DE3770830D1 - Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. - Google Patents
Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion.Info
- Publication number
- DE3770830D1 DE3770830D1 DE8787850029T DE3770830T DE3770830D1 DE 3770830 D1 DE3770830 D1 DE 3770830D1 DE 8787850029 T DE8787850029 T DE 8787850029T DE 3770830 T DE3770830 T DE 3770830T DE 3770830 D1 DE3770830 D1 DE 3770830D1
- Authority
- DE
- Germany
- Prior art keywords
- water emulsion
- pregnanolol
- preparation
- stable oil
- pregnanolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600632A SE8600632D0 (sv) | 1986-02-13 | 1986-02-13 | Novel pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3770830D1 true DE3770830D1 (de) | 1991-07-25 |
Family
ID=20363448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787850029T Expired - Fee Related DE3770830D1 (de) | 1986-02-13 | 1987-01-29 | Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5028600A (de) |
EP (1) | EP0233849B1 (de) |
JP (1) | JPH0788305B2 (de) |
AT (1) | ATE64526T1 (de) |
CA (1) | CA1301651C (de) |
DE (1) | DE3770830D1 (de) |
DK (1) | DK175504B1 (de) |
ES (1) | ES2037742T3 (de) |
FI (1) | FI88676C (de) |
GR (1) | GR3002299T3 (de) |
HK (1) | HK83293A (de) |
NO (1) | NO175040B (de) |
SE (1) | SE8600632D0 (de) |
SG (1) | SG102892G (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9302295D0 (sv) * | 1993-07-02 | 1993-07-02 | Kabi Pharmacia Ab | New pharmaceutical composition |
US5616330A (en) * | 1994-07-19 | 1997-04-01 | Hemagen/Pfc | Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same |
US6117429A (en) * | 1997-08-11 | 2000-09-12 | Weider Nutrition International, Inc | Compositions and treatments for reducing potential unwanted side effects associated with long-term administration of androgenic testosterone precursors |
US20020155161A1 (en) * | 2000-12-29 | 2002-10-24 | Deckelbaum Richard J. | Use of IV emulsions with different triglyceride composition, particle size and apolipoprotein E for targeted tissue delivery of hydrophobic compounds |
JP4559221B2 (ja) * | 2002-07-02 | 2010-10-06 | ニコメド ゲゼルシャフト ミット ベシュレンクテル ハフツング | シクレソニド含有無菌水性懸濁製剤 |
PE20050941A1 (es) | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
EP1799266A2 (de) * | 2004-09-13 | 2007-06-27 | Bharat Serums & Vaccines Ltd. | Stabile emulsionszusammensetzungen für die intravenöse verabreichung mit antimikrobiell erhaltender wirksamkeit |
EP2663326B2 (de) * | 2011-01-14 | 2021-09-29 | Vivacelle Bio, Inc. | Verfahren und zusammensetzungen zur behandlung von leiden in zusammenhang mit mangelnder blutversorgung, schocks und verletzungen |
US10478505B2 (en) | 2011-09-23 | 2019-11-19 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
SG10201606063RA (en) | 2012-01-23 | 2016-09-29 | Sage Therapeutics Inc | Neuroactive steroid formulations and methods of treating cns disorders |
US20140050789A1 (en) | 2012-08-13 | 2014-02-20 | The Regents Of The University Of California | Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids |
EP4335505A2 (de) | 2012-11-30 | 2024-03-13 | The Regents of The University of California | Antikonvulsive aktivität von steroiden |
RU2022102537A (ru) | 2016-03-08 | 2022-03-30 | Сейдж Терапьютикс, Инк. | Нейроактивные стероиды, их композиции и применения |
CN113613632A (zh) * | 2018-12-10 | 2021-11-05 | 光环科学有限责任公司 | 麻醉剂的稳定制剂和相关剂型 |
EP4017498A4 (de) * | 2019-08-19 | 2022-11-09 | Arizona Board of Regents on behalf of the University of Arizona | Topische neurosteroidformulierungen |
CN114344309B (zh) * | 2021-12-30 | 2024-02-06 | 南京迈诺威医药科技有限公司 | 一种别孕烷醇酮衍生物自乳化制剂及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1215702B (de) * | 1962-07-03 | 1966-05-05 | Merck Ag E | Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen |
CA895860A (en) * | 1969-11-05 | 1972-03-21 | Kruger Gunther | PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE |
US3900561A (en) * | 1970-12-17 | 1975-08-19 | Glaxo Lab Ltd | Pharmaceutical compositions |
US3917830A (en) * | 1970-12-17 | 1975-11-04 | Glaxo Lab Ltd | Steroidal anaesthetic composition for intraveneous injection |
US4168308A (en) * | 1976-03-12 | 1979-09-18 | Apoteksvarucentralen Vitrum Ab | Composition for enhancing the administration of pharmacologically active agents |
JPS609726B2 (ja) * | 1980-05-15 | 1985-03-12 | 株式会社 ミドリ十字 | ステロイド製剤 |
JPS5716818A (en) * | 1981-04-25 | 1982-01-28 | Green Cross Corp:The | Steroid fatty emulsion |
JPS60258110A (ja) * | 1984-06-05 | 1985-12-20 | Daigo Eiyou Kagaku Kk | 静脈注射可能なプロゲステロン乳化注射液 |
-
1986
- 1986-02-13 SE SE8600632A patent/SE8600632D0/xx unknown
-
1987
- 1987-01-29 EP EP87850029A patent/EP0233849B1/de not_active Expired - Lifetime
- 1987-01-29 ES ES198787850029T patent/ES2037742T3/es not_active Expired - Lifetime
- 1987-01-29 DE DE8787850029T patent/DE3770830D1/de not_active Expired - Fee Related
- 1987-01-29 AT AT87850029T patent/ATE64526T1/de not_active IP Right Cessation
- 1987-02-06 DK DK198700621A patent/DK175504B1/da not_active IP Right Cessation
- 1987-02-12 CA CA000529609A patent/CA1301651C/en not_active Expired - Fee Related
- 1987-02-12 NO NO870560A patent/NO175040B/no not_active IP Right Cessation
- 1987-02-12 FI FI870589A patent/FI88676C/fi not_active IP Right Cessation
- 1987-02-12 JP JP62028395A patent/JPH0788305B2/ja not_active Expired - Fee Related
-
1989
- 1989-02-28 US US07/316,576 patent/US5028600A/en not_active Expired - Lifetime
-
1991
- 1991-07-11 GR GR91400996T patent/GR3002299T3/el unknown
-
1992
- 1992-10-07 SG SG1028/92A patent/SG102892G/en unknown
-
1993
- 1993-08-12 HK HK832/93A patent/HK83293A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK62187D0 (da) | 1987-02-06 |
CA1301651C (en) | 1992-05-26 |
JPH0788305B2 (ja) | 1995-09-27 |
GR3002299T3 (en) | 1992-12-30 |
FI88676B (fi) | 1993-03-15 |
DK175504B1 (da) | 2004-11-15 |
NO175040B (no) | 1994-05-16 |
FI870589A (fi) | 1987-08-14 |
ES2037742T3 (es) | 1993-07-01 |
FI870589A0 (fi) | 1987-02-12 |
NO870560D0 (no) | 1987-02-12 |
JPS62192322A (ja) | 1987-08-22 |
EP0233849B1 (de) | 1991-06-19 |
EP0233849A1 (de) | 1987-08-26 |
HK83293A (en) | 1993-08-20 |
SE8600632D0 (sv) | 1986-02-13 |
US5028600A (en) | 1991-07-02 |
NO870560L (no) | 1987-08-14 |
DK62187A (da) | 1987-08-14 |
SG102892G (en) | 1992-12-04 |
FI88676C (fi) | 1993-06-28 |
ATE64526T1 (de) | 1991-07-15 |
NO175040C (de) | 1994-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |