DE3277520D1 - Pharmaceutical multiple-units formulation - Google Patents

Pharmaceutical multiple-units formulation

Info

Publication number
DE3277520D1
DE3277520D1 DE8282306170T DE3277520T DE3277520D1 DE 3277520 D1 DE3277520 D1 DE 3277520D1 DE 8282306170 T DE8282306170 T DE 8282306170T DE 3277520 T DE3277520 T DE 3277520T DE 3277520 D1 DE3277520 D1 DE 3277520D1
Authority
DE
Germany
Prior art keywords
coating
cores
active substance
substance
units
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282306170T
Other languages
English (en)
Inventor
Helle Bechgaard
Peter Houmoeller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BENZON PHARMA A/S, HVIDOVRE, DK
Original Assignee
Alfred Benzon AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfred Benzon AS filed Critical Alfred Benzon AS
Application granted granted Critical
Publication of DE3277520D1 publication Critical patent/DE3277520D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
DE8282306170T 1981-11-20 1982-11-19 Pharmaceutical multiple-units formulation Expired DE3277520D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK516481A DK150008C (da) 1981-11-20 1981-11-20 Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat

Publications (1)

Publication Number Publication Date
DE3277520D1 true DE3277520D1 (en) 1987-12-03

Family

ID=8140030

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8282306170T Expired DE3277520D1 (en) 1981-11-20 1982-11-19 Pharmaceutical multiple-units formulation
DE198282306170T Pending DE80341T1 (de) 1981-11-20 1982-11-19 Pharmazeutische formulierungen mit mehrfachen einheiten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198282306170T Pending DE80341T1 (de) 1981-11-20 1982-11-19 Pharmazeutische formulierungen mit mehrfachen einheiten.

Country Status (12)

Country Link
US (1) US4606909A (de)
EP (1) EP0080341B1 (de)
JP (1) JPS5892610A (de)
AT (1) ATE30380T1 (de)
AU (1) AU563725B2 (de)
CA (1) CA1198370A (de)
DE (2) DE3277520D1 (de)
DK (1) DK150008C (de)
FI (1) FI79943C (de)
NO (1) NO823891L (de)
NZ (1) NZ202565A (de)
ZA (1) ZA828433B (de)

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FI79943C (fi) 1990-04-10
CA1198370A (en) 1985-12-24
US4606909A (en) 1986-08-19
FI823975A0 (fi) 1982-11-19
ATE30380T1 (de) 1987-11-15
AU9072282A (en) 1983-05-26
NZ202565A (en) 1987-03-06
FI823975L (fi) 1983-05-21
DK150008C (da) 1987-05-25
EP0080341A2 (de) 1983-06-01
DE80341T1 (de) 1983-10-27
EP0080341B1 (de) 1987-10-28
FI79943B (fi) 1989-12-29
DK516481A (da) 1983-05-21
JPH0478611B2 (de) 1992-12-11
ZA828433B (en) 1983-08-31
NO823891L (no) 1983-05-24
JPS5892610A (ja) 1983-06-02
AU563725B2 (en) 1987-07-23
DK150008B (da) 1986-11-17
EP0080341A3 (en) 1983-09-14

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