CN1889936A - 涂抹在皮肤上的制品的计量装置 - Google Patents

涂抹在皮肤上的制品的计量装置 Download PDF

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Publication number
CN1889936A
CN1889936A CNA2004800364515A CN200480036451A CN1889936A CN 1889936 A CN1889936 A CN 1889936A CN A2004800364515 A CNA2004800364515 A CN A2004800364515A CN 200480036451 A CN200480036451 A CN 200480036451A CN 1889936 A CN1889936 A CN 1889936A
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medicine
splendid attire
mentioned arbitrary
described device
silkis
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S·内格里耶
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Galdema AG
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Galderma Research and Development SNC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D34/00—Containers or accessories specially adapted for handling liquid toiletry or cosmetic substances, e.g. perfumes
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D40/00—Casings or accessories specially adapted for storing or handling solid or pasty toiletry or cosmetic substances, e.g. shaving soaps or lipsticks
    • A45D40/26—Appliances specially adapted for applying pasty paint, e.g. using roller, using a ball
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Abstract

本发明涉及一种计量涂抹在皮肤上的制品、特别是药物和化妆品的装置。本发明特别涉及一种小尺状装置，其刻度使得使用者能精确确定涂抹在皮肤上随治疗表面而变的药物的数量。

Description

涂抹在皮肤上的制品的计量装置
本发明涉及涂抹制品如药物的计量领域。本发明旨在提供一种计量涂抹在皮肤上的制品、特别是药物和化妆品的新装置。本发明特别涉及一种小尺形式的装置，其刻度使得使用者能确定涂抹在皮肤上随治疗表面积而变的药物的精确数量。
关于涂抹在皮肤上的药物，众所周知，局部涂抹的药效决定于其剂量。不管是制成乳膏、油膏、泡沫、液状还是膏药，从局部涂抹药物的包装装置是无法获得最佳计量的。因此当局部涂抹药物盛装在管子或简单瓶子中时，使用者无法计量所述药物精确涂抹剂量。
但有多种计量分配器。某些分配器为要求使用者手动抽吸的虹吸管状装置；它们往往包括许多部件，因此制造成本高。其它计量分配器上装有活塞型装置，但由于所供应制品的数量随使用者施加的压力而变，因此这类分配器不可靠。
此外这些计量分配器上的系统只能供应一次剂量的制品。
为克服上述缺点，本申请人研制出一种计量涂抹在皮肤上的药物的最佳装置，其中，所涂抹药物的数量精确且能根据所治疗皮肤的表面调节，从而提高治疗效果。
该目的由一种计量涂抹在皮肤上的制品、特别是药物或化妆品的装置实现，包括其上有一纵向凹槽的一小尺，沿该纵向凹槽有一系列室，所述凹槽中的药物数量与待治疗的皮肤的一定表面积对应，该数量由一个或多个室界定。
该小尺上有刻度，从凹槽的与第一室开端对应的一端到随后各室的这些刻度界定该凹槽各室中的药物数量。
按照一种特别实施方法，本发明装置包括至少两个、最好至少三个、更好四个室。
所述各室的尺寸可相同也可不同，如不同，最好室的尺寸越来越大。尺寸一词在这里指室的长度，但本发明的一种变形在于凹槽的深度或宽度连续变动或各室的深度或宽度不同。
小尺的刻度可呈普通刻度、凸起、凹口、一组颜色或其组合。小尺的刻度可位于凹槽内部和/或外部。
按照一种特别实施方法，该装置包括该小尺至少一端上的一操作表面。该表面比方说可为小尺一端上的一喇叭部。
按照本发明优选实施例：
-第一室能盛装药物的数量约相当于人体总表面的0.8-1.2％、最好是1％左右；
-第一和第二室能盛装药物的数量约相当于人体总表面的2.4-3.6％、最好是3％左右；
-第一、第二和第三室能盛装药物的数量约相当于人体总表面的4.8-7.1％、最好是6％左右；
-第一、第二、第三和第四室能盛装药物的数量约相当于人体总表面的7.2-10.8％、最好是9％左右。
本发明装置的突出之处在于，病人能反复使用该装置，它可供应任何性状的局部涂抹药物如液状、半液体状、胶状、油膏或药粉。
本发明装置可用任何符合卫生要求的不渗透材料如玻璃、金属、软塑料或硬塑料制成。
本发明装置的一种具体应用涉及治疗牛皮癣的药物的计量，所述药物最好是Silkis。在该应用中：
-第一室能盛装的Silkis的数量约为0.35-0.54g、最好为0.45g；
-第一和第二室能盛装的Silkis的数量约为1.08-1.62g、最好为1.30g；
-第一、第二和第三室能盛装的Silkis的数量约为2.16-3.20g、最好为2.60g；
-第一、第二、第三和第四室能盛装的Silkis的数量约为3.24-4.86g、最好为3.90g。
从以下结合附图对作为一例示性例子而非对本发明范围有所限制的治疗牛皮癣的Silkis的计量装置的说明中可清楚看出本发明的其它优点和特征，附图中：
图1为该计量装置的斜视俯视图；
图2为该计量装置的俯视图；
图3为该计量装置的侧视图；以及
图4为该计量装置的垂直剖面图。
图1、2和3示出本发明一计量装置，包括其上有用作刻度的凸起(4)的一椭圆形小尺(1)。该小尺包括其上有一系列室(3)的一纵向凹槽(2)，凹槽的一端上有一便于操作所述小尺的圆形喇叭部(5)。
在该例中，该小尺(1)呈长158mm、在具有圆形部(5)的一端宽32mm、另一端宽17mm的椭圆形。宽7mm、深2mm、长126mm的凹槽(2)伸展在纵向轴线上。该凹槽由凸起(4)分成四个室(3a、3b、3c和3d)。第一室(3a)界定一宽7mm、深2mm、长14mm的容积。第二室(3b)界定一宽7mm、深2mm、长2gmm的容积。第三室(3c)和第四室(3d)各界定一宽7mm、深2mm、长42mm的容积。图3和4示出本发明计量装置在小尺(1)的底面上有一构成凹槽(2)底部或使得该装置平放时倾斜的纵向鼓起(6)。
例1
1)要治疗的人体表面的定义
为定义在治疗牛皮癣时要治疗的人体表面，本申请人使用Wallace的9％规则的说法。因此本申请人确定下列人体表面积百分比(占人体总面积的百分比)：
-股腹沟：腹部与大腿之间＝1％
-臀沟＝1％(背部3％)
-腰部＝3％
-面部＝9％：每耳1％、每眉毛1％、下巴1％、每鼻沟1％、前额2％
2)Silkis剂量的确定
由于每天分两次涂抹的Silkis的最佳剂量为30g且人体可治疗最大表面积为人体总表面的35％，因此本申请人确定Silkis最佳剂量为30/2/35％或每次涂抹要治疗的每个百分比的人体面积为0.43g。
表1示出要治疗的人体表面的百分比与Silkis剂量之间的关系。
  ％人体表面   1％   3％   6％   9％
  Silkis剂量   1   3   6   9
  要涂抹的Silkis的数量(g)   0.45   1.30   2.60   3.90

Claims (13)

1.涂抹在皮肤上的制品、特别是药物和化妆品的计量装置，其特征在于，它包括其上有一纵向凹槽(2)的一小尺(1)，沿该纵向凹槽有一系列室(3)，所述凹槽(2)中的药物数量与待治疗的皮肤的一定表面积对应，该数量由一个或多个室(3)界定。
2.按权利要求1所述的装置，其特征在于，该小尺(1)上有刻度(4)，从凹槽的与第一室(3a)始端对应的一端到随后各室的这些刻度界定该凹槽(2)各室中的药物数量。
3.按权利要求1或2所述的装置，其特征在于，它包括至少两个(3a、3b)、最好至少三个(3a、3b、3c)、更好四个(3a、3b、3c、3d)室。
4.按权利要求2或3所述的装置，其特征在于，小尺的刻度(4)可呈普通刻度、凸起、凹口、一组颜色或其组合。
5.按上述任一权利要求所述的装置，其特征在于，第一室(3a)能盛装药物的数量约相当于人体总面积的0.8-1.2％、最好是1％左右。
6.按上述任一权利要求所述的装置，其特征在于，第一(3a)和第二(3b)室能盛装药物的数量约相当于人体总面积的2.4-3.6％、最好是3％左右。
7.按上述任一权利要求所述的装置，其特征在于，第一(3a)、第二(3b)和第三(3c)室能盛装药物的数量约相当于人体总面积的4.8-7.1％、最好是6％左右。
8.按上述任一权利要求所述的装置，其特征在于，第一(3a)、第二(3b)、第三(3c)和第四(3d)室能盛装药物的数量约相当于人体总面积的7.2-10.8％、最好是9％左右。
9.按上述任一权利要求所述的计量涂抹在皮肤上的药物的装置，其特征在于，所述药物用来治疗牛皮癣，所述药物最好是Silkis。
10.按上述任一权利要求所述的装置，其特征在于，第一室(3a)能盛装的Silkis的数量约为0.35-0.54g、最好为0.45g。
11.按上述任一权利要求所述的装置，其特征在于，第一(3a)和第二(3b)室能盛装的Silkis的数量约为1.08-1.62g、最好为1.30g。
12.按上述任一权利要求所述的装置，其特征在于，第一(3a)、第二(3b)和第三(3c)室能盛装的Silkis的数量约为2.16-3.20g、最好为2.60g。
13.按上述任一权利要求所述的装置，其特征在于，第一(3a)、第二(3b)、第三(3c)和第四(3d)室能盛装的Silkis的数量约为3.24-4.86g、最好为3.90g。
CNA2004800364515A 2003-12-08 2004-12-02 涂抹在皮肤上的制品的计量装置 Pending CN1889936A (zh)

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FR0314335A FR2863174B1 (fr) 2003-12-08 2003-12-08 Dispositif de dosage d'un produit destine a etre applique sur la peau
FR0314335 2003-12-08

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EP (1) EP1696892A1 (zh)
JP (1) JP2007517546A (zh)
KR (1) KR101187232B1 (zh)
CN (1) CN1889936A (zh)
AU (1) AU2004296576B2 (zh)
BR (1) BRPI0416431A (zh)
CA (1) CA2547673C (zh)
FR (1) FR2863174B1 (zh)
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JP2007517546A (ja) 2007-07-05
WO2005055992A1 (fr) 2005-06-23
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AU2004296576B2 (en) 2010-08-05
CA2547673C (fr) 2013-07-02
ZA200605610B (en) 2007-11-28
KR20060123276A (ko) 2006-12-01
FR2863174B1 (fr) 2006-11-24
RU2006124565A (ru) 2008-01-20
US20070191792A1 (en) 2007-08-16
FR2863174A1 (fr) 2005-06-10
BRPI0416431A (pt) 2007-02-21
MXPA06006359A (es) 2006-08-23
EP1696892A1 (fr) 2006-09-06
RU2349307C2 (ru) 2009-03-20
AU2004296576A1 (en) 2005-06-23
CA2547673A1 (fr) 2005-06-23

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