24 1993-01-25 Spellitz Fritz Optisches messsystem fuer die menschliche hornhaut
US5258791A (en) * 1990-07-24 1993-11-02 General Electric Company Spatially resolved objective autorefractometer
US5722427A (en) * 1993-05-10 1998-03-03 Eyesys Technologies, Inc. Method of refractive surgery
US5173723A (en) * 1990-10-02 1992-12-22 Volk Donald A Aspheric ophthalmic accommodating lens design for intraocular lens and contact lens
US5139022A (en) * 1990-10-26 1992-08-18 Philip Lempert Method and apparatus for imaging and analysis of ocular tissue
US5072993A (en) * 1990-12-24 1991-12-17 Caterpillar Inc. Self-contained shim pack assembly
US5214456A (en) * 1991-10-09 1993-05-25 Computed Anatomy Incorporated Mapping of corneal topography with display of pupil perimeter
JP3112108B2 (ja) * 1991-11-26 2000-11-27 株式会社トプコン 角膜厚さ測定装置
US5229889A (en) * 1991-12-10 1993-07-20 Hughes Aircraft Company Simple adaptive optical system
JPH0559448U (ja) * 1992-01-14 1993-08-06 松原電機工業株式会社 ディスプレイ装置
US5233174A (en) * 1992-03-11 1993-08-03 Hughes Danbury Optical Systems, Inc. Wavefront sensor having a lenslet array as a null corrector
US5241265A (en) 1992-03-26 1993-08-31 Northern Telecom Limited Logic function circuit with an array of data stores and their circuit testing
US5473392A (en) * 1992-05-01 1995-12-05 Summit Technology, Inc. Method and system for topographic measurement
US5841511A (en) * 1992-06-02 1998-11-24 Eyesys Technologies, Inc. Method of corneal analysis using a checkered placido apparatus
DE4222395A1 (de) * 1992-07-08 1994-01-13 Amtech Ges Fuer Angewandte Mic Vorrichtung und Verfahren zur Messung der Augenrefraktion
US5549632A (en) * 1992-10-26 1996-08-27 Novatec Laser Systems, Inc. Method and apparatus for ophthalmic surgery
US5307097A (en) 1992-11-05 1994-04-26 Kera-Metrics, Inc. Corneal topography system including single-direction shearing of holograph grating in orthogonal directions
JPH06171032A (ja) 1992-12-08 1994-06-21 Teijin Ltd パラグライダー用積層体
US5418714A (en) 1993-04-08 1995-05-23 Eyesys Laboratories, Inc. Method and apparatus for variable block size interpolative coding of images
US5293871A (en) * 1993-05-05 1994-03-15 Cornell Research Foundation Inc. System for ultrasonically determining corneal layer thicknesses and shape
US5452031A (en) * 1993-05-05 1995-09-19 Boston Eye Technology, Inc. Contact lens and a method for manufacturing contact lens
JP3305410B2 (ja) * 1993-05-18 2002-07-22 株式会社トプコン 眼科装置
EP0628281B1 (en) * 1993-06-10 1998-12-02 Konan Common Co., Ltd. Method for obtaining images of a cornea and apparatus for same
AU716040B2 (en) * 1993-06-24 2000-02-17 Bausch & Lomb Incorporated Ophthalmic pachymeter and method of making ophthalmic determinations
US5474548A (en) * 1993-07-14 1995-12-12 Knopp; Carl F. Method of establishing a unique machine independent reference frame for the eye
US5502518A (en) * 1993-09-09 1996-03-26 Scient Optics Inc Asymmetric aspheric contact lens
DE69402281T2 (de) * 1993-09-17 1997-09-04 Essilor Int Verfahren und Gerät zur absoluten Messung der geometrischen oder optischen Struktur eines optischen Bestandteiles
GB9323065D0 (en) 1993-11-09 1994-01-05 Besca Ltd A wide field retinal scanning ophthalmoscope
US5475452A (en) * 1994-02-24 1995-12-12 Keravision, Inc. Device and method for mapping objects
US5980513A (en) * 1994-04-25 1999-11-09 Autonomous Technologies Corp. Laser beam delivery and eye tracking system
US5632742A (en) * 1994-04-25 1997-05-27 Autonomous Technologies Corp. Eye movement sensing method and system
US5442412A (en) * 1994-04-25 1995-08-15 Autonomous Technologies Corp. Patient responsive eye fixation target method and system
US5861955A (en) * 1994-04-25 1999-01-19 Medjet Inc. Topographical cornea mapping for corneal vision correction
US5493391A (en) * 1994-07-11 1996-02-20 Sandia Corporation One dimensional wavefront distortion sensor comprising a lens array system
US5491524A (en) * 1994-10-05 1996-02-13 Carl Zeiss, Inc. Optical coherence tomography corneal mapping apparatus
WO1996013199A2 (en) * 1994-10-28 1996-05-09 Eyesys Technologies, Inc. Multi-camera corneal analysis system
US5528791A (en) 1995-06-23 1996-06-25 New Knight Inc. Wringer floor mop with pivoting head
US5629765A (en) * 1995-12-15 1997-05-13 Adaptive Optics Associates, Inc. Wavefront measuring system with integral geometric reference (IGR)
US5784146A (en) * 1995-12-28 1998-07-21 Nidek Co., Ltd Ophthalmic measurement apparatus
US6241355B1 (en) * 1996-03-29 2001-06-05 Brian A. Barsky Computer aided contact lens design and fabrication using spline surfaces
US5785704A (en) * 1996-07-29 1998-07-28 Mrc Systems Gmbh Method for performing stereotactic laser surgery
US5822035A (en) * 1996-08-30 1998-10-13 Heidelberg Engineering Optische Messysteme Gmbh Ellipsometer
US5735283A (en) * 1996-10-09 1998-04-07 Snook; Richard Kieth Surgical keratometer system for measuring surface topography of a cornea during surgery
US6271914B1 (en) 1996-11-25 2001-08-07 Autonomous Technologies Corporation Objective measurement and correction of optical systems using wavefront analysis
US20010041884A1 (en) 1996-11-25 2001-11-15 Frey Rudolph W. Method for determining and correcting vision
US5777719A (en) * 1996-12-23 1998-07-07 University Of Rochester Method and apparatus for improving vision and the resolution of retinal images
US5740803A (en) * 1997-03-07 1998-04-21 Autonomous Technologies Corporation Locating the center of the entrance pupil of an eye after pupil dilation
US6007204A (en) * 1998-06-03 1999-12-28 Welch Allyn, Inc. Compact ocular measuring system
US6002484A (en) * 1999-06-18 1999-12-14 Rozema; Jos J. Phase contrast aberroscope
US6439720B1 (en) * 2000-01-27 2002-08-27 Aoptics, Inc. Method and apparatus for measuring optical aberrations of the human eye

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100337581C (zh) * 2000-10-02 2007-09-19 庄臣及庄臣视力保护公司 测量波前像差的方法和设备
CN100333685C (zh) * 2000-10-10 2007-08-29 罗切斯特大学 根据波前象差数据确定眼睛折光度
CN100353907C (zh) * 2001-04-18 2007-12-12 博士伦公司 获得客观式显然验光的装置
CN100374833C (zh) * 2001-05-08 2008-03-12 庄臣及庄臣视力保护公司 用于测量波阵面像差的方法和装置
CN100449349C (zh) * 2005-04-20 2009-01-07 中国人民解放军国防科学技术大学 大口径线阵哈特曼波前传感器
CN101292862B (zh) * 2007-04-25 2012-02-29 江阴龙跃信息科技有限公司 视网膜细胞显微成像系统
CN103003747B (zh) * 2010-05-06 2016-08-31 赫克斯冈技术中心 尤其用于从飞行器拍摄航空图像的摄像机
CN103003747A (zh) * 2010-05-06 2013-03-27 赫克斯冈技术中心 尤其用于从飞行器拍摄航空图像的摄像机
US8955970B2 (en) 2010-12-20 2015-02-17 Canon Kabushiki Kaisha Fundus imaging method, fundus imaging apparatus, and storage medium
CN102551660B (zh) * 2010-12-20 2015-08-05 佳能株式会社 眼底摄像方法和眼底摄像设备
CN102551660A (zh) * 2010-12-20 2012-07-11 佳能株式会社 眼底摄像方法和眼底摄像设备
CN103876706A (zh) * 2012-12-21 2014-06-25 光电子有限公司 检眼镜中的改进以及与检眼镜相关的改进
CN103876706B (zh) * 2012-12-21 2017-04-12 光电子有限公司 检眼镜中的改进以及与检眼镜相关的改进
CN103431837A (zh) * 2013-08-23 2013-12-11 饶丰 基于哈特曼传感器的人眼轴向色差和横向色差测量装置及其方法
CN111936095A (zh) * 2018-01-26 2020-11-13 罗切斯特大学 折射率整形激光写入过程控制
CN111936095B (zh) * 2018-01-26 2023-09-01 罗切斯特大学 折射率整形激光写入过程控制

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