DE3474773D1 - Compositions useful for producing analgesia - Google Patents

Compositions useful for producing analgesia

Info

Publication number
DE3474773D1
DE3474773D1 DE8484304727T DE3474773T DE3474773D1 DE 3474773 D1 DE3474773 D1 DE 3474773D1 DE 8484304727 T DE8484304727 T DE 8484304727T DE 3474773 T DE3474773 T DE 3474773T DE 3474773 D1 DE3474773 D1 DE 3474773D1
Authority
DE
Germany
Prior art keywords
compositions useful
producing analgesia
analgesia
producing
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484304727T
Other languages
English (en)
Inventor
Thomas Robert Lahann
Brian Lee Buckwalter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE3474773D1 publication Critical patent/DE3474773D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
DE8484304727T 1983-07-14 1984-07-11 Compositions useful for producing analgesia Expired DE3474773D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/514,206 US4493848A (en) 1983-07-14 1983-07-14 Compositions and methods useful for producing analgesia

Publications (1)

Publication Number Publication Date
DE3474773D1 true DE3474773D1 (en) 1988-12-01

Family

ID=24046228

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484304727T Expired DE3474773D1 (en) 1983-07-14 1984-07-11 Compositions useful for producing analgesia

Country Status (15)

Country Link
US (1) US4493848A (de)
EP (1) EP0132113B1 (de)
JP (1) JPS6075429A (de)
AU (1) AU568550B2 (de)
CA (1) CA1244046A (de)
DE (1) DE3474773D1 (de)
DK (1) DK163958C (de)
GB (1) GB2144328B (de)
HK (1) HK87390A (de)
IE (1) IE57565B1 (de)
MY (1) MY101934A (de)
NZ (1) NZ208901A (de)
PH (1) PH22794A (de)
SG (1) SG32289G (de)
ZA (1) ZA845391B (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
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US4564633A (en) * 1983-07-14 1986-01-14 The Procter & Gamble Company Compositions and methods useful for producing analgesia
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4573995A (en) * 1984-10-09 1986-03-04 Alza Corporation Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine
US4898887A (en) * 1984-12-20 1990-02-06 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity
US5013759A (en) * 1985-06-10 1991-05-07 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity
GB2178031B (en) 1985-06-10 1989-07-26 Procter & Gamble Phenylacetic acid amides having anti-inflammatory and analgesic activity
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4990533A (en) * 1985-12-20 1991-02-05 Warner-Lambert Co. Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
WO1989004297A1 (en) * 1986-08-19 1989-05-18 Warner-Lambert Company 4'-hydroxybenzylamine derivatives having anti-inflammatory and analgesic activity
US4980366A (en) * 1986-08-19 1990-12-25 Warner-Lambert Co. Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
US5063060A (en) * 1989-12-19 1991-11-05 Cisco Limited Partnership Compositions and method for treating painful, inflammatory or allergic disorders
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5589480A (en) * 1994-08-17 1996-12-31 Elkhoury; George F. Topical application of opioid analgesic drugs such as morphine
US5866143A (en) * 1995-03-24 1999-02-02 El Khoury And Stein, Ltd. Topical application of opioid drugs such as morphine for relief of itching and skin disease
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US5856537A (en) * 1996-06-26 1999-01-05 The Scripps Research Institute Inhibitors of oleamide hydrolase
US5919473A (en) * 1997-05-12 1999-07-06 Elkhoury; George F. Methods and devices for delivering opioid analgesics to wounds via a subdermal implant
AU7389098A (en) 1997-05-16 1998-12-08 Brigham And Women's Hospital Local anesthetic formulations
GB9713484D0 (en) * 1997-06-27 1997-09-03 Smithkline Beecham Plc Neuroprotective vanilloid compounds
US6011022A (en) * 1998-03-03 2000-01-04 El Khoury; George F. Topical application of muscarinic analgesic drugs such as neostigmine
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6200604B1 (en) 1998-03-27 2001-03-13 Cima Labs Inc. Sublingual buccal effervescent
US6576250B1 (en) 1998-03-27 2003-06-10 Cima Labs Inc. Pharmaceutical compositions for rectal and vaginal administration
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US6689399B1 (en) 2000-03-16 2004-02-10 James R. Dickson Transdermal delivery of an anti-inflammatory composition
US7192612B2 (en) * 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
WO2002067966A1 (en) 2001-02-22 2002-09-06 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
AU2002355432A1 (en) * 2001-08-10 2003-02-24 Kava Pharmaceuticals, Inc. Kavalactone compositions and methods of use
EP1450824A4 (de) * 2001-11-02 2005-09-28 Elan Corp Plc Pharmazeutische zusammensetzung
GB0217056D0 (en) * 2002-07-23 2002-08-28 Ass Octel Use
EA012367B1 (ru) 2002-09-05 2009-10-30 Ньюроджескс, Инк. Композиция и способ очистки поверхности тела от капсаицина, набор и способ лечения боли
JP5189242B2 (ja) * 2002-09-23 2013-04-24 アルケルメス ファーマ アイルランド リミテッド 乱用抵抗性の医薬組成物
DK1605956T3 (en) 2002-12-18 2016-02-15 Ct Xion Therapeutics Corp ADMINISTRATION OF CAPSAICINOIDS TO TREAT OSTEOARTHRITIS
ES2311756T3 (es) * 2002-12-18 2009-02-16 Algorx Administracion de la capsiacina.
AU2004230915B2 (en) * 2003-04-08 2008-08-07 Algorx Pharmaceuticals, Inc. Preparation and purification of synthetic capsaicin
ES2535045T3 (es) 2003-04-10 2015-05-04 Vanderbilt Royalty Sub L.P. Usos y composiciones para administración de capsaicina
US7862833B2 (en) 2003-12-31 2011-01-04 Cima Labs, Inc. Effervescent oral opiate dosage forms and methods of administering opiates
US20070036853A1 (en) * 2003-12-31 2007-02-15 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
CA2548915C (en) * 2003-12-31 2012-10-16 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
ITMI20041566A1 (it) * 2004-07-30 2004-10-30 Indena Spa "trpv1 agonisti, formulazioni che li contengono e loro usi"
CA2596194A1 (en) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
US20080268092A1 (en) * 2004-12-01 2008-10-30 Dacanay Rhodel G Capsaicin Nutritional Supplement
CN101189000A (zh) * 2005-02-14 2008-05-28 纽罗吉斯克斯公司 Trpv1激动剂的递送装置
WO2006105481A1 (en) * 2005-03-30 2006-10-05 Neurogesx, Inc. Low-concentration capsaicin patch and methods for treating neuropathic pain
DE602006017345D1 (de) * 2005-04-01 2010-11-18 Neurogesx Inc Öle von capsaicinoiden und verfahren zu ihrer herstellung und verwendung
EP1879855A2 (de) * 2005-04-25 2008-01-23 Neurogesx, Inc. Trpv1-agonist-verbindungen und verfahren zu ihrer herstellung und verwendung
US7943666B2 (en) 2006-07-24 2011-05-17 Trinity Laboratories, Inc. Esters of capsaicin for treating pain
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
US8987328B2 (en) * 2008-10-30 2015-03-24 Trinity Laboratories, Inc. Esters of capsaicinoids as dietary supplements
US8957207B2 (en) 2009-03-24 2015-02-17 Proteus S.A. Methods for producing phycotoxins
DK2629610T3 (da) 2010-07-27 2017-11-20 Flex Pharma Inc Fremgangsmåder og sammensætninger til forebyggelse og lindring af muskelkramper og til rehabilitering fra neuromuskulær irritabilitet og træthed efter træning
EP2455066B1 (de) * 2010-11-08 2018-10-17 EPITECH GROUP S.p.A. Pharmakologische Zubereitung zur topischen Anwendung enthaltend N-Palmitoyl-Vanillamid
US20120310140A1 (en) 2010-12-01 2012-12-06 Spinal Modulation, Inc. Directed delivery of agents to neural anatomy
KR20210062693A (ko) 2013-03-15 2021-05-31 더 칠드런스 메디칼 센터 코포레이션 지속성 국소 마취용 네오삭시톡신 조합 제형
MX2019000860A (es) 2016-07-19 2019-06-03 Conagen Inc Metodo para la produccion microbiana de capsaicinoides naturales especificos.
JP6986084B2 (ja) 2016-12-22 2021-12-22 コナジェン・インコーポレイテッドConagen Inc. ８−メチルノナン酸の微生物生成方法
WO2018136943A1 (en) 2017-01-23 2018-07-26 Flex Pharma, Inc. Compositions and methods affecting exercise performance

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD75368A (de) *
DE938014C (de) * 1952-11-05 1956-01-19 Beiersdorf & Co A G P Verfahren zur Herstellung kristallisierter Vanillylamide
DE1166766B (de) * 1961-08-04 1964-04-02 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen Phenylalkylcarbonsaeureamiden
FR1336388A (fr) * 1961-08-04 1963-08-30 Boehringer Sohn Ingelheim Procédé pour la préparation des amides d'acides phénylalcoylcarboxyliques
BE626897A (de) * 1962-01-17
NL132935C (de) * 1964-12-04
US4238508A (en) * 1979-08-17 1980-12-09 The Research Foundation Of State University Of New York Method for analgesia using 3-hydroxyacetanilide
US4313958A (en) * 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
US4401663A (en) * 1981-06-30 1983-08-30 The Procter & Gamble Company Novel sulfonamide derivatives
US4544668A (en) * 1983-07-14 1985-10-01 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4544669A (en) * 1983-07-14 1985-10-01 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4532139A (en) * 1983-07-14 1985-07-30 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
JPS6139413A (ja) * 1984-07-31 1986-02-25 日立電線株式会社 弛度抑制型電線の製造方法
JPS6147752A (ja) * 1984-08-14 1986-03-08 Fujikura Ltd 難燃性組成物

Also Published As

Publication number Publication date
CA1244046A (en) 1988-11-01
JPS6075429A (ja) 1985-04-27
IE841812L (en) 1985-01-14
MY101934A (en) 1992-02-15
EP0132113A1 (de) 1985-01-23
DK163958C (da) 1992-09-21
US4493848A (en) 1985-01-15
PH22794A (en) 1988-12-12
AU568550B2 (en) 1988-01-07
DK163958B (da) 1992-04-27
NZ208901A (en) 1988-03-30
SG32289G (en) 1989-09-22
AU3058784A (en) 1985-01-17
DK345684A (da) 1985-01-15
ZA845391B (en) 1985-03-27
HK87390A (en) 1990-11-02
IE57565B1 (en) 1992-12-16
GB2144328A (en) 1985-03-06
EP0132113B1 (de) 1988-10-26
GB2144328B (en) 1987-01-21
GB8417623D0 (en) 1984-08-15
DK345684D0 (da) 1984-07-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee