DE3582193D1 - Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung. - Google Patents

Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung.

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Publication number
DE3582193D1
DE3582193D1 DE8585810213T DE3582193T DE3582193D1 DE 3582193 D1 DE3582193 D1 DE 3582193D1 DE 8585810213 T DE8585810213 T DE 8585810213T DE 3582193 T DE3582193 T DE 3582193T DE 3582193 D1 DE3582193 D1 DE 3582193D1
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DE
Germany
Prior art keywords
active agent
production
devices containing
gradient
constant release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE8585810213T
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English (en)
Inventor
Ping I Dr Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
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Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
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Publication of DE3582193D1 publication Critical patent/DE3582193D1/de
Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
DE8585810213T 1984-05-10 1985-05-07 Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung. Expired - Lifetime DE3582193D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/608,756 US4624848A (en) 1984-05-10 1984-05-10 Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use

Publications (1)

Publication Number Publication Date
DE3582193D1 true DE3582193D1 (de) 1991-04-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585810213T Expired - Lifetime DE3582193D1 (de) 1984-05-10 1985-05-07 Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung.

Country Status (16)

Country Link
US (1) US4624848A (de)
EP (1) EP0164311B1 (de)
JP (1) JPS619A (de)
AT (1) ATE61731T1 (de)
AU (1) AU583507B2 (de)
CA (1) CA1246447A (de)
DE (1) DE3582193D1 (de)
DK (1) DK205185A (de)
ES (1) ES8603273A1 (de)
FI (1) FI851801L (de)
GR (1) GR851114B (de)
IL (1) IL75129A (de)
NZ (1) NZ212030A (de)
PH (1) PH24100A (de)
PT (1) PT80416B (de)
ZA (1) ZA853511B (de)

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Also Published As

Publication number Publication date
AU583507B2 (en) 1989-05-04
EP0164311A2 (de) 1985-12-11
IL75129A (en) 1989-08-15
CA1246447A (en) 1988-12-13
NZ212030A (en) 1988-01-08
AU4221685A (en) 1985-11-14
GR851114B (de) 1985-11-25
ATE61731T1 (de) 1991-04-15
EP0164311B1 (de) 1991-03-20
ES542948A0 (es) 1986-01-01
DK205185A (da) 1985-11-11
EP0164311A3 (en) 1987-06-03
DK205185D0 (da) 1985-05-09
PT80416B (en) 1987-04-16
PT80416A (en) 1985-06-01
PH24100A (en) 1990-03-05
IL75129A0 (en) 1985-09-29
FI851801A0 (fi) 1985-05-08
JPS619A (ja) 1986-01-06
ZA853511B (en) 1985-12-24
US4624848A (en) 1986-11-25
ES8603273A1 (es) 1986-01-01
FI851801L (fi) 1985-11-11

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