DE3685958T2 - Durch ultraschall gesteuerte polymere vorrichtungen zur wirkstoffabgabe. - Google Patents

Durch ultraschall gesteuerte polymere vorrichtungen zur wirkstoffabgabe.

Info

Publication number
DE3685958T2
DE3685958T2 DE8686106725T DE3685958T DE3685958T2 DE 3685958 T2 DE3685958 T2 DE 3685958T2 DE 8686106725 T DE8686106725 T DE 8686106725T DE 3685958 T DE3685958 T DE 3685958T DE 3685958 T2 DE3685958 T2 DE 3685958T2
Authority
DE
Germany
Prior art keywords
active substances
delivering active
controlled polymers
ultrasonically controlled
ultrasonically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686106725T
Other languages
English (en)
Other versions
DE3685958D1 (de
Inventor
Robert S Langer
Joseph Kost
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of DE3685958D1 publication Critical patent/DE3685958D1/de
Publication of DE3685958T2 publication Critical patent/DE3685958T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04—Polyanhydrides
DE8686106725T 1984-07-23 1986-05-16 Durch ultraschall gesteuerte polymere vorrichtungen zur wirkstoffabgabe. Expired - Lifetime DE3685958T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/633,366 US4657543A (en) 1984-07-23 1984-07-23 Ultrasonically modulated polymeric devices for delivering compositions
CA000507996A CA1291064C (en) 1984-07-23 1986-04-30 Ultrasonically modulated polymeric devices for delivering drug compositions
EP86106725A EP0245535B1 (de) 1984-07-23 1986-05-16 Durch Ultraschall gesteuerte polymere Vorrichtungen zur Wirkstoffabgabe

Publications (2)

Publication Number Publication Date
DE3685958D1 DE3685958D1 (de) 1992-08-13
DE3685958T2 true DE3685958T2 (de) 1993-01-14

Family

ID=39628920

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198686106725T Pending DE245535T1 (de) 1984-07-23 1986-05-16 Durch ultraschall gesteuerte polymere vorrichtungen zur wirkstoffabgabe.
DE8686106725T Expired - Lifetime DE3685958T2 (de) 1984-07-23 1986-05-16 Durch ultraschall gesteuerte polymere vorrichtungen zur wirkstoffabgabe.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198686106725T Pending DE245535T1 (de) 1984-07-23 1986-05-16 Durch ultraschall gesteuerte polymere vorrichtungen zur wirkstoffabgabe.

Country Status (4)

Country Link
US (1) US4657543A (de)
EP (1) EP0245535B1 (de)
CA (1) CA1291064C (de)
DE (2) DE245535T1 (de)

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Also Published As

Publication number Publication date
US4657543A (en) 1987-04-14
CA1291064C (en) 1991-10-22
EP0245535B1 (de) 1992-07-08
EP0245535A1 (de) 1987-11-19
DE245535T1 (de) 1989-03-30
DE3685958D1 (de) 1992-08-13

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