DE10318026C5 - Cryostat with lighting device - Google Patents
Cryostat with lighting device Download PDFInfo
- Publication number
- DE10318026C5 DE10318026C5 DE10318026.5A DE10318026A DE10318026C5 DE 10318026 C5 DE10318026 C5 DE 10318026C5 DE 10318026 A DE10318026 A DE 10318026A DE 10318026 C5 DE10318026 C5 DE 10318026C5
- Authority
- DE
- Germany
- Prior art keywords
- cryostat
- lighting
- chamber
- lighting modules
- individual
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D27/00—Lighting arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/42—Low-temperature sample treatment, e.g. cryofixation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
- G01N2001/068—Illumination means
Abstract
Kryostat (1) mit einer Kryostatkammer (2) in der ein Mikrotom (3) zum Schneiden von gefrorenen Präparaten angeordnet ist und mit einer Beleuchtungseinrichtung (4) zum Ausleuchten der Kryostatkammer (2), dadurch gekennzeichnet, dass die Beleuchtungseinrichtung (4) mehrere zu einem Beleuchtungsmodul (6) zusammengefasste LEDs (5) aufweist und dass die elektrischen Kontakte der LEDs (5) des Beleuchtungsmoduls (6) durch einen Spritzwasserschutz (12) geschützt sind, wobei ein Beleuchtungsmodul oder mehrere Beleuchtungsmodule vorhanden sind, wobei eine Schaltungsanordnung (10) zum Schalten einzelner und/oder mehrerer Beleuchtungsmodule (6) vorhanden ist und am Kryostat (1) ein Schalter (11) angeordnet und mit der Schaltungsanordnung (10) elektrisch verbunden ist und der Schalter (11) beim Öffnen und/oder Schließen der Kryostatkammer (3) einzelne und/oder mehrere Beleuchtungsmodule (6) automatisch schaltet.Cryostat (1) with a cryostat chamber (2) in which a microtome (3) for cutting frozen preparations is arranged and with a lighting device (4) for illuminating the cryostat chamber (2), characterized in that the illumination device (4) to several a lighting module (6) summarized LEDs (5) and that the electrical contacts of the LEDs (5) of the lighting module (6) are protected by a splash guard (12), wherein one lighting module or more lighting modules are present, wherein a circuit arrangement (10) for switching individual and / or a plurality of lighting modules (6) is present and at the cryostat (1) a switch (11) arranged and electrically connected to the circuit arrangement (10) and the switch (11) when opening and / or closing the cryostat chamber ( 3) individual and / or multiple lighting modules (6) automatically switches.
Description
Die Erfindung betrifft einen Kryostat mit einer Kryostatkammer in der ein Mikrotom zum Schneiden von gefrorenen Präparaten angeordnet ist, gemäß dem Oberbegriff des Patentanspruchs 1.The invention relates to a cryostat with a cryostat chamber in which a microtome for cutting frozen preparations is arranged, according to the preamble of
Derartige Kryostate werden verwendet, um mit einem Mikrotom gefrorene Präparate für eine anschließende Betrachtung mit einem Mikroskop zu schneiden. Die zu schneidenden Präparate werden auf eine bestimmte vorgegebene Temperatur gekühlt werden. Die Temperaturen liegen hierbei in der Regel zwischen –10°C und –50°C. Um die Temperaturkonstanz zu gewährleisten, werden die Mikrotome in aufwendig gekapselten Kryostatkammern angeordnet und diese entsprechend gekühlt.Such cryostats are used to cut microtome-frozen preparations for subsequent viewing with a microscope. The preparations to be cut are cooled to a certain predetermined temperature. The temperatures are usually between -10 ° C and -50 ° C. In order to ensure the temperature stability, the microtomes are arranged in elaborately encapsulated Kryostatkammern and these cooled accordingly.
Um ein sicheres Arbeiten zu gewährleisten, wird die Kryostatkammer mit Lampen beleuchtet. Dies hat jedoch den Nachteil, dass diese Lichtquellen Wärme erzeugen und so die für den Schnitt des Präparats entscheidende Temperaturkonstanz gefährdet ist.To ensure safe working, the cryostat chamber is illuminated with lamps. However, this has the disadvantage that these light sources generate heat and thus the decisive for the cut of the preparation temperature stability is compromised.
