CN1929884B - Infusion set - Google Patents
Infusion set Download PDFInfo
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- CN1929884B CN1929884B CN2005800078556A CN200580007855A CN1929884B CN 1929884 B CN1929884 B CN 1929884B CN 2005800078556 A CN2005800078556 A CN 2005800078556A CN 200580007855 A CN200580007855 A CN 200580007855A CN 1929884 B CN1929884 B CN 1929884B
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- Prior art keywords
- infusion
- connector
- infusion set
- set according
- intubate
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- Expired - Fee Related
Links
- 238000001802 infusion Methods 0.000 title claims abstract description 162
- 239000000853 adhesive Substances 0.000 claims abstract description 32
- 230000001070 adhesive effect Effects 0.000 claims abstract description 32
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000012530 fluid Substances 0.000 claims abstract description 15
- 102000004877 Insulin Human genes 0.000 claims abstract description 10
- 108090001061 Insulin Proteins 0.000 claims abstract description 10
- 229940125396 insulin Drugs 0.000 claims abstract description 10
- 239000000463 material Substances 0.000 claims description 21
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 11
- 239000004033 plastic Substances 0.000 claims description 7
- 229920003023 plastic Polymers 0.000 claims description 7
- 239000010409 thin film Substances 0.000 claims description 5
- 239000004743 Polypropylene Substances 0.000 claims description 4
- -1 polypropylene Polymers 0.000 claims description 4
- 229920001155 polypropylene Polymers 0.000 claims description 4
- 238000007920 subcutaneous administration Methods 0.000 claims description 4
- 239000011505 plaster Substances 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 239000003292 glue Substances 0.000 claims description 2
- 238000003780 insertion Methods 0.000 abstract description 18
- 230000037431 insertion Effects 0.000 abstract description 18
- 230000014759 maintenance of location Effects 0.000 abstract 1
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- 239000007924 injection Substances 0.000 description 6
- 230000008901 benefit Effects 0.000 description 4
- 230000008859 change Effects 0.000 description 3
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- RYECOJGRJDOGPP-UHFFFAOYSA-N Ethylurea Chemical compound CCNC(N)=O RYECOJGRJDOGPP-UHFFFAOYSA-N 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 210000003811 finger Anatomy 0.000 description 2
- 210000005224 forefinger Anatomy 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- 208000028990 Skin injury Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
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- 125000002947 alkylene group Chemical group 0.000 description 1
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- 238000009455 aseptic packaging Methods 0.000 description 1
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- 229940079593 drug Drugs 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
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Images
Abstract
The invention relates to an infusion set for an intermittent or continuous administration of a therapeutical substance, such as insulin. The infusion set comprises an infusion part (OB) for insertion into a patient and a connector (OA) for connecting the infusion part with a medical device through a tube (7), the connector being axially displaceable relative to the infusion part. The infusion part comprises an adhesive support (1), a base part (2) with a first set of guiding means (13) and at least two retention devices (4) for locking the connector to the infusion part, a cannula extending from said base part and being in fluid communication with a cavity which is optionally covered with a membrane, the cavity is further adapted to receive a second cannula extending from the connector, which second cannula is in fluid communication with the tube.
Description
Technical field
The present invention relates to a kind of for intermittently or use continuously infusion set such as the such therapeutant of insulin.Infusion set comprises with in order to thrusting the infusion part of the intubate in patient skin, and is used for infusion part and medical devices, preferably such as the so medical conveyer device of insulin pump, the connector that couples together.
Infusion set forms a smooth trailing flank and the larger width of relative its thickness basically under its assembling form, allow thus on its skin that is flattened on patient, and alleviated thus and carry the discomfort that this infusion set produces.
The nonspecific time cycle that described infusion part is continued to grow is placed on patient's health, and described connector might often be connected and disconnect simultaneously.Thus, can disconnect with medical devices for patient, get around and reconnect on described medical devices in a certain moment afterwards.Also have, can utilize same infusion part to change between different medical devices, and only need once thrust skin operation thus, alleviated sticky feeling concerning patient.
Background technology
US Patent No.-A-5522803 discloses a kind of infusion set with infusion part and connector.Described infusion part comprise one with the soft plastics intubate that is used for receiving from described connector the cavity fluid connection of syringe needle, the pilot hole of two inclinations and two holding devices; Described connector comprises intubate, and two square guide fingers and two arms with hook portion are used for grasping the holding device on described infusion part and working at the principal plane of described infusion part.
US Patent No.-B1-6572586 discloses a kind of for the infusion set to the hypodermic layer application of fluid, and comprises the intubate housing that is suitable for being arranged on patient skin and be used for being connected to needle housing on the intubate housing.Described needle housing has pair of flexible sidewall and the elastic webbing that is connected on sidewall.Described elastic webbing can engage with the locking of described intubate housing, thus described intubate housing and needle housing are fixed together, and described elastic webbing can push in opposite directions get loose from described intubate housing when described sidewall makes this elastic webbing be out of shape under.Hollow pinhead extends out from the main body of described needle housing, is used for fluid is delivered to described intubate from fluid source.The sidewall of described needle housing extends outside the end of hollow pinhead, in order to prevent that syringe needle and polluted surface from coming in contact and damaging unintentionally.
In these two kinds of infusion sets, all form two arms along the side of connector, and be used in both cases making connector to be two arms are pressed together from the get loose action of getting off of infusion part.Compare with these infusion sets, the present invention is textural more simple, and locking mechanism according to the present invention allows that user is actual when described arm is not locked and see, and is all the more so if especially described infusion part and connector are mixed colours into different colours.
Described infusion part might connect for several times and especially disconnect with described connector, so this operation no pain and be convenient to carry out extremely important.
Summary of the invention
The object of the present invention is to provide a kind of infusion set with coupling mechanism, described coupling mechanism can connect and separate under the as far as possible little condition of the discomfort of bringing to patient, and this infusion set also is convenient to, and patient understands and operation.
According to the present invention, provide a kind of infusion set at this, comprise for the connector that inserts the infusion part in the patient body and be used for by conduit, infusion part and medical devices being coupled together.described connector can move axially with respect to described infusion part, described infusion part comprises adhesive support, with the first assembly guidance and at least two base portions that are used for described connector is locked in the holding device on infusion part, the intubate that extends out and be communicated with cavity fluid that washability ground is covered by thin film from described base portion, wherein said cavity also is suitable for receiving the second intubate that extends out from described connector, this second intubate is communicated with described catheter fluid, be suitable for the second assembly guidance of engaging with the first assembly guidance, and at least two arms, wherein said holding device extends out from the upper surface of the first type surface of described base portion, and described arm comprises the device corresponding to described holding device.
according to a further aspect in the invention, provide a kind of infusion set at this, comprise for the connector that inserts the infusion part in the patient body and be used for by conduit, infusion part and medical devices being coupled together, described connector can move axially with respect to described infusion part, described infusion part comprises adhesive support, with the first assembly guidance and at least two base portions that are used for connector is locked in the holding device on infusion part, the intubate that extends out and be communicated with cavity fluid that washability ground is covered by thin film from described base portion, wherein said cavity also is suitable for receiving the second intubate that extends out from described connector, this second intubate is communicated with catheter fluid, be suitable for the second assembly guidance of coordinating with the first assembly guidance, and at least two arms, described holding device extends out from the upper surface of the first type surface of base portion, and described arm comprises the device corresponding to holding device, it is characterized in that, being connected between each root arm and the second assembly guidance has flexibility, in order to make arm to move along the direction perpendicular to base portion, and the width of the corresponding intrument of arm must be less than the most near the distance between the middle part of the side of the holding device at infusion part middle part and infusion part.
Compare with known infusion set, aforementioned infusion set is easier to disconnect, and it is safer to it seems that patient uses.Described connector and infusion part are separated only to be needed slightly exert pressure simultaneously on two arms of described connector, and user can see between described infusion part and connector how being connected/disconnecting.
Word " cavity " refers to the inner chamber of the extension of described intubate or intubate.
In a preferred embodiment, described connector is around the principal plane of this connector with around perpendicular to described principal plane and be parallel to the plane symmetry of central axis, allows thus that the whichever major opposing side faces up all described connector to be connected on infusion part.So just make this infusion set be more convenient for operating.
The arm of described connector can be suitably obtains with being useful on gripping device that this connector is better grasped.The example of this gripping device can be the rough surface that arris, groove, groove and washability ground are made by the material different from connector self, but is not limited to this, preferably uses groove.So just can safer and more cosily operate described infusion set, cause infusion part and draw together pipe mobile risk occurs to be not intended to because having reduced finger slippage in processing procedure.
In one embodiment of the invention, described connector has material and reduces part, such as the form that is at least one groove, be preferably at least two grooves, described material reduces part and is positioned at the position that described arm is connected the connector middle part that comprises the second assembly guidance 8, and the arm of allowing thus described connector keeps moving perpendicular to described base portion in static at the second assembly guidance.So just can press in opposite directions them by promoting described arm, replacing, make described connector and infusion part disconnect.Thus, can realize in such a way connecting/disconnecting, when namely reducing the stress in material in operating process, in the connection of described connector/disconnect process, the operation transfiguration that makes locking mechanism easily and reduced the unhappy of patient.
In another embodiment, in the specific compliance section of described base portion, holding device is set.Described flexible part can be by choosing suitable material or form by very thin material section is set between described maintaining part and base portion center for described base portion, but preferably the base portion of described infusion part has the cutting part of at least two fins of at least two formation.Formed flexible part can move out outside the principal plane of described infusion part with a kind of elastic type.Thus, obtained foregoing same advantage in connecting/get loose process.
In a preferred embodiment, the intubate on described infusion part is thrust described adhesive support, makes thus described infusion part be stablized greatly with respect to the position that skin thrusts the position.Also have, so just reduced described intubate by the risk of extracting in the patient body unintentionally.
In a preferred embodiment, described adhesive support is adhesive plaster.
In a preferred embodiment, described infusion part and connector are made by two kinds of different plastic materials, such as two kinds of dissimilar polypropylene.
In a preferred embodiment, there is vision difference in the tone of the base portion of described connection and infusion part.Be convenient to thus patient and see two defibers between parts, make described locking mechanism be easier to operation.
In a preferred embodiment, described holding device is at least two forms that are placed in the step on described infusion part or connector and are the cutting section of coupling on the another one parts.Preferably, described step has leg-of-mutton side, thus this step is made the slope.Preferably, described holding device is placed on described infusion part, and the cutting section of coupling is placed on the arm of described connector.
In a preferred embodiment, described conduit is a kind of plastic material of flexibility, and preferably the remainder by means of glue and described connector couples together.
Preferably, described medical conveyer device is the delivery device such as insulin delivery device (form that for example is insulin pump).
Intubate on described connector can be a kind of hard intubate, preferably such as the such metal intubate of steel intubate.Also have, the intubate on described connector can be made and/or is to blunt by a kind of plastic material.
In a preferred embodiment, described intubate is a kind of soft intubate, preferably a kind of soft intubate of being made by plastic material.Preferably, the plastic material that is used for described flexible cannula is such material, and deflection occurs when namely having enough flexibilities with convenient moving patients, has simultaneously enough hardness and twists together avoiding, the blocking drugs supply.Also have, described material must be suitable for medicine, namely must keep minimum to the stimulation of skin, has no side effect, and must be able to not decompose etc. in vivo.Thermoplastic elastomer (TPE) (TPE) is a kind of material that satisfies these requirements.These useful elastomeric examples are: polyester ether, ECDEL, styryl TPE, alkylene TPE, polyurethane-base TPE, ester group TPE, amide groups TPE, polyolefin and silicone rubber.In a preferred embodiment, described material is selected from: polypropylene, C-FLEX
TM, C-FLEX
TMWith polyacrylic mixture, LUPOLEN
TM1840H, LUPOLEN
TM3020D, PELLETHANE
TM2363-75D, PELLETHANE
TM2363-55D, TECOTHANE
TMAnd CARBOTHANE
TM
In a preferred embodiment, described infusion part and connector are made by polypropylene.
If described infusion part might will be connected for several times and especially be disconnected with described connector; importantly the intubate on described connector is imported in the cavity of described infusion part safely, and described intubate is protected under the situation that disconnects as much as possible.Therefore, another object of the present invention is, provides a kind of and provides with improved guiding mechanism and to the intubate of connector the infusion set that improves protection.
In a preferred embodiment, the intubate of described connector extends out from the middle part of this connector, and is placed in one with respect to the position of the front portion retraction at described middle part, and at least one in the first assembly guidance comprises at least two stable vanes.
Aforementioned invention provides a kind of intubate to connector that the infusion set that improves protection is provided, and compares with known infusion set thus, is connected and disconnects with described infusion part with allowing more times number of described connector.
Many patients such as the insulin patient, must or may wish oneself to insert infusion set or place subcutaneous sensor etc.For some people, oneself carrying out that skin thrusts is the process of a difficulty, and they need a kind of device assist them in this process thus, make thus described process no longer become a large problem.
File US2003/0225373 discloses a kind of insertion apparatus for infusion part and sensor being inserted in the patient body.This device comprises housing, helical spring, safety device and is used for tilting to insert the interior parts of patient body.But this equipment is in industrialization manufacture view relative complex, and this device must come manual load with the process of very complex by patient.
WO03/026728A1 discloses a kind of injector device, comprises housing, spring, slidably bar, locking mechanism and syringe needle.
A further object of the present invention is, a kind of improved insertion apparatus is provided, and it is easy to make and is suitable for paying with the loading form, perhaps is convenient at least load.Particularly, may have the old people of some motion function problem, need a kind of insertion apparatus that occurs with the preloaded form.
Basically the advantage of vertically inserting is, is convenient to control the degree of depth that syringe needle thrusts, and controls thus the degree of depth of intubate.This point is extremely important in insertion process infusion part.
Description of drawings
Hereinafter, present invention is described in more detail with reference to the accompanying drawings.
Fig. 1 shows an infusion set embodiment, and wherein infusion part and connector are combined into one.
Fig. 2 shows an infusion set embodiment, and wherein infusion part is separated with link.
Fig. 3 shows the same infusion set embodiment that is in released state shown in Fig. 2 from different angles.
Fig. 4 shows infusion set the second embodiment that is in released state from the first angle.
Fig. 5 shows infusion set the second embodiment from different angles.
Fig. 6 shows injector device the first embodiment that separates with infusion part.
Fig. 7 shows injector device the first embodiment that combines with infusion part.
Fig. 8 shows injector device the first embodiment that combines with infusion part.
Fig. 9 shows injector device the first embodiment that pivot member wherein surrounds syringe needle.
Figure 10 shows injector device the first embodiment that is in " loaded " position.
Figure 11 shows injector device the first embodiment that is in " loaded " position from the second angle.
Figure 12 shows injector device the second embodiment that is in loading and stationary state.
Figure 13 shows injector device the second embodiment that is in resting state.
Figure 14 shows after syringe needle inserts and injector device the second embodiment before the infusion part removal with injector.
Figure 15 shows injector device the second embodiment after injector and infusion part are separated.
Figure 16 shows injector device the second embodiment after pivotal arm is arranged to surround syringe needle.
Figure 17 shows pivotal arm from the another one angle and has been arranged to surround injector device the second embodiment after syringe needle.
Figure 18 shows an infusion set that is placed on skin.
Figure 19 shows injector device the second embodiment and a credit card.
Figure 20 shows injector device the 3rd embodiment.
Figure 21 A-D shows according to the infusion part of the 3rd embodiment and the assembling process of injector device.
Figure 22 A-B shows injector device the 3rd embodiment that is about to insertion.
Figure 23 A-B shows the adhesive support on the infusion part that is hooked on slidable member.
Figure 24 A shows after inserting the injector device with infusion part, and Figure 24 B shows the injector device that inserts afterwards without infusion part.
Figure 25 shows injector device the 3rd embodiment after inserting and surrounding syringe needle.
Figure 26 shows infusion part the 3rd embodiment that is placed in on two mounting mats of independently peeling off liner.
Figure 35 A-D and 36A-D show the different step when utilizing injector device injection infusion part.
Preferred implementation
Fig. 1-3 show an infusion set embodiment.This infusion set comprises infusion part (0B) and connector (0A).Infusion part (0B) comprises the base portion (2) with principal plane, when this infusion set is attached on patient body, described principal plane is arranged essentially parallel to patient's skin, and shoulder (2a), is used for preventing that connector (0A) from getting loose unintentionally.Base portion (2) comprises the first assembly guidance (13), in the present embodiment, is the form of two stable vanes.Described base portion also comprises two holding devices (4), and they extend out from the upper surface of this base portion, in the present embodiment, is the form of two steps.Being mounted with adhesive support (1) on the inner surface of described infusion part, is adhesive plaster in the present embodiment.Intubate (5) extends out from base portion (2), and thrusts adhesive support (1) and be communicated with central cavity (3) fluid.Intubate (5) is soft intubate preferably, but also can be made of metal.The cavity (3) that is covered by thin film to washability is suitable for receiving second intubate (6) that extends out from described connector.In the embodiment shown in Fig. 2-5, the second intubate (6) extends out from the middle part of described connector, and is placed in one with respect to the position of the front portion retraction at described middle part.In the present embodiment, base portion (2) has two cutting parts (12) that form two fins, and holding device (4) is positioned on described fin.Connector (0A) comprises two arms (9), and these two arms have four and are suitable for the cutting section (10) that engages with holding device (4).Connector (0A) is around described principal plane with perpendicular to described principal plane and be parallel to the plane symmetry of main shaft, allow thus described connector in two ways with described base portion coupling.Intubate (6) is communicated with conduit (7) fluid, and conduit (7) provides and being connected such as the such medical devices of insulin pump.In the present embodiment, the middle part of described connector has the second assembly guidance (8), and this guider (8) is two symmetrically arranged groove forms of the principal plane around this connector.In the present embodiment, described connector also has the gripping device that is form of grooves.Gripping device 11 is optional, and the rough surface of being made by a kind of material different with described connector self with can being selected from arris, groove, groove or washability.
Figure 4 and 5 show another one embodiment of the present invention, and wherein connector has two grooves (14), and in the present embodiment, groove (14) is symmetrical arranged around the principal plane of this connector.But, need not to be symmetrical arranged around described principal plane for described groove, because they do not connect with infusion part.
No matter this infusion set is manually to insert or utilize injector to insert, and infusion part (0B) and connector (0A) all consign to user as two individual components in aseptic packaging.When manual insertion, infusion part (0B) will utilize the locking identical with described connector and guider (8) to combine with needle unit when transfusion.Described needle unit is with the insertion syringe needle that extends out from middle front part, and this insertion syringe needle extends through and exceed the end of intubate (5) when transfusion.Unique function of described needle unit will be the skin that thrusts user, and after this this needle unit is removed, and connected piece (0A) replacement is retained in intubate (5) subcutaneous.
Connector (0A) can be connected on a road strategic point (luer) coupling member by conduit (7).By described road strategic point joint, can use a kind of suitable therapeutant from pump, such as insulin.Described connector can also be a kind of packaged unit, with a suitable entrance that is used for the insertion syringe needle on syringe.This packaged unit can be kept somewhere in place up to three days, and user can obtain the Drug therapy by described entrance injection simultaneously, such as insulin, in order to alleviate the skin injury that causes owing to repeatedly thrusting skin.
For the user importantly, even user is not too flexible, also can change easily, be about to infusion part (0B) and engage and be disengaged with connector (0A).The present invention meets this purpose because the motion that is used for making infusion part (0B) and connector (0A) throw off locking is to press described connector between forefinger and thumb, this be a kind of simply and the motion that is easy to realize.Also have, the active force of the relative orientation that is pushed in opposite directions by forefinger and thumb respectively not only is used for making described device throw off locking, and uses when described connector is pulled away from infusion part (0B).Be easier to make connector (0A) to be disengaged in order to make, can be by choosing a kind of softness and flexible material or by making arm (9) be fastened on described middle part with more or less hardness (such as the size by the groove (14) on change connector (0A) shoulder), having very much flexibility and arm is made.
Although arm (9) has very large flexibility, must be subject to simultaneously coming from the pressure of both sides due to described device, therefore when on the skin that is placed in user, accident is very little with the danger that described connector is pulled away from described infusion part.
Advantage is according to another preferred, only needs to use very small amount of material when producing described infusion part.Infusion part (0B) can be kept to:
Elongated middle part, it comprises intubate (5), cavity (3) and guider (13);
Shoulder (2a), it is connected on described middle part, and protects the end of the moveable arm (9) on described connector when described connector and infusion part are joined together; And
Base portion (2), it has reduced to two and has been connected in described supermedial arm, and these two arms are all with holding device (4).
Fig. 6-11 show first embodiment (29) of injector device, and it can be used for the infusion part (0B) of the described infusion set of injection.In Fig. 6, this injector device and described infusion part (0B) are separated, and Fig. 7 and 8 shows the identical injector device (29) that combines with infusion part (0B).This injector device comprises housing (30), this housing (30) is with two longitudinal extension guiders (31) that are made in the present embodiment groove, with have corresponding to the guider (31a) of guider (31) but longitudinal sliding motion member (32), in the present embodiment, guider (31a) is arris.Thrust syringe needle (35) and extend out from the front portion of slidable member (32), and this syringe needle (35) is being anchored on end on slidable member (32) by surrounded corresponding to the guider of the guider (31) on infusion part (0B).Slidable member (32) can move to the position that moves forward from advanced position, and utilizes spring (34) to be driven to the position that moves forward from advanced position.Described spring is positioned between the back (33) of slidable member (32) and described housing.Washability ground has spring support (37) (Fig. 8), and this spring support (37) assembles up with the back of described housing, has reduced thus the risk that spring breaks down.This injector device also comprises for the locking device (38) that described spring is remained on compressive state, and is used for the release (39) that makes locking device be disengaged.When being disengaged, spring (34) is urged to its position that moves forward with slidable member (32) when locking device (38), will be positioned at thus the intubate importing patient body at infusion part (0B) front end place by means of syringe needle (35).After described intubate is imported, comprise that the injector device that inserts syringe needle (35) is extracted from infusion part (0B), make the insertion syringe needle be in an exposed uncovered positions.Pivot member (36) can be rocked to such position thus, namely surrounds like that as shown in Figure 9 syringe needle (35).
Figure 10 and 11 shows the identical injector device embodiment that is in loading and fixed position.The part of pivot member (36) is as locking device (38).In Figure 10, can see in the intubate (5) that how syringe needle (35) is fitted on described infusion part.Syringe needle (35) will thrust at skin and carry intubate (5) in process.After thrusting skin, the syringe needle (35) that is fixed on described injector will be pulled out, and stay described intubate and insert in the patient body.In Figure 11, show described locking device, locking device is disengaged when tongue piece (38) being pushed through the outer ledge at described housing back (33).
Figure 12 to 17 shows the second embodiment according to injector device of the present invention, and wherein pivot member (36) is fastening with respect to slidable member (32) center.Figure 12 shows the injector device that is in following state, and namely pivot member (36) is protected described syringe needle before the intubate (5) on infusion part (0B) being carried out injection.Figure 12 shows housing (30) with the longitudinal extension guider (31) of another type, is a bar in the present embodiment.Described housing also has gripping device (40), preferably is form of grooves, better grasps the device of described injector device as being used for.
On a first type surface of described injector device, show the release (39) of centralized positioning.The advantage of button release mechanism has been to reduce the risk of inclination injection.
In Figure 13, show and be ready for the injector device that syringe needle is inserted.Described pivot member with respect to the main shaft of described injector device with the angle v that approximate 90 degree away from surrounding the position, wherein said main shaft overlaps with the insertion syringe needle.Adhesive support (1) is located in such a way, and namely the intubate (5) on infusion part (0B) and syringe needle wherein (35) thrust described adhesive support by an opening of peeling off on liner.When described pivot member is substantially perpendicular to principal plane when location of described injector device, can be formed for basically realizing the assistance device of the vertical injection of described syringe needle.Also have, Figure 13 shows the inside that syringe needle (35) on described injector device is positioned at intubate (5).In Figure 14, described injector device is in the state of getting loose, and wherein syringe needle (35) will thrust skin.In the embodiment shown in fig. 14, described housing has the backstop tongue piece (43) corresponding to the projection on described slidable member, within slidable member (32) is remained on housing (30), be easy to thus extract described syringe needle, because do not exist described slidable member to skid off the risk of described housing.In Figure 15, described injector device is pulled out, and the intubate (5) that stays on infusion part (0B) is inserted in the patient body.In Figure 16 and 17, pivot member (36) is in the position that surrounds syringe needle (35), prevents that thus object comes in contact with the syringe needle (35) that has used on every side.In Figure 18, infusion part (0B) arrives from basically vertical on position the position that is arranged essentially parallel to skin.
Figure 19 shows described injector device and a credit card, is used for illustrating the size of described injector device.
In Figure 20, show the 3rd embodiment and an infusion part (0B) of injector device.The present embodiment also has the housing (30) of the guider (31) with longitudinal extension, but and the member of longitudinal sliding motion (32), this slidably member (32) textural different from the first two embodiment.Still can see in the figure pivotal arm (36) and spring (34).In the present embodiment, backstop tongue piece (43) is arranged by the center, and is the projection form that raises from the downside of housing (30).Release (39) comprises two buttons that are placed on housing (30) each side.
In Figure 21 A-D, how to show the slidable member (32) in infusion part (0B) and the 3rd embodiment and spring (34) are fitted into housing (30) within.The unit that illustrates between pivotal arm (36) and insertion section (0B) is an adapter, and it can be used for the injector of standard the different guiders (13) on infusion part (0B).
In Figure 22 A-B, show the fixture (44) that is placed on pivot member (36).The part of adhesive support (1) can be attached on described fixture provisionally, in order to fix in such a way the position of described adhesive support, namely the tacky surfaces of support member (1) will be towards patient's skin upset.Also have, can see the backstop tongue piece (43) of release (39) and projection, wherein release (39) is the form of two buttons, and a button is on a side of housing (30).
Figure 23 A-B is hooked on this adhesive support (1) on fixture (44) there is no to show in more detail under the condition of housing at least one cutting part (46) that how to utilize on adhesive support (1).
Figure 24 A shows after inserting injector device the 3rd embodiment with an infusion part, and 24B shows after inserting and at this injector device injector device after insertion section (0B) removal.
In Figure 25, the pivot member in described injector device (36) is in the position that surrounds described syringe needle.Locking tongue (45) is fixed on this position with described pivotal arm.So just make described syringe needle keep being surrounded by described pivotal arm, reduced thus the risk that someone is injured by described syringe needle.
Figure 26 shows the 3rd embodiment of infusion part (0B).Infusion part (0B) comprises base portion (2), and this base portion (2) comprises the first assembly guidance (13) that is two stable vane forms.Base portion (2) comprises two holding devices (4), and they extend out from the upper surface of this base portion (2), and triangular in shape.Facing to the side of the triangle holding device of shoulder (2a) substantially perpendicular to the surface of base portion (2), and the side that deviates from shoulder (2a) from the top of holding device (4) towards the surperficial run-off the straight of base portion (2).Adhesive support (1) is installed on the inner surface of infusion part (0B).Intubate (5) extends out from the shoulder (2a) of base portion (2), and thrusts adhesive support (1), is communicated with central cavity (3) fluid.Can be suitable for receiving the second intubate (6) that extends out from described connector by the cavity (3) that thin film covers.In the present embodiment, base portion (2) has two at the upper roomy cutting part (12) that forms two narrow fins of this base portion (2), and holding device (4) is positioned on described fin.
Near the distance between the middle part (II) of the side (I) of the holding device (4) at infusion part (0B) middle part and infusion part (0B), having limited can mobile distance at two arms (9) that are parallel on the above connector of plane of base portion (2) the most.For the corresponding intrument (10) on the arm (9) of connector (0A), width must be less than (I) and the distance (II).In a preferred embodiment, also can make connector (0A) separate with infusion part (0B) away from base portion (2) is mobile by making arm (9) in the vertical direction.If wish that this point becomes possibility, the arm (9) on so described connector need to have enough flexibilities in the position that arm (9) is fixed to described connector middle part.This point can by reducing the thickness of arm (9) until reach required flexibility and realize in this zone along at least one direction, perhaps realize by choosing a kind of material structure link (0A) with suitable flexibility.
In the present embodiment, peel off the parts that liner (41,42) is divided into a plurality of separation on adhesive support (1).First component (41) is for the protection of the part adhesive support (1) in intubate (5) the place ahead, and second component (42) is for the protection of the part adhesive support below intubate (5) rear and described infusion part.During insertion, these two separated opening of parts, the part adhesive support that is positioned at thus described intubate the place ahead can be bent upwards, and the viscosity side of adhesive support (1) be exposed to described intubate around.First component (41) is pullled backward by user, perhaps is attached on a side of described injector device; Second component (42) is attached on the opposite flank of described injector device.
Figure 35 A-E and 36A-E show respectively the use circulation of this injector device of seeing from upside (Figure 35) and the downside (Figure 36) of described injector device.
In Figure 35 A and 36A, described device is in the first state, and namely described device will be delivered to patient under aseptic condition usually.Under this state, pivotal arm (36) is in the position that surrounds syringe needle (35), and the angle v between the principal plane of described injector device and described pivotal arm is close to 0 °, in this case, if press unintentionally release (39), the tongue piece of two projections (48) will prevent that slidable member (32) is pushed forward.
In Figure 35 B and 36B, to insert thus syringe needle (35) and reveal by lifting backward pivotal arm (36), in the present embodiment, lift the part that is attached on pivotal arm (36) and peel off liner (41), manifest the adhesive support (1) of lower floor, described device is in resting state.In this position, pivotal arm (36) is allowed described syringe needle insertion, and but more than or equal to 90 degree less than or equal to 180 degree, and in this position, described injector device will be resting on patient's skin with respect to the angle v of the principal plane of described injector device.
In Figure 35 C and 36C, release (39) has been subjected to be pressed and has discharged spring (34).Described spring has promoted forward slidable member (32), until this slidable member is subject to stopping of two backstop tongue piece (43).In this position, insert the skin that syringe needle (35) has thrust patient, and a part of tacky surfaces of adhesive support (1) (this part covers described syringe needle peripheral region with the whole width of described adhesive support) and patient's skin comes in contact.In Figure 36 C, show and how the described second portion (42) of peeling off liner is attached on housing (30), and still cover described tacky surfaces when being pushed forward when slidable member (32).
In Figure 35 D and 36D, show when described injector device is taken out from patient, stay the situation of inserting subcutaneous infusion part (0B).User makes the described first component (41) of peeling off liner separate with pivotal arm (36), and thus when being pulled away from described injector device, the described second component (42) of peeling off liner also is pulled away from, manifest the tacky surfaces of adhesive support (1), and can press described adhesive support towards skin for the user, thus fixing infusion part (0B).
At last, after described insertion syringe needle is extracted, described insertion syringe needle is attached on slidable member (32) in described injector device in the present embodiment, illustrated how pivot member (36) is placed in the position that surrounds described syringe needle in Figure 35 E and 36E, prevented that thus object is stung on every side.In order to arrive this position, pivotal arm (36) is rotated about 180 degree from the position shown in Figure 35 D and 36D, and the angle w between the principal plane of described injector device and pivotal arm (36) is near 90 degree.
Claims (19)
1. infusion set, comprise for the connector (0A) that inserts the infusion part (0B) in the patient body and be used for by conduit (7), infusion part (0B) and medical devices being coupled together, described connector can move axially with respect to described infusion part, described infusion part comprises adhesive support (1), with the first assembly guidance (13) and at least two base portions (2) that are used for connector (0A) is locked in the holding device (4) on infusion part (0B), the intubate (5) that extends out and be communicated with cavity (3) fluid from described base portion (2), wherein said cavity also is suitable for receiving the second intubate (6) that extends out from described connector, this second intubate (6) is communicated with conduit (7) fluid, be suitable for the second assembly guidance (8) of coordinating with the first assembly guidance (13), and at least two arms (9), described holding device (4) extends out from the upper surface of the first type surface of base portion (2), and described arm (9) comprises the device (10) corresponding to holding device (4), it is characterized in that, being connected between each root arm (9) and the second assembly guidance (8) has flexibility, in order to make arm (9) to move along the direction perpendicular to base portion (2), and the width of the corresponding intrument (10) of arm (9) must be less than the most near the distance between the middle part of the side of the holding device (4) at infusion part (0B) middle part and infusion part (0B).
2. infusion set according to claim 1, is characterized in that, described connector is around the principal plane of this connector with around perpendicular to described principal plane and be parallel to the plane symmetry of central axis.
3. infusion set according to claim 1 and 2, it is characterized in that, reduce the thickness of arm (9) until reach required flexibility by the position that is fixed to described connector middle part at arm (9) along at least one direction, perhaps construct link (0A) by choosing a kind of material with suitable flexibility, and make being connected between each root arm (9) and the second assembly guidance (8) have flexibility.
4. infusion set according to claim 3, is characterized in that, being connected between each root arm (9) and the second assembly guidance (8) comprises at least one groove (14).
5. infusion set according to claim 1, is characterized in that, described holding device (4) is positioned at the flexible part office of base portion (2).
6. infusion set according to claim 5, is characterized in that, described base portion (2) has at least two cutting parts (12) of at least two fins of formation, and holding device (4) is positioned on described fin.
7. infusion set according to claim 1, is characterized in that, described intubate (5) is passed adhesive support (1).
8. infusion set according to claim 1, is characterized in that, described adhesive support (1) is adhesive plaster.
9. infusion set according to claim 1, is characterized in that, described infusion part (0B) and connector (0A) are made by two kinds of different plastic materials.
10. infusion set according to claim 1, is characterized in that, has vision difference on the tone of the base portion (2) of connector (0A) and infusion part (0B).
11. infusion set according to claim 1 is characterized in that, described holding device (4) is stepped form.
12. infusion set according to claim 1 is characterized in that, described holding device (4) is triangular in shape.
13. infusion set according to claim 1 is characterized in that, described conduit tightens up by means of glue.
14. infusion set according to claim 1 is characterized in that, described medical devices is an insulin pump.
15. infusion set according to claim 1 is characterized in that, described intubate (5) is a soft intubate of being made by thermoplastic elastomer (TPE) (TPE).
16. infusion set according to claim 1 is characterized in that, described infusion part (0B) and/or connector (0A) are made by polypropylene substantially.
17. infusion set according to claim 1 is characterized in that, comprises for the injector device with the subcutaneous importing patient skin of intubate (5) of described infusion part (0B).
18. infusion set according to claim 17, it is characterized in that, described injector device comprises housing (30), the guider (31) of back (33) and longitudinal extension, can and comprise member (32) for the syringe needle (35) of the cavity that inserts intubate (5) in the inner longitudinal sliding motion of housing (30), but the spring (34) between described housing back and longitudinal sliding motion member, be used for described spring is remained on the locking device of compressive state, and for the release (39) that makes described locking device be disengaged, described injector device comprises pivot member (36), this pivot member (36) can be rocked to the position that this pivot member (36) surrounds described syringe needle from allowing the position that described syringe needle is inserted.
19. infusion set according to claim 1 is characterized in that, described cavity (3) is covered by thin film.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55686304P | 2004-03-26 | 2004-03-26 | |
| DKPA200400493 | 2004-03-26 | ||
| DKPA200400493 | 2004-03-26 | ||
| US60/556,863 | 2004-03-26 | ||
| PCT/DK2005/000189 WO2005092410A1 (en) | 2004-03-26 | 2005-03-21 | Infusion set |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1929884A CN1929884A (en) | 2007-03-14 |
| CN1929884B true CN1929884B (en) | 2013-06-12 |
Family
ID=37859476
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2005800078556A Expired - Fee Related CN1929884B (en) | 2004-03-26 | 2005-03-21 | Infusion set |
| CNB2005800080787A Expired - Fee Related CN100528254C (en) | 2004-03-26 | 2005-03-21 | Injector device for infusion set |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005800080787A Expired - Fee Related CN100528254C (en) | 2004-03-26 | 2005-03-21 | Injector device for infusion set |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN1929884B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD811584S1 (en) | 2009-09-15 | 2018-02-27 | Medimop Medical Projects Ltd. | Injector device |
| US10071196B2 (en) | 2012-05-15 | 2018-09-11 | West Pharma. Services IL, Ltd. | Method for selectively powering a battery-operated drug-delivery device and device therefor |
| US10071198B2 (en) | 2012-11-02 | 2018-09-11 | West Pharma. Servicees IL, Ltd. | Adhesive structure for medical device |
| WO2013184517A1 (en) | 2012-06-06 | 2013-12-12 | Saint-Gobain Performance Plastics Corporation | Thermoplastic elastomer tubing and method to make and use same |
| WO2016196934A1 (en) | 2015-06-04 | 2016-12-08 | Medimop Medical Projects Ltd. | Cartridge insertion for drug delivery device |
| JP6957525B2 (en) | 2016-06-02 | 2021-11-02 | ウェスト ファーマ サービシーズ イスラエル リミテッド | Needle evacuation by 3 positions |
| EP3490635B1 (en) | 2016-08-01 | 2021-11-17 | West Pharma. Services Il, Ltd. | Partial door closure prevention spring |
| CN110869072B (en) | 2017-05-30 | 2021-12-10 | 西部制药服务有限公司(以色列) | Modular drive mechanism for a wearable injector |
| US11857767B2 (en) | 2017-12-22 | 2024-01-02 | West Pharma. Services IL, Ltd. | Injector usable with different dimension cartridges |
| EP3744367A1 (en) * | 2019-05-29 | 2020-12-02 | Sooil Development Co., Ltd. | Needle infusion set for insulin infusion |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5522803A (en) * | 1993-03-09 | 1996-06-04 | Pharma Plast International A/S | Infusion set for an intermittent or continuous administration of a therapeutical substance |
| US6572586B1 (en) * | 2000-07-25 | 2003-06-03 | Animas Corporation | Low profile infusion set |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2752164B1 (en) * | 1996-08-09 | 1998-10-30 | Vygon | DEVICE FOR PERFORMING A PUNCTURE THROUGH THE SKIN BY MEANS OF A NEEDLE |
| US6830562B2 (en) * | 2001-09-27 | 2004-12-14 | Unomedical A/S | Injector device for placing a subcutaneous infusion set |
| CA2422307A1 (en) * | 2002-03-20 | 2003-09-20 | Stefanie Livanos | Blood collection device |
-
2005
- 2005-03-21 CN CN2005800078556A patent/CN1929884B/en not_active Expired - Fee Related
- 2005-03-21 CN CNB2005800080787A patent/CN100528254C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5522803A (en) * | 1993-03-09 | 1996-06-04 | Pharma Plast International A/S | Infusion set for an intermittent or continuous administration of a therapeutical substance |
| US6572586B1 (en) * | 2000-07-25 | 2003-06-03 | Animas Corporation | Low profile infusion set |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1929885A (en) | 2007-03-14 |
| CN100528254C (en) | 2009-08-19 |
| CN1929884A (en) | 2007-03-14 |
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