DE2008010A1 - Bone and teeth substitutes - Google Patents

Bone and teeth substitutes

Info

Publication number
DE2008010A1
DE2008010A1 DE19702008010 DE2008010A DE2008010A1 DE 2008010 A1 DE2008010 A1 DE 2008010A1 DE 19702008010 DE19702008010 DE 19702008010 DE 2008010 A DE2008010 A DE 2008010A DE 2008010 A1 DE2008010 A1 DE 2008010A1
Authority
DE
Germany
Prior art keywords
bone
eutectoid
coating
parts
ceramic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19702008010
Other languages
German (de)
Other versions
DE2008010B2 (en
DE2008010C3 (en
Inventor
Antonin Dr 8630 Coburg M Novotny
Original Assignee
Schneider, & Co , 5020 Frechen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schneider, & Co , 5020 Frechen filed Critical Schneider, & Co , 5020 Frechen
Priority to DE19702008010 priority Critical patent/DE2008010C3/en
Publication of DE2008010A1 publication Critical patent/DE2008010A1/en
Publication of DE2008010B2 publication Critical patent/DE2008010B2/de
Application granted granted Critical
Publication of DE2008010C3 publication Critical patent/DE2008010C3/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite

Abstract

Suitably shaped solid material such as a metal, ceramic, or synthetic material, is coated with an eutectoid of tri- nd tetracalcium phosphate (pref. bone ash), and the coating is heated in water vapour at about 1000 degrees C, whereby hydroxylapatite, Ca5(PO4)3OH is formed which is the main mineral component of bones and is completely compatible with tissues of human body. The strong core ensures a sufficient toughness of the product.

Description

Verfahren zur Herstellung von Knochen- und Zahnersatzteilen0 Die Erfindung bezieht sich auf die Herstellung von Transplantaten und richtet sich insbesondere auf die Herstellung von Knochen- oder Zahnersatzteilen. Process for the production of bone and tooth replacement parts0 Die Invention relates and is particularly directed to the manufacture of grafts on the production of bone or tooth replacement parts.

Es ist bekannt, Knochenteile von einem Körperteil in einen anderen Körperteil zu transplantieren. Solche Transplantationen werden schon seit längerer Zeit mit mehr oder weniger guten Erfolg durchgeführt, In Jedem Falle sind abersolchen Xranaplantationen Donor und Akzeptor ein und diesselbe Person.It is known to move bone parts from one part of the body to another Transplant body part. Such transplants have been around for a long time Time carried out with more or less good success, but such are in any case Xranaplantations donor and acceptor one and the same person.

Es ist ferner bekannt, Knochenteile, z. B. Hdftgelenke und andere Gelenke durch entsprechend ausgebildete Teile aus Kunststoff oder aus mit Kunststoff dberzogenen, dem zu ersetzenden Knochenteil entsprechend geformten Metallteilen zu ersetzen.It is also known to use bone parts, e.g. B. Hip joints and others Joints by appropriately designed parts made of plastic or made of plastic Coated metal parts shaped to match the bone part to be replaced to replace.

Obwohl solche Operationen zu recht guten Erfolgen führen, sind ele Jedoch In den seltensten Fällen eine echte und dauerhafte Lösung.Although such operations lead to fairly good results, they are ele However, in the rarest of cases a real and permanent solution.

Es ist ferner bereits in Erwägung gezogen worden, aus Keramik bestehende gnochenersatsteile zu verwenden. Die erste Stufe hierfür war die Verwendung reinen Aluminiumoxyds, von dem man annahm, daß es in seiner Elastizität den menschlichen Knochen im wesentlichen entspreche. Auch die Imprägnation solcher Aluminiumozydmaterialien mit Epoxydharzen ist bereits bekannt.It has also been considered to be made of ceramics to use bone replacement parts. The first stage for doing this was using pure Aluminum oxide, which was assumed to have the same elasticity as human Bones essentially correspond. Also the impregnation of such alumina materials with epoxy resins is already known.

Man hat auch bereits versucht, aus Keramikmaterial bestehende Zähne einpflanzen.Attempts have also been made to make teeth made of ceramic material plant.

Es ist ferner bekannt, dass der Hauptbestandteil des mineralischen Knochenteils durch Hydrgylapatit (Ca5 (PO4) 3 . OH) gebildet wird. Die Herstellung von Knochen- und Zahnersatzteilen aus solchen Calciumphosphaten ist Jedoch nicht erfolgreich, weil diese Ersatzteile niemals die Festigkeitswerte erreichen, die es ermöglichen würden, sie gefahrlos in den menschlichen Körper einzusetzen.It is also known that the main component of the mineral Part of the bone is formed by hydrgylapatite (Ca5 (PO4) 3. OH). The production However, bone and tooth replacement parts made from such calcium phosphates are not successful because these spare parts never achieve the strength values that would allow them to be safely inserted into the human body.

Andererseits zeigt aber gerade Hydroxylapatit Eigenschaften, die ein gutes Anwachsen von Muskel- und Bindegewebe an den Knochenersatzteil aussichtsreich erscheinen lässt.On the other hand, hydroxyapatite shows properties that are a good growth of muscle and connective tissue on the bone replacement part promising makes appear.

Die Erfindung erstrebt also die Schaffung eines Verfahrens zur Herstellung von Knochen- und Zahnersatzteilen, bei denen die wertvollen Eigenschaften des Hydroxylapatits und ähnlicher Calciumphosphatverbindungen zur Wirkung kommen, trotzdem aber ein Ersatzteil entsteht, der auch die nötige Festigkeit aufweist.The invention thus seeks to provide a method of manufacture of bone and dental prosthesis parts, where the valuable properties of hydroxyapatite and similar calcium phosphate compounds come into play, but still a Spare part is created that also has the necessary strength.

Zur optimalen Herstellung des Hydroxylapatits benötigt man eine eutektische Mischung des Tricalciumphosphates und des Tetracalciumphosphates. Diese Mischung kann man sythetisch herstellen oder vorzugsweise als Eutektoid die Knochenasche verwenden.For the optimal production of the hydroxyapatite one needs a eutectic Mixture of tricalcium phosphate and tetracalcium phosphate. This mixture can be produced sythetically or, preferably as a eutectoid, the bone ash use.

Dieses Eutektoid kann man durch einen Heißspritzprozess auf eine mechanisch geeignete Unterlage aufspritzen.This eutectoid can be mechanically applied by a hot spray process Spray on a suitable surface.

Das erfindungegemässe Verfahren wird vorteilhaft so geführt, daß wenigstens der Ueberzug bei einer Temperatur von ca.The process according to the invention is advantageously carried out so that at least the coating at a temperature of approx.

10000C in einer Wasserdampfatmosphäre geglüht wird.10000C is annealed in a steam atmosphere.

lurch die Erfindung werden also die hervorragenden Eigenschaften des Hydroxylapatits zur erstellung von Knochen- und Zahnersatz teilen ausgenutzt.With the invention, the excellent properties of the Hydroxylapatite used to create bone and denture parts.

Ausführungsbeispiel Eine eutektische Mischung aus Tricalciumphosphat und Tetracalciumphosphat wird bei ca. 1.560°C geschmolzen. Exemplary embodiment A eutectic mixture of tricalcium phosphate and tetracalcium phosphate is melted at about 1,560 ° C.

Nach dem Abkühlen der Schmelze bildet sich ein Glas. Dieses Glas wird zermahlen und mit Hilfe einer Flamm- oderPlasmaspritzvorrichtung auf eine metallische oder nicht metallische Unterlage, die im wesentlichen die Form des zu ersetzenden Knochen- oder Zahnteils aufweist, aufgetragen.After the melt has cooled, a glass forms. This glass will grind and with the help of a flame or plasma spray device on a metallic or non-metallic backing, which is essentially the shape of the one to be replaced Has bone or tooth part applied.

Anschliessend wird wenigstens die aus diesem Überzug bestehende Oberfläche bei ca. 100000 in einer wasserdampfhaltigen Atmosphär geglüht und damit in Hydroxylapatit zurückgeführt.Then at least the surface consisting of this coating Annealed at approx. 100,000 in an atmosphere containing water vapor and thus in hydroxyapatite returned.

Anstelle eines eutektischen Gemisches aus Tricalciumphosphat und Tetracalciumphosphat kann auch entsprechend gemahlene Knochenasche Verwendung finden.Instead of a eutectic mixture of tricalcium phosphate and tetracalcium phosphate appropriately ground bone ash can also be used.

-Patentanspruche : - -Patent claims: -

Claims (3)

Pa t e n t a n s p r ü c h e : Verfahren zum Herstellen von Knochen- und Zahnersatzteilen, da d u r c h g e k e n n z e i c h n e t , daß auf einen dem zu ersetzenden Knochen- oder Zahnteil nachgebildeten Kern aus einem ausreichend festen Material, wie Metall, Keramik oder einem Kunststoff, ein Überzug aus einem Eutektoid aus Tricalciumphosphat und Tetracalciumphosphat heiß aufgespritzt wird. Pat e n t a n s p r ü c h e: Method for producing bone and dental prosthesis parts, as it is indicated that on one of the To be replaced bone or tooth part replicated from a core from a sufficiently solid material, such as metal, ceramic or a plastic, a coating of one Eutectoid made of tricalcium phosphate and tetracalcium phosphate is sprayed on hot. 2. Verfahren nach Anspruch 1, d a d u r c h g e k e n n -z e i c h n e t , daß als Eutektoid Knochenasche verwendet wird.2. The method according to claim 1, d a d u r c h g e k e n n -z e i c h n e t that bone ash is used as the eutectoid. 3. Verfahren nach Anspruch 1 und/oder 2, d a d u r c h g e k e n n z e i c h n e t , dass wenigstens der Überzug bei einer Temperatur von ca. 100000 in einer Wasserdampfatmosphäre geglüht wird.3. The method according to claim 1 and / or 2, d a d u r c h g e k e n n notes that at least the coating is at a temperature of about 100,000 is annealed in a steam atmosphere.
DE19702008010 1970-02-20 1970-02-20 Process for the manufacture of dental implants Expired DE2008010C3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19702008010 DE2008010C3 (en) 1970-02-20 1970-02-20 Process for the manufacture of dental implants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702008010 DE2008010C3 (en) 1970-02-20 1970-02-20 Process for the manufacture of dental implants

Publications (3)

Publication Number Publication Date
DE2008010A1 true DE2008010A1 (en) 1971-08-26
DE2008010B2 DE2008010B2 (en) 1979-10-18
DE2008010C3 DE2008010C3 (en) 1980-07-10

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Family Applications (1)

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DE19702008010 Expired DE2008010C3 (en) 1970-02-20 1970-02-20 Process for the manufacture of dental implants

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DE (1) DE2008010C3 (en)

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2628284A1 (en) * 1975-07-01 1977-01-27 Ceraver METAL ROD FOR INSERT IN A BONE SHAFT FOR A PROSTHESIS
DE2620907A1 (en) * 1976-05-12 1977-11-17 Battelle Institut E V ANCHORING FOR HIGHLY LOADED ENDOPROSTHESES
DE2620890A1 (en) * 1976-05-12 1977-11-17 Battelle Institut E V Partially absorbable bone prosthesis compsn. - comprises calcined calcium phosphates and a bioresistant polymer
DE2810129A1 (en) * 1977-03-16 1978-09-28 Ceraver IMPLANTABLE METAL PIN
DE2821354A1 (en) * 1977-05-20 1978-11-23 Kureha Chemical Ind Co Ltd MATERIAL DESIGN FOR IMPLANT PURPOSES
FR2397827A1 (en) * 1977-07-23 1979-02-16 Riess Guido ARTIFICIAL TOOTH WITH IMPLANTABLE ROOT
DE2759214A1 (en) * 1977-12-31 1979-07-05 Scheicher Hans METHOD OF MANUFACTURING IMPLANTS
FR2410995A1 (en) * 1977-12-09 1979-07-06 Riess Guido DENTAL IMPLANT, AND CORRESPONDING MILLING DEVICE
DE2827529A1 (en) * 1978-06-23 1980-01-03 Battelle Institut E V IMPLANTABLE BONE REPLACEMENT MATERIAL BASED ON CALCIUM PHOSPHATE CERAMICS IN A MATRIX MATERIAL
DE2840064A1 (en) * 1978-09-14 1980-03-20 Scheicher Hans Prodn. of hydroxy:apatite contg. material - by calcining tooth or bone, useful for filling bones, insertion of implants etc.
US4223412A (en) * 1976-12-16 1980-09-23 Sumitomo Chemical Company, Limited Implants for bones, joints or tooth roots
EP0023608A1 (en) * 1979-07-11 1981-02-11 Riess, Guido, Dr. med. dent. Bone implant for prostheses and bone fixation parts and process for its manufacture
FR2484246A1 (en) * 1980-06-17 1981-12-18 Europ Propulsion PROCESS FOR PRODUCING BIOACTIVE COATINGS ON BONE PROSTHESES, AND PROSTHESES THUS OBTAINED
FR2548011A2 (en) * 1983-07-01 1985-01-04 Europ Propulsion PROCESS FOR MAKING BIOACTIVE DEPOSITS OF CALCIUM PHOSPHATES AND PRODUCTS OBTAINED
EP0149425A1 (en) * 1984-01-11 1985-07-24 Mathys Co Robert Glenoid cavity made of plastics
FR2569566A1 (en) * 1984-08-31 1986-03-07 Bristol Myers Co IMPLANT AND METHOD OF MANUFACTURING
EP0285826A2 (en) * 1987-04-04 1988-10-12 BK LADENBURG GmbH, Gesellschaft für chemische Erzeugnisse Implant with a bioactive coating
USRE33161E (en) * 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
USRE33221E (en) * 1982-04-29 1990-05-22 American Dental Association Health Foundation Dental restorative cement pastes
DE9001256U1 (en) * 1989-02-06 1990-07-12 Pfizer Hospital Products Group, Inc., New York, N.Y., Us
US5137534A (en) * 1988-01-11 1992-08-11 Asahi Kogaku Kogyo K.K. Method for producing dental and medical bone prosthesis and bone prosthesis produced thereby
US5522893A (en) * 1993-03-12 1996-06-04 American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2620056C2 (en) * 1976-05-06 1984-08-16 Albert Paris Saragossi Process for the manufacture of dentures

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2628284A1 (en) * 1975-07-01 1977-01-27 Ceraver METAL ROD FOR INSERT IN A BONE SHAFT FOR A PROSTHESIS
DE2620907A1 (en) * 1976-05-12 1977-11-17 Battelle Institut E V ANCHORING FOR HIGHLY LOADED ENDOPROSTHESES
DE2620890A1 (en) * 1976-05-12 1977-11-17 Battelle Institut E V Partially absorbable bone prosthesis compsn. - comprises calcined calcium phosphates and a bioresistant polymer
US4223412A (en) * 1976-12-16 1980-09-23 Sumitomo Chemical Company, Limited Implants for bones, joints or tooth roots
DE2810129A1 (en) * 1977-03-16 1978-09-28 Ceraver IMPLANTABLE METAL PIN
DE2821354A1 (en) * 1977-05-20 1978-11-23 Kureha Chemical Ind Co Ltd MATERIAL DESIGN FOR IMPLANT PURPOSES
FR2397827A1 (en) * 1977-07-23 1979-02-16 Riess Guido ARTIFICIAL TOOTH WITH IMPLANTABLE ROOT
FR2410995A1 (en) * 1977-12-09 1979-07-06 Riess Guido DENTAL IMPLANT, AND CORRESPONDING MILLING DEVICE
DE2759214A1 (en) * 1977-12-31 1979-07-05 Scheicher Hans METHOD OF MANUFACTURING IMPLANTS
DE2827529A1 (en) * 1978-06-23 1980-01-03 Battelle Institut E V IMPLANTABLE BONE REPLACEMENT MATERIAL BASED ON CALCIUM PHOSPHATE CERAMICS IN A MATRIX MATERIAL
EP0006544A1 (en) * 1978-06-23 1980-01-09 Battelle-Institut e.V. Implantable material for bone replacement based on calcium phosphate ceramics in a matrix and method of preparing same
DE2840064A1 (en) * 1978-09-14 1980-03-20 Scheicher Hans Prodn. of hydroxy:apatite contg. material - by calcining tooth or bone, useful for filling bones, insertion of implants etc.
EP0023608A1 (en) * 1979-07-11 1981-02-11 Riess, Guido, Dr. med. dent. Bone implant for prostheses and bone fixation parts and process for its manufacture
US4599085A (en) * 1979-07-11 1986-07-08 Neodontics, Inc. Bone implant member for prostheses and bone connecting elements and process for the production thereof
FR2484246A1 (en) * 1980-06-17 1981-12-18 Europ Propulsion PROCESS FOR PRODUCING BIOACTIVE COATINGS ON BONE PROSTHESES, AND PROSTHESES THUS OBTAINED
USRE33221E (en) * 1982-04-29 1990-05-22 American Dental Association Health Foundation Dental restorative cement pastes
USRE33161E (en) * 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
FR2548011A2 (en) * 1983-07-01 1985-01-04 Europ Propulsion PROCESS FOR MAKING BIOACTIVE DEPOSITS OF CALCIUM PHOSPHATES AND PRODUCTS OBTAINED
EP0130916A1 (en) * 1983-07-01 1985-01-09 SOCIETE EUROPEENNE DE PROPULSION (S.E.P.) Société Anonyme dite: Method of producing bioactive calcium phosphate deposits, and products so obtained
EP0149425A1 (en) * 1984-01-11 1985-07-24 Mathys Co Robert Glenoid cavity made of plastics
NL8502127A (en) * 1984-08-31 1986-03-17 Bristol Myers Co IMPLANTED BODY AND METHOD OF MANUFACTURE THEREOF.
FR2569566A1 (en) * 1984-08-31 1986-03-07 Bristol Myers Co IMPLANT AND METHOD OF MANUFACTURING
EP0285826A2 (en) * 1987-04-04 1988-10-12 BK LADENBURG GmbH, Gesellschaft für chemische Erzeugnisse Implant with a bioactive coating
EP0285826A3 (en) * 1987-04-04 1989-09-13 Mtu Muenchen Gmbh Implant with a bioactive coating
US5137534A (en) * 1988-01-11 1992-08-11 Asahi Kogaku Kogyo K.K. Method for producing dental and medical bone prosthesis and bone prosthesis produced thereby
DE9001256U1 (en) * 1989-02-06 1990-07-12 Pfizer Hospital Products Group, Inc., New York, N.Y., Us
US5522893A (en) * 1993-03-12 1996-06-04 American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same
US5542973A (en) * 1993-03-12 1996-08-06 The American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same
US5545254A (en) * 1993-03-12 1996-08-13 The American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same

Also Published As

Publication number Publication date
DE2008010B2 (en) 1979-10-18
DE2008010C3 (en) 1980-07-10

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