DE1035855B - Skin and hair care products - Google Patents

Skin and hair care products

Info

Publication number
DE1035855B
DE1035855B DESCH22388A DESC022388A DE1035855B DE 1035855 B DE1035855 B DE 1035855B DE SCH22388 A DESCH22388 A DE SCH22388A DE SC022388 A DESC022388 A DE SC022388A DE 1035855 B DE1035855 B DE 1035855B
Authority
DE
Germany
Prior art keywords
skin
care products
hair care
hair
acid esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DESCH22388A
Other languages
German (de)
Inventor
Dipl-Chem Dr Gerhard Orlick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hans Schwarzkopf and Henkel GmbH
Original Assignee
Hans Schwarzkopf and Henkel GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hans Schwarzkopf and Henkel GmbH filed Critical Hans Schwarzkopf and Henkel GmbH
Priority to DESCH22388A priority Critical patent/DE1035855B/en
Publication of DE1035855B publication Critical patent/DE1035855B/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair

Description

Haut- und Haarpflegemittel Die Verwendung von Aminosäuren, Keratinhydrolysaten und Proteinen anderer Herkunft zur Bereitung von kosmetischen Präparaten ist seit längerer Zeit bekannt. Ihre günstige Wirkung auf die Haut- und Haarbeschaffenheit ist bei äußerlicher Anwendung sehr gering, da sich die erwähnten Verbindungen zum Teil in Wasser und anderen Lösungsmitteln nur schlecht und in den in der Kosmetik gebräuchlichen Lipoiden fast gar nicht lösen. Dies trifft auch zu für acylierte Aminosäuren wie N-Acetyl-d,l-methionin, das in Kombination mit einem östrogenen Hormon zur Verhütung von Haarausfall eingesetzt worden ist.Skin and hair care products The use of amino acids, keratin hydrolysates and proteins of other origins for the preparation of cosmetic preparations has been since known for a long time. Their beneficial effect on the condition of the skin and hair is very low when used externally, since the mentioned connections to the Part in water and other solvents only poorly and in cosmetics common lipoids almost not dissolve at all. This also applies to acylated ones Amino acids such as N-acetyl-d, l-methionine, which in combination with an estrogenic Hormone has been used to prevent hair loss.

Es wurde nun gefunden, daß man wesentlich bessere Ergebnisse erzielt, wenn man solche Derivate von Aminosäuren verwendet, die eine bessere Löslichkeit in den in der Kosmetik gebräuchlichen Rohstoffen, z. B. Fette, Öle, Wachse, Kohlenwasserstoffe und Alkohole, besitzen. It has now been found that much better results are obtained if one uses such derivatives of amino acids, which have a better solubility in the raw materials commonly used in cosmetics, e.g. B. fats, oils, waxes, hydrocarbons and alcohols.

Es sind dies Derivate von Aminosäuren, die durch Acylierung der Aminogruppe und Veresterung der Carboxylgruppe entstehen.These are derivatives of amino acids that result from acylation of the amino group and esterification of the carboxyl group arise.

Grundsätzlich sind die N-Acylaminosäureester von allen Aminosäuren zur Pflege der Haut und Haare geeignet. Auf Grund ihres physiologischen Charakters werden jedoch die Aminosäuren vorgezogen, welche Bestandteile der natürlichen Proteine sind. Es können sowohl die optisch aktiven N-Acylaminosäureester als auch deren Racemate verwendet werden. Die N-Acylaminosäureester sind an ihrem N-Atom noch zur Salzbildung fähig, und es können auch die entsprechenden anorganischen oder organischen Salze in dem Haut- und Haarpflegemittel zur Anwendung kommen. Zur Acylierung der Aminogruppe oder -gruppen werden ein- oder mehlbasische Carbonsäuren verwendet. Die Veresterung der Carboxylgruppe oder -gruppen erfolgt mit ein- oder mehrwertigen Alkoholen. Basically, the N-acyl amino acid esters are of all amino acids suitable for the care of the skin and hair. Because of their physiological character however, the amino acids are preferred, which are components of natural proteins are. Both the optically active N-acylamino acid esters and their Racemates can be used. The N-acylamino acid esters are still at their N atom Capable of salt formation, and it can also be the corresponding inorganic or organic Salts in which skin and hair care products are used. For acylation of Amino group or groups are mono- or flour-basic carboxylic acids. The carboxyl group or groups are esterified with mono- or polyvalent ones Alcohols.

Die beschriebenen N-Acylaminosäureester lassen sich in Form von Lösungen in geeigneten organischen Lösungsmitteln oder in Wasser verwenden; es kommen aber auch Lösungsmittelgemische in Betracht. Die geeigneten organischen Lösungsmittel können auch mit Wasser verdünnt sein. Die beschriebenen N-Acylaminosäureester können aber auch geeigneten Ölen, Fetten oder Emulsionen zugesetzt werden oder auch als Zusätze zu pulverförmigen Stoffen dienen. Die beschriebenen Haut- und Haarpflegemittel können darüber hinaus Wirkstoffe zur Kräftigung der Haut, des Haarbodens und des Haarwuchses enthalten, wie z. B. Vitamine, Hormone, Antiseptika, Pflanzenauszüge Auf Grund ihrer günstigen Löslichkeitseigenschaften lassen sich die beschriebenen N-Acylaminosäureester besser in Haut- und Haarpflegemittel einarbeiten. Die beschriebenen Hautpflegemittel verbessern das Aussehen der Haut und machen sie geschmeidig. Die beschriebenen Haarpflegemittel kräftigen die Struktur der Haare. The N-acylamino acid esters described can be in the form of solutions use in suitable organic solvents or in water; but there are solvent mixtures are also possible. The appropriate organic solvents can also be diluted with water. The N-acylamino acid esters described can but also suitable oils, fats or emulsions can be added or also as Additives to powdery substances are used. The skin and hair care products described can also use active ingredients to strengthen the skin, scalp and hair Contain hair growth, such as B. Vitamins, hormones, antiseptics, plant extracts Due to their favorable solubility properties, the described Incorporate N-acylamino acid esters better into skin and hair care products. The described Skin care products improve the appearance of the skin and make it supple. the Hair care products described strengthen the structure of the hair.

Beispiele 1. Hautcreme 10,00/, Bienenwachs 50,0 01o Paraffinöl 3,0°/0 Lanolin y A 1,0°/o Sorbitansesquioleat 3,0 0/, N-Acetyl-glycin-benzylester 33,0 O/o Wasser q. s. Parfüm, Konservierungsmittel, Farbstoff 100,0 O/o Die Ölphase A und die Wasserphase werden jede für sich auf etwa 700 C erwärmt. Nachdem sich in der Ö1-phase A alles klar gelöst hat, wird das Wasser unter Rühren langsam zu A gegeben. Unter weiterem Rühren wird abgekühlt.Examples 1. Skin cream 10.00 /, beeswax 50.0 01o paraffin oil 3.0% / 0 lanolin y A 1.0% sorbitan sesquioleate 3.0 0 /, N-acetyl-glycine-benzyl ester 33.0 O / o water qs perfume, preservative, colorant 100.0 O / o The oil phase A and the water phase are each heated separately to about 700 ° C. After everything has clearly dissolved in the oil phase A, the water is slowly added to A while stirring. The mixture is cooled with further stirring.

2. Haarwasser 0,50 0/o d,l-N-Acetyl-methionin-äthylester 0,25 °/0 l-N-Acetyl-glutaminsäure-diäthylesterhydrochlorid 0,25 0/, Natriumpantothenat 52,00 0/o Äthylalkohol (9600ig) 47,00 01o Wasser s. q. Parfüm, Farbstoff 100,00 01o 3. Haarwasser 0,100/, l-N-Benzoyl-histidin-monoglycerinester 0,10 0/, l-N-Acetyl-methionin-äthylester 0,1001, Pilocarpin-hydrochlorid 0,10 01ü Resorcinmonoacetat 1,00 01o Chinarindenextrakt 40,00 0!o Isopropylalkohol 58,60°/o Wasser q. s. Parfüm, Farbstoff 100,00 0/, 4. Haaröl 50,0% Olivenöl 40,0°/0 Paraffinöl 9,001, Isopropylmyristat 0,5 01, d,1-N-Salicylyl-methionin-isopropylester 0,5% I-N-Acetyl-cystein-isopropylester q. s. Parfüm, Konservierungsmittel, Farbstoff lOOp °/o pTENTANSPRbCHE 1. Haut- und Haarpflegemittel, gekennzeichnet durch einen Gehalt an einem oder mehreren N-Acylaminosäureestern in optisch aktiver Form und bzw. oder als Racemat. 2. Hair lotion 0.50% d, 1-N-acetyl-methionine-ethyl ester 0.25% 1-N-acetylglutamic acid diethyl ester hydrochloride 0.25%, sodium pantothenate 52.00 0 / o ethyl alcohol (9600ig) 47.00 01o water see q. Perfume, dye 100.00 01o 3. Hair lotion 0.100 /, l-N-Benzoyl-histidine-monoglycerol ester 0.10 0 /, l-N-acetyl-methionine-ethyl ester 0.1001, pilocarpine hydrochloride 0.10 01u resorcinol monoacetate 1.00 01o quinine bark extract 40.00% isopropyl alcohol 58.60% water q. see perfume, dye 100.00 0 /, 4th Hair oil 50.0% olive oil 40.0% paraffin oil 9.001, isopropyl myristate 0.5 01, d, 1-N-salicylyl methionine isopropyl ester 0.5% I-N-acetyl-cysteine-isopropyl ester q. See perfume, preservative, dye lOOp% / o pTENT CLAIMS 1. Skin and hair care products, characterized by a Content of one or more N-acylamino acid esters in optically active form and or or as a racemate.

Claims (1)

2. Haut- und Haarpflegemittel gemäß Anspruch 1, dadurch gekennzeichnet, daß es die anorganischen oder organischen Salze der N-Acylaminosäureester enthält. 2. skin and hair care products according to claim 1, characterized in that that it contains the inorganic or organic salts of the N-acylamino acid esters. 3. Haut- und Haarpflegemittel gemäß Anspruch 1 oder 2, dadurch gekennzeichnet, daß es einen oder mehrere Zusätze von bekannten Haut- und Haarpflegemitteln wie Vitamine, Hormone, antiseptische Stoffe und Pflanzenauszüge enthält. 3. skin and hair care products according to claim 1 or 2, characterized in that that there are one or more additives of known skin and hair care products such as Contains vitamins, hormones, antiseptics and plant extracts. In Betracht gezogene Druckschriften: »Der Chemiemarkt«, Nr. 7 (Aprilheft 1956), S. 1, einer Beilage zur Zeitschrift »Die Chemische Industriei, Aprilheft 1956. Publications considered: "Der Chemiemarkt", No. 7 (April issue 1956), p. 1, a supplement to the journal »Die Chemische Industriei, April issue 1956.
DESCH22388A 1957-06-29 1957-06-29 Skin and hair care products Pending DE1035855B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DESCH22388A DE1035855B (en) 1957-06-29 1957-06-29 Skin and hair care products

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DESCH22388A DE1035855B (en) 1957-06-29 1957-06-29 Skin and hair care products

Publications (1)

Publication Number Publication Date
DE1035855B true DE1035855B (en) 1958-08-07

Family

ID=7429303

Family Applications (1)

Application Number Title Priority Date Filing Date
DESCH22388A Pending DE1035855B (en) 1957-06-29 1957-06-29 Skin and hair care products

Country Status (1)

Country Link
DE (1) DE1035855B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3235457A (en) * 1962-12-07 1966-02-15 Gillette Co Humectant
US3242052A (en) * 1963-08-13 1966-03-22 Mead Johnson & Co Hair treatment with nu-acylcysteines
EP0572167A1 (en) * 1992-05-20 1993-12-01 Unilever Plc Cosmestic composition
WO2001095866A1 (en) * 2000-06-13 2001-12-20 Unilever Plc Hair oils
JPWO2010058730A1 (en) * 2008-11-19 2012-04-19 ポーラ化成工業株式会社 Wrinkle improving agent
IT202000007234A1 (en) * 2020-04-06 2021-10-06 Isagro Spa Compounds with fungicidal activity, relative agronomic compositions and use for the control of phytopathogenic fungi

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3235457A (en) * 1962-12-07 1966-02-15 Gillette Co Humectant
US3242052A (en) * 1963-08-13 1966-03-22 Mead Johnson & Co Hair treatment with nu-acylcysteines
EP0572167A1 (en) * 1992-05-20 1993-12-01 Unilever Plc Cosmestic composition
WO2001095866A1 (en) * 2000-06-13 2001-12-20 Unilever Plc Hair oils
JPWO2010058730A1 (en) * 2008-11-19 2012-04-19 ポーラ化成工業株式会社 Wrinkle improving agent
US8835498B2 (en) 2008-11-19 2014-09-16 Pola Chemical Industries Inc. Anti-wrinkle agents
JP5746864B2 (en) * 2008-11-19 2015-07-08 ポーラ化成工業株式会社 Wrinkle improving agent
IT202000007234A1 (en) * 2020-04-06 2021-10-06 Isagro Spa Compounds with fungicidal activity, relative agronomic compositions and use for the control of phytopathogenic fungi

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