DE191613T1 - Verfahren zur isolierung von kleinen inseln. - Google Patents

Verfahren zur isolierung von kleinen inseln.

Info

Publication number
DE191613T1
DE191613T1 DE198686300858T DE86300858T DE191613T1 DE 191613 T1 DE191613 T1 DE 191613T1 DE 198686300858 T DE198686300858 T DE 198686300858T DE 86300858 T DE86300858 T DE 86300858T DE 191613 T1 DE191613 T1 DE 191613T1
Authority
DE
Germany
Prior art keywords
small islands
isolating small
isolating
islands
small
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198686300858T
Other languages
English (en)
Inventor
David W. St. Louis Missouri 63131 Us Scharp
Paul E. Webster Groves Missouri 63119 Us Lacy
Edward H. Jennings Missouri 63136 Us Finke
Thomas J. Leslie Missouri 63056 Us Poteat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McDonnell Douglas Corp
Washington University in St Louis WUSTL
Original Assignee
McDonnell Douglas Corp
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McDonnell Douglas Corp, Washington University in St Louis WUSTL filed Critical McDonnell Douglas Corp
Publication of DE191613T1 publication Critical patent/DE191613T1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
DE198686300858T 1985-02-07 1986-02-07 Verfahren zur isolierung von kleinen inseln. Pending DE191613T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69934385A 1985-02-07 1985-02-07
US06/773,459 US4868121A (en) 1985-02-07 1985-09-09 Islet isolation process

Publications (1)

Publication Number Publication Date
DE191613T1 true DE191613T1 (de) 1987-05-21

Family

ID=27106396

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3650662T Expired - Lifetime DE3650662D1 (de) 1985-02-07 1986-02-07 Verfahren zur Isolierung von kleinen Inseln
DE198686300858T Pending DE191613T1 (de) 1985-02-07 1986-02-07 Verfahren zur isolierung von kleinen inseln.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3650662T Expired - Lifetime DE3650662D1 (de) 1985-02-07 1986-02-07 Verfahren zur Isolierung von kleinen Inseln

Country Status (3)

Country Link
US (2) US4868121A (de)
EP (1) EP0191613B1 (de)
DE (2) DE3650662D1 (de)

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US5759830A (en) * 1986-11-20 1998-06-02 Massachusetts Institute Of Technology Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
EP0287896A1 (de) * 1987-04-21 1988-10-26 Walter Huber Verfahren und Einrichtung zur Gewinnung endokriner Inseln aus einem Spenderorgan sowie Verwendung der Inseln zur Behandlung von Stoffwechselkrankheiten
US5079160A (en) * 1987-06-08 1992-01-07 Lacy Paul E Method to isolate clusters of cell subtypes from organs
US5739033A (en) * 1989-09-20 1998-04-14 Vivorx, Inc. Physiological cell separation and method of separating cells using same
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
DK0585368T3 (da) * 1991-04-25 1998-03-16 Univ Brown Res Found Implanterbart biokompatibelt immunisolatorisk vehikel til afgivelse af udvalgte terapeutiske produkter
AU2900792A (en) * 1991-10-24 1993-05-21 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
US5334315A (en) * 1992-01-17 1994-08-02 Pall Corporation Priming system
US5834005A (en) * 1992-02-24 1998-11-10 Encelle, Inc. Bioartificial devices and cellular matrices therefor
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US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US5824331A (en) * 1992-02-24 1998-10-20 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US5273904A (en) * 1992-03-18 1993-12-28 Cobe Laboratories, Inc. Apparatus for purifying islets of Langerhans
JPH08500033A (ja) * 1992-07-29 1996-01-09 ワシントン・ユニバーシティ 生細胞移植のためのポーチの使用
DE4227066A1 (de) * 1992-08-16 1994-02-17 Bernhard Josef Dr Med Hering Langerhans'sche Inseln in reiner Form
FR2696754B1 (fr) * 1992-10-14 1994-11-18 Hospal Ind Méthode d'isolement de cellules à partir d'un organe et dispositif pour sa mise en Óoeuvre.
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
ES2178654T3 (es) * 1993-08-12 2003-01-01 Neurotech Sa Capsulas biocompatibles inmonoaisladoras que contienen celulas geneticamente alteradas para el suministro de moleculas biologicamente activas.
US5908623A (en) * 1993-08-12 1999-06-01 Cytotherapeutics, Inc. Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5550050A (en) 1994-04-15 1996-08-27 Cytotherapeutics, Inc. Method for implanting encapsulated cells in a host
CA2189646C (en) * 1994-06-24 1999-05-25 Francis E. Dwulet A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum
US5629194A (en) * 1994-10-21 1997-05-13 Diacrin, Inc. Isolated porcine pancreatic cells for use in treatment of diseases characterized by insufficient insulin activity
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5679565A (en) * 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets
US6123727A (en) 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5879939A (en) * 1995-05-17 1999-03-09 Neocrin Company Isolation of cells from organ tissue using sonication
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US5702444A (en) * 1995-09-11 1997-12-30 Struthers, Mehta And Maxwell Implantable artificial endocrine pancreas
US5670358A (en) * 1995-10-19 1997-09-23 Baxter International Inc. Method for inhibiting chymopapain and papain enzyme activity with polysaccharides of animal origin
WO1997014788A1 (en) * 1995-10-19 1997-04-24 Baxter International Inc. Method for inhibiting chymopapain and papain enzyme activity with zinc ions
US5989888A (en) * 1996-01-24 1999-11-23 Roche Diagnostics Corporation Purified mixture of collagenase I, collagenase II and two other proteases
US5837444A (en) * 1996-07-16 1998-11-17 Shah; Kumarpal A. Islet cell transplantation machine for diabetes cure
US5830741A (en) * 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
US5922339A (en) * 1998-01-27 1999-07-13 Usala; Anton-Lewis Compositions and methods for biocompatible implants
JP2000007593A (ja) * 1998-06-24 2000-01-11 Asahi Glass Co Ltd ペルフルオロ（ｎ−ペンタン）の製造方法
US6365385B1 (en) 1999-03-22 2002-04-02 Duke University Methods of culturing and encapsulating pancreatic islet cells
US6303355B1 (en) 1999-03-22 2001-10-16 Duke University Method of culturing, cryopreserving and encapsulating pancreatic islet cells
AU6378900A (en) * 1999-07-26 2001-02-13 Uab Research Foundation Protecting pancreatic beta-cells during islet isolation; assessing islet viability and candidate diabetes drugs after islet isolation
EP1289537B1 (de) * 2000-05-31 2005-11-30 Encelle, Inc. Verfahren zur behandlung von chronischen geschwüren
US20020086431A1 (en) * 2000-08-21 2002-07-04 Markham Walter Bruce Sample preparation and slide plating apparatus and method
US7045349B2 (en) * 2001-01-23 2006-05-16 Benedict Daniel J Method of islet isolation using process control
US20040248077A1 (en) * 2002-11-27 2004-12-09 Horacio L. Rodriguez Rilo Cell separation apparatus
US20040161845A1 (en) * 2003-02-14 2004-08-19 Poo Ramon E. Heating apparatus
US20050164522A1 (en) * 2003-03-24 2005-07-28 Kunz Roderick R. Optical fluids, and systems and methods of making and using the same
NZ597965A (en) * 2003-10-08 2013-09-27 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
DE102004011400A1 (de) * 2004-03-05 2005-09-22 Cavis Microcaps Gmbh Technischer Prozess sowie Anlage zur Gewinnung und/oder Verkapselung von lebenden Zellen aus Organen
US7504201B2 (en) * 2004-04-05 2009-03-17 Organ Recovery Systems Method for perfusing an organ and for isolating cells from the organ
WO2006118564A2 (en) * 2004-04-29 2006-11-09 Washington State University Research Foundation MODIFIED CELLS EXPRESSING A PROTEIN THAT MODULATES ACTIVITY OF bHLH PROTEINS, AND USES THEREOF
DE102006026179A1 (de) * 2006-05-29 2007-12-06 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zur in vitro Präparation von lebenden Zellen und/oder Zellansammlungen aus einem Gewebe
US20100159564A1 (en) * 2007-11-30 2010-06-24 Dwulet Francis E Protease resistant recombinant bacterial collagenases
WO2012112982A2 (en) 2011-02-18 2012-08-23 Massachusetts Institute Of Technology Hydrogel encapsulated cells and anti-inflammatory drugs
WO2012158910A2 (en) 2011-05-18 2012-11-22 The Regents Of The University Of California Compositions and methods for treating retinal diseases
US20150132849A1 (en) * 2011-09-28 2015-05-14 Islet Sciences, Inc. Ex vivo maturation of islet cells
US9555007B2 (en) 2013-03-14 2017-01-31 Massachusetts Institute Of Technology Multi-layer hydrogel capsules for encapsulation of cells and cell aggregates
US10172791B2 (en) 2013-03-14 2019-01-08 Massachusetts Institute Of Technology Multi-layer hydrogel capsules for encapsulation of cells and cell aggregates
JP6723169B2 (ja) 2014-08-01 2020-07-15 マサチューセッツ インスティテュート オブ テクノロジー 抗線維化材料のための修飾されたアルギネートおよび用途
EP3297693A1 (de) 2015-05-17 2018-03-28 Massachusetts Institute of Technology Mehrschichtige hydrokapseln zur verkapselung von zellen und zellverbänden
RU2018120104A (ru) 2015-11-01 2019-12-02 Массачусетс Инститьют Оф Текнолоджи Модифицированные альгинаты в качестве противофиброзных материалов и их применения
EP3167911A1 (de) 2015-11-10 2017-05-17 Oniris In si-hpmc-eingekapselte insulinerzeugende zellen zur behandlung von typ-1-diabetes
WO2017218520A1 (en) 2016-06-13 2017-12-21 Massachusetts Institute Of Technology Surface-coated continuous glucose monitors
CN110381956B (zh) 2017-01-27 2024-02-02 康奈尔大学 两性离子修饰的聚合物和水凝胶
WO2018226640A1 (en) 2017-06-05 2018-12-13 The Regents Of The University Of The University Of California Compositions for treating retinal diseases and methods for making and using them
KR20210138606A (ko) 2019-02-15 2021-11-19 윌리엄 마쉬 라이스 유니버시티 이식된 진단 및 치료제를 위한 혈관 형성 장치 및 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868121A (en) * 1985-02-07 1989-09-19 Mcdonnell Douglas Corporation Islet isolation process

Also Published As

Publication number Publication date
EP0191613A2 (de) 1986-08-20
DE3650662D1 (de) 1998-02-05
US5322790A (en) 1994-06-21
EP0191613B1 (de) 1997-12-29
EP0191613A3 (de) 1989-03-08
US4868121A (en) 1989-09-19

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