DE3587804T2 - Testverfahren. - Google Patents

Testverfahren.

Info

Publication number
DE3587804T2
DE3587804T2 DE3587804T DE3587804T DE3587804T2 DE 3587804 T2 DE3587804 T2 DE 3587804T2 DE 3587804 T DE3587804 T DE 3587804T DE 3587804 T DE3587804 T DE 3587804T DE 3587804 T2 DE3587804 T2 DE 3587804T2
Authority
DE
Germany
Prior art keywords
enzyme
electrode
transfer
electron
electrochemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3587804T
Other languages
English (en)
Other versions
DE3587804D1 (de
Inventor
Simon John Rattle
Grenville Arthur Robinson
Gordon Coulter Forrest
Hugh Allen Oliver Hill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Serono SA
Original Assignee
Biochem Immunosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochem Immunosystems Ltd filed Critical Biochem Immunosystems Ltd
Application granted granted Critical
Publication of DE3587804D1 publication Critical patent/DE3587804D1/de
Publication of DE3587804T2 publication Critical patent/DE3587804T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/817Enzyme or microbe electrode
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/806Electrical property or magnetic property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
DE3587804T 1984-01-26 1985-01-25 Testverfahren. Expired - Lifetime DE3587804T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848402058A GB8402058D0 (en) 1984-01-26 1984-01-26 Methods of assay

Publications (2)

Publication Number Publication Date
DE3587804D1 DE3587804D1 (de) 1994-06-01
DE3587804T2 true DE3587804T2 (de) 1994-08-18

Family

ID=10555569

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3587804T Expired - Lifetime DE3587804T2 (de) 1984-01-26 1985-01-25 Testverfahren.

Country Status (9)

Country Link
US (1) US5149630A (de)
EP (1) EP0150999B1 (de)
JP (1) JPH07107530B2 (de)
AT (1) ATE105085T1 (de)
AU (1) AU578064B2 (de)
CA (1) CA1268209A (de)
DE (1) DE3587804T2 (de)
GB (1) GB8402058D0 (de)
IL (1) IL74161A (de)

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US4927502A (en) * 1989-01-31 1990-05-22 Board Of Regents, The University Of Texas Methods and apparatus using galvanic immunoelectrodes
US5198367A (en) * 1989-06-09 1993-03-30 Masuo Aizawa Homogeneous amperometric immunoassay
GB9009761D0 (en) * 1990-05-01 1990-06-20 Secr Defence Substrate regenerating biosensor
EP0525723B1 (de) * 1991-07-29 1997-05-14 Mochida Pharmaceutical Co., Ltd. Verfahren und Vorrichtung zur Verwendung in spezifischen Bindungstests
US5710011A (en) * 1992-06-05 1998-01-20 Medisense, Inc. Mediators to oxidoreductase enzymes
US5427912A (en) * 1993-08-27 1995-06-27 Boehringer Mannheim Corporation Electrochemical enzymatic complementation immunoassay
US5494831A (en) * 1993-08-30 1996-02-27 Hughes Aircraft Company Electrochemical immunosensor system and methods
US5779867A (en) * 1994-10-07 1998-07-14 Biomedix, Inc. Dry chemistry glucose sensor
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US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
US6207369B1 (en) * 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6361951B1 (en) 1995-06-27 2002-03-26 The University Of North Carolina At Chapel Hill Electrochemical detection of nucleic acid hybridization
US6132971A (en) * 1995-06-27 2000-10-17 The University Of North Carolina At Chapel Hill Microelectronic device
US6294062B1 (en) 1998-06-01 2001-09-25 Roche Diagnostics Corporation Method and device for electrochemical immunoassay of multiple analytes
AU4318599A (en) * 1998-06-08 1999-12-30 Xanthon, Inc. Electrochemical probes for detection of molecular interactions and drug discovery
US6281006B1 (en) 1998-08-24 2001-08-28 Therasense, Inc. Electrochemical affinity assay
US6638716B2 (en) 1998-08-24 2003-10-28 Therasense, Inc. Rapid amperometric verification of PCR amplification of DNA
WO2001038873A2 (en) 1999-11-24 2001-05-31 Biotronic Technologies, Inc. Devices and methods for detecting analytes using electrosensor having capture reagent
US6887714B2 (en) * 2000-10-16 2005-05-03 Board Of Trustees Of The University Of Arkansas, N.A. Microvolume immunoabsorbant assays with amplified electrochemical detection
EP1331482A1 (de) * 2002-01-25 2003-07-30 BMS Sensor Technology SA Konjugat zur Bestimmung von Antigenen mittels Biosensoren
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
US20070056852A1 (en) * 2004-07-23 2007-03-15 Canon Kabushiki Kaisha Enzyme electrode sensor fuel cell and electrochemical reactor
JP2006133137A (ja) * 2004-11-08 2006-05-25 Eiichi Tamiya 被検物質の検出方法
US7534394B1 (en) * 2005-07-11 2009-05-19 The United States Of America As Represented By The Secretary Of The Navy Potentiometric titration method for quantitative determination of hydrogen peroxide
SE531054C2 (sv) 2007-03-01 2008-12-02 Vaederstad Verken Ab Avskrapningsanordning för jordbruksmaskiner och avskrapningsverktyg därtill
AU2008279042B2 (en) * 2007-07-26 2014-03-13 Agamatrix, Inc. Electrochemical analyte detection apparatus and method
US20120046533A1 (en) 2007-08-29 2012-02-23 Medtronic Minimed, Inc. Combined sensor and infusion sets
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
US20110288388A1 (en) 2009-11-20 2011-11-24 Medtronic Minimed, Inc. Multi-conductor lead configurations useful with medical device systems and methods for making and using them
US20110195526A1 (en) * 2010-02-11 2011-08-11 University Of Central Florida Research Foundation Thermo-probes, methods of making thermo-probes, and methods of detection using thermo-probes
US10448872B2 (en) 2010-03-16 2019-10-22 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
US10126296B2 (en) 2010-08-05 2018-11-13 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
WO2012019108A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
EP2601526B1 (de) 2010-08-05 2016-12-21 Abbott Point Of Care, Inc. Magnetischer immunsensor und anwendungsverfahren dafür
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
EP2646152B1 (de) 2010-12-03 2017-04-19 Abbott Point of Care Inc. Probendosierungsvorrichtung und testvorrichtung mit integrierter probenverdünnung
WO2012075258A2 (en) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Ratiometric immunoassay method and blood testing device
WO2012075256A2 (en) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Sample metering device and assay device with integrated sample dilution
US9050595B2 (en) 2010-12-03 2015-06-09 Abbott Point Of Care Inc. Assay devices with integrated sample dilution and dilution verification and methods of using same
KR101226655B1 (ko) * 2011-01-28 2013-01-25 서강대학교산학협력단 전기화학적 방법을 기반으로 한 세포 주기 측정 방법
GB201102037D0 (en) * 2011-02-07 2011-03-23 Multi Sense Technologies Ltd Microfluidics based assay device
US9008744B2 (en) 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
EP2657347A1 (de) 2012-04-26 2013-10-30 Université Paris Diderot - Paris 7 Elektroschemisch wettbewerbsfähiger Assay und Verwendung davon
WO2014059089A1 (en) * 2012-10-10 2014-04-17 Luminescent MD, LLC Chemiluminescent aptasensors
US20150031014A1 (en) * 2013-07-25 2015-01-29 The Board Of Trustees Of The University Of Illinois Detecting analytes with a ph meter
CN106133512A (zh) * 2014-01-27 2016-11-16 株式会社日立高新技术 自动分析装置

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US4321123A (en) * 1978-04-21 1982-03-23 Matsushita Electric Industrial Co., Ltd. Coenzyme immobilized electrode
US4600690A (en) * 1978-08-07 1986-07-15 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Immunoassay
US4340448A (en) * 1978-08-28 1982-07-20 University Of Pittsburgh Potentiometric detection of hydrogen peroxide and apparatus therefor
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DE3278334D1 (en) * 1981-10-23 1988-05-19 Genetics Int Inc Sensor for components of a liquid mixture
CA1219040A (en) * 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
CA1220818A (en) * 1983-05-05 1987-04-21 Hugh A.O. Hill Assay techniques utilising specific binding agents
CA1226036A (en) * 1983-05-05 1987-08-25 Irving J. Higgins Analytical equipment and sensor electrodes therefor
CA1223638A (en) * 1983-05-05 1987-06-30 Graham Davis Assay systems utilising more than one enzyme
CA1218704A (en) * 1983-05-05 1987-03-03 Graham Davis Assay systems using more than one enzyme
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Also Published As

Publication number Publication date
EP0150999B1 (de) 1994-04-27
CA1268209A (en) 1990-04-24
AU3811585A (en) 1985-08-01
AU578064B2 (en) 1988-10-13
ATE105085T1 (de) 1994-05-15
EP0150999A2 (de) 1985-08-07
IL74161A (en) 1989-03-31
IL74161A0 (en) 1985-04-30
US5149630A (en) 1992-09-22
EP0150999A3 (en) 1986-12-30
JPH07107530B2 (ja) 1995-11-15
GB8402058D0 (en) 1984-02-29
DE3587804D1 (de) 1994-06-01
JPS60242361A (ja) 1985-12-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LABORATOIRES SERONO S.A., AUBONNE, CH