DE19642234C1 - Implantable medical infusion pump - Google Patents

Implantable medical infusion pump

Info

Publication number
DE19642234C1
DE19642234C1 DE1996142234 DE19642234A DE19642234C1 DE 19642234 C1 DE19642234 C1 DE 19642234C1 DE 1996142234 DE1996142234 DE 1996142234 DE 19642234 A DE19642234 A DE 19642234A DE 19642234 C1 DE19642234 C1 DE 19642234C1
Authority
DE
Germany
Prior art keywords
infusion pump
valves
connection
catheter
throttle sections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1996142234
Other languages
German (de)
Inventor
Karl-Heinz Otto
Jan G Toennies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Codman Neuro Sciences SARL
Original Assignee
Tricumed Medizintechnik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tricumed Medizintechnik GmbH filed Critical Tricumed Medizintechnik GmbH
Priority to DE1996142234 priority Critical patent/DE19642234C1/en
Application granted granted Critical
Publication of DE19642234C1 publication Critical patent/DE19642234C1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate

Abstract

The infusion pump has a drive medium space and a medicament space, a connection (10) for a catheter and a number of throttle points (12,14,16,18) coupled to the latter connection on one side and to the medicament space on the other side. Respective valves (20,22,24,26) which can be operated from the outside are inserted between the catheter connection and each of the throttle points, with a pressure measuring device (28,30,32,34) coupled to the line between each of the valves and the corresponding throttle point.

Description

Die Erfindung betrifft eine implantierbare Infusions­ pumpe mit den Merkmalen des Oberbegriffs des Anspruchs 1, die Patienten implantiert wird, die einen ständigen Bedarf an Zufuhr eines Arzneimittels haben, beispiels­ weise Schmerzpatienten und Spastikern.The invention relates to an implantable infusion pump with the features of the preamble of the claim 1, the patient is implanted, a permanent Have a need for a drug delivery, for example wise pain patients and spastic patients.

Bei der aus der DE 195 15 722 C1 bekannten Infusions­ pumpe sind die Mehrzahl von Drosselstrecken als in ei­ nen Chip eingeätzte Vertiefungen ausgebildet, die Wahl der "aktiven" Drosselstrecke erfolgt durch die Wahl ei­ ner Einbaulage des Chips, bei der die gewünschte Dros­ selstrecke konnektiert ist. Eine nachträgliche Verände­ rung der Durchflußrate ist nicht möglich. In the infusion known from DE 195 15 722 C1 pumps are the more throttle sections than in egg formed a chip etched recesses, the choice the "active" throttle section is made by choosing egg ner installation position of the chip, in which the desired Dros is connected. A subsequent change Flow rate is not possible.  

Aus der DE-OS 28 55 713 ist eine Vorrichtung bekannt, bei der mehrere Infusionsflaschen über stellbare Venti­ le von außen zusammengeschaltet werden können. Die US 5 318 515 zeigt eine außenliegende Infusionspumpe, bei der mehrere parallele Wege über Ventile einzeln geöff­ net werden können.From DE-OS 28 55 713 a device is known with multiple infusion bottles via adjustable venti le can be interconnected from the outside. U.S. 5,318,515 shows an external infusion pump, at which opens several parallel paths individually via valves can be net.

Der Erfindung liegt die Aufgabe zugrunde, eine implan­ tierbare Infusionspumpe zu schaffen, bei der die nach der Implantation von außen geänderte Durchflußrate von außen sensiert werden kann.The invention has for its object an implan to create a viable infusion pump, in which the after the external rate of implantation changed from can be sensed outside.

Erfindungsgemäß wird diese Aufgabe durch die Merkmale des Anspruchs 1 gelöst. Die Unteransprüche geben vor­ teilhafte Weiterbildungen dieser Infusionspumpe an.According to the invention, this object is achieved by the features of claim 1 solved. The sub-claims specify partial further training of this infusion pump.

Die Erfindung wird im folgenden anhand einer Zeichnung erläutert. Dabei zeigt die einzige Figur eine schemati­ sche Darstellung der Drosselstrecken, der Ventile und der zwischen den Ventilen vorgeschalteten Druckmeßein­ richtungen.The invention is described below with reference to a drawing explained. The only figure shows a schematic cal representation of the throttle sections, valves and the upstream pressure measurement between the valves directions.

Die - als Ganzes nicht dargestellte - Infusionspumpe weist ein Gehäuse auf, das einen Balg aufnimmt, in den ein einen Dampfdruck erzeugendes Treibmittel eingefüllt ist. Der verbleibende Raum nimmt das dem Patienten zu verabreichende Arzneimittel auf.The infusion pump, not shown as a whole has a housing that receives a bellows in the a blowing agent generating a steam pressure is filled is. The remaining space increases this for the patient administering drugs.

Ein in der einzigen Figur schematisch dargestellter Chip ist mit vier durch Einätzen von Fluidbahnen gebil­ dete Drosselstrecken 12, 14, 16, 18 unterschiedlicher Länge versehen, deren Eingänge mit dem Arzneimittelraum verbunden sind, so daß an den Eingängen der Drossel­ strecken 12, 14, 16, 18 das zu verabreichende Arznei­ mittel mit einem durch den Dampfdruck des Treibmittels bestimmten Druck anliegt. Hinter den Ausgängen der Drosselstrecken 12, 14, 16, 18 liegen Druckmeßeinrich­ tungen 28, 30, 32, 34, die den Druck an dem jeweiligen Ausgang der Drosselstrecken 12, 14, 16, 18 sensieren und über - nicht den Gegenstand dieser Erfindung bil­ dende - Mittel von außen abfragbar sind.A schematically illustrated in the single figure chip is provided with four gebil finished by etching of fluid paths throttle sections 12, 14, 16, 18 of different lengths, whose inputs are connected with the drug chamber, so that stretch at the inputs of the throttle 12, 14, 16 , 18 the drug to be administered is present at a pressure determined by the vapor pressure of the propellant. Behind the outputs of the throttle sections 12 , 14 , 16 , 18 are Druckmeßeinrich lines 28 , 30 , 32 , 34 , which sense the pressure at the respective outlet of the throttle sections 12 , 14 , 16 , 18 and - not the subject of this invention - Funds can be queried from outside.

In Strömungsrichtung hinter den Druckmesseinrichtungen 28, 30, 32, 34 liegen Ventile 20, 22, 24, 26, die von außen über - nicht den Gegenstand dieser Erfindung bil­ dende - Mittel schaltbar sind.In the flow direction behind the pressure measuring devices 28 , 30 , 32 , 34 are valves 20 , 22 , 24 , 26 , which can be switched from the outside via means not forming the subject matter of this invention.

Ein weiteres Ventil 36 ist zwischen der Zusammenführung der Ausgänge der Ventile 20, 22, 24, 26 und dem Kathe­ teranschluß angeordnet, dem eine weitere Druckmeßein­ richtung 38 vorgeschaltet ist.Another valve 36 is arranged between the merging of the outputs of the valves 20 , 22 , 24 , 26 and the Kathe teranschluß, which is a further Druckmeßein direction 38 upstream.

Die parallele Schaltung der Drosselstrecken 12, 14, 16, 18 zwischen dem Arzneimittelraum und dem Katheteran­ schluß 10 und die Vorsehung der Ventile 20, 22, 24, 26 erlaubt eine nachträgliche Veränderung der Durchfluß­ rate durch ein entsprechendes Schalten der Ventile.The parallel connection of the throttle sections 12 , 14 , 16 , 18 between the drug room and the catheter circuit 10 and the provision of the valves 20 , 22 , 24 , 26 allows a subsequent change in the flow rate by a corresponding switching of the valves.

Wegen der hohen Sicherheitsanforderungen ist es notwen­ dig, daß die Ist-Stellung der Ventile sensiert und von außen abgefragt werden kann. Diese Aufgabe wird durch die Vorsehung der Druckmeßeinrichtungen 28, 30, 32, 34 erfüllt: in dem geöffneten Zustand des einer Druckmeß­ einrichtung nachgeschalteten Ventils entspricht der an­ liegende Druck dem in dem Katheteranschluß (also im we­ sentlichen athmosphärischem Druck), da der Druck in der zugehörigen Drosselstrecke abfällt, in dem geschlosse­ nen Zustand dagegen im wesentlichen dem Treibmittel­ druck, da bei fehlender Strömung kein Druckabfall stattfindet (liegt also in der Größenordnung von 2 bar). Entsprechend mißt die dem weiteren, als Sicher­ heitsventil dienenden Ventil 36 vorgeschaltete Druck­ meßeinrichtung 38 in der geöffneten Stellung des Ven­ tils 36 den Druck an dem Katheteranschluß, in der ge­ schlossenen Stellung des Ventils 36 dagegen dann, wenn wenigstens eines der Ventile 20, 22, 24, 26 geöffnet ist, den Treibmitteldruck.Because of the high safety requirements, it is necessary that the actual position of the valves can be sensed and queried from the outside. This object is achieved by the provision of the pressure measuring devices 28 , 30 , 32 , 34 : in the open state of the valve connected downstream of a pressure measuring device, the applied pressure corresponds to that in the catheter connection (i.e. essentially atmospheric pressure), since the pressure in the associated throttle section drops, in the closed state, however, essentially the propellant pressure, since there is no pressure drop in the absence of flow (is in the order of 2 bar). Accordingly, the other, serving as a safety valve 36 upstream pressure measuring device 38 in the open position of the Ven valve 36 measures the pressure at the catheter connection, in the closed position of the valve 36, however, when at least one of the valves 20 , 22 , 24 , 26 is open, the propellant pressure.

Die Vorsehung einer weiteren, den Drosselstrecken 12, 14, 16, 18 vorgeschalteten Druckmeßeinrichtung 27 er­ laubt die Messung des vor den Drosselstrecken anliegen­ den Drucks und damit eine Ermittlung des über den Dros­ selstrecken tatsächlich abfallenden Drucks.The provision of a further, the throttle sections 12 , 14 , 16 , 18 upstream pressure measuring device 27 he allows the measurement of the pressure in front of the throttle sections and thus a determination of the pressure actually dropping across the throttle sections.

Claims (3)

1. Implantierbare Infusionspumpe mit einem ein Treib­ mittel aufnehmenden Treibmittelraum, einem ein Arznei­ mittel aufnehmenden Arzneimittelraum, einem Anschluß (10) für einen Katheter und einer Mehrzahl von auf ih­ rer einen Seite mit dem Arzneimittelraum und auf ihrer anderen Seite mit dem Katheteranschluß (10) verbundenen Drosselstrecken (12, 14, 16, 18), dadurch gekennzeich­ net, daß zwischen den einzelnen Drosselstrecken (12' 14, 16, 18) und dem Katheteranschluß (10) von außen einstellbare Ventile (20, 22, 24, 26) angeordnet sind, deren Ausgänge vor dem Katheteranschluß (10) zusammen­ geführt sind, und daß zwischen den Drosselstrecken (12, 14, 16, 18) und den Ventilen (20, 22, 24, 26) von außen abfragbare Druckmeßeinrichtungen (28, 30, 32, 34) vor­ gesehen sind.1. Implantable infusion pump with a propellant space receiving a propellant, a medicament containing a medicament, a connection ( 10 ) for a catheter and a plurality of on one side with the medication space and on the other side with the catheter connection ( 10 ) connected throttle sections ( 12 , 14 , 16 , 18 ), characterized in that between the individual throttle sections (12 '14, 16, 18) and the catheter connection ( 10 ) from the outside adjustable valves ( 20 , 22 , 24 , 26 ) are arranged are the outputs of which are brought together in front of the catheter connection ( 10 ) and that between the throttle sections ( 12 , 14 , 16 , 18 ) and the valves ( 20 , 22 , 24 , 26 ) pressure measurement devices ( 28 , 30 , 32 , 34 ) are seen before. 2. Implantierbare Infusionspumpe nach Anspruch 1, dadurch gekennzeichnet, daß ein zwischen der Zusammen­ führung der Ausgänge der Ventile (20, 22, 24, 26) und dem Katheteranschluß (10) angeordnetes weiteres Ventil (36) mit einer diesem vorgeschalteten weiteren Druck­ meßeinrichtung (38) vorgesehen ist.2. Implantable infusion pump according to claim 1, characterized in that a between the assembly of the outputs of the valves ( 20 , 22 , 24 , 26 ) and the catheter connection ( 10 ) arranged further valve ( 36 ) with a further upstream pressure measuring device ( 38 ) is provided. 3. Implantierbare Infusionspumpe nach Anspruch 1 oder 2, gekennzeichnet durch eine den Drosselstrecken (12, 14, 16, 18) vorgeschaltete weitere Druckmeßeinrichtung (27).3. The implantable infusion pump as claimed in claim 1 or 2, characterized by a further pressure measuring device ( 27 ) connected upstream of the throttle sections ( 12 , 14 , 16 , 18 ).
DE1996142234 1996-10-12 1996-10-12 Implantable medical infusion pump Expired - Lifetime DE19642234C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE1996142234 DE19642234C1 (en) 1996-10-12 1996-10-12 Implantable medical infusion pump

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1996142234 DE19642234C1 (en) 1996-10-12 1996-10-12 Implantable medical infusion pump

Publications (1)

Publication Number Publication Date
DE19642234C1 true DE19642234C1 (en) 1998-04-30

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DE1996142234 Expired - Lifetime DE19642234C1 (en) 1996-10-12 1996-10-12 Implantable medical infusion pump

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19821349C1 (en) * 1998-05-13 1999-06-24 Tricumed Medizintechnik Gmbh Implantable infusion pump with selectable infusion rate
DE19915201A1 (en) * 1999-04-03 2000-10-05 Tricumed Medizintechnik Gmbh Anti-blockage, self-powered implanted infusion pump dosing medicament, includes flow restriction unit produced monolithically on silicon substrate with series- and parallel valves
FR2792843A1 (en) * 1999-04-30 2000-11-03 Medtronic Inc Control unit for implantable medication pump with pressurized medicament reservoir has valve with two preset flow rates and command module issuing signal to valve to obtain desired dose
FR2806310A1 (en) * 2000-03-16 2001-09-21 Fresenius Vial METHOD FOR ANALYZING PRESSURE VARIATION IN AN INFUSION DEVICE COMPRISING MULTIPLE INFUSION MODULES
WO2005079885A2 (en) * 2004-02-19 2005-09-01 Advanced Neuromodulation Systems, Inc. Reduced size programmable drug pump
WO2009108476A1 (en) * 2008-02-29 2009-09-03 Infusion Systems, Llc Ambulatory infusion devices and methods with blockage detection
DE102009018024A1 (en) 2009-04-18 2010-10-28 Tricumed Medizintechnik Gmbh Implantable infusion pump for use by physician, has propellant area receiving propellant, and valve formed such that it is switched in closed/opened condition if pressure of substance exceeds/falls below counter-pressure around preset value
US8167832B2 (en) 2006-12-09 2012-05-01 The Alfred E. Mann Foundation For Scientific Research Ambulatory infusion devices and methods including occlusion monitoring
DE102015000786A1 (en) * 2015-01-26 2016-07-28 Tricumed Medizintechnik Gmbh Implantable infusion pump
DE102008064296B4 (en) 2008-12-20 2019-05-16 Tricumed Medizintechnik Gmbh Implantable infusion pump with catheter monitoring
US10300195B2 (en) 2016-01-20 2019-05-28 Medallion Therapeutics, Inc. Ambulatory infusion devices and associated methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2855713A1 (en) * 1978-12-22 1980-06-26 Doehn Manfred Priv Doz Dr Med DEVICE FOR INFUSING SOLUTIONS FROM MULTIPLE INFUSION BOTTLES
US5318515A (en) * 1992-08-17 1994-06-07 Wilk Peter J Intravenous flow regulator device and associated method
DE19515722C1 (en) * 1995-05-03 1996-07-25 Tricumed Gmbh Implanted infusion pump for medicament dosing

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2855713A1 (en) * 1978-12-22 1980-06-26 Doehn Manfred Priv Doz Dr Med DEVICE FOR INFUSING SOLUTIONS FROM MULTIPLE INFUSION BOTTLES
US5318515A (en) * 1992-08-17 1994-06-07 Wilk Peter J Intravenous flow regulator device and associated method
DE19515722C1 (en) * 1995-05-03 1996-07-25 Tricumed Gmbh Implanted infusion pump for medicament dosing

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19821349C1 (en) * 1998-05-13 1999-06-24 Tricumed Medizintechnik Gmbh Implantable infusion pump with selectable infusion rate
DE19915201A1 (en) * 1999-04-03 2000-10-05 Tricumed Medizintechnik Gmbh Anti-blockage, self-powered implanted infusion pump dosing medicament, includes flow restriction unit produced monolithically on silicon substrate with series- and parallel valves
DE19915201B4 (en) * 1999-04-03 2016-03-10 Codman Neuro Sciences Sàrl Implantable infusion pump with switchable throttle sections
FR2792843A1 (en) * 1999-04-30 2000-11-03 Medtronic Inc Control unit for implantable medication pump with pressurized medicament reservoir has valve with two preset flow rates and command module issuing signal to valve to obtain desired dose
US6979315B2 (en) 1999-04-30 2005-12-27 Medtronic, Inc. Passive flow control devices for implantable pumps
DE10020495B4 (en) * 1999-04-30 2006-11-16 Medtronic, Inc., Minneapolis Passive flow control devices for implantable pumps
FR2806310A1 (en) * 2000-03-16 2001-09-21 Fresenius Vial METHOD FOR ANALYZING PRESSURE VARIATION IN AN INFUSION DEVICE COMPRISING MULTIPLE INFUSION MODULES
EP1136089A2 (en) * 2000-03-16 2001-09-26 Fresenius Vial SA Method for analysing varying pressure in an infusion device having multiple infusion modules
EP1136089A3 (en) * 2000-03-16 2002-04-17 Fresenius Vial SA Method for analysing varying pressure in an infusion device having multiple infusion modules
US6834242B2 (en) 2000-03-16 2004-12-21 Fresenius Vial Sas Process for analyzing pressure variation in a perfusion apparatus comprising several units
WO2005079885A3 (en) * 2004-02-19 2009-02-19 Advanced Neuromodulation Sys Reduced size programmable drug pump
WO2005079885A2 (en) * 2004-02-19 2005-09-01 Advanced Neuromodulation Systems, Inc. Reduced size programmable drug pump
US8167832B2 (en) 2006-12-09 2012-05-01 The Alfred E. Mann Foundation For Scientific Research Ambulatory infusion devices and methods including occlusion monitoring
US8961453B2 (en) 2006-12-09 2015-02-24 Medallion Therapeutics, Inc. Ambulatory infusion devices and methods
WO2009108476A1 (en) * 2008-02-29 2009-09-03 Infusion Systems, Llc Ambulatory infusion devices and methods with blockage detection
US7867192B2 (en) 2008-02-29 2011-01-11 The Alfred E. Mann Foundation For Scientific Research Ambulatory infusion devices and methods with blockage detection
DE102008064296B4 (en) 2008-12-20 2019-05-16 Tricumed Medizintechnik Gmbh Implantable infusion pump with catheter monitoring
DE102009018024A1 (en) 2009-04-18 2010-10-28 Tricumed Medizintechnik Gmbh Implantable infusion pump for use by physician, has propellant area receiving propellant, and valve formed such that it is switched in closed/opened condition if pressure of substance exceeds/falls below counter-pressure around preset value
DE102015000786A1 (en) * 2015-01-26 2016-07-28 Tricumed Medizintechnik Gmbh Implantable infusion pump
US10300195B2 (en) 2016-01-20 2019-05-28 Medallion Therapeutics, Inc. Ambulatory infusion devices and associated methods

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Owner name: TRICUMED MEDIZINTECHNIK GMBH, 24143 KIEL, DE

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Owner name: CODMAN NEURO SCIENCES SARL, LE LOCLE, CH

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Free format text: PATENT- UND RECHTSANWAELTE BARDEHLE, PAGENBERG, DOST, ALTENBURG, GEISSLER, ISENBRUCK, 81679 MUENCHEN

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