Außerdem hat es sich herausgestellt, dass sich die recht groß dimensionierten Lichtquellen nur schlecht reinigen lassen.In addition, it has been found that the fairly large-sized light sources can only be cleaned poorly.
Aus der
Die
Es ist daher Aufgabe der vorliegenden Erfindung, die Beleuchtung der Kryostatkammer so zu verbessern, dass eine höhere Temperaturkonstanz innerhalb der Kammer gegeben ist.It is therefore an object of the present invention to improve the illumination of the cryostat chamber so that a higher temperature stability is given within the chamber.
Diese Aufgabe wird erfindungsgemäß durch die im kennzeichnenden Teil des Patentanspruches 1 angegebenen Merkmale gelöst. Weitere vorteilhafte Weiterbildungen sind Gegenstand der Unteransprüche.This object is achieved by the features specified in the characterizing part of
Die Erfindung zeichnet sich dadurch aus, dass die Beleuchtungseinrichtung als Lichtquelle mehrere LEDs, vorzugsweise Weißlicht-LEDs, aufweist. Mit den LEDs wird eine kompakte Bauform, eine sehr geringe Wärmeabstrahlung und eine gute Reinigungs- und Desinfektionsmöglichkeit erreicht. Außerdem lassen sich die LEDs durch ihre Raumform auch sehr gut gegen Spritzwasser schützen.The invention is characterized in that the illumination device has a plurality of LEDs, preferably white light LEDs, as the light source. With the LEDs, a compact design, a very low heat radiation and a good cleaning and disinfection option is achieved. In addition, the LEDs can also protect very well against splashing water by their spatial form.
Mehrere LEDs sind zu einem Beleuchtungsmodul zusammengefasst. Damit wird eine erhöhte Leuchtdichte bei einer kompakten Bauform erreicht. Ferner lassen sich so auch die elektrischen Kontakte der LEDs sehr einfach gegen Feuchtigkeit bzw. Spritzwasser schützen.Several LEDs are combined to form a lighting module. This achieves increased luminance in a compact design. Furthermore, the electrical contacts of the LEDs can also be very easily protected against moisture or splash water.
In einer Weiterbildung weist das Beleuchtungsmodul ein Gehäuse mit einem Steckeranschluss zur Stromversorgung auf. Damit wird erreicht, dass das Beleuchtungsmodul über den Steckeranschluss austauschbar in der Kryostatkammer angeordnet werden kann. So können, je nach Bedarf, einzelne oder mehrere Beleuchtungsmodule in vorbereitete Steckeraufnahmen in der Kryostatkammer austauschbar angeordnet werden.In a further development, the lighting module has a housing with a plug connection for the power supply. This ensures that the lighting module can be arranged interchangeably in the cryostat chamber via the plug connection. Thus, as needed, one or more lighting modules can be interchangeably arranged in prepared plug receptacles in the cryostat chamber.
In einer weiteren Ausgestaltung der Erfindung sind mehrere Beleuchtungsmodule elektrisch mit einer gemeinsamen Stromversorgung verbunden. Diese Stromversorgung ist vorzugsweise außerhalb der Kryostatkammer vorgesehen, so dass neben einem minimierten Aufwand hier auch eine reduzierte Wärmeentwicklung realisiert ist.In a further embodiment of the invention, a plurality of lighting modules are electrically connected to a common power supply. This power supply is preferably provided outside the cryostat chamber, so that in addition to a minimized effort here also a reduced heat development is realized.
Ferner ist eine Schaltungsanordnung zum An- und Abschalten einzelner und/oder mehrerer Beleuchtungsmodule vorgesehen. Je nach Anwendung können so einzelne Bereiche innerhalb der Kryostatkammer beleuchtet werden.Furthermore, a circuit arrangement for switching on and off of individual and / or a plurality of lighting modules is provided. Depending on the application, individual areas within the cryostat chamber can be illuminated.
In einer vorteilhaften Weiterbildung hat die Schaltungsanordnung zusätzlich die Funktion eines Dimmers für einzelner und/oder mehrerer Beleuchtungsmodule.In an advantageous development, the circuit arrangement additionally has the function of a dimmer for individual and / or multiple lighting modules.
Dadurch ist ebenfalls eine individuelle Ausleuchtung der Kryostatkammer möglich.As a result, an individual illumination of the cryostat chamber is also possible.
Ferner ist am Kryostat ein Schalter angeordnet und mit der Schaltungsanordnung elektrisch verbunden, wobei der Schalter beim Öffnen und/oder Schließen der Kryostatkammer einzelne und/oder mehrere Beleuchtungsmodule automatisch schaltet. Mit dieser Funktion wird erreicht, dass beim Öffnen der Deckels oder der Scheibe durch eine Bedienperson automatisch das Beleuchtungslicht innerhalb der Kammer gesteuert wird. So ist es beispielsweise möglich, beim Öffnen immer auf optimale Beleuchtung zu Schalten und beim Schließen einzelne Beleuchtungsmodule auszuschalten oder zu dimmen. So erscheint es sinnvoll, bei geschlossener Kryostatkammer nur den Probenhalter und/oder das Schneidmesser des Mikrotoms zu beleuchten.Furthermore, a switch is arranged on the cryostat and electrically connected to the circuit arrangement, the switch automatically switching individual and / or multiple lighting modules when opening and / or closing the cryostat chamber. With this function it is achieved that when opening the lid or the disc by an operator automatically the illumination light is controlled within the chamber. For example, it is possible to always switch to optimal lighting when opening and to switch off or dim individual lighting modules when closing them. So it makes sense to illuminate with closed cryostat chamber only the sample holder and / or the cutting blade of the microtome.
Den LEDs des Beleuchtungsmoduls ist ein Spritzwasserschutz zugeordnet. Vorteilhaft kann das Beleuchtungsmodul mit einer Dichtung zur Kapselung der elektrischen LED Kontakte ausgestattet sein.The LEDs of the lighting module is assigned a splash protection. Advantageously, the lighting module can be equipped with a seal for encapsulating the electrical LED contacts.
Die Erfindung wird anhand eines Ausführungsbeispiels mit Hilfe der schematischen Zeichnungen näher erläutert. Es zeigen:The invention will be explained in more detail using an exemplary embodiment with the aid of the schematic drawings. Show it:
Die
Über die Schaltungsanordnung
Die
Die
Die
Claims (5)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10318026.5A DE10318026C5 (en) | 2003-04-19 | 2003-04-19 | Cryostat with lighting device |
DE20321622U DE20321622U1 (en) | 2003-04-19 | 2003-04-19 | Lighting device in a cryostat |
GB0403255A GB2400645B (en) | 2003-04-19 | 2004-02-13 | Illumination device in a cryostat |
US10/824,211 US20040206093A1 (en) | 2003-04-19 | 2004-04-14 | Illumination device in a cryostat |
JP2004121043A JP2004317515A (en) | 2003-04-19 | 2004-04-16 | Cryostat having lighting device |
CNB2004100368306A CN100498271C (en) | 2003-04-19 | 2004-04-19 | Low temperature thermostat |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10318026.5A DE10318026C5 (en) | 2003-04-19 | 2003-04-19 | Cryostat with lighting device |
Publications (3)
Publication Number | Publication Date |
---|---|
DE10318026A1 DE10318026A1 (en) | 2004-11-04 |
DE10318026B4 DE10318026B4 (en) | 2010-05-27 |
DE10318026C5 true DE10318026C5 (en) | 2015-11-12 |
Family
ID=32010540
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10318026.5A Expired - Fee Related DE10318026C5 (en) | 2003-04-19 | 2003-04-19 | Cryostat with lighting device |
DE20321622U Expired - Lifetime DE20321622U1 (en) | 2003-04-19 | 2003-04-19 | Lighting device in a cryostat |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE20321622U Expired - Lifetime DE20321622U1 (en) | 2003-04-19 | 2003-04-19 | Lighting device in a cryostat |
Country Status (5)
Country | Link |
---|---|
US (1) | US20040206093A1 (en) |
JP (1) | JP2004317515A (en) |
CN (1) | CN100498271C (en) |
DE (2) | DE10318026C5 (en) |
GB (1) | GB2400645B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4840763B2 (en) * | 2006-01-18 | 2011-12-21 | セイコーインスツル株式会社 | Automatic thin section preparation apparatus and automatic thin section preparation apparatus |
DE102009061068B4 (en) | 2009-04-17 | 2015-05-07 | Leica Biosystems Nussloch Gmbh | Method for producing microscopic thin sections of tissue samples |
CN103037775B (en) * | 2010-03-31 | 2016-11-23 | 海林生命产品公司 | New ovulation predictor device |
DE102011002443B4 (en) * | 2011-01-04 | 2013-08-29 | Leica Biosystems Nussloch Gmbh | Cryostat with lighting device |
DE102012215859A1 (en) | 2012-09-06 | 2014-03-06 | Leica Biosystems Nussloch Gmbh | Processing device for processing tissue samples with a reader device for user identification units |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3615713C1 (en) * | 1986-05-09 | 1987-09-03 | Bernhard Dr Wolf | Microtome |
WO1988002851A2 (en) * | 1986-10-14 | 1988-04-21 | Hellmuth Sitte | Refrigerated chamber for obtaining thin slices at low temperature |
DE19527168A1 (en) * | 1995-07-25 | 1997-01-30 | Robert Bodenstedt Elekronik | Illuminating device for bicycle rear light |
DE19908404A1 (en) * | 1999-02-26 | 2000-09-07 | Airsigna Gmbh & Co Kg | Inside illumination for air-, water- craft etc. with several light sources, such as a LEDs or laser diodes, of long service life |
US6152590A (en) * | 1998-02-13 | 2000-11-28 | Donnelly Hohe Gmbh & Co. Kg | Lighting device for motor vehicles |
DE10013056A1 (en) * | 2000-03-19 | 2001-09-20 | Osram Opto Semiconductors Gmbh | LED light source module has optical device that changes light emitted by LED arrangement so that light density distribution on illuminated surface is uniform |
DE10051159A1 (en) * | 2000-10-16 | 2002-05-02 | Osram Opto Semiconductors Gmbh | LED module, e.g. White light source |
US6472823B2 (en) * | 2001-03-07 | 2002-10-29 | Star Reach Corporation | LED tubular lighting device and control device |
US20030002282A1 (en) * | 2001-06-29 | 2003-01-02 | Jagath Swaris | Modular mounting arrangement and method for light emitting diodes |
DE10147986A1 (en) * | 2001-09-28 | 2003-04-10 | Osram Opto Semiconductors Gmbh | Manufacturing surface mountable light emitting diode light source involves bending leadframe reflector section into shape of reflector before or after mounting LED chip |
DE10250877A1 (en) * | 2002-10-31 | 2004-05-19 | Osram Opto Semiconductors Gmbh | Light emitting semiconductor element and production process for motor vehicle lights and light coupling, has main radiating direction at between zero and ninety degrees to the mounting plane |
DE10303969A1 (en) * | 2003-01-31 | 2004-08-19 | Osram Opto Semiconductors Gmbh | Light emitting diode carrier for display has matrix of devices covered by a clear protective foil |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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GB1518792A (en) * | 1975-11-04 | 1978-07-26 | South London Elect Equip | Cryostats |
DE2906153C2 (en) * | 1979-02-17 | 1984-10-31 | C. Reichert Optische Werke Ag, Wien | Cooling chamber for holding objects to be processed, in particular biological objects |
DE8812708U1 (en) * | 1988-10-10 | 1989-01-05 | Cambridge Instruments Gmbh, 6907 Nussloch, De | |
DE19803966B4 (en) * | 1997-03-07 | 2006-05-11 | Microm International Gmbh | Suction device for cutting waste in a cryostat microtome and cryostat microtome |
EP0971186B1 (en) * | 1998-07-08 | 2003-08-20 | Liebherr-Hausgeräte Ochsenhausen GmbH | Interior lighting for refrigerator |
DE29914037U1 (en) * | 1999-08-11 | 2000-12-28 | Diehl Ako Stiftung Gmbh & Co | Indoor lighting for household appliances |
JP2001221951A (en) * | 1999-11-29 | 2001-08-17 | Olympus Optical Co Ltd | Microscope |
DE19961787A1 (en) * | 1999-12-21 | 2001-06-28 | Bsh Bosch Siemens Hausgeraete | Refrigeration device has illumination device with illumination body between transparent, plate-like cover layer and wall with heat resistant section in illumination body radiation region |
CN1201636C (en) * | 2000-02-03 | 2005-05-11 | 皇家菲利浦电子有限公司 | Supply assembly for LED lighting module |
CH697261B1 (en) * | 2000-09-26 | 2008-07-31 | Lisa Lux Gmbh | Lighting for refrigeration units. |
CA2336497A1 (en) * | 2000-12-20 | 2002-06-20 | Daniel Chevalier | Lighting device |
US6481219B2 (en) * | 2001-03-30 | 2002-11-19 | Sakura Finetek U.S.A., Inc. | Disinfection system and method of using same |
CZ12316U1 (en) * | 2002-04-25 | 2002-06-10 | K.T.-Kalttech, S.R.O. | Lighting device for refrigerators, particularly for thermoelectric refrigerators |
US6851820B2 (en) * | 2002-06-26 | 2005-02-08 | Weber-Stephen Products Company | Barbecue grill light |
-
2003
- 2003-04-19 DE DE10318026.5A patent/DE10318026C5/en not_active Expired - Fee Related
- 2003-04-19 DE DE20321622U patent/DE20321622U1/en not_active Expired - Lifetime
-
2004
- 2004-02-13 GB GB0403255A patent/GB2400645B/en not_active Expired - Fee Related
- 2004-04-14 US US10/824,211 patent/US20040206093A1/en not_active Abandoned
- 2004-04-16 JP JP2004121043A patent/JP2004317515A/en active Pending
- 2004-04-19 CN CNB2004100368306A patent/CN100498271C/en not_active Expired - Fee Related
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3615713C1 (en) * | 1986-05-09 | 1987-09-03 | Bernhard Dr Wolf | Microtome |
WO1988002851A2 (en) * | 1986-10-14 | 1988-04-21 | Hellmuth Sitte | Refrigerated chamber for obtaining thin slices at low temperature |
DE19527168A1 (en) * | 1995-07-25 | 1997-01-30 | Robert Bodenstedt Elekronik | Illuminating device for bicycle rear light |
US6152590A (en) * | 1998-02-13 | 2000-11-28 | Donnelly Hohe Gmbh & Co. Kg | Lighting device for motor vehicles |
DE19908404A1 (en) * | 1999-02-26 | 2000-09-07 | Airsigna Gmbh & Co Kg | Inside illumination for air-, water- craft etc. with several light sources, such as a LEDs or laser diodes, of long service life |
DE10013056A1 (en) * | 2000-03-19 | 2001-09-20 | Osram Opto Semiconductors Gmbh | LED light source module has optical device that changes light emitted by LED arrangement so that light density distribution on illuminated surface is uniform |
DE10051159A1 (en) * | 2000-10-16 | 2002-05-02 | Osram Opto Semiconductors Gmbh | LED module, e.g. White light source |
US6472823B2 (en) * | 2001-03-07 | 2002-10-29 | Star Reach Corporation | LED tubular lighting device and control device |
US20030002282A1 (en) * | 2001-06-29 | 2003-01-02 | Jagath Swaris | Modular mounting arrangement and method for light emitting diodes |
DE10147986A1 (en) * | 2001-09-28 | 2003-04-10 | Osram Opto Semiconductors Gmbh | Manufacturing surface mountable light emitting diode light source involves bending leadframe reflector section into shape of reflector before or after mounting LED chip |
DE10250877A1 (en) * | 2002-10-31 | 2004-05-19 | Osram Opto Semiconductors Gmbh | Light emitting semiconductor element and production process for motor vehicle lights and light coupling, has main radiating direction at between zero and ninety degrees to the mounting plane |
DE10303969A1 (en) * | 2003-01-31 | 2004-08-19 | Osram Opto Semiconductors Gmbh | Light emitting diode carrier for display has matrix of devices covered by a clear protective foil |
Also Published As
Publication number | Publication date |
---|---|
DE20321622U1 (en) | 2008-07-17 |
JP2004317515A (en) | 2004-11-11 |
GB2400645B (en) | 2005-06-29 |
GB2400645A (en) | 2004-10-20 |
GB0403255D0 (en) | 2004-03-17 |
CN1538160A (en) | 2004-10-20 |
CN100498271C (en) | 2009-06-10 |
US20040206093A1 (en) | 2004-10-21 |
DE10318026B4 (en) | 2010-05-27 |
DE10318026A1 (en) | 2004-11-04 |
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Owner name: LEICA BIOSYSTEMS NUSSLOCH GMBH, 69226 NUSSLOCH, DE |
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8110 | Request for examination paragraph 44 | ||
8363 | Opposition against the patent | ||
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R008 | Case pending at federal patent court | ||
R010 | Appeal proceedings settled by withdrawal of appeal(s) or in some other way | ||
R034 | Decision of examining division/federal patent court maintaining patent in limited form now final | ||
R206 | Amended patent specification | ||
R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |