DE3268533D1 - Inhalation drugs, methods for their production and pharmaceutical formulations containing them - Google Patents

Inhalation drugs, methods for their production and pharmaceutical formulations containing them

Info

Publication number
DE3268533D1
DE3268533D1 DE8282200841T DE3268533T DE3268533D1 DE 3268533 D1 DE3268533 D1 DE 3268533D1 DE 8282200841 T DE8282200841 T DE 8282200841T DE 3268533 T DE3268533 T DE 3268533T DE 3268533 D1 DE3268533 D1 DE 3268533D1
Authority
DE
Germany
Prior art keywords
production
methods
pharmaceutical formulations
formulations containing
inhalation drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282200841T
Other languages
English (en)
Inventor
Raymond Brian Forrester
Terence David Boardman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10523464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3268533(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fisons Ltd filed Critical Fisons Ltd
Application granted granted Critical
Publication of DE3268533D1 publication Critical patent/DE3268533D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
DE8282200841T 1981-07-24 1982-07-06 Inhalation drugs, methods for their production and pharmaceutical formulations containing them Expired DE3268533D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8122846 1981-07-24

Publications (1)

Publication Number Publication Date
DE3268533D1 true DE3268533D1 (en) 1986-02-27

Family

ID=10523464

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282200841T Expired DE3268533D1 (en) 1981-07-24 1982-07-06 Inhalation drugs, methods for their production and pharmaceutical formulations containing them

Country Status (26)

Country Link
US (1) US4590206A (de)
EP (1) EP0072046B1 (de)
JP (1) JPS5859914A (de)
KR (1) KR890002908B1 (de)
AU (1) AU540826B2 (de)
BE (1) BE893912A (de)
CA (1) CA1187415A (de)
CH (1) CH657273A5 (de)
DE (1) DE3268533D1 (de)
DK (1) DK159716C (de)
FI (1) FI822548L (de)
FR (1) FR2510405B1 (de)
GR (1) GR76229B (de)
HK (1) HK10088A (de)
HU (1) HU196904B (de)
IE (1) IE53640B1 (de)
IL (1) IL66375A0 (de)
LU (1) LU84291A1 (de)
MA (1) MA19548A1 (de)
MY (1) MY8700857A (de)
NO (1) NO156394C (de)
NZ (1) NZ201341A (de)
PH (1) PH22759A (de)
PT (1) PT75310B (de)
SG (1) SG68487G (de)
ZA (1) ZA825222B (de)

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US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
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US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
DE69535897D1 (de) 1994-03-07 2009-01-22 Nektar Therapeutics Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin
ES2245780T3 (es) * 1994-05-18 2006-01-16 Nektar Therapeutics Metodos y composiciones para la formulacion de interferones como un polvo seco.
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
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SE9700136D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
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US5612053A (en) 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
JPH10510198A (ja) * 1995-05-12 1998-10-06 ジェネンテク・インコーポレイテッド 機能生物学的物質の粗いスプレー供給
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US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
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SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
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US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
DK1019022T4 (da) * 1997-09-29 2010-11-08 Novartis Ag Perforerede mikropartikler og fremgangsmåde til anvendelse deraf
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6433040B1 (en) * 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
AU2081999A (en) * 1998-01-13 1999-08-02 Astrazeneca Uk Limited Pharmaceutical compostition comprising a compound having dopamine (D2) receptor agonist activity and a compound (B) having Beta2 adrenoreceptor agonist activity
WO1999054376A1 (fr) * 1998-04-20 1999-10-28 Cosmo Research Institute Polyester et procede de production de celui-ci
US6451349B1 (en) * 1998-08-19 2002-09-17 Quadrant Healthcare (Uk) Limited Spray-drying process for the preparation of microparticles
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US6858199B1 (en) * 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
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US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
ES2305057T3 (es) 2000-02-28 2008-11-01 Pharmakodex Limited Dispositivo para la administracion de farmacos orales.
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
WO2001085136A2 (en) 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
WO2002009669A2 (en) * 2000-08-01 2002-02-07 Inhale Therapeutic Systems, Inc. Apparatus and process to produce particles having a narrow size distribution and particles made thereby
SE0002822L (sv) * 2000-08-04 2002-01-29 Microdrug Ag Elektropulver
FI20002216A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
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EP1345629A2 (de) * 2000-12-29 2003-09-24 Advanced Inhalation Research, Inc. Inhalationspartikel mit verzögerter freigabe
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DE10128779A1 (de) † 2001-06-13 2003-01-02 Boehringer Ingelheim Pharma Verfahren zur Reinigung von Hartgelatinekapseln
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Family Cites Families (6)

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US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1569611A (en) * 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520248A (en) * 1975-07-24 1978-08-02 Fisons Ltd Sodium cromoglycate containing medicament
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Also Published As

Publication number Publication date
AU8635582A (en) 1983-02-10
PH22759A (en) 1988-12-12
FR2510405A1 (fr) 1983-02-04
NZ201341A (en) 1985-05-31
PT75310A (en) 1982-08-01
FI822548L (fi) 1983-01-25
CH657273A5 (fr) 1986-08-29
LU84291A1 (fr) 1983-02-07
BE893912A (fr) 1983-01-24
HU196904B (en) 1989-02-28
EP0072046A1 (de) 1983-02-16
CA1187415A (en) 1985-05-21
FR2510405B1 (fr) 1985-07-26
DK159716C (da) 1991-04-29
NO822556L (no) 1983-01-25
FI822548A0 (fi) 1982-07-20
HK10088A (en) 1988-02-12
US4590206A (en) 1986-05-20
MA19548A1 (fr) 1983-04-01
KR840000226A (ko) 1984-02-18
DK325982A (da) 1983-01-25
NO156394B (no) 1987-06-09
KR890002908B1 (ko) 1989-08-11
PT75310B (en) 1985-11-29
IE821770L (en) 1983-01-24
SG68487G (en) 1988-02-19
AU540826B2 (en) 1984-12-06
DK159716B (da) 1990-11-26
NO156394C (no) 1987-09-16
EP0072046B1 (de) 1986-01-15
IE53640B1 (en) 1989-01-04
JPH0468285B2 (de) 1992-11-02
JPS5859914A (ja) 1983-04-09
GR76229B (de) 1984-08-04
MY8700857A (en) 1987-12-31
ZA825222B (en) 1983-05-25
IL66375A0 (en) 1982-11-30

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation