DE3686221D1 - Emulsionen zur parenteralen und/oder oralen verabreichung schwer wasserloeslicher ionisierbarer hydrophober arzneistoffe. - Google Patents

Emulsionen zur parenteralen und/oder oralen verabreichung schwer wasserloeslicher ionisierbarer hydrophober arzneistoffe.

Info

Publication number
DE3686221D1
DE3686221D1 DE8686111470T DE3686221T DE3686221D1 DE 3686221 D1 DE3686221 D1 DE 3686221D1 DE 8686111470 T DE8686111470 T DE 8686111470T DE 3686221 T DE3686221 T DE 3686221T DE 3686221 D1 DE3686221 D1 DE 3686221D1
Authority
DE
Germany
Prior art keywords
parenteral
emulsions
oral administration
heavy water
medicinal substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686111470T
Other languages
English (en)
Other versions
DE3686221T2 (de
Inventor
Narendra Raghunathji Desai
Eugene Albert Carpentier
Madurai Ganesan
Edward Charles Shinal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE3686221D1 publication Critical patent/DE3686221D1/de
Publication of DE3686221T2 publication Critical patent/DE3686221T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
DE8686111470T 1985-09-16 1986-08-19 Emulsionen zur parenteralen und/oder oralen verabreichung schwer wasserloeslicher ionisierbarer hydrophober arzneistoffe. Expired - Fee Related DE3686221T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,306 US4784845A (en) 1985-09-16 1985-09-16 Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs

Publications (2)

Publication Number Publication Date
DE3686221D1 true DE3686221D1 (de) 1992-09-03
DE3686221T2 DE3686221T2 (de) 1993-02-25

Family

ID=25107019

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686111470T Expired - Fee Related DE3686221T2 (de) 1985-09-16 1986-08-19 Emulsionen zur parenteralen und/oder oralen verabreichung schwer wasserloeslicher ionisierbarer hydrophober arzneistoffe.

Country Status (18)

Country Link
US (1) US4784845A (de)
EP (1) EP0215313B1 (de)
JP (1) JPS6267018A (de)
KR (1) KR890004684B1 (de)
AR (1) AR242716A1 (de)
AT (1) ATE78683T1 (de)
AU (1) AU591705B2 (de)
CA (1) CA1272447A (de)
DE (1) DE3686221T2 (de)
DK (1) DK165730C (de)
ES (1) ES2002750A6 (de)
FI (1) FI863728A (de)
GR (1) GR862354B (de)
HU (1) HU199282B (de)
NO (1) NO863670L (de)
NZ (1) NZ217484A (de)
PH (1) PH23736A (de)
ZA (1) ZA867009B (de)

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JPH06245700A (ja) * 1993-02-23 1994-09-06 Snow Brand Milk Prod Co Ltd 消化吸収性を低減した油脂組成物
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US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
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US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US6054421A (en) * 1997-09-23 2000-04-25 Scimed Life Systems, Inc. Medical emulsion lubricant
US6281175B1 (en) 1997-09-23 2001-08-28 Scimed Life Systems, Inc. Medical emulsion for lubrication and delivery of drugs
KR100537713B1 (ko) * 1997-09-30 2005-12-20 일라이 릴리 앤드 캄파니 2-메틸-티에노-벤조디아제핀 제제
US6036946A (en) * 1997-12-24 2000-03-14 Shaklee Corporation Methods for protecting skin from damaging effects of ultraviolet light
WO1999043301A1 (en) * 1998-02-24 1999-09-02 The Board Of Trustees Of The University Of Illinois Lipid emulsions in the treatment of systemic poisoning
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US6146664A (en) * 1998-07-10 2000-11-14 Shaklee Corporation Stable topical ascorbic acid compositions
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
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KR20050044655A (ko) * 2001-12-03 2005-05-12 노바세아, 인크. 활성 비타민 ｄ 화합물을 함유하는 약제학적 조성물
WO2003057128A2 (en) * 2001-12-11 2003-07-17 Dor Biopharma, Inc. Lipid particles and suspensions and uses thereof
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040062779A1 (en) * 2002-09-26 2004-04-01 Jerry Whittemore Dermatologic composition using ultra-fine/micronized 1-ascorbic acid and other antioxidant ingredients in a stabilized anhydrous vehicle
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
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WO2006073886A1 (en) 2005-01-05 2006-07-13 Eli Lilly And Company Olanzapine pamoate dihydrate
KR101327649B1 (ko) * 2005-03-31 2013-11-12 산토리 홀딩스 가부시키가이샤 리그난류 화합물 함유 수중 유적형 에멀션 및 그것을함유하는 조성물
JP2009515990A (ja) * 2005-11-17 2009-04-16 バイオアバイラビリティ，インク． 生体適合性潜在的乳化剤
KR101425241B1 (ko) * 2006-10-04 2014-08-01 산토리 홀딩스 가부시키가이샤 리그난류 화합물 함유 ｏ/ｗ/ｏ형 에멀션 및 그것을 함유하는 조성물
EP2200613B1 (de) 2007-09-21 2018-09-05 The Johns Hopkins University Phenazin-derivate und ihre verwendungen
WO2010008891A2 (en) * 2008-06-24 2010-01-21 Merial Limited Anthelminthic formulations
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US20160303242A1 (en) 2013-12-09 2016-10-20 Durect Corporation Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same
WO2019055370A1 (en) * 2017-09-12 2019-03-21 Academic Pharmaceuticals, Inc. METOLAZONE EMULSION FORMULATION
WO2020089942A2 (en) * 2018-11-02 2020-05-07 Amaterasu Lifesciences Llp A liquid injectable composition

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Also Published As

Publication number Publication date
ZA867009B (en) 1987-07-29
CA1272447A (en) 1990-08-07
US4784845A (en) 1988-11-15
KR890004684B1 (ko) 1989-11-25
GR862354B (en) 1987-01-19
FI863728A0 (fi) 1986-09-15
DK438286A (da) 1987-03-17
HUT43947A (en) 1988-01-28
EP0215313A3 (en) 1987-09-09
DE3686221T2 (de) 1993-02-25
NO863670D0 (no) 1986-09-15
HU199282B (en) 1990-02-28
EP0215313B1 (de) 1992-07-29
NZ217484A (en) 1990-04-26
AU6269686A (en) 1987-03-19
ES2002750A6 (es) 1988-10-01
PH23736A (en) 1989-11-03
JPS6267018A (ja) 1987-03-26
DK165730B (da) 1993-01-11
DK438286D0 (da) 1986-09-12
NO863670L (no) 1987-03-17
EP0215313A2 (de) 1987-03-25
ATE78683T1 (de) 1992-08-15
DK165730C (da) 1993-06-07
FI863728A (fi) 1987-03-17
KR870002835A (ko) 1987-04-13
AR242716A1 (es) 1993-05-31
AU591705B2 (en) 1989-12-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee