DE3486254T2 - Verfahren zum aufspüren, identifizieren und quantifizieren von organismen und viren. - Google Patents

Verfahren zum aufspüren, identifizieren und quantifizieren von organismen und viren.

Info

Publication number
DE3486254T2
DE3486254T2 DE84900667T DE3486254T DE3486254T2 DE 3486254 T2 DE3486254 T2 DE 3486254T2 DE 84900667 T DE84900667 T DE 84900667T DE 3486254 T DE3486254 T DE 3486254T DE 3486254 T2 DE3486254 T2 DE 3486254T2
Authority
DE
Germany
Prior art keywords
detecting
viruses
identifying
organisms
quantifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE84900667T
Other languages
English (en)
Other versions
DE3486254D1 (de
Inventor
David E Kohne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23813907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3486254(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Publication of DE3486254D1 publication Critical patent/DE3486254D1/de
Application granted granted Critical
Publication of DE3486254T2 publication Critical patent/DE3486254T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
DE84900667T 1983-01-10 1984-01-09 Verfahren zum aufspüren, identifizieren und quantifizieren von organismen und viren. Revoked DE3486254T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45672983A 1983-01-10 1983-01-10
PCT/US1984/000016 WO1984002721A1 (en) 1983-01-10 1984-01-09 Method for detecting, identifying, and quantitating organisms and viruses

Publications (2)

Publication Number Publication Date
DE3486254D1 DE3486254D1 (de) 1994-01-20
DE3486254T2 true DE3486254T2 (de) 1994-05-05

Family

ID=23813907

Family Applications (4)

Application Number Title Priority Date Filing Date
DE3486488T Expired - Lifetime DE3486488T2 (de) 1983-01-10 1984-01-09 Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren
DE198484900667T Pending DE131052T1 (de) 1983-01-10 1984-01-09 Verfahren zum aufspueren, identifizieren und quantifizieren von organismen und viren.
DE84900667T Revoked DE3486254T2 (de) 1983-01-10 1984-01-09 Verfahren zum aufspüren, identifizieren und quantifizieren von organismen und viren.
DE3486467T Expired - Lifetime DE3486467T3 (de) 1983-01-10 1984-01-09 Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE3486488T Expired - Lifetime DE3486488T2 (de) 1983-01-10 1984-01-09 Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren
DE198484900667T Pending DE131052T1 (de) 1983-01-10 1984-01-09 Verfahren zum aufspueren, identifizieren und quantifizieren von organismen und viren.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3486467T Expired - Lifetime DE3486467T3 (de) 1983-01-10 1984-01-09 Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren

Country Status (11)

Country Link
US (1) US4851330A (de)
EP (3) EP0131052B1 (de)
JP (3) JPS60501339A (de)
AT (3) ATE167524T1 (de)
AU (3) AU2490284A (de)
CA (1) CA1215904A (de)
DE (4) DE3486488T2 (de)
DK (1) DK430384A (de)
FI (1) FI843529L (de)
NO (1) NO843574L (de)
WO (1) WO1984002721A1 (de)

Families Citing this family (229)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614361A (en) * 1981-09-25 1997-03-25 Webster, Jr.; John A. Method for identifying and characterizing organisms
US5482834A (en) * 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US5288611A (en) * 1983-01-10 1994-02-22 Gen-Probe Incorporated Method for detecting, identifying, and quantitating organisms and viruses
US5723597A (en) * 1983-01-10 1998-03-03 Gen-Probe Incorporated Ribosomal nucleic acid probes for detecting organisms or groups of organisms
US5641631A (en) * 1983-01-10 1997-06-24 Gen-Probe Incorporated Method for detecting, identifying, and quantitating organisms and viruses
EP0175776B1 (de) * 1984-04-05 1991-07-31 Howard Florey Institute Of Experimental Physiology And Medicine Hybridisierungs-histochemie
US4766062A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay method and polynucleotide complex reagent therefor
IL75648A0 (en) * 1984-07-05 1985-10-31 Gen Probe Inc Accelerated nucleic acid reassociation method
FR2568588B1 (fr) * 1984-08-02 1987-02-13 Inst Nat Sante Rech Med Sonde et procede pour la detection de micro-organismes determines, notamment des legionella dans les milieux les contenant
US5955261A (en) * 1984-09-04 1999-09-21 Gen-Probe Incorporated Method for detecting the presence of group-specific viral mRNA in a sample
IL76997A0 (en) * 1984-11-14 1986-04-29 Oncogene Science Inc Probes and methods useful for detecting chromosomal translocation
US4820630A (en) * 1984-11-23 1989-04-11 Digene Diagnostics, Incorporated Assay for nucleic acid sequences, particularly genetic lesions, using interactive labels
US4670379A (en) * 1984-12-19 1987-06-02 E. I. Du Pont De Nemours And Company Polynucleotide hydridization assays employing catalyzed luminescence
US4785086A (en) * 1985-01-17 1988-11-15 Integrated Genetics, Inc. Test for Campylobacter
US5851767A (en) * 1985-03-04 1998-12-22 The Regents Of The University Of California Detection of prokaryotic organism by DNA hybridization
US6040166A (en) 1985-03-28 2000-03-21 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences, including a probe
EP0219842A1 (de) * 1985-10-23 1987-04-29 Allied Corporation Nukleinsäuretest mittels Segmentpaarhemmung oder -konkurrenz
DE3687645T2 (de) * 1986-01-07 1993-05-27 Gen Probe Inc Verfahren der beschleunigten wiederassoziation der nukleinsaeure.
US5447848A (en) * 1986-01-22 1995-09-05 Amoco Corporation Detection of campylobacter with nucleic acid probes
EP0232085B1 (de) * 1986-01-22 1993-04-28 Amoco Corporation Campylobacter-Sonde
CA1296604C (en) * 1986-03-20 1992-03-03 Kathleen Murphy Method for releasing rna and dna from cells
FR2596774B1 (fr) * 1986-04-04 1988-07-22 Pasteur Institut Sondes oligonucleotidiques et procedes pour la detection par hybridation des acides nucleiques de bacteries et autres etres vivants
GB8608629D0 (en) * 1986-04-09 1986-05-14 Biotechnica Ltd Labelling
ATE110418T1 (de) * 1986-06-25 1994-09-15 Univ California Nachweis von mykoplasma durch hybridisierung von dns.
JP2870693B2 (ja) * 1986-06-30 1999-03-17 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ−・オブ・カリフオルニア オリゴヌクレオチドプローブ及びそれを用いて原核生物の存在を決定するための方法
WO1988000618A1 (en) * 1986-07-10 1988-01-28 Toray Industries, Inc. Method of inspecting specimen for bacteria and probe therefor
US5310650A (en) * 1986-09-29 1994-05-10 Abbott Laboratoires Method and device for improved reaction kinetics in nucleic acid hybridizations
US5994059A (en) * 1986-11-24 1999-11-30 Gen-Probe Incorporated Nucleic acid probes and methods for detecting Streptomyces enterococci
US7090972B1 (en) 1986-11-24 2006-08-15 Gen-Probe Incorporated Methods for determining the presence of non-viral organisms in a sample
US7087742B1 (en) 1986-11-24 2006-08-08 Gen-Probe Incorporated Oligonucleotide probes for the detection and/or quantitation of non-viral organisms
US6150517A (en) * 1986-11-24 2000-11-21 Gen-Probe Methods for making oligonucleotide probes for the detection and/or quantitation of non-viral organisms
ES2112824T5 (es) * 1986-11-24 2008-03-01 Gen-Probe Incorporated Sondas de acidos nucleicos para deteccion y/o cuantificacion de organismos no virales.
US5541308A (en) * 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
US5034314A (en) * 1986-12-22 1991-07-23 Olin Corporation Method and kit for separating double-stranded nucleic acid from a single-stranded/double-stranded mixture of nucleic acids
US5369005A (en) * 1987-01-09 1994-11-29 Board Of Regents, The University Of Texas System Method for mycoplasma detection in a biological sample
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
GB8709803D0 (en) * 1987-04-24 1987-05-28 Mcfadden J J Treatment of crohn's disease &c
US5225324A (en) * 1987-04-24 1993-07-06 Bioscience International, Inc. Diagnostics for mycobacteria in public health, medical, and veterinary practice
JPS6446650A (en) * 1987-08-18 1989-02-21 Tosoh Corp Nucleic acid hybridization assay method
US5089386A (en) * 1987-09-11 1992-02-18 Gene-Trak Systems Test for listeria
AU613989B2 (en) * 1987-11-24 1991-08-15 Gen-Probe Incorporated Means and method for enhancing nucleic acid hybridization
US5030557A (en) * 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
WO1989005359A1 (en) * 1987-12-01 1989-06-15 Integrated Genetics, Inc. Detection of salmonella
US5212059A (en) * 1988-01-11 1993-05-18 Microprobe Corporation Oligonucleotide probes for the detection of periodontal pathogens
WO1989006697A1 (en) * 1988-01-19 1989-07-27 The University Of Sydney Detection of cell death
ATE122103T1 (de) * 1988-03-28 1995-05-15 Amoco Corp Nachweis von eukaryotischen mikroorganismen.
US5294533A (en) * 1988-07-05 1994-03-15 Baylor College Of Medicine Antisense oligonucleotide antibiotics complementary to the macromolecular synthesis operon, methods of treating bacterial infections and methods for identification of bacteria
US7172863B1 (en) 1988-12-09 2007-02-06 Gen-Probe Incorporated Nucleic acid probes and methods for detecting Neisseria gonorrhoeae
SE8901188D0 (sv) * 1989-04-05 1989-04-05 Astra Ab A novel diagnostic method
CA2025236A1 (en) * 1989-02-06 1990-08-07 Walter King Probes and methods for the detection of listeria
IE81145B1 (en) * 1989-04-20 2000-05-03 Thomas Gerard Barry Generation of specific probes for target nucleotide sequences
DE69022167T2 (de) * 1989-05-23 1996-02-15 Amoco Corp Nukleinsäuresonden zum nachweis von staphylococcus aureus.
AU5950690A (en) * 1989-05-31 1991-01-07 Gene-Trak Systems Universal eubacteria nucleic acid probes and methods
US6589734B1 (en) * 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
US5856088A (en) * 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US5849504A (en) * 1989-08-11 1998-12-15 Amoco Corporation Nucleic acid probes and methods for detecting Pneumocystis carinii
AU6356390A (en) * 1989-08-11 1991-03-11 Gene-Trak Systems Nucleic acid probes for the detection of (pneumocystis carinii)
US5571674A (en) * 1989-09-18 1996-11-05 The Trustees Of Columbia University In The City Of New York DNA oligomers for use in detection of campylobacter pylori and methods of using such DNA oligomers
CA2025181A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting fungi
US5721097A (en) * 1990-02-02 1998-02-24 N. V. Innogenetics S.A. Hybridization probes for the detection of branhamella catarrhalis strains
US5912117A (en) * 1990-03-07 1999-06-15 Roche Molecular Systems, Inc. Method for diagnosis of lyme disease
AU7429591A (en) * 1990-04-18 1991-10-24 Gene-Trak Systems Nucleic acid probes for the detection of giardia lamblia
DE4014845A1 (de) * 1990-05-09 1991-11-14 Bayer Ag Verfahren zur detektion und quantitativen bestimmung von nitrosomonas-staemmen in abwaessern oder boeden
US5620847A (en) * 1990-10-05 1997-04-15 Hoffman-La Roche Inc. Methods and reagents for detection of bacteria in cerebrospinal fluid
US5635348A (en) * 1990-10-05 1997-06-03 Hoffmann-La Roche Inc. Method and probes for identifying bacteria found in blood
US5491225A (en) * 1991-12-19 1996-02-13 Hoffmann-La Roche Inc. PCR primers for detection of legionella species and methods for controlling visual intensity in hybridization assays
US5472843A (en) * 1991-04-25 1995-12-05 Gen-Probe Incorporated Nucleic acid probes to Haemophilus influenzae
US6028187A (en) * 1991-08-01 2000-02-22 Gen-Probe Incorporated Nucleic acid probes to Listeria monocytogenes
WO1993003184A1 (en) * 1991-08-09 1993-02-18 Mccann Associates, Inc. Method for detecting lyme disease and composition
US5422242A (en) * 1991-08-15 1995-06-06 Hoffmann-La Roche Inc. Mycobacterium primers and probes
US5292874A (en) * 1991-09-04 1994-03-08 Gen-Probe Incorporated Nucleic acid probes to Staphylococcus aureus
US5738987A (en) * 1991-09-04 1998-04-14 Gen-Probe Incorporated 16S ribosomal nucleic acid probes to streptococcus pneumoniae
US5558990A (en) * 1991-12-18 1996-09-24 Gen-Probe Incorporated Nucleic acid probes to blastomyces dermatitidis and paracoccidioides brasiliensis
US5284747A (en) * 1991-12-18 1994-02-08 Gen-Probe Incorporated Nucleic acid probes to Coccidioides immitis
US6300058B1 (en) 1992-01-29 2001-10-09 Hitachi Chemical Research Center, Inc. Method for measuring messenger RNA
US6100099A (en) * 1994-09-06 2000-08-08 Abbott Laboratories Test strip having a diagonal array of capture spots
US6232061B1 (en) 1992-04-01 2001-05-15 Cambridge Neuroscience, Inc. Homology cloning
CA2134357C (en) * 1992-04-28 2009-01-06 Philip W. Hammond Nucleic acid probes to mycobacterium tuberculosis
US6093538A (en) * 1992-05-06 2000-07-25 Gen-Probe Incorporated Nucleic acid probes to ureaplasma
DE69316801T2 (de) * 1992-07-20 1998-05-20 Yakult Honsha Kk Spezies-Spezifische Oligonukleotide gegen Bifidobakterien und Verfahren zum Nachweis unter Verwendung derselben
US5580971A (en) * 1992-07-28 1996-12-03 Hitachi Chemical Company, Ltd. Fungal detection system based on rRNA probes
JPH07509361A (ja) * 1992-07-28 1995-10-19 日立化成工業株式会社 遺伝子検出システム
US5374718A (en) * 1992-08-26 1994-12-20 Gen-Probe Incorporated Nucleic acid probes to chlamydia pneumoniae
JP2558420B2 (ja) * 1992-10-23 1996-11-27 扶桑薬品工業株式会社 感染症診断用プローブ
AU686616B2 (en) 1993-03-26 1998-02-12 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US6495676B1 (en) 1993-04-13 2002-12-17 Naxcor Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
US5767259A (en) 1994-12-27 1998-06-16 Naxcor Oligonucleotides containing base-free linking groups with photoactivatable side chains
US6277570B1 (en) 1993-04-13 2001-08-21 Naxcor Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
US5616464A (en) * 1994-12-27 1997-04-01 Naxcor Nucleic acid sequence detection employing amplification probes
WO1994028174A1 (en) * 1993-05-24 1994-12-08 Amoco Corporation Nucleic acid probes for bacteria of the genus legionella
US5550040A (en) 1993-06-23 1996-08-27 Hoffman-La Roche Inc. Method, reagents and kits for the detection of Neisseria gonorrhoeae
US5739309A (en) * 1993-07-19 1998-04-14 Gen-Probe Incorporated Enhancement of oligonucleotide inhibition of protein production, cell proliferation and / or multiplication of infectious disease pathogens
JPH09501562A (ja) * 1993-07-19 1997-02-18 ジェン−プローブ・インコーポレイテッド ヒト・免疫不全ウイルスに対する活性を有するオリゴヌクレオチド
AU7551094A (en) 1993-07-23 1995-02-20 Hyseq, Inc. Method for screening unknown organisms
US6136529A (en) * 1993-09-03 2000-10-24 Gen-Probe Incorporated Nucleic acid probes to Mycobacterium avium complex
US5484909A (en) * 1993-09-10 1996-01-16 Amoco Corporation Nucleic acid probes for the detection of bacteria of the genera Pediococcus and Lactobacillus and methods for the detection of the bacterial agents causing spoilage of beer
US5582978A (en) * 1994-01-21 1996-12-10 Amoco Corporation Nucleic acid probes for the detection of Haemophilus influenzae
JPH10500310A (ja) 1994-05-19 1998-01-13 ダコ アクティーゼルスカブ 淋菌及びトラコーマ クラミジアの検出のためのpna プローブ
US5712095A (en) * 1994-06-16 1998-01-27 Becton Dickinson And Company Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors
US5656427A (en) * 1994-08-29 1997-08-12 Gen-Probe Incorporated Nucleic acid hybridization assay probes, helper probes and amplification oligonucleotides targeted to Mycoplasma pneumoniae nucleic acid
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
US5763169A (en) * 1995-01-13 1998-06-09 Chiron Diagnostics Corporation Nucleic acid probes for the detection and identification of fungi
US6180339B1 (en) 1995-01-13 2001-01-30 Bayer Corporation Nucleic acid probes for the detection and identification of fungi
US5707802A (en) * 1995-01-13 1998-01-13 Ciba Corning Diagnostics Corp. Nucleic acid probes for the detection and identification of fungi
DK0805876T3 (da) * 1995-01-19 2000-11-06 Gen Probe Inc Nukleinsyreamplifikationsoligonukleotider og prober til Lyme-sygdom-associeret Borrelia
US5622827A (en) * 1995-02-07 1997-04-22 Gen-Probe Incorporated Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid
US5747252A (en) 1995-06-07 1998-05-05 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for Neisseria species
US5739311A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases
US5652126A (en) * 1995-06-07 1997-07-29 Gen-Probe Incorporated Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5731150A (en) * 1995-11-01 1998-03-24 Chiron Diagnostic Corporation IS6110 based molecular detection of mycobacterium tuberculosis
US5888733A (en) * 1995-11-16 1999-03-30 Dako A/S In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
US6218107B1 (en) 1996-05-22 2001-04-17 Gen-Probe Incorporated Compositions and methods for detecting the presence of Mycobacterium kansassii
EP0822261B1 (de) * 1996-07-29 2002-07-03 Academia Sinica Verfahren zur schnellen antimikrobiellen Empfindlichkeitsnachweis
US6110676A (en) * 1996-12-04 2000-08-29 Boston Probes, Inc. Methods for suppressing the binding of detectable probes to non-target sequences in hybridization assays
CA2286864A1 (en) 1997-01-10 1998-07-16 Pioneer Hi-Bred International, Inc. Hybridization-based genetic amplification and analysis
NO974299D0 (no) * 1997-09-18 1997-09-18 Forskningsparken I Aas As Metode for stabil merking av mikroorganismer
US6962778B1 (en) 1997-09-25 2005-11-08 Boston Probes, Inc. Methods, kits and compositions for suppressing the binding of detectable probes to non-target sequences in hybridization assays
JP2002508190A (ja) * 1997-12-12 2002-03-19 ダイジーン・コーポレーション 万能収集媒質
US7399589B2 (en) * 1998-02-06 2008-07-15 Digene Corporation Immunological detection of RNA:DNA hybrids on microarrays
EP1614475B1 (de) 1998-05-01 2007-05-30 Gen-Probe Incorporated Rührvorrichtung für den fluiden Inhalt eines Behälters
US6664045B1 (en) 1998-06-18 2003-12-16 Boston Probes, Inc. PNA probes, probe sets, methods and kits pertaining to the detection of microorganisms
JP2002518026A (ja) * 1998-06-19 2002-06-25 エムティー テクノロジー, インコーポレイテッド Srprnaを用いる非ウイルス生物の検出
AU6412799A (en) 1998-10-05 2000-04-26 Mosaic Technologies Reverse displacement assay for detection of nucleic acid sequences
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
US6797817B1 (en) 1999-04-15 2004-09-28 E. I. Du Pont De Nemours And Company Nucleic acid fragments for the identification of dechlorinating bacteria
US6894156B2 (en) * 1999-04-15 2005-05-17 E. I. Du Pont De Nemours And Company Nucleic acid fragments for the identification of dechlorinating bacteria
US6469156B1 (en) 1999-04-20 2002-10-22 The United States Of America As Represented By The Department Of Health And Human Services Rapid and sensitive method for detecting histoplasma capsulatum
US6821770B1 (en) * 1999-05-03 2004-11-23 Gen-Probe Incorporated Polynucleotide matrix-based method of identifying microorganisms
CA2370123C (en) 1999-05-03 2010-09-14 Gen-Probe Incorporated Polynucleotide probes for detection and quantitation of actinomycetes
DK1177317T3 (da) 1999-05-03 2006-12-11 Gen Probe Inc Polynukleotidprober til eksklusiv sporing og kvantisering af staphy-lococcus
WO2000066785A2 (en) 1999-05-03 2000-11-09 Gen-Probe Incorporated Polynucleotide probes for detection and quantitation of bacteria in the family enterobacteriaceae
US6738502B1 (en) 1999-06-04 2004-05-18 Kairos Scientific, Inc. Multispectral taxonomic identification
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
GB0016814D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (3)
EP1356103B1 (de) * 2000-09-12 2010-10-20 Gen-Probe Incorporated Zusammensetzungen, methoden und testssysteme zur bestimmung der präsenz von cryptosporidium organismen in einer testprobe
DE10050135A1 (de) * 2000-10-11 2002-04-18 Biochem Labor Fuer Biolog Und Verfahren zur Sterilitätsprüfung von insbesondere flüssigen Medien
US8214153B1 (en) 2001-01-26 2012-07-03 Technology Licensing Co. Llc Methods for determining the genetic affinity of microorganisms and viruses
AU2002305941A1 (en) * 2001-03-01 2002-09-19 The Johns Hopkins University Quantitative assay for the simultaneous detection and speciation of bacterial infections
US20030027135A1 (en) * 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
KR100436554B1 (ko) * 2001-04-17 2004-06-18 삼성전자주식회사 혼성화된 핵산의 검출감도를 증가시키는 방법
JP2003189869A (ja) * 2001-12-27 2003-07-08 Nisshinbo Ind Inc 被検体中に含まれる生物種を判定する方法およびそれに用いるキット
JP4560285B2 (ja) * 2002-10-02 2010-10-13 栄研化学株式会社 核酸沈澱剤を利用した核酸増幅産物のハイブリダイゼーションアッセイ
WO2004053155A1 (en) 2002-12-06 2004-06-24 Roche Diagniostics Gmbh Multiplex assay detection of pathogenic organisms
US7718361B2 (en) 2002-12-06 2010-05-18 Roche Molecular Systems, Inc. Quantitative test for bacterial pathogens
WO2005017488A2 (en) * 2003-01-23 2005-02-24 Science Applications International Corporation Method and system for identifying biological entities in biological and environmental samples
AU2004276722B2 (en) 2003-05-19 2009-03-12 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of trichomonas vaginalis in a test sample
CA2599576C (en) 2005-03-10 2015-09-15 Gen-Probe Incorporated Systems and methods to perform assays for detecting or quantifying analytes within samples
EP2348320B1 (de) 2005-03-10 2024-05-01 Gen-Probe Incorporated Verfahren und Systeme zur Erkennung mehrerer Fluoreszenzemissionssignale
EP1888772A1 (de) 2005-05-18 2008-02-20 Decode Genetics EHF. Varianten bei chr8q24.21 vermitteln krebsrisiko
WO2006133385A2 (en) * 2005-06-06 2006-12-14 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of chlamydophila pneumoniae in a test sample
CN101238222B (zh) * 2005-06-20 2013-04-10 解码遗传学私营有限责任公司 作为2型糖尿病风险诊断标记物的tcf7l2基因的遗传变异体
JP4934679B2 (ja) * 2005-12-27 2012-05-16 サムスン エレクトロニクス カンパニー リミテッド 9種の呼吸器疾患と関連するバクテリア種を特異的に検出するためのプライマー、プローブ、マイクロアレイおよびその方法
WO2008100244A2 (en) 2006-01-27 2008-08-21 Athena Diagnostics, Inc. Methods of detecting mutations associated with ataxia-ocular apraxia 2 (aoa2)
WO2007120869A2 (en) * 2006-04-14 2007-10-25 University Of South Florida Molecular detection and quantification of enterococci
KR100923303B1 (ko) * 2006-09-28 2009-10-23 삼성전자주식회사 10 종의 호흡기 질환을 야기시키는 박테리아의 표적 서열을 증폭시킬 수 있는 프라이머 세트, 10 종의 박테리아의 표적 서열에 특이적으로 혼성화하는 프로브 세트, 상기 프로브 세트가 고정화되어 있는 마이크로어레이 및 상기 프로브 세트를 이용하여 10 종의 박테리아의 존재를 검출하는 방법
KR100868765B1 (ko) * 2006-09-29 2008-11-17 삼성전자주식회사 항생제 내성 박테리아의 표적 서열을 증폭시킬 수 있는프라이머 세트, 박테리아의 표적 서열에 특이적으로혼성화하는 프로브 세트, 상기 프로브 세트가 고정화되어있는 마이크로어레이 및 상기 프로브 세트를 이용하여박테리아의 존재를 검출하는 방법
EP2099937A2 (de) * 2006-11-30 2009-09-16 Decode Genetics EHF Genetische suszeptibilitätsvarianten von diabetes mellitus typ 2
BRPI0720116B8 (pt) * 2006-12-05 2021-07-27 Decode Genetics Ehf método para determinar uma suscetibilidade à arritmia cardíaca ou acidente vascular cerebral em um indivíduo humano, uso de uma sonda de oligonucleotídeo, e, aparelho para determinar um indicador genético para a arritmia cardíaca e/ou acidente vascular cerebral em um indivíduo humano
SG193026A1 (en) 2007-02-07 2013-09-30 Decode Genetics Ehf Genetic variants contributing to risk of prostate cancer
AU2008218542B2 (en) * 2007-02-21 2014-06-26 Decode Genetics Ehf. Genetic susceptibility variants associated with cardiovascular disease
DK2155907T3 (da) * 2007-04-30 2015-08-31 Decode Genetics Ehf Genetiske varianter nyttige til risikovurdering af koronararteriesygdom og myokardieinfarkt
AU2008310530A1 (en) * 2007-10-12 2009-04-16 Decode Genetics Ehf Sequence variants for inferring human pigmentation patterns
US20100273162A1 (en) * 2007-10-17 2010-10-28 Sailaja Chandrapati Rapid detection of microorganisms
US8697360B2 (en) 2007-11-30 2014-04-15 Decode Genetics Ehf. Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition
JP5503552B2 (ja) 2007-12-21 2014-05-28 バイオメリュー・エスエイ メチシリン耐性黄色ブドウ球菌の検出
AU2009213689B2 (en) * 2008-02-14 2014-11-20 Decode Genetics Ehf. Susceptibility variants for lung cancer
NZ588905A (en) 2008-04-01 2012-08-31 Decode Genetics Ehf Genetic testing method for determining susceptibility to abdominal aortic aneurysm by assay for selected polymorphisms associated with the disease
JP2012506705A (ja) * 2008-10-27 2012-03-22 キアジェン ゲイサーズバーグ インコーポレイテッド 迅速に結果を得るハイブリッドキャプチャー法による分析およびシステム
WO2010067381A1 (en) * 2008-12-12 2010-06-17 Decode Genetics Ehf Genetic variants as markers for use in diagnosis, prognosis and treatment of eosinophilia, asthma, and myocardial infarction
WO2010088292A1 (en) * 2009-01-28 2010-08-05 Qiagen Gaithersburg, Inc. Sequence-specific large volume sample preparation method and assay
CA2760542A1 (en) 2009-05-01 2010-11-04 Qiagen Gaithersburg, Inc. A non-target amplification method for detection of rna splice-forms in a sample
US8628924B2 (en) 2009-07-21 2014-01-14 Gen-Probe Incorporated Methods and compositions for quantitative amplification and detection over a wide dynamic range
US8614062B1 (en) 2009-07-24 2013-12-24 University Of South Florida RNA-based system and method to differentiate seafood
AU2010291990B2 (en) 2009-09-14 2016-05-05 Qiagen Gaithersburg, Inc. Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media
AU2010339861A1 (en) 2009-12-21 2012-10-25 Becton, Dickinson And Company Methods for identifying drug resistant Mycobacterium
US9404160B2 (en) 2009-12-22 2016-08-02 Becton, Dickinson And Company Methods for the detection of microorganisms
US8790879B2 (en) 2010-01-22 2014-07-29 Gen-Probe Incorporated Probes for detecting the presence of Trichomonas vaginalis in a sample
CN102822189B (zh) 2010-01-29 2016-06-29 奇亚根盖瑟斯堡股份有限公司 用于核酸的序列特异性纯化和多重复合体分析(multiplex analysis)的方法和组合物
BR112012018545A2 (pt) 2010-01-29 2016-05-03 Qiagen Gaithersburg Inc método de determinação e confirmação da presença de um hpv em uma amostra
US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
CA2799200A1 (en) 2010-05-19 2011-11-24 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー. 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
EP2749887A3 (de) 2010-07-23 2014-10-01 Beckman Coulter, Inc. System oder Verfahren zur Aufnahme analytischer Einheiten
US20130315934A1 (en) 2010-10-28 2013-11-28 Yale University Methods and Compositions for Assessing and Treating Cancer
WO2012071525A2 (en) 2010-11-24 2012-05-31 Yale University Compositions and methods for diagnosing and treating diseases and disorders associated with d-dt
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
US9885092B2 (en) 2011-02-24 2018-02-06 Qiagen Gaithersburg Inc. Materials and methods for detection of HPV nucleic acids
AU2012222178B2 (en) 2011-02-24 2014-12-18 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
WO2012178007A1 (en) 2011-06-22 2012-12-27 Yale University COMPOSITIONS AND METHODS OF DIAGNOSING DISEASES AND DISORDERS ASSOCIATED WITH β CELL DEATH
JP2014532881A (ja) 2011-11-07 2014-12-08 ベックマン コールター, インコーポレイテッド 標本輸送システムのための磁気制動
EP3373015A1 (de) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotierungssystem und arbeitsablauf
BR112014010955A2 (pt) 2011-11-07 2017-06-06 Beckman Coulter Inc sistema e método para processar amostras
BR112014011043A2 (pt) 2011-11-07 2017-06-13 Beckman Coulter Inc detecção de recipiente de espécime
US9482684B2 (en) 2011-11-07 2016-11-01 Beckman Coulter, Inc. Centrifuge system and workflow
US9446418B2 (en) 2011-11-07 2016-09-20 Beckman Coulter, Inc. Robotic arm
EP2794917B1 (de) 2011-12-23 2018-08-08 bioMérieux Nachweis von meca-varianten-stämmen von methicillin-resistentem staphylococcus aureus
CN104169719B (zh) 2011-12-29 2017-03-08 思迪赛特诊断有限公司 用于检测生物样品中病原体的方法和系统
WO2013166460A1 (en) 2012-05-04 2013-11-07 The Regents Of The University Of California Antibiotic susceptibility testing using probes for preribosomal rna
US10472683B2 (en) 2012-06-01 2019-11-12 Akron Biotechnology, LLC. Detection of Mycoplasma in cell cultures and cell culture derived biologicals
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
US9551704B2 (en) 2012-12-19 2017-01-24 Dna Electronics, Inc. Target detection
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
US9434940B2 (en) 2012-12-19 2016-09-06 Dna Electronics, Inc. Methods for universal target capture
AU2013202788B2 (en) 2013-03-14 2015-10-01 Gen-Probe Incorporated Indexing signal detection module
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
AU2014286889B2 (en) * 2013-07-03 2019-05-23 Qvella Corporation Methods of targeted antibiotic susceptibility testing
EP3800267A1 (de) 2014-03-27 2021-04-07 Yale University Zirkulierende mikro-rnas als biomarker für endometriose
AU2015273443B2 (en) 2014-06-13 2021-03-04 Q-Linea Ab Method for detecting and characterising a microorganism
WO2016164407A2 (en) 2015-04-07 2016-10-13 Polyskope Labs Detection of one or more pathogens
GB201507026D0 (en) 2015-04-24 2015-06-10 Linea Ab Q Medical sample transportation container
AU2016322966B2 (en) 2015-09-17 2021-10-14 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
CA3018536A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Distinguishing between blood sample components
GB2554767A (en) 2016-04-21 2018-04-11 Q Linea Ab Detecting and characterising a microorganism
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
AU2017263807B2 (en) 2016-05-11 2023-02-02 S.D. Sight Diagnostics Ltd Performing optical measurements on a sample
WO2018098241A1 (en) 2016-11-22 2018-05-31 University Of Rochester Methods of assessing risk of recurrent prostate cancer
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics
EP3710810B1 (de) 2017-11-14 2023-09-06 S.D. Sight Diagnostics Ltd. Probenträger für optische messungen
WO2019116234A1 (en) 2017-12-12 2019-06-20 Nestec S.A. Methods for determining microbiome ribosomal rna composition changes
EP3841223A1 (de) 2018-08-08 2021-06-30 Gen-Probe Incorporated Zusammensetzungen, verfahren und kits zum nachweis von mycoplasma genitalium
US20220298548A1 (en) 2019-08-23 2022-09-22 Gen-Probe Incorporated Compositions, methods and kits for detecting treponema pallidum
CA3153514A1 (en) 2019-09-05 2021-03-11 Gen-Probe Incorporated Detection of chlamydia trachomatis nucleic acid variants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US435835A (en) * 1890-09-02 Adolph w
US4302204A (en) * 1979-07-02 1981-11-24 The Board Of Trustees Of Leland Stanford Junior University Transfer and detection of nucleic acids
US4228238A (en) * 1979-08-23 1980-10-14 The Allor Foundation Method of laboratory testing in water-based culture media for zones of inhibition
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4416988A (en) * 1980-12-23 1983-11-22 Harvey Rubin Detection and isolation of enkephalin mRNA using a synthetic oligodeoxynucleotide
EP0155359B1 (de) * 1981-09-25 1988-01-07 John A. Webster, Jr. Verfahren zur Identifizierung und Charakterisierung von Organismen
ATE39267T1 (de) * 1981-09-25 1988-12-15 John A Webster Jr Verfahren zur identifizierung und charakterisierung von organismen.
US4717653A (en) * 1981-09-25 1988-01-05 Webster John A Jr Method for identifying and characterizing organisms
WO1984001174A1 (en) * 1982-09-20 1984-03-29 Harvard College Identification of microorganisms
US4699877A (en) * 1982-11-04 1987-10-13 The Regents Of The University Of California Methods and compositions for detecting human tumors

Also Published As

Publication number Publication date
EP0531798B2 (de) 2003-12-17
ATE202801T1 (de) 2001-07-15
DE3486467T2 (de) 1998-12-03
JPH05211896A (ja) 1993-08-24
JPH0771519B2 (ja) 1995-08-02
JPH0578319B2 (de) 1993-10-28
DE131052T1 (de) 1987-03-19
DK430384A (da) 1984-10-29
DK430384D0 (da) 1984-09-07
AU625739B2 (en) 1992-07-16
JP2976406B2 (ja) 1999-11-10
DE3486488D1 (de) 2001-08-09
EP0531798B1 (de) 1998-06-17
EP0131052A4 (de) 1987-09-08
FI843529A0 (fi) 1984-09-10
NO843574L (no) 1984-09-07
AU2846089A (en) 1989-05-11
EP0756010A3 (de) 1998-12-23
DE3486467T3 (de) 2004-10-14
WO1984002721A1 (en) 1984-07-19
FI843529L (fi) 1984-09-10
EP0131052B1 (de) 1993-12-08
EP0131052A1 (de) 1985-01-16
DE3486254D1 (de) 1994-01-20
EP0531798A3 (de) 1994-03-02
DE3486488T2 (de) 2003-04-03
ATE167524T1 (de) 1998-07-15
EP0756010B1 (de) 2001-07-04
DE3486467D1 (de) 1998-07-23
AU2490284A (en) 1984-08-02
EP0756010A2 (de) 1997-01-29
JPH08266299A (ja) 1996-10-15
AU605743B2 (en) 1991-01-24
AU5744786A (en) 1986-09-18
EP0531798A2 (de) 1993-03-17
US4851330A (en) 1989-07-25
JPS60501339A (ja) 1985-08-22
ATE98300T1 (de) 1993-12-15
CA1215904A (en) 1986-12-30

Similar Documents

Publication Publication Date Title
DE3486254T2 (de) Verfahren zum aufspüren, identifizieren und quantifizieren von organismen und viren.
ES2143680T3 (es) Metodo para caracterizar dna genomico.
DE3481775D1 (de) Verfahren zum raschen nachweis von mikroorganismen in klinischen proben.
DE3673501D1 (de) Mittel und verfahren zur funktionalisierung von nukleinsaeuren.
ATA64388A (de) Verbessertes verfahren zum nachweis von nucleinsaeuren und reagenzienkombination und besteck zu seiner durchfuehrung
DE3586629T2 (de) Nukleotidanaloga zur markierung von nukleinsaeuren und nachweis.
DE3483912D1 (de) Verfahren zur identifizierung und charakterisierung von organismen.
DE3689412T3 (de) Verfahren zur durchführung von hybridisierungstests von nukleinsäuren.
DE3575621D1 (de) Verfahren und anordnung zum kennzeichnen und erkennen von gegenstaenden.
ATE39267T1 (de) Verfahren zur identifizierung und charakterisierung von organismen.
DE3675400D1 (de) Verfahren und vorrichtung zum identifizieren von viren.
DE59204886D1 (de) Immobilisierung von Nukleinsäuren
DE69515416T2 (de) Verfahren zum Nachweis von Interferonaktivität
DE3784702T2 (de) Verfahren und vorrichtung zum nachweis und zur mengenbestimmung von bakterien.
DE3889232D1 (de) Verfahren zum quantitativen Nachweis von Sauerstoff.
DE3674802D1 (de) Verfahren zum nachweis von proteinen und viren.
ATE98701T1 (de) Verfahren zur durchfuehrung von hybridisierungstests von nukleinsaeuren.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee
8370 Indication related to discontinuation of the patent is to be deleted
8331 Complete revocation