DE10120797A1 - Verfahren zur Analyse von Nukleinsäureketten - Google Patents

Verfahren zur Analyse von Nukleinsäureketten

Info

Publication number
DE10120797A1
DE10120797A1 DE10120797A DE10120797A DE10120797A1 DE 10120797 A1 DE10120797 A1 DE 10120797A1 DE 10120797 A DE10120797 A DE 10120797A DE 10120797 A DE10120797 A DE 10120797A DE 10120797 A1 DE10120797 A1 DE 10120797A1
Authority
DE
Germany
Prior art keywords
nts
nskfs
reaction
polymerase
sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE10120797A
Other languages
German (de)
English (en)
Other versions
DE10120797B4 (de
Inventor
Dmitri Tcherkassov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genovoxx GmbH
Original Assignee
Genovoxx GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genovoxx GmbH filed Critical Genovoxx GmbH
Priority to DE10120797A priority Critical patent/DE10120797B4/de
Priority to AU2002304705A priority patent/AU2002304705A1/en
Priority to EP02732680A priority patent/EP1381698A2/de
Priority to JP2002585662A priority patent/JP2004529650A/ja
Priority to PCT/EP2002/004659 priority patent/WO2002088382A2/de
Publication of DE10120797A1 publication Critical patent/DE10120797A1/de
Application granted granted Critical
Publication of DE10120797B4 publication Critical patent/DE10120797B4/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
DE10120797A 2001-04-27 2001-04-27 Verfahren zur Analyse von Nukleinsäureketten Expired - Lifetime DE10120797B4 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE10120797A DE10120797B4 (de) 2001-04-27 2001-04-27 Verfahren zur Analyse von Nukleinsäureketten
AU2002304705A AU2002304705A1 (en) 2001-04-27 2002-04-26 Method for analysing nucleic acid chains
EP02732680A EP1381698A2 (de) 2001-04-27 2002-04-26 Verfahren zur analyse von nukleinsäureketten
JP2002585662A JP2004529650A (ja) 2001-04-27 2002-04-26 核酸鎖の解析方法
PCT/EP2002/004659 WO2002088382A2 (de) 2001-04-27 2002-04-26 Verfahren zur analyse von nukleinsäureketten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10120797A DE10120797B4 (de) 2001-04-27 2001-04-27 Verfahren zur Analyse von Nukleinsäureketten

Publications (2)

Publication Number Publication Date
DE10120797A1 true DE10120797A1 (de) 2002-11-21
DE10120797B4 DE10120797B4 (de) 2005-12-22

Family

ID=7683014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10120797A Expired - Lifetime DE10120797B4 (de) 2001-04-27 2001-04-27 Verfahren zur Analyse von Nukleinsäureketten

Country Status (5)

Country Link
EP (1) EP1381698A2 (es)
JP (1) JP2004529650A (es)
AU (1) AU2002304705A1 (es)
DE (1) DE10120797B4 (es)
WO (1) WO2002088382A2 (es)

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DE10214395A1 (de) * 2002-03-30 2003-10-23 Dmitri Tcherkassov Verfahren zur Analyse von Einzelnukleotidpolymorphismen
DE10149786B4 (de) * 2001-10-09 2013-04-25 Dmitry Cherkasov Oberfläche für Untersuchungen aus Populationen von Einzelmolekülen

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US9708358B2 (en) 2000-10-06 2017-07-18 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
WO2003020968A2 (de) * 2001-08-29 2003-03-13 Genovoxx Gmbh Verfahren zur analyse von nukleinsäurekettensequenzen und der genexpression
US20050227231A1 (en) * 2001-10-04 2005-10-13 Dimitri Tcherkassov Device for sequencing nucleic acid molecules
GB0129012D0 (en) 2001-12-04 2002-01-23 Solexa Ltd Labelled nucleotides
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US7414116B2 (en) 2002-08-23 2008-08-19 Illumina Cambridge Limited Labelled nucleotides
AU2003259350A1 (en) 2002-08-23 2004-03-11 Solexa Limited Modified nucleotides for polynucleotide sequencing
US11008359B2 (en) 2002-08-23 2021-05-18 Illumina Cambridge Limited Labelled nucleotides
EP1725572B1 (de) 2003-11-05 2017-05-31 AGCT GmbH Makromolekulare nukleotidverbindungen und methoden zu deren anwendung
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
EP1716254B1 (en) 2004-02-19 2010-04-07 Helicos Biosciences Corporation Methods for analyzing polynucleotide sequences
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US20090291440A1 (en) * 2006-05-24 2009-11-26 Ken Hirano Method for synthesizing nucleic acid using dna polymerase beta and single molecule sequencing method
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WO2008069973A2 (en) 2006-12-01 2008-06-12 The Trustees Of Columbia University In The City Of New York Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
EP3431615A3 (en) 2007-10-19 2019-02-20 The Trustees of Columbia University in the City of New York Dna sequencing with non-fluorescent nucleotide reversible terminators cleavable label modified nucleotide terminators
EP2940029B1 (en) 2007-10-19 2023-11-29 The Trustees of Columbia University in the City of New York Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis
JP5146785B2 (ja) * 2008-07-24 2013-02-20 国立大学法人九州大学 酵素基質修飾ヌクレオシド三リン酸誘導体
JP4621926B2 (ja) * 2008-07-24 2011-02-02 国立大学法人九州大学 酵素基質修飾ヌクレオシド三リン酸、核酸プローブ、マルチラベル化核酸プローブ、マルチラベル化核酸プローブの製造方法および標的核酸の検出方法
US10174368B2 (en) 2009-09-10 2019-01-08 Centrillion Technology Holdings Corporation Methods and systems for sequencing long nucleic acids
WO2011032040A1 (en) 2009-09-10 2011-03-17 Centrillion Technology Holding Corporation Methods of targeted sequencing
WO2011050938A1 (de) 2009-10-26 2011-05-05 Genovoxx Gmbh Konjugate von nukleotiden und methoden zu deren anwendung
ES2821500T3 (es) 2009-11-06 2021-04-26 Univ Leland Stanford Junior Diagnóstico no invasivo del rechazo de injertos en pacientes con trasplante de órganos
JP5704481B2 (ja) * 2010-01-22 2015-04-22 国立大学法人九州大学 核酸検出用キット
US9646134B2 (en) 2010-05-25 2017-05-09 The Regents Of The University Of California Bambam: parallel comparative analysis of high-throughput sequencing data
EP2577538A1 (en) 2010-05-25 2013-04-10 The Regents of the University of California Bambam: parallel comparative analysis of high-throughput sequencing data
ES2687761T3 (es) 2011-01-31 2018-10-29 F. Hoffmann-La Roche Ag Métodos de identificación de múltiples epítopos en células
US20120252682A1 (en) 2011-04-01 2012-10-04 Maples Corporate Services Limited Methods and systems for sequencing nucleic acids
US9994894B2 (en) 2011-04-27 2018-06-12 Agct Gmbh Method and components for detecting nucleic acid chains
DE102012008759A1 (de) 2011-05-04 2012-11-08 Genovoxx Gmbh Nukleosid-Triphosphat-Konjugate und Methoden zu deren Anwendung
WO2013070634A1 (en) 2011-11-07 2013-05-16 Ingenuity Systems, Inc. Methods and systems for identification of causal genomic variants
EP2882868B1 (en) 2012-08-08 2019-07-31 H. Hoffnabb-La Roche Ag Increasing dynamic range for identifying multiple epitopes in cells
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
CN108624668B (zh) 2013-02-01 2022-12-02 加利福尼亚大学董事会 用于基因组组装及单体型定相的方法
KR102230831B1 (ko) 2013-03-15 2021-03-22 일루미나 케임브리지 리미티드 변형된 뉴클레오사이드 또는 뉴클레오타이드
CN105189748B (zh) 2013-03-15 2021-06-08 血统生物科学公司 测序免疫组库的方法
WO2014144883A1 (en) 2013-03-15 2014-09-18 The Trustees Of Columbia University In The City Of New York Raman cluster tagged molecules for biological imaging
CN103484106B (zh) * 2013-09-05 2015-08-19 上海交通大学 四色荧光标记可逆终端及其在dna测序中的用途
BR112016010095A2 (pt) 2013-11-07 2017-09-12 Univ Leland Stanford Junior ácidos nucleicos de célula livre para a ánalise de microbioma humano e componentes do mesmos.
US11091758B2 (en) 2013-12-11 2021-08-17 The Regents Of The University Of California Methods for labeling DNAa fragments to reconstruct physical linkage and phase
US10526641B2 (en) 2014-08-01 2020-01-07 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
GB201414098D0 (en) 2014-08-08 2014-09-24 Illumina Cambridge Ltd Modified nucleotide linkers
JP6777966B2 (ja) 2015-02-17 2020-10-28 ダブテイル ゲノミクス エルエルシー 核酸配列アセンブリ
GB2554572B (en) 2015-03-26 2021-06-23 Dovetail Genomics Llc Physical linkage preservation in DNA storage
JP7300831B2 (ja) 2015-10-19 2023-06-30 ダブテイル ゲノミクス エルエルシー ゲノムアセンブリ、ハプロタイプフェージング、および標的に依存しない核酸検出のための方法
JP7441003B2 (ja) 2016-02-23 2024-02-29 ダブテイル ゲノミクス エルエルシー ゲノムアセンブリのためのフェージングされたリードセットの生成とハプロタイプフェージング
SG11201810088SA (en) 2016-05-13 2018-12-28 Dovetail Genomics Llc Recovering long-range linkage information from preserved samples
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CA3068273A1 (en) 2017-06-21 2018-12-27 Bluedot Llc Systems and methods for identification of nucleic acids in a sample
WO2019060716A1 (en) 2017-09-25 2019-03-28 Freenome Holdings, Inc. SAMPLE EXTRACTION METHODS AND SYSTEMS
AU2019214956A1 (en) 2018-01-31 2020-08-27 Dovetail Genomics, Llc Sample prep for DNA linkage recovery
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10149786B4 (de) * 2001-10-09 2013-04-25 Dmitry Cherkasov Oberfläche für Untersuchungen aus Populationen von Einzelmolekülen
DE10214395A1 (de) * 2002-03-30 2003-10-23 Dmitri Tcherkassov Verfahren zur Analyse von Einzelnukleotidpolymorphismen

Also Published As

Publication number Publication date
WO2002088382A3 (de) 2003-08-28
AU2002304705A1 (en) 2002-11-11
WO2002088382A2 (de) 2002-11-07
JP2004529650A (ja) 2004-09-30
DE10120797B4 (de) 2005-12-22
EP1381698A2 (de) 2004-01-21

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