DE3381396D1 - Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okular-therapeutische mittel. - Google Patents
Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okular-therapeutische mittel.Info
- Publication number
- DE3381396D1 DE3381396D1 DE8383305184T DE3381396T DE3381396D1 DE 3381396 D1 DE3381396 D1 DE 3381396D1 DE 8383305184 T DE8383305184 T DE 8383305184T DE 3381396 T DE3381396 T DE 3381396T DE 3381396 D1 DE3381396 D1 DE 3381396D1
- Authority
- DE
- Germany
- Prior art keywords
- okular
- formulation
- therapeutic agents
- aqueous compositions
- ophthalmic aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/415,758 US4559343A (en) | 1982-09-07 | 1982-09-07 | Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3381396D1 true DE3381396D1 (de) | 1990-05-10 |
Family
ID=23647073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8383305184T Expired - Lifetime DE3381396D1 (de) | 1982-09-07 | 1983-09-06 | Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okular-therapeutische mittel. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4559343A (de) |
EP (1) | EP0105635B1 (de) |
JP (1) | JPS5973520A (de) |
AT (1) | ATE51522T1 (de) |
CA (1) | CA1217144A (de) |
DE (1) | DE3381396D1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4567183A (en) * | 1983-03-11 | 1986-01-28 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
US4682284A (en) * | 1984-12-06 | 1987-07-21 | American Telephone & Telegraph Co., At&T Bell Lab. | Queue administration method and apparatus |
US4728509A (en) * | 1985-08-19 | 1988-03-01 | Takeda Chemical Industries, Ltd. | Aqueous liquid preparation |
DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
US4753945A (en) * | 1986-02-19 | 1988-06-28 | Eye Research Institute Of Retina Foundation | Stimulation of tear secretion with phosphodiesterase inhibitors |
US5171566A (en) * | 1986-05-16 | 1992-12-15 | The Green Cross Corporation | Flurbiprofen derivative ophthalmic preparation |
US4778810A (en) * | 1987-01-08 | 1988-10-18 | Nastech Pharmaceutical Co., Inc. | Nasal delivery of caffeine |
JP2764261B2 (ja) * | 1987-03-17 | 1998-06-11 | リ−ドケミカル株式会社 | 外用消炎鎮痛剤 |
US5414011A (en) * | 1987-09-11 | 1995-05-09 | Syntex (U.S.A.) Inc. | Preservative system for ophthalmic formulations |
US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
US4996209A (en) * | 1988-06-20 | 1991-02-26 | Alcon Laboratories, Inc. | Ophthalmic antiinflammatory compositions comprising S(+)-flurbiprofen |
ES2012532A6 (es) * | 1988-07-15 | 1990-04-01 | Cusi Lab | Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica. |
US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
US5271939A (en) * | 1988-10-03 | 1993-12-21 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
US4939135A (en) * | 1988-10-03 | 1990-07-03 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
US5360611A (en) * | 1988-10-03 | 1994-11-01 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation |
US5124392A (en) * | 1988-10-03 | 1992-06-23 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
US5032575A (en) * | 1988-10-12 | 1991-07-16 | Eye Research Institute Of Retina Foundation, Inc. | Method for enhancing healing of corneal endothelial wounds |
US5036046A (en) * | 1988-10-12 | 1991-07-30 | Eye Research Institute Of Retina Foundation, Inc. | Method for enhancing healing of corneal endothelial wounds |
US5051443A (en) * | 1988-10-12 | 1991-09-24 | Eye Research Institute Of Retina Foundation, Inc. | Method for enhancing healing of corneal endothelial wounds |
US5013751A (en) * | 1989-01-10 | 1991-05-07 | Alcon Laboratories, Inc. | (+) Suprofen esters and amides as opthalmic anti-inflammatory agents |
US4988728A (en) * | 1989-11-03 | 1991-01-29 | Alcon Laboratories, Inc. | Suprofen esters and amides as ophthalmic anti-inflammatory agents |
US5124154A (en) * | 1990-06-12 | 1992-06-23 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
DE4037554A1 (de) * | 1990-11-26 | 1992-05-27 | Roemmers Sa | Arzneimittel zur topischen anwendung |
US5444076A (en) * | 1990-11-26 | 1995-08-22 | Roemmers S.A.I.C.F. | Pharmaceutical preparation for topical application |
US5281353A (en) * | 1991-04-24 | 1994-01-25 | Allergan, Inc. | Compositions and methods for disinfecting/cleaning of lenses and for destroying oxidative disinfectants |
NZ242358A (en) * | 1991-05-10 | 1994-03-25 | Allergan Inc | Use of thiol compounds to inhibit deposits on a contact lens |
US5340572A (en) * | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
US5624893A (en) * | 1993-10-14 | 1997-04-29 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation |
JP2742333B2 (ja) * | 1994-05-06 | 1998-04-22 | アルコン ラボラトリーズ,インコーポレイテッド | 眼科用組成物におけるビタミンeトコフェリル誘導体の使用 |
US6309630B1 (en) * | 1994-05-24 | 2001-10-30 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic suspensions |
US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
GB9613457D0 (en) * | 1996-06-27 | 1996-08-28 | Procter & Gamble | Pharmaceutical compositions |
US5814655A (en) * | 1996-11-14 | 1998-09-29 | Insite Vision Incorporated | Non-steroidal ophthalmic mixtures |
US6274592B1 (en) * | 1997-02-04 | 2001-08-14 | Senju Pharmaceutical Co., Ltd. | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid |
US6265444B1 (en) | 1997-05-23 | 2001-07-24 | Insite Vision Incorporated | Ophthalmic composition |
PE20020578A1 (es) | 2000-10-10 | 2002-08-14 | Upjohn Co | Una composicion de antibiotico topico para el tratamiento de infecciones oculares |
US20030220376A1 (en) * | 2001-08-10 | 2003-11-27 | Pharmacia Corporation | Methods for treating carbonic anhydrase mediated disorders |
MXPA04008173A (es) * | 2002-02-22 | 2004-11-26 | Pharmacia Corp | Formulaciones de farmaco antibiotico oftalmico que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio. |
US20030191187A1 (en) * | 2002-04-01 | 2003-10-09 | Lee Fang Yu | Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same |
US20040034042A1 (en) * | 2002-08-14 | 2004-02-19 | Masao Tsuji | Preservative composition |
WO2005102303A2 (en) * | 2004-04-21 | 2005-11-03 | Advanced Ocular Systems Limited | Antiprostaglandins for the treatment of ocular pathologies |
US20090092574A1 (en) | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
EA201391043A1 (ru) | 2011-02-17 | 2014-03-31 | Сентисс Фарма Прайвет Лимитед | Способ и композиция для замедления сорбции консервантов пластиками |
EP3505154B1 (de) * | 2017-12-26 | 2022-04-06 | Industrial Technology Research Institute | Zusammensetzung zur verbesserung der löslichkeit schwerlöslicher substanzen, ihre verwendung und diese enthaltende komplexe formulierung |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2994640A (en) * | 1957-02-22 | 1961-08-01 | Byk Gulden Lomberg Chem Fab | Anti-inflammatory therapy with purine molecular compounds |
US3439094A (en) * | 1967-07-20 | 1969-04-15 | Warner Lambert Pharmaceutical | Analgesic compositions containing namol xenyrate,caffeine and acetyl-rho-aminophenol |
DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
US3957994A (en) * | 1974-12-19 | 1976-05-18 | Nelson Research & Development Company | Topical anti-inflammatory composition and method of use |
US4144332A (en) * | 1976-01-05 | 1979-03-13 | The Regents Of The University Of Michigan | Process for alleviating proliferative skin diseases |
NL7707501A (nl) * | 1976-08-12 | 1978-02-14 | Knoll Ag | Uitwendig toe te dienen geneesmiddelpreparaat. |
JPS5697224A (en) * | 1979-12-28 | 1981-08-05 | Kaken Pharmaceut Co Ltd | Antipyretic analgesic composition |
JPS56154416A (en) * | 1980-04-30 | 1981-11-30 | Kaken Pharmaceut Co Ltd | Antipyretic analgesic composition |
JPS59501460A (ja) * | 1982-07-22 | 1984-08-16 | サンシヤイン,アブラハム | カフェインを含んで成る改良された鎮痛及び抗炎症組成物並びにその使用方法 |
US4420483A (en) * | 1982-07-22 | 1983-12-13 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same |
-
1982
- 1982-09-07 US US06/415,758 patent/US4559343A/en not_active Expired - Lifetime
-
1983
- 1983-09-05 JP JP58163099A patent/JPS5973520A/ja active Granted
- 1983-09-06 EP EP83305184A patent/EP0105635B1/de not_active Expired - Lifetime
- 1983-09-06 AT AT83305184T patent/ATE51522T1/de not_active IP Right Cessation
- 1983-09-06 DE DE8383305184T patent/DE3381396D1/de not_active Expired - Lifetime
- 1983-09-07 CA CA000436208A patent/CA1217144A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5973520A (ja) | 1984-04-25 |
US4559343A (en) | 1985-12-17 |
CA1217144A (en) | 1987-01-27 |
ATE51522T1 (de) | 1990-04-15 |
EP0105635A3 (en) | 1986-06-11 |
EP0105635A2 (de) | 1984-04-18 |
EP0105635B1 (de) | 1990-04-04 |
JPH0551568B2 (de) | 1993-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |