DE10196608T1 - Verfahren und Kits für den Nachweis von Proteinkinasen - Google Patents

Verfahren und Kits für den Nachweis von Proteinkinasen

Info

Publication number
DE10196608T1
DE10196608T1 DE10196608T DE10196608T DE10196608T1 DE 10196608 T1 DE10196608 T1 DE 10196608T1 DE 10196608 T DE10196608 T DE 10196608T DE 10196608 T DE10196608 T DE 10196608T DE 10196608 T1 DE10196608 T1 DE 10196608T1
Authority
DE
Germany
Prior art keywords
atp
tested
protein kinase
kits
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE10196608T
Other languages
English (en)
Inventor
Sharon Patricia Mary Crouch
Kavin John Slater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambrex Bio Science Nottingham Ltd
Original Assignee
Cambrex Bio Science Nottingham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9905234&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE10196608(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cambrex Bio Science Nottingham Ltd filed Critical Cambrex Bio Science Nottingham Ltd
Publication of DE10196608T1 publication Critical patent/DE10196608T1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
DE10196608T 2000-12-15 2001-12-13 Verfahren und Kits für den Nachweis von Proteinkinasen Ceased DE10196608T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0030727.2A GB0030727D0 (en) 2000-12-15 2000-12-15 Methods and kits for detecting kinase activity
PCT/GB2001/005506 WO2002048390A2 (en) 2000-12-15 2001-12-13 Methods and kits for detecting protein kinases

Publications (1)

Publication Number Publication Date
DE10196608T1 true DE10196608T1 (de) 2003-07-31

Family

ID=9905234

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10196608T Ceased DE10196608T1 (de) 2000-12-15 2001-12-13 Verfahren und Kits für den Nachweis von Proteinkinasen
DE60115090T Expired - Lifetime DE60115090T2 (de) 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60115090T Expired - Lifetime DE60115090T2 (de) 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität

Country Status (12)

Country Link
US (3) US6599711B2 (de)
EP (1) EP1341928B1 (de)
JP (1) JP3854927B2 (de)
AT (1) ATE310101T1 (de)
AU (1) AU2002222193A1 (de)
CA (1) CA2431274C (de)
CH (1) CH694096A5 (de)
DE (2) DE10196608T1 (de)
DK (1) DK1341928T3 (de)
ES (1) ES2256165T3 (de)
GB (2) GB0030727D0 (de)
WO (1) WO2002048390A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006059881A1 (de) * 2006-12-19 2008-07-03 Sanofi-Aventis Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0030727D0 (en) * 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity
CA2497476A1 (en) 2002-09-06 2004-03-18 Promega Corporation Method for detecting atp-dependent transferase enzymatic activity
US7799526B2 (en) 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
EP2325328B1 (de) 2002-12-23 2014-02-12 Promega Corporation Verbesserte luciferase-assays
EP1592813B1 (de) * 2003-01-30 2012-12-26 BellBrook Labs, LLC Testverfahren für gruppenübertragungsreaktionen
US7355010B2 (en) * 2003-01-30 2008-04-08 Bellbrook Labs, Llc Assay method for group transfer reactions
US8088897B2 (en) * 2003-01-30 2012-01-03 BellBrook Labs, Inc. Assay method for group transfer reactions
US7378505B2 (en) * 2003-01-30 2008-05-27 Bellbrook Labs Llc Assay method for group transfer reactions
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
KR20060127043A (ko) * 2003-12-22 2006-12-11 알콘, 인코퍼레이티드 녹내장성 망막병증 및 시각신경병증의 치료용 약제
TW200526224A (en) * 2003-12-22 2005-08-16 Alcon Inc Short form c-Maf transcription factor antagonists for treatment of glaucoma
MXPA06006862A (es) * 2003-12-22 2007-01-26 Alcon Inc Agentes para el tratamiento de la retinopatia diabetica y formacion de drusen en degeneracion macular.
EP1704406A4 (de) 2004-01-16 2008-05-28 Mds Pharma Services Adp-nachweissystem auf fluoreszenzbasis
CN1918305B (zh) * 2004-02-09 2010-12-01 扶桑药品工业株式会社 核酸检测方法及其应用
US20080096238A1 (en) * 2004-03-30 2008-04-24 Alcon, Inc. High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio
WO2005102345A1 (en) * 2004-03-30 2005-11-03 Alcon, Inc. Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
US20060115870A1 (en) * 2004-03-30 2006-06-01 Alcon, Inc. High throughput assay for human Rho kinase activity
WO2006085972A2 (en) * 2004-07-02 2006-08-17 Promega Corporation Compositions and processes for the extraction and detection of microbial atp
WO2006055453A1 (en) * 2004-11-18 2006-05-26 Saladax Biomedical Inc. Enzymatic measurement of imatinib mesylate
US7338775B1 (en) 2005-02-09 2008-03-04 Myriad Genetics, Inc. Enzyme assay and use thereof
US20060234323A1 (en) * 2005-04-18 2006-10-19 Cali James J Luminescent ATP detection with extended linearity
US7348159B2 (en) * 2005-04-20 2008-03-25 Boehringer Ingelheim International Gmbh Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S
WO2007050407A1 (en) * 2005-10-21 2007-05-03 Deere & Company Systems and methods for switching between autonomous and manual operation of a vehicle
WO2007093049A1 (en) 2006-02-13 2007-08-23 Olga Ornatsky Kinase and phosphatase assays conducted by elemental analysis
EP3260863B1 (de) * 2006-05-27 2021-03-10 Fluidigm Canada Inc. Verfahren zur multiplexanalyse von zwei oder mehr analyten
KR100746961B1 (ko) 2006-07-31 2007-08-07 한국과학기술연구원 단백질 키나아제 ａ 검출용 바이오 센서, 및 이를 포함하는키트
US20080057531A1 (en) * 2006-08-07 2008-03-06 Oregon Health And Science University Systems, kits, and methods for detecting cariogenic bacteria and assessing risk of dental caries
US7977043B2 (en) * 2006-11-10 2011-07-12 Boehringer Ingelheim International Gmbh Assays useful in determining CD38 inhibition
US8183007B2 (en) * 2008-07-22 2012-05-22 Promega Corporation ADP detection based methods using adenylate cyclase and bioluminescence
WO2012036675A1 (en) * 2010-09-14 2012-03-22 Research And Diagnostic Systems, Inc. Phosphatase coupled kinase assay
GB201017721D0 (en) * 2010-10-20 2010-12-01 Queen Mary & Westfield College Method
NL2013366B1 (en) 2014-08-26 2016-09-23 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Adenylation enzyme inhibitors.
EP3204509B1 (de) 2014-10-08 2019-07-10 Promega Corporation Biolumineszierender test zum nachweis von succinat
KR20180016513A (ko) * 2015-07-06 2018-02-14 후지필름 가부시키가이샤 혈액 검사 키트, 및 그것을 이용한 분석 방법
KR101788096B1 (ko) * 2016-04-12 2017-10-19 재단법인 한국파스퇴르연구소 티아민 모노포스페이트 키나아제를 이용한 항균물질의 스크리닝 키트 및 스크리닝 방법
JP7414029B2 (ja) 2021-02-26 2024-01-16 横河電機株式会社 測定方法及び測定システム

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE428379B (sv) * 1978-05-31 1983-06-27 Lkb Produkter Ab Bioluminiscens bestemning av atp och reagens herfor
DE2828658C3 (de) * 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
DE2908054A1 (de) 1979-03-02 1980-09-11 Boehringer Mannheim Gmbh Verfahren und reagenz zur bestimmung der creatinkinase
SE7905852L (sv) * 1979-07-04 1981-01-05 Lkb Produkter Ab Forfarande for bestemning av kreatinkinas
GB2055200B (en) * 1979-07-24 1984-05-02 Kolehmainen S Luminescent assays with enzymatic cycling enhancement of the sensitivity of bioluminescent and chemi
US5583024A (en) 1985-12-02 1996-12-10 The Regents Of The University Of California Recombinant expression of Coleoptera luciferase
DE8533854U1 (de) * 1985-12-02 1986-02-27 Lewandoske, Herbert, 8620 Lichtenfels Sitzmöbel, insbesondere Sofa (und Sessel) mit abklappbaren Armlehnen
US4968613A (en) 1987-07-29 1990-11-06 Kikkoman Corporation Luciferase gene and novel recombinant DNA as well as a method of producing luciferase
US5219737A (en) 1990-03-27 1993-06-15 Kikkoman Corporation Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase
US5374534A (en) 1990-07-19 1994-12-20 Charm Sciences, Inc. Method of preparing D-luciferin derivatives
US5648232A (en) * 1993-01-21 1997-07-15 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Microbiological best method and reagents
GB9301118D0 (en) 1993-01-21 1993-03-10 Secr Defence Enzyme linked assays
ES2301160T3 (es) 1994-01-03 2008-06-16 Promega Corporation Luciferasas mutantes.
DK0804587T3 (da) 1995-01-20 2004-10-11 Secr Defence Mutantluciferaser
JP3409962B2 (ja) * 1996-03-04 2003-05-26 キッコーマン株式会社 生物発光試薬及びその試薬を用いたアデノシンリン酸エステルの定量法並びにその試薬を用いたａｔｐ変換反応系に関与する物質の定量法
US5759795A (en) * 1996-03-08 1998-06-02 Schering Corporation Assay for determining inhibitors of ATPase
US5925558A (en) * 1996-07-16 1999-07-20 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
US5759787A (en) * 1996-08-26 1998-06-02 Tularik Inc. Kinase assay
GB9626932D0 (en) 1996-12-24 1997-02-12 Lumitech Limited Assay methods and kits therefor
GB9707486D0 (en) 1997-04-11 1997-05-28 Secr Defence Enzyme assays
US6310060B1 (en) * 1998-06-24 2001-10-30 Warner-Lambert Company 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
EP1020524B1 (de) 1997-07-08 2007-04-18 Kikkoman Corporation Mutiertes bioluminiszenz-protein und verfahren für seine herstellung.
US6074859A (en) 1997-07-08 2000-06-13 Kikkoman Corporation Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein
ATE330025T1 (de) 1998-01-21 2006-07-15 Secr Defence Test für antibiotikaresistenz
GB9803156D0 (en) 1998-02-13 1998-04-08 Celsis Int Plc Assay
NL1010224C2 (nl) 1998-09-30 2000-03-31 Packard Biosciene B V Werkwijze voor het detecteren van ATP.
DE19901427C1 (de) * 1999-01-18 2000-08-10 Walter Knoll Gmbh & Co Kg Sitz Sitzmöbel
GB9911095D0 (en) 1999-05-13 1999-07-14 Secr Defence Microbiological test method and reagents
GB0030727D0 (en) * 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006059881A1 (de) * 2006-12-19 2008-07-03 Sanofi-Aventis Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse

Also Published As

Publication number Publication date
JP2004518422A (ja) 2004-06-24
ES2256165T3 (es) 2006-07-16
EP1341928A2 (de) 2003-09-10
DK1341928T3 (da) 2006-03-27
GB0030727D0 (en) 2001-01-31
EP1341928B1 (de) 2005-11-16
CA2431274C (en) 2011-05-17
US20020172991A1 (en) 2002-11-21
AU2002222193A1 (en) 2002-06-24
DE60115090T2 (de) 2006-07-13
US6599711B2 (en) 2003-07-29
US20040077030A1 (en) 2004-04-22
ATE310101T1 (de) 2005-12-15
CA2431274A1 (en) 2002-06-20
US20040253658A1 (en) 2004-12-16
GB0129889D0 (en) 2002-02-06
GB2375171B (en) 2003-03-12
CH694096A5 (de) 2004-07-15
JP3854927B2 (ja) 2006-12-06
WO2002048390A2 (en) 2002-06-20
WO2002048390A3 (en) 2003-06-26
GB2375171A (en) 2002-11-06
DE60115090D1 (de) 2005-12-22
US6911319B2 (en) 2005-06-28

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