DE3067379D1 - Solid preparation comprising cobamamide or mecobalamin and process for preparing same - Google Patents

Solid preparation comprising cobamamide or mecobalamin and process for preparing same

Info

Publication number
DE3067379D1
DE3067379D1 DE8080106850T DE3067379T DE3067379D1 DE 3067379 D1 DE3067379 D1 DE 3067379D1 DE 8080106850 T DE8080106850 T DE 8080106850T DE 3067379 T DE3067379 T DE 3067379T DE 3067379 D1 DE3067379 D1 DE 3067379D1
Authority
DE
Germany
Prior art keywords
cobamamide
mecobalamin
solid preparation
preparing same
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080106850T
Other languages
English (en)
Inventor
Susumu Iwagiri
Teiichi Hattori
Teruyoshi Nasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DE3067379D1 publication Critical patent/DE3067379D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
DE8080106850T 1979-11-22 1980-11-06 Solid preparation comprising cobamamide or mecobalamin and process for preparing same Expired DE3067379D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15074379A JPS5675436A (en) 1979-11-22 1979-11-22 Solid pharmaceutical containing cobamamide or mecobalamin

Publications (1)

Publication Number Publication Date
DE3067379D1 true DE3067379D1 (en) 1984-05-10

Family

ID=15503438

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080106850T Expired DE3067379D1 (en) 1979-11-22 1980-11-06 Solid preparation comprising cobamamide or mecobalamin and process for preparing same

Country Status (6)

Country Link
US (1) US4337246A (de)
EP (1) EP0029534B1 (de)
JP (1) JPS5675436A (de)
DE (1) DE3067379D1 (de)
ES (1) ES8205557A1 (de)
PH (1) PH16747A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT376879B (de) * 1982-10-27 1985-01-10 Gerot Pharmazeutika Verfahren zur herstellung einer injektionsloesung
US5909825A (en) * 1997-04-17 1999-06-08 Lydford; Steven R. Beveridge dispensing system
DE19722445C2 (de) * 1997-05-28 2000-07-13 Veit Gmbh & Co Bundspannvorrichtung
ES2263216T3 (es) * 1997-07-25 2006-12-01 Alpex Pharma S.A. Procedimiento para la preparacion de un granulado adecuado para la preparacion de comprimidos solubles en la boca rapidamente disgregables.
US6797521B2 (en) * 1999-10-26 2004-09-28 University Of Utah Research Foundation Fluorescent cobalamins and uses thereof
US8142799B2 (en) * 2001-12-18 2012-03-27 Tamea Rae Sisco High potency clinical anti-craving treatment and method of use
US8142800B1 (en) 2001-12-18 2012-03-27 Tamea Rae Sisco Oral high potency clinical anti-craving treatment and method of use
JP5365777B2 (ja) * 2006-09-15 2013-12-11 アステラス製薬株式会社 光に対して安定なラモセトロンの固形医薬組成物
JP2012041290A (ja) * 2010-08-18 2012-03-01 Sawai Pharmaceutical Co Ltd ラフチジン含有固形製剤
CN104473882B (zh) * 2014-12-25 2018-10-02 北京华禧联合科技发展有限公司 一种甲钴胺颗粒
CN109248149A (zh) * 2018-11-30 2019-01-22 无锡福祈制药有限公司 一种含有甲钴胺的药物组合物及其制备方法
CN109481420B (zh) * 2018-12-03 2020-11-10 江苏四环生物制药有限公司 一种甲钴胺缓释胶囊
CN109820831A (zh) * 2019-03-26 2019-05-31 江苏四环生物制药有限公司 一种甲钴胺分散片的制粒方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2959520A (en) * 1958-04-07 1960-11-08 Takeda Pharmaceutical Stabilized aqueous solution of vitamin b complex containing cyanocobalamin and thiocyanates
DE1617638A1 (de) * 1967-05-24 1971-05-13 Miles Lab Tablettenbindemittel
BE753787A (en) * 1970-07-23 1970-12-31 Yamanouchi Pharma Co Ltd Stabilized syrups containing coenzyme type - vitamin b12 or methylcobalamine

Also Published As

Publication number Publication date
PH16747A (en) 1984-02-10
JPS5675436A (en) 1981-06-22
EP0029534A2 (de) 1981-06-03
EP0029534B1 (de) 1984-04-04
ES497062A0 (es) 1982-06-16
ES8205557A1 (es) 1982-06-16
EP0029534A3 (en) 1982-04-14
US4337246A (en) 1982-06-29

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee