DE3779578T2 - Vorrichtung und verfahren zum massentransfer von biologisch-pharmazeutischen medien. - Google Patents

Vorrichtung und verfahren zum massentransfer von biologisch-pharmazeutischen medien.

Info

Publication number
DE3779578T2
DE3779578T2 DE8787310442T DE3779578T DE3779578T2 DE 3779578 T2 DE3779578 T2 DE 3779578T2 DE 8787310442 T DE8787310442 T DE 8787310442T DE 3779578 T DE3779578 T DE 3779578T DE 3779578 T2 DE3779578 T2 DE 3779578T2
Authority
DE
Germany
Prior art keywords
mass transfer
bioreactor
biological
pharmaceutical media
cell growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787310442T
Other languages
English (en)
Other versions
DE3779578D1 (de
Inventor
Henry B Kopf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25468714&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3779578(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of DE3779578D1 publication Critical patent/DE3779578D1/de
Application granted granted Critical
Publication of DE3779578T2 publication Critical patent/DE3779578T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/08—Prevention of membrane fouling or of concentration polarisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/32—Controlling or regulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/082—Flat membrane modules comprising a stack of flat membranes
    • B01D63/084—Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/12—Pulsatile flow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/16—Use of chemical agents
    • B01D2321/168—Use of other chemical agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/20—By influencing the flow
    • B01D2321/2066—Pulsated flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/20—By influencing the flow
    • B01D2321/2083—By reversing the flow
DE8787310442T 1986-11-26 1987-11-26 Vorrichtung und verfahren zum massentransfer von biologisch-pharmazeutischen medien. Expired - Lifetime DE3779578T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/936,486 US4885087A (en) 1986-11-26 1986-11-26 Apparatus for mass transfer involving biological/pharmaceutical media

Publications (2)

Publication Number Publication Date
DE3779578D1 DE3779578D1 (de) 1992-07-09
DE3779578T2 true DE3779578T2 (de) 1992-12-24

Family

ID=25468714

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787310442T Expired - Lifetime DE3779578T2 (de) 1986-11-26 1987-11-26 Vorrichtung und verfahren zum massentransfer von biologisch-pharmazeutischen medien.

Country Status (5)

Country Link
US (2) US4885087A (de)
EP (1) EP0269444B1 (de)
JP (1) JPS63151306A (de)
AT (1) ATE76897T1 (de)
DE (1) DE3779578T2 (de)

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Also Published As

Publication number Publication date
EP0269444A3 (en) 1989-07-19
US4885087A (en) 1989-12-05
DE3779578D1 (de) 1992-07-09
JPS63151306A (ja) 1988-06-23
EP0269444B1 (de) 1992-06-03
ATE76897T1 (de) 1992-06-15
US6048727A (en) 2000-04-11
EP0269444A2 (de) 1988-06-01

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