DE3770830D1 - Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. - Google Patents

Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion.

Info

Publication number
DE3770830D1
DE3770830D1 DE8787850029T DE3770830T DE3770830D1 DE 3770830 D1 DE3770830 D1 DE 3770830D1 DE 8787850029 T DE8787850029 T DE 8787850029T DE 3770830 T DE3770830 T DE 3770830T DE 3770830 D1 DE3770830 D1 DE 3770830D1
Authority
DE
Germany
Prior art keywords
water emulsion
pregnanolol
preparation
stable oil
pregnanolone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787850029T
Other languages
English (en)
Inventor
Roland Ingolf Jeppsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Kabi Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia AB filed Critical Kabi Pharmacia AB
Application granted granted Critical
Publication of DE3770830D1 publication Critical patent/DE3770830D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
DE8787850029T 1986-02-13 1987-01-29 Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. Expired - Fee Related DE3770830D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8600632A SE8600632D0 (sv) 1986-02-13 1986-02-13 Novel pharmaceutical composition

Publications (1)

Publication Number Publication Date
DE3770830D1 true DE3770830D1 (de) 1991-07-25

Family

ID=20363448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787850029T Expired - Fee Related DE3770830D1 (de) 1986-02-13 1987-01-29 Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion.

Country Status (14)

Country Link
US (1) US5028600A (de)
EP (1) EP0233849B1 (de)
JP (1) JPH0788305B2 (de)
AT (1) ATE64526T1 (de)
CA (1) CA1301651C (de)
DE (1) DE3770830D1 (de)
DK (1) DK175504B1 (de)
ES (1) ES2037742T3 (de)
FI (1) FI88676C (de)
GR (1) GR3002299T3 (de)
HK (1) HK83293A (de)
NO (1) NO175040B (de)
SE (1) SE8600632D0 (de)
SG (1) SG102892G (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302295D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab New pharmaceutical composition
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US6117429A (en) * 1997-08-11 2000-09-12 Weider Nutrition International, Inc Compositions and treatments for reducing potential unwanted side effects associated with long-term administration of androgenic testosterone precursors
US20020155161A1 (en) * 2000-12-29 2002-10-24 Deckelbaum Richard J. Use of IV emulsions with different triglyceride composition, particle size and apolipoprotein E for targeted tissue delivery of hydrophobic compounds
JP4559221B2 (ja) * 2002-07-02 2010-10-06 ニコメド ゲゼルシャフト ミット ベシュレンクテル ハフツング シクレソニド含有無菌水性懸濁製剤
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
EP1799266A2 (de) * 2004-09-13 2007-06-27 Bharat Serums & Vaccines Ltd. Stabile emulsionszusammensetzungen für die intravenöse verabreichung mit antimikrobiell erhaltender wirksamkeit
EP2663326B2 (de) * 2011-01-14 2021-09-29 Vivacelle Bio, Inc. Verfahren und zusammensetzungen zur behandlung von leiden in zusammenhang mit mangelnder blutversorgung, schocks und verletzungen
US10478505B2 (en) 2011-09-23 2019-11-19 The Regents Of The University Of California Edible oils to enhance delivery of orally administered steroids
SG10201606063RA (en) 2012-01-23 2016-09-29 Sage Therapeutics Inc Neuroactive steroid formulations and methods of treating cns disorders
US20140050789A1 (en) 2012-08-13 2014-02-20 The Regents Of The University Of California Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
EP4335505A2 (de) 2012-11-30 2024-03-13 The Regents of The University of California Antikonvulsive aktivität von steroiden
RU2022102537A (ru) 2016-03-08 2022-03-30 Сейдж Терапьютикс, Инк. Нейроактивные стероиды, их композиции и применения
CN113613632A (zh) * 2018-12-10 2021-11-05 光环科学有限责任公司 麻醉剂的稳定制剂和相关剂型
EP4017498A4 (de) * 2019-08-19 2022-11-09 Arizona Board of Regents on behalf of the University of Arizona Topische neurosteroidformulierungen
CN114344309B (zh) * 2021-12-30 2024-02-06 南京迈诺威医药科技有限公司 一种别孕烷醇酮衍生物自乳化制剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1215702B (de) * 1962-07-03 1966-05-05 Merck Ag E Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen
CA895860A (en) * 1969-11-05 1972-03-21 Kruger Gunther PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) * 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液

Also Published As

Publication number Publication date
DK62187D0 (da) 1987-02-06
CA1301651C (en) 1992-05-26
JPH0788305B2 (ja) 1995-09-27
GR3002299T3 (en) 1992-12-30
FI88676B (fi) 1993-03-15
DK175504B1 (da) 2004-11-15
NO175040B (no) 1994-05-16
FI870589A (fi) 1987-08-14
ES2037742T3 (es) 1993-07-01
FI870589A0 (fi) 1987-02-12
NO870560D0 (no) 1987-02-12
JPS62192322A (ja) 1987-08-22
EP0233849B1 (de) 1991-06-19
EP0233849A1 (de) 1987-08-26
HK83293A (en) 1993-08-20
SE8600632D0 (sv) 1986-02-13
US5028600A (en) 1991-07-02
NO870560L (no) 1987-08-14
DK62187A (da) 1987-08-14
SG102892G (en) 1992-12-04
FI88676C (fi) 1993-06-28
ATE64526T1 (de) 1991-07-15
NO175040C (de) 1994-08-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee