CN1985750A - Pulse wave detecting method and device by means of cardiac symbol signal - Google Patents

Pulse wave detecting method and device by means of cardiac symbol signal Download PDF

Info

Publication number
CN1985750A
CN1985750A CN 200510022395 CN200510022395A CN1985750A CN 1985750 A CN1985750 A CN 1985750A CN 200510022395 CN200510022395 CN 200510022395 CN 200510022395 A CN200510022395 A CN 200510022395A CN 1985750 A CN1985750 A CN 1985750A
Authority
CN
China
Prior art keywords
pulse wave
delay
pressure
cardiac
length
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN 200510022395
Other languages
Chinese (zh)
Other versions
CN1985750B (en
Inventor
胡刚
陶波
叶继伦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Mindray Bio Medical Electronics Co Ltd
Original Assignee
Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Mindray Bio Medical Electronics Co Ltd filed Critical Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority to CN2005100223956A priority Critical patent/CN1985750B/en
Publication of CN1985750A publication Critical patent/CN1985750A/en
Application granted granted Critical
Publication of CN1985750B publication Critical patent/CN1985750B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Abstract

The present invention discloses method and device for detecting pulse wave by means of cardiac symbol signal. Through detecting the temporal interval between the R wave and the pulse wave, obtain reference interval value, locating searched pulse wave amplitude with the reference interval value and obtaining reference pulse wave amplitude under different pressures, the mean pressure, the systolic pressure and the diastolic pressure are calculated by means of the ratio process. Compared with the available method to search pulse wave peak directly in the pulse wave signal, the present invention has raised anti-jamming capacity and raised blood pressure measuring accuracy especially in case of sports and arrhythmia.

Description

A kind of method and device that utilizes means of cardiac symbol signal detection pulse wave
[technical field]
The present invention relates to a kind of pulse wave detection method, relate in particular to and utilize electrocardiosignal to instruct the pulse wave detection method and the device of searching, strengthen interference free performance of pulse wave and the electric sphygmomanometer that comprises this device.
[background technology]
Carry out non-invasive blood pressure at present when measuring, adopt succusion usually, its measuring process is earlier to the cuff inflation, after pressure reaches systolic pressure greater than human body, can think that then blood vessel blocks fully, at this moment, should not have beating of pulse at the cuff place.Begin slowly venting or step venting then, when cuff pressure during less than systolic pressure, blood vessel has had the part conducting, pulse was beaten and can be strengthened gradually along with the decline of cuff pressure this moment, because the influence that pulse is beaten, with making the pressure appearance fluctuation among a small circle of cuff, that is to say the oscillator signal that on pressure signal, superposeed, same this oscillator signal strengthens gradually along with the decline of cuff pressure.But after cuff pressure was reduced to a certain degree, the amplitude of oscillator signal can begin to descend on the contrary.This mainly is because cuff pressure reduces, and makes the attenuation that subcutis is beaten to pulse strengthen gradually.Descend when cuff pressure is lasting, this attenuation is more and more obvious, and the amplitude of oscillator signal descends also obvious more.By the pulse wave amplitude under the search different pressures, obtain the corresponding relation curve of pulse pressure and pulse wave amplitude.Search the pressure of maximum pulse wave amplitude correspondence then, think mean pressure; Utilize the pulse wave amplitude of mean pressure correspondence, multiply by the systolic pressure range coefficient, obtain the pulse wave amplitude of systolic pressure correspondence, calculate corresponding cuff pressure according to the corresponding relation curve to the high telegoniometer of cuff pressure then, think systolic pressure; Utilize the pulse wave amplitude of mean pressure correspondence, multiply by the diastolic pressure range coefficient, obtain the pulse wave amplitude of diastolic pressure correspondence, calculate the pressure of cuff then to the low telegoniometer of cuff pressure according to the corresponding relation curve, think diastolic pressure, the method for this calculating mean pressure, systolic pressure and diastolic pressure is called ratio method.In traditional measuring method, measurement result is easy to be subjected to various interference such as arm motion, causes can not surveying the result even measures the bigger result of deviation.
Need be strapped in oversleeve on the patients arm when measuring and be inflated to certain pressure, patient inevitably feels compressing, shake can appear under unconscious situation, perhaps patient's the state of an illness causes occurring situations such as amyostasia, perhaps under operation process or other situation, patient's arm is subjected to extraneous shake-up and unexpected shake etc., under these situations, the baseline of pulse wave and amplitude can be affected, the method of traditional searching pulse wave amplitude is difficult to guarantee its accuracy that the probability that causes recognizing wrong pulse wave amplitude increases.
[summary of the invention]
Main purpose of the present invention is exactly in order to solve prior art problems, and a kind of method that detects pulse wave is provided, and utilizes the means of cardiac symbol signal of reflection heartbeat to reduce interference, improves the accuracy that pulse wave detects.
Another object of the present invention is exactly in order to solve prior art problems, and a kind of pulse wave detection device is provided, and utilizes the means of cardiac symbol signal of reflection heartbeat to reduce interference, improves the accuracy that pulse wave detects.
Another purpose of the present invention just provides a kind of electric sphygmomanometer, improves the accuracy of pulse wave curves, utilizes succusion to measure accuracy of blood pressure thereby improve.
For achieving the above object, the invention discloses a kind of method of utilizing means of cardiac symbol signal detection pulse wave, may further comprise the steps:
A1, cuff is arranged on the regulation position of health;
B1, control cuff are inflated to certain pressure, make cuff compressing tremulous pulse, then venting gradually;
C1, in deflation course, the pressure of sampling in the cuff;
D1, detect the pulse wave under this pressure, sampling electrocardiosignal, and moment of occurring because of means of cardiac symbol signal that heartbeat produced of record;
E1, detect the reference length of delay of pulse wave with respect to the means of cardiac symbol signal;
Search for pulse wave in F1, the effective range after means of cardiac symbol signal delay is with reference to length of delay;
The pulse wave that G1, basis search out obtains the benchmark pulse wave under this pressure.
Wherein, described means of cardiac symbol signal is preferably R ripple or blood oxygen pulse ripple.
Wherein, described effective range is for the point of means of cardiac symbol signal delay after with reference to length of delay being 1/15 second scopes before and after the center.
Wherein, the preferred version of described step e 1 may further comprise the steps:
Distance values between E11, detection means of cardiac symbol signal and the detected pulse wave;
E12, set up the spacing array, the distance values in the described spacing array differs between any two all less than setting difference;
E13, with the average back of the distance values in the spacing array as with reference to length of delay.
The preferred version of above-mentioned steps is: the minimum number of the distance values in the described distance values array is 3, and described setting difference is 1/15 second.
For constantly the reference length of delay being revised, further comprising the steps of after step e 13:
Search for next pulse wave in E14, the effective range after means of cardiac symbol signal delay is with reference to length of delay, and the distance values of this pulse wave and corresponding means of cardiac symbol signal is added the spacing array;
E15, the distance values of spacing array is sorted, seek with array in other distance values differ in twos less than the set of setting the maximum distance values of difference;
The meansigma methods of distance values is upgraded with reference to length of delay in E16, the usefulness set.
For achieving the above object, the invention also discloses a kind of pulse wave detection device, comprising: cuff is arranged on the regulation position of health; The air pressure control module is inflated to certain pressure to cuff, makes cuff compressing tremulous pulse, and can exit gradually; The pressure detecting module detects the pressure in the described cuff; The pulse wave detection module detects pulse and beats because of the pulse wave signal that produced by the cuff compressing; The electrocardiosignal detection module detects because of the means of cardiac symbol signal that heartbeat produced, and writes down the moment of its appearance; With reference to the length of delay detection module, detect pulse wave with respect to the means of cardiac symbol signal in time the reference length of delay; The pulse wave search module is used for searching for pulse wave in the effective range after means of cardiac symbol signal delay is with reference to length of delay; Benchmark pulse wave computing module obtains benchmark pulse wave under the different pressures according to the pulse wave that searches out.
Wherein, described means of cardiac symbol signal is preferably R ripple or blood oxygen pulse ripple.
Wherein, described effective range is for the point of means of cardiac symbol signal delay after with reference to length of delay being 1/15 second scopes before and after the center.
Describedly comprise with reference to the length of delay detection module: the distance values detecting unit, detect the distance values between means of cardiac symbol signal and the detected pulse wave; The spacing array is set up in spacing array manipulation unit, and the distance values in the described spacing array differs between any two all less than setting difference; With reference to the length of delay computing unit, with the average back of the distance values in the spacing array as with reference to length of delay.
Preferably 3 of the minimum numbers of the distance values in the described distance values array, described setting difference is preferably 1/15 second.
For constantly the reference length of delay being revised, further improvement of the present invention is: also comprise with reference to the length of delay update module, the distance values that is used for the next pulse wave that will search and corresponding means of cardiac symbol signal in the effective range after means of cardiac symbol signal delay is with reference to length of delay adds the spacing array, the distance values of spacing array is sorted, other distance values in searching and the array differ in twos less than the set of setting the maximum distance values of difference, upgrade with reference to the reference length of delay in the length of delay detection module with the meansigma methods of gathering interior distance values.
For achieving the above object, the invention also discloses a kind of electric sphygmomanometer, comprising: cuff is arranged on the regulation position of health; The air pressure control module is inflated to certain pressure to cuff, makes cuff compressing tremulous pulse, and can exit gradually; The pressure detecting module detects the pressure in the described cuff; The pulse wave detection module detects pulse and beats because of the pulse wave signal that produced by the cuff compressing; The electrocardiosignal detection module detects because of the means of cardiac symbol signal that heartbeat produced, and writes down the moment of its appearance; With reference to the length of delay detection module, detect pulse wave with respect to the means of cardiac symbol signal in time the reference length of delay; The pulse wave search module is used for searching for pulse wave in the effective range after means of cardiac symbol signal delay is with reference to length of delay; Benchmark pulse wave computing module obtains benchmark pulse wave under the different pressures according to the pulse wave that searches out; The blood pressure computing module according to pressure sequence that draws and benchmark pulse wave sequence, adopts ratio method to calculate mean pressure, systolic pressure and diastolic pressure.
For achieving the above object, the invention also discloses a kind of electric sphygmomanometer, comprising: cuff is arranged on the regulation position of health; The air pressure control module is inflated to certain pressure to cuff, makes cuff compressing tremulous pulse, and can exit gradually; The pressure detecting module detects the pressure in the described cuff; The pulse wave detection module detects pulse and beats because of the pulse wave signal that produced by the cuff compressing; The electrocardiosignal detection module detects because of the means of cardiac symbol signal that heartbeat produced, and writes down the moment of its appearance; Processing module, be used to detect the reference length of delay of pulse wave with respect to the means of cardiac symbol signal, search for pulse wave in the effective range after means of cardiac symbol signal delay is with reference to length of delay, obtain benchmark pulse wave under the different pressures according to the pulse wave that searches out, according to pressure sequence that draws and benchmark pulse wave sequence, adopt ratio method to calculate mean pressure, systolic pressure and diastolic pressure.
Effect of the present invention: 1) utilize the blood that sprays behind the heartbeat compressing power of blood vessel to be delivered to the principle that time delay of arm vessel arms same individual is remained unchanged substantially, occur seeking pulse wave in the set time zone, back at R ripple or blood oxygen pulse ripple, can effectively get rid of interference, improve the accuracy that pulse wave detects.2) rationally detect the reference length of delay of R ripple or blood oxygen pulse ripple and pulse wave, help the fixed-position searching of pulse wave, the more progressive minimizing the probability of interfering signal as pulse wave.3) according to the R ripple that detects later or blood oxygen pulse ripple and pulse wave, constantly revise with reference to length of delay, be used in instruct the pulse wave fixed-position searching the reference length of delay more near actual pitch, further improved anti-interference and accuracy that pulse wave detects again.
Feature of the present invention and advantage will be elaborated in conjunction with the accompanying drawings by embodiment.
[description of drawings]
Fig. 1 is the connection block diagram of an embodiment of the present invention;
Fig. 2 is the flow chart of an embodiment of the present invention;
Fig. 3 is the flow chart that obtains among Fig. 2 with reference to length of delay;
Fig. 4 is the flow chart that upgrades with reference to length of delay;
Fig. 5 is the flow chart that instructs the pulse wave fixed-position searching among Fig. 2 with the R ripple.
[specific embodiment]
As shown in Figure 1, cuff is used for being worn on the regulation position of tested health when measuring blood pressure, normally be worn on the arm, also can be worn on the wrist.The air pressure control module is connected with cuff, and the air pressure control module comprises motor, inflation unit, valve and logic control element, and motor, inflation unit, cuff, valve constitute gas fill port, are subjected to the control of logic control element.At first valve-off powers on to motor, allows oversleeve be inflated to specified pressure, stops inflation then, opens valve, and the control vent valve is exitted gradually to cuff, for example step venting.The pressure detecting module comprises pressure transducer, amplifier and A/D converter, pressure transducer is placed in the cuff close with tremulous pulse, in deflation course, pressure transducer detects the pressure in the cuff, convert pressure to signal of telecommunication output, amplifier amplifies the signal of telecommunication, is divided into two-way then, wherein the first via directly outputs to A/D converter, calculates the back and obtains current pressure.The second the tunnel outputs to the pulse wave detection module, and the pulse wave detection module comprises high pass filter, filters the pressure signal of direct current, amplifies then to output to A/D converter, obtains alternative pulse wave signal.The electrocardiosignal detection module utilizes existing means to detect the R ripple, and writes down the moment of its appearance.Receive the R ripple of electrocardiosignal detection module output and the moment of its appearance with reference to the length of delay detection module, also receive simultaneously the pulse wave of pulse wave detection module output, pulse wave and R phase of wave are compared, detect pulse wave with respect to R ripple reference length of delay in time.The pulse wave search module instructs the fixed-position searching of pulse wave according to the reference length of delay, the moment that is about to the appearance of R ripple postpones with reference to searching for pulse wave in the effective range behind the length of delay, it is 1/15 second scopes before and after the center that this effective range is preferably the point of delay after with reference to length of delay, if the sample frequency with 75Hz is sampled, then this effective range is 5 sampled points in front and back at center for postponing with reference to the point behind the length of delay, the pulse wave that in this scope, searches not, thinking not to be the blood pressure pulse wave amplitude, is to disturb.Receive the next pulse wave that the pulse wave search module searches with reference to the length of delay update module in the R ripple postpones with reference to the effective range behind the length of delay, and the distance values of this pulse wave and corresponding means of cardiac symbol signal added the spacing array, the distance values of spacing array is sorted, other distance values in searching and the array differ in twos less than the set of setting the maximum point of difference, upgrade with reference to the reference length of delay in the length of delay detection module with the meansigma methods of gathering interior distance values.Benchmark pulse wave computing module adopts similar ripple clustering procedure according to several pulse wave peak values that find under the same pressure, finds out similar pulse wave amplitude, and average back is as the benchmark pulse wave amplitude under the current pressure.Above-mentioned each module is formed pulse wave detection device, can be stored in earlier in the memory module with the pressure sequence after the A/D conversion with the corresponding benchmark pulse wave of pressure sequence then, the optimization process module reads pressure sequence and the benchmark pulse wave sequence in the memory module, pressure sequence and benchmark pulse wave sequence are carried out normalization, interpolation, processing such as weighted average, output to the blood pressure computing module then, the blood pressure computing module adopts ratio method to calculate mean pressure, systolic pressure and diastolic pressure, because of having improved the accuracy of pulse wave curves, thereby realize the anti-interference of blood pressure measurement, improve and utilize succusion to measure accuracy of blood pressure.Can also further calculate pulse frequency.
Above-mentioned reference length of delay detection module, can also be integrated in the processing module with reference to length of delay update module, pulse wave search module, benchmark pulse wave computing module, memory module, optimization process module and blood pressure computing module, the employing software mode is finished, and for example is integrated in the single-chip microcomputer.
Because R ripple, blood oxygen pulse period of wave and pulse wave cycle reaction all is palmic rate, so the spacing of corresponding R ripple or blood oxygen pulse ripple and pulse wave is certain, this spacing reaction is for behind heartbeat, the blood transmission was pulsed to the time of arm, for this time delay of same individual is certain, does not have what variation.According to this feature, can only behind R ripple or blood oxygen pulse ripple, seek pulse wave in the determining deviation, can effectively remove interference.The idiographic flow of present embodiment may further comprise the steps as shown in Figure 2:
In step 1, cuff filled be deflated to a pressure step;
In step 2, under the current pressure step, in regularly interrupting, oscillator signal be that is to say that pulse wave signal samples, and sampled data is carried out pretreatment; Wave impulse is sampled to R, and the moment of record R wave impulse appearance, and execution in step 3 then;
In step 3, judge whether to be first pressure step, if then execution in step 4, if not execution in step 5 then;
In step 4, obtain the reference distance values between R ripple and the corresponding pulse wave, execution in step 6 then;
In step 5, upgrade with reference to distance values, execution in step 6 then;
In step 6, according to the hunting zone of reference distance values location pulse wave, and search out pulse wave in this scope, the preferred version of its hunting zone is that postponing the R ripple with reference to the point behind the length of delay is the pulse wave in 1/15 second scope before and after the center.Execution in step 7 then;
In step 7, the pulse wave under the same pressure is carried out similar clustering procedure handle, find out similar pulse wave amplitude, average back is as the benchmark pulse wave amplitude under the current pressure, and execution in step 10 then;
In step 8, in regularly interrupting, the cuff pressure value is sampled, execution in step 9 then;
In step 9, the force samples signal is handled, and converted sampled value to pressure unit mmHg value, obtain the current pressure value, execution in step 10 then;
In step 10, judge whether to continue venting, continue venting if desired, then turn to execution in step 1, if do not need to continue venting, then execution in step 11;
In step 11, obtain pressure sequence and benchmark pulse wave sequence.
Utilize pulse wave to come calculating blood pressure if desired, can be more further execution in step 12;
In step 12, pressure sequence and benchmark pulse wave sequence are optimized processing, for example normalization, interpolation and weighted average are handled, and execution in step 13 then;
In step 13, find out the pulse wave of amplitude maximum, the pairing force value of this pulse wave amplitude is mean pressure, execution in step 14 then;
In step 14, rule of thumb the range coefficient of gained utilizes ratio method to calculate systolic pressure and diastolic pressure.
Can also carry out variation tendency for a series of benchmark pulse wave signals that obtain under different pressures judges, for not satisfying the pulse wave amplitude of pulse wave amplitude variation tendency deletion under the pressure in the deflation course, meet required some the satisfied characteristics of ratio method to guarantee this benchmark pulse wave sequence.
In the above-mentioned steps, obtain first as shown in Figure 3, may further comprise the steps with reference to the flow process of length of delay:
In step 401, receive R ripple and the pulse wave corresponding with this R ripple, detect the distance values between R ripple and this pulse wave, execution in step 402 then;
In step 402, set up the spacing array, distance values is put into the spacing array, execution in step 403 then;
In step 403, whether the quantity of judging distance values in the spacing array greater than 2, if execution in step 404 then if not then turning to execution in step 401, continues to detect the distance values between R ripple and the next pulse wave;
In step 404, calculate the distance values difference between any two in the spacing array, if differing of this distance values and other distance values all less than 1/15 second, then this distance values is retained in the spacing array, execution in step 405 then, if the difference of this distance values and other distance values is not all less than 1/15 second, then with this distance values deletion; In this step, to set difference and be preferably 1/15 second, be because set the too little easy omission blood pressure pulse of the words ripple of difference, sets the too big words interference free performance of difference and can reduce, if the sample frequency with 75Hz is sampled, then set difference and be preferably 5 sampled points;
In step 405, judge whether the quantity of the distance values in the spacing array reaches 3, if execution in step 406 then, if not execution in step 401 then;
In step 406, with the average back of the distance values in the spacing array as with reference to length of delay.
In the above-mentioned steps, upgrade as shown in Figure 4, may further comprise the steps with reference to the flow process of length of delay:
In step 501, the next pulse wave of search in the R ripple postpones with reference to the effective range behind the length of delay, execution in step 502 then;
In step 502, in the search of pulse wave, found trough and pulse wave datum mark, execution in step 503 then;
In step 503, calculate the distance values between this pulse wave and the previous R ripple, and this distance values is added the spacing array, execution in step 504 then;
In step 504, whether the quantity of distance values of judging the spacing array greater than 2, if execution in step 505 then if not then turning to step 501, continues the next pulse wave of search;
In step 505, the distance values of spacing array is sorted, execution in step 506 then;
In step 506, other distance values in searching and the array differ in twos less than 5 maximum distance values, form set, if qualified distance values has only one, then this distance values and near its distance values are formed set together, and execution in step 507 then;
In step 507, the distance values in the set is averaged, execution in step 508 then;
In step 508, be updated to reference to length of delay with the meansigma methods of gathering interior distance values.
Wherein the flow process that instructs the pulse wave fixed-position searching with the R ripple may further comprise the steps as shown in Figure 5:
In step 601, the next pulse wave of search in the R ripple postpones with reference to the effective range behind the length of delay, execution in step 602 then;
In step 602, judge that distance values between this pulse wave and the corresponding R ripple is whether in positive and negative 5 scope of reference length of delay, judge promptly whether this pulse wave is being in the scope of 5 points in front and back, center with reference to the point behind the length of delay with the delay of R ripple, if execution in step 603 then, if not then this pulse wave being abandoned, execution in step 601 then;
In step 603, preserve current pulse wave amplitude, enter the pulse wave sequence and judge.
Through test chamber test proof, using the BIO-TECK simulator, export under the situation of various interference types, introduce the algorithm that ecg-r wave is located the pulse wave search, energy measurement goes out blood pressure result more accurately, and comparing result sees Table 1.
Table 1
Patient's pattern Simulator is set Old algorithm measurement result The new algorithm test result
The motion of Mild Exercise moderate 140/106/90 120BPM ?149/110/96 ?119BPM ?147/110/97 ?119BPM
The old and feeble pattern of Geriatric Subject 150/123/110 95BPM ?163/126/115 ?95BPM ?156/126/115 ?96BPM
Artial Fib and PVC premature beat patient 139/94/72 91BPM ?127/95/8081BPM ?138/97/8283BPM
High Way Level 8 sport ranks 8 120/93/80 ?135/91/82 ?120/93/80
As can be seen from the table, under four kinds of patterns, add the anti-interference algorithm of R ripple, measurement accuracy obviously improves, and under sport rank 8 patterns, introduces the anti-interference algorithm of R ripple especially, can calculate pressure value accurately.
In like manner, change the ecg-r wave in the foregoing description on the blood oxygen pulse ripple characteristic point,, also can be used for instructing and locating the search of blood pressure pulse ripple such as peak point or valley point.
In sum, the present invention adopts the ecg-r wave signal to come localized search pulse wave amplitude, compare with the method for directly in pulse wave signal, searching for the pulse wave peak value that current most of blood pressure measurements adopt, improved anti-jamming capacity, under the situation that motion, arrhythmia exist, can effectively improve the blood pressure measurement accuracy.

Claims (14)

1. method of utilizing means of cardiac symbol signal detection pulse wave is characterized in that may further comprise the steps:
A1, cuff is arranged on the regulation position of health;
B1, control cuff are inflated to certain pressure, make cuff compressing tremulous pulse, then venting gradually;
C1, in deflation course, the pressure of sampling in the cuff;
D1, detect the pulse wave under this pressure, sampling electrocardiosignal, and moment of occurring because of means of cardiac symbol signal that heartbeat produced of record;
E1, detect the reference length of delay of pulse wave with respect to the means of cardiac symbol signal;
Search for pulse wave in F1, the effective range after means of cardiac symbol signal delay is with reference to length of delay;
The pulse wave that G1, basis search out obtains the benchmark pulse wave under this pressure.
2. the method for claim 1, it is characterized in that: described means of cardiac symbol signal is R ripple or blood oxygen pulse ripple.
3. method as claimed in claim 2 is characterized in that: described effective range is for the point of means of cardiac symbol signal delay after with reference to length of delay being 1/15 second scopes before and after the center.
4. as each described method in the claim 1 to 3, it is characterized in that: described step e 1 may further comprise the steps:
Distance values between E11, detection means of cardiac symbol signal and the detected pulse wave;
E12, set up the spacing array, the distance values in the described spacing array differs between any two all less than setting difference;
E13, with the average back of the distance values in the spacing array as with reference to length of delay.
5. method as claimed in claim 4 is characterized in that: the minimum number of the distance values in the described distance values array is 3, and described setting difference is 1/15 second.
6. as claim 4 or 5 described methods, it is characterized in that after step e 13 further comprising the steps of:
Search for next pulse wave in E14, the effective range after means of cardiac symbol signal delay is with reference to length of delay, and the distance values of this pulse wave and corresponding means of cardiac symbol signal is added the spacing array;
E15, the distance values of spacing array is sorted, seek with array in other distance values differ in twos less than the set of setting the maximum distance values of difference;
The meansigma methods of distance values is upgraded with reference to length of delay in E16, the usefulness set.
7. pulse wave detection device comprises:
Cuff is arranged on the regulation position of health;
The air pressure control module is inflated to certain pressure to cuff, makes cuff compressing tremulous pulse, and can exit gradually;
The pressure detecting module detects the pressure in the described cuff;
The pulse wave detection module detects pulse and beats because of the pulse wave signal that produced by the cuff compressing; It is characterized in that also comprising:
The electrocardiosignal detection module detects because of the means of cardiac symbol signal that heartbeat produced, and writes down the moment of its appearance;
With reference to the length of delay detection module, detect the reference length of delay of pulse wave with respect to the means of cardiac symbol signal;
The pulse wave search module is used for searching for pulse wave in the effective range after means of cardiac symbol signal delay is with reference to length of delay;
Benchmark pulse wave computing module obtains benchmark pulse wave under the different pressures according to the pulse wave that searches out.
8. pulse wave detection device as claimed in claim 7 is characterized in that: described means of cardiac symbol signal is R ripple or blood oxygen pulse ripple.
9. pulse wave detection device as claimed in claim 8 is characterized in that: described effective range is for the point of means of cardiac symbol signal delay after with reference to length of delay being 1/15 second scopes before and after the center.
10. as each described pulse wave detection device in the claim 7 to 9, it is characterized in that: describedly comprise with reference to the length of delay detection module:
The distance values detecting unit detects the distance values between means of cardiac symbol signal and the detected pulse wave;
Spacing array manipulation unit: set up the spacing array, the distance values in the described spacing array differs between any two all less than setting difference;
With reference to the length of delay computing unit, with the average back of the distance values in the spacing array as with reference to length of delay.
11. pulse wave detection device as claimed in claim 10 is characterized in that: the minimum number of the distance values in the described distance values array is 3, and described setting difference is 1/15 second.
12., it is characterized in that also comprising as claim 10 or 11 described pulse wave detection devices:
With reference to the length of delay update module, the distance values that is used for the next pulse wave that will search and corresponding means of cardiac symbol signal in the effective range after means of cardiac symbol signal delay is with reference to length of delay adds the spacing array, the distance values of spacing array is sorted, other distance values in searching and the array differ in twos less than the set of setting the maximum distance values of difference, upgrade with reference to the reference length of delay in the length of delay detection module with the meansigma methods of gathering interior distance values.
13. an electric sphygmomanometer comprises:
Cuff is arranged on the regulation position of health;
The air pressure control module is inflated to certain pressure to cuff, makes cuff compressing tremulous pulse, and can exit gradually;
The pressure detecting module detects the pressure in the described cuff;
The pulse wave detection module detects pulse and beats because of the pulse wave signal that produced by the cuff compressing; It is characterized in that also comprising:
The electrocardiosignal detection module detects because of the means of cardiac symbol signal that heartbeat produced, and writes down the moment of its appearance;
With reference to the length of delay detection module, detect the reference length of delay of pulse wave with respect to the means of cardiac symbol signal;
The pulse wave search module is used for searching for pulse wave in the effective range after means of cardiac symbol signal delay is with reference to length of delay;
Benchmark pulse wave computing module obtains benchmark pulse wave under the different pressures according to the pulse wave that searches out;
The blood pressure computing module according to pressure sequence that draws and benchmark pulse wave sequence, adopts ratio method to calculate mean pressure, systolic pressure and diastolic pressure.
14. an electric sphygmomanometer comprises:
Cuff is arranged on the regulation position of health;
The air pressure control module is inflated to certain pressure to cuff, makes cuff compressing tremulous pulse, and can exit gradually;
The pressure detecting module detects the pressure in the described cuff;
The pulse wave detection module detects pulse and beats because of the pulse wave signal that produced by the cuff compressing; It is characterized in that also comprising:
The electrocardiosignal detection module detects because of the means of cardiac symbol signal that heartbeat produced, and writes down the moment of its appearance;
Processing module, be used to detect the reference length of delay of pulse wave with respect to the means of cardiac symbol signal, search for pulse wave in the effective range after means of cardiac symbol signal delay is with reference to length of delay, obtain benchmark pulse wave under this pressure according to the pulse wave that searches out, according to pressure sequence that draws and benchmark pulse wave sequence, adopt ratio method to calculate mean pressure, systolic pressure and diastolic pressure.
CN2005100223956A 2005-12-21 2005-12-21 Pulse wave detecting method and device by means of cardiac symbol signal Active CN1985750B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2005100223956A CN1985750B (en) 2005-12-21 2005-12-21 Pulse wave detecting method and device by means of cardiac symbol signal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2005100223956A CN1985750B (en) 2005-12-21 2005-12-21 Pulse wave detecting method and device by means of cardiac symbol signal

Publications (2)

Publication Number Publication Date
CN1985750A true CN1985750A (en) 2007-06-27
CN1985750B CN1985750B (en) 2011-03-23

Family

ID=38182788

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005100223956A Active CN1985750B (en) 2005-12-21 2005-12-21 Pulse wave detecting method and device by means of cardiac symbol signal

Country Status (1)

Country Link
CN (1) CN1985750B (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101773388A (en) * 2010-02-26 2010-07-14 深圳和而泰智能控制股份有限公司 Method and device for accurately measuring blood pressure
CN101912259A (en) * 2010-08-06 2010-12-15 深圳瑞光康泰科技有限公司 Non-invasive blood pressure measuring device and measuring method thereof
CN102551708A (en) * 2010-10-14 2012-07-11 株式会社电装 Living body state monitor apparatus
CN101991410B (en) * 2009-08-31 2012-09-19 深圳市理邦精密仪器股份有限公司 Pulse rate searching and calculating method
US8588896B2 (en) 2008-03-07 2013-11-19 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US8600489B2 (en) 2008-05-07 2013-12-03 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
CN102056646B (en) * 2008-03-07 2015-10-21 卡梅伦保健公司 Cardiac event accurately in implantable cardiac stimulus device detects
CN105310673A (en) * 2014-07-30 2016-02-10 日本光电工业株式会社 Biological information measuring apparatus and biological information measuring method
US9554714B2 (en) 2014-08-14 2017-01-31 Cameron Health Inc. Use of detection profiles in an implantable medical device
CN108882872A (en) * 2016-04-15 2018-11-23 欧姆龙株式会社 Biont information analytical equipment, Biont information analysis system, program and Biont information analysis method
CN109009051A (en) * 2018-06-26 2018-12-18 广州视源电子科技股份有限公司 Method for measuring heart rate, device, equipment and storage medium
WO2019227329A1 (en) * 2018-05-30 2019-12-05 深圳迈瑞生物医疗电子股份有限公司 Method for optimizing blood pressure measurement, and blood pressure measurement apparatus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3533912A1 (en) * 1985-09-23 1987-04-02 Schmid Walter Sphygmomanometer
US5339822A (en) * 1991-05-07 1994-08-23 Protocol Systems, Inc. Method of validating physiologic events resulting from a heartbeat
JP2764702B2 (en) * 1994-03-30 1998-06-11 日本光電工業株式会社 Blood pressure monitoring device
US5743856A (en) * 1995-11-06 1998-04-28 Colin Corporation Apparatus for measuring pulse-wave propagation velocity
CN100346740C (en) * 2003-05-20 2007-11-07 香港中文大学 Blood pressure measuring device and method based on the pulse information of radial artery
CN1307937C (en) * 2003-05-22 2007-04-04 香港中文大学 Signal top searcher and searching method and application in blood pressure measurement
CN1237936C (en) * 2003-07-07 2006-01-25 深圳迈瑞生物医疗电子股份有限公司 Electronic device for measuring blood-pressure

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9162074B2 (en) 2008-03-07 2015-10-20 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US11413468B2 (en) 2008-03-07 2022-08-16 Cameron Health, Inc. Accurate cardiac event detection in an implantable cardiac stimulus device
US10974058B2 (en) 2008-03-07 2021-04-13 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US10220219B2 (en) 2008-03-07 2019-03-05 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US9878172B2 (en) 2008-03-07 2018-01-30 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US9802056B2 (en) 2008-03-07 2017-10-31 Cameron Health, Inc. Accurate cardiac event detection in an implantable cardiac stimulus device
US8588896B2 (en) 2008-03-07 2013-11-19 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US9339662B2 (en) 2008-03-07 2016-05-17 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US8626280B2 (en) 2008-03-07 2014-01-07 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
CN102056646B (en) * 2008-03-07 2015-10-21 卡梅伦保健公司 Cardiac event accurately in implantable cardiac stimulus device detects
US8929977B2 (en) 2008-03-07 2015-01-06 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US9265432B2 (en) 2008-05-07 2016-02-23 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US10709379B2 (en) 2008-05-07 2020-07-14 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US8600489B2 (en) 2008-05-07 2013-12-03 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US8880161B2 (en) 2008-05-07 2014-11-04 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
US9763619B2 (en) 2008-05-07 2017-09-19 Cameron Health, Inc. Methods and devices for accurately classifying cardiac activity
CN101991410B (en) * 2009-08-31 2012-09-19 深圳市理邦精密仪器股份有限公司 Pulse rate searching and calculating method
CN101773388A (en) * 2010-02-26 2010-07-14 深圳和而泰智能控制股份有限公司 Method and device for accurately measuring blood pressure
CN101773388B (en) * 2010-02-26 2011-09-14 深圳和而泰智能控制股份有限公司 Device for accurately measuring blood pressure
CN101912259B (en) * 2010-08-06 2012-10-10 深圳瑞光康泰科技有限公司 Non-invasive blood pressure measuring device
CN101912259A (en) * 2010-08-06 2010-12-15 深圳瑞光康泰科技有限公司 Non-invasive blood pressure measuring device and measuring method thereof
CN102551708A (en) * 2010-10-14 2012-07-11 株式会社电装 Living body state monitor apparatus
CN105310673A (en) * 2014-07-30 2016-02-10 日本光电工业株式会社 Biological information measuring apparatus and biological information measuring method
US9554714B2 (en) 2014-08-14 2017-01-31 Cameron Health Inc. Use of detection profiles in an implantable medical device
US10758138B2 (en) 2014-08-14 2020-09-01 Cameron Health, Inc. Use of detection profiles in an implantable medical device
CN108882872A (en) * 2016-04-15 2018-11-23 欧姆龙株式会社 Biont information analytical equipment, Biont information analysis system, program and Biont information analysis method
WO2019227329A1 (en) * 2018-05-30 2019-12-05 深圳迈瑞生物医疗电子股份有限公司 Method for optimizing blood pressure measurement, and blood pressure measurement apparatus
CN112135559A (en) * 2018-05-30 2020-12-25 深圳迈瑞生物医疗电子股份有限公司 Optimization method for blood pressure measurement and blood pressure measurement device
CN109009051A (en) * 2018-06-26 2018-12-18 广州视源电子科技股份有限公司 Method for measuring heart rate, device, equipment and storage medium

Also Published As

Publication number Publication date
CN1985750B (en) 2011-03-23

Similar Documents

Publication Publication Date Title
CN1985750B (en) Pulse wave detecting method and device by means of cardiac symbol signal
CN102397064B (en) Continuous blood pressure measuring device
CN102488503B (en) Continuous blood pressure measurer
CN101810475B (en) Electronic auscultation sphygmomanometer based on combination of Korotkoff sound method and oscillometric method
CN100413464C (en) Method and apparatus for continuously measuring blood pressure
CN107865647B (en) Blood pressure detection device and method for calibrating blood pressure detection device
CA1187721A (en) Apparatus and method for measuring blood pressure
CN106691406A (en) Detection method of vascular elasticity and blood pressure based on single probe photoplethysmography pulse wave
US11006885B2 (en) Apparatus for determining blood pressure
CN104873186A (en) Wearable artery detection device and data processing method thereof
CN102429649A (en) Continuous blood pressure measuring device
CN201088579Y (en) Device for checking and evaluating arteriosclerosis
CN201157353Y (en) Detection apparatus for blood pressure and bloodstream parameter
US20120157791A1 (en) Adaptive time domain filtering for improved blood pressure estimation
CN1548005A (en) Blood pressure measuring device and method based on the pulse information of radial artery
CN104921715A (en) Multi-parameter vital sign measurement device
CN111973165B (en) Linear and nonlinear mixed non-invasive continuous blood pressure measuring system based on PPG
CN110881967A (en) Non-invasive multi-segment peripheral arterial vessel elastic function detection method and instrument thereof
CN110840428B (en) Noninvasive blood pressure estimation method based on one-dimensional U-Net network
CN102197998B (en) Use of the frequency spectrum of artifact in oscillometry
CN112155514A (en) Non-contact intraocular pressure measuring method based on pulse bioelectricity detection
CN101176661B (en) Device for measuring blood pressure of human body lower limbs anterior tibial artery and leg rear arterial
CN107995981B (en) Data processing method for blood pressure measuring device
CN113040738B (en) Blood pressure detecting device
CN1582845A (en) Blood pressure measuring method based on photoelectric plethysmographic signals with temperature compensation

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant