DE3784576D1 - Optische polymerbedeckte strukturen. - Google Patents

Optische polymerbedeckte strukturen.

Info

Publication number
DE3784576D1
DE3784576D1 DE8787306535T DE3784576T DE3784576D1 DE 3784576 D1 DE3784576 D1 DE 3784576D1 DE 8787306535 T DE8787306535 T DE 8787306535T DE 3784576 T DE3784576 T DE 3784576T DE 3784576 D1 DE3784576 D1 DE 3784576D1
Authority
DE
Germany
Prior art keywords
optical polymer
polymer covered
covered structures
ligand
optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787306535T
Other languages
English (en)
Other versions
DE3784576T2 (de
Inventor
Robin Edward Godfrey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Application granted granted Critical
Publication of DE3784576D1 publication Critical patent/DE3784576D1/de
Publication of DE3784576T2 publication Critical patent/DE3784576T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
DE8787306535T 1986-07-24 1987-07-23 Optische polymerbedeckte strukturen. Expired - Lifetime DE3784576T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868618133A GB8618133D0 (en) 1986-07-24 1986-07-24 Biosensors

Publications (2)

Publication Number Publication Date
DE3784576D1 true DE3784576D1 (de) 1993-04-15
DE3784576T2 DE3784576T2 (de) 1993-09-23

Family

ID=10601651

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787306535T Expired - Lifetime DE3784576T2 (de) 1986-07-24 1987-07-23 Optische polymerbedeckte strukturen.

Country Status (10)

Country Link
US (1) US4992385A (de)
EP (1) EP0254575B1 (de)
JP (2) JP2528134B2 (de)
AT (1) ATE86744T1 (de)
CA (1) CA1303981C (de)
DE (1) DE3784576T2 (de)
ES (1) ES2038183T3 (de)
GB (1) GB8618133D0 (de)
GR (1) GR3007383T3 (de)
IL (1) IL83180A (de)

Families Citing this family (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8705650D0 (en) * 1987-03-10 1987-04-15 Pa Consulting Services Assay technique
GB8705649D0 (en) * 1987-03-10 1987-04-15 Pa Consulting Services Assay sensor
GB8804669D0 (en) * 1988-02-27 1988-03-30 Medical Res Council Immobilisation of haptens
GB2217447A (en) * 1988-04-21 1989-10-25 Atomic Energy Authority Uk Bonding to metal surfaces
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
AU6354190A (en) * 1989-08-21 1991-04-03 Board Of Regents Of The University Of Washington, The Multiple-probe diagnostic sensor
JPH03122553A (ja) * 1989-10-04 1991-05-24 Olympus Optical Co Ltd 光センサー
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
JPH05504195A (ja) * 1990-02-22 1993-07-01 ザ・ロイヤル・インステイチユーシヨン・フオー・ジ・アドバンスメント・オブ・ラーニング　（マクギル・ユニバーシテイ） 固相干渉イムノアッセイ系
JPH04211202A (ja) * 1990-03-19 1992-08-03 Canon Inc 反射型回折格子および該回折格子を用いた装置
DE4024476C1 (de) * 1990-08-02 1992-02-27 Boehringer Mannheim Gmbh, 6800 Mannheim, De
US5763191A (en) * 1990-12-12 1998-06-09 Boehringer Mannheim Gmbh Universal binding film
DE4039677A1 (de) * 1990-12-12 1992-06-17 Boehringer Mannheim Gmbh Universalbindefilm
JPH05506314A (ja) * 1991-02-11 1993-09-16 バイオスター・メディカル・プロダクツ・インコーポレイテッド 生物学的結合の光学的検出に使用する試験表面の製造方法
EP0643833A1 (de) * 1991-06-04 1995-03-22 FISONS plc Analysevorrichtung
GB9111912D0 (en) * 1991-06-04 1991-07-24 Fisons Plc Analytical methods
JPH07500413A (ja) * 1991-07-22 1995-01-12 クロエン、インストルメンツ、リミテッド 表面向上分析処理用基質及び特定の目的のために準備された基質
US5837552A (en) * 1991-07-22 1998-11-17 Medifor, Ltd. Surface-enhanced analytical procedures and substrates
CA2139242A1 (en) * 1992-07-17 1994-02-03 Richard Calvin Ebersole Analyte detection by means of an analyte-responsive polymer
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
EP0598340B1 (de) * 1992-11-17 2012-06-13 O.S.P. Inc. Verwendung eines Copolymerfilms auf einem Substrat zur Detektion chemischer Substanzen
GB2273772A (en) * 1992-12-16 1994-06-29 Granta Lab Ltd Detection of macromolecules utilising light diffraction
US5395587A (en) * 1993-07-06 1995-03-07 Smithkline Beecham Corporation Surface plasmon resonance detector having collector for eluted ligate
US5955153A (en) * 1993-10-01 1999-09-21 Johnson & Johnson Clinical Diagnostics, Inc. Production of carriers for surface plasmon resonance
ATE208653T1 (de) * 1994-03-04 2001-11-15 Usf Filtration & Separations Gross-porige membran aus synthetischen polymeren
GB9406142D0 (en) 1994-03-28 1994-05-18 British Tech Group A sensor
US5854863A (en) * 1996-03-15 1998-12-29 Erb; Judith Surface treatment and light injection method and apparatus
US5852229A (en) * 1996-05-29 1998-12-22 Kimberly-Clark Worldwide, Inc. Piezoelectric resonator chemical sensing device
US6020047A (en) * 1996-09-04 2000-02-01 Kimberly-Clark Worldwide, Inc. Polymer films having a printed self-assembling monolayer
US6048623A (en) * 1996-12-18 2000-04-11 Kimberly-Clark Worldwide, Inc. Method of contact printing on gold coated films
US5922550A (en) * 1996-12-18 1999-07-13 Kimberly-Clark Worldwide, Inc. Biosensing devices which produce diffraction images
US5958704A (en) * 1997-03-12 1999-09-28 Ddx, Inc. Sensing system for specific substance and molecule detection
US6180288B1 (en) 1997-03-21 2001-01-30 Kimberly-Clark Worldwide, Inc. Gel sensors and method of use thereof
US5955378A (en) * 1997-08-20 1999-09-21 Challener; William A. Near normal incidence optical assaying method and system having wavelength and angle sensitivity
US5925878A (en) * 1997-08-20 1999-07-20 Imation Corp. Diffraction anomaly sensor having grating coated with protective dielectric layer
US5994150A (en) * 1997-11-19 1999-11-30 Imation Corp. Optical assaying method and system having rotatable sensor disk with multiple sensing regions
JP3437170B2 (ja) * 1997-12-12 2003-08-18 ピーイー コーポレイション （エヌワイ） 光学共鳴解析システム
US6060256A (en) 1997-12-16 2000-05-09 Kimberly-Clark Worldwide, Inc. Optical diffraction biosensor
US5986762A (en) * 1998-06-15 1999-11-16 Imation Corp. Optical sensor having optimized surface profile
GB9820919D0 (en) * 1998-09-26 1998-11-18 Secr Defence Diagnostic method
US6320991B1 (en) 1998-10-16 2001-11-20 Imation Corp. Optical sensor having dielectric film stack
US6221579B1 (en) * 1998-12-11 2001-04-24 Kimberly-Clark Worldwide, Inc. Patterned binding of functionalized microspheres for optical diffraction-based biosensors
US6579673B2 (en) * 1998-12-17 2003-06-17 Kimberly-Clark Worldwide, Inc. Patterned deposition of antibody binding protein for optical diffraction-based biosensors
US6771376B2 (en) * 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
EP1192448B1 (de) 1999-07-05 2006-09-27 Novartis AG Verfahren zur anwendung einer sensoreinheit
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US8111401B2 (en) * 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US6399295B1 (en) 1999-12-17 2002-06-04 Kimberly-Clark Worldwide, Inc. Use of wicking agent to eliminate wash steps for optical diffraction-based biosensors
EP1266207B1 (de) * 2000-03-22 2010-10-27 Axela Inc. Verfahren und vorrichtung zur bestimmung mehrerer analyten
US7264973B2 (en) * 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US20030092075A1 (en) * 2000-10-30 2003-05-15 Sru Biosystems, Llc Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors
US7306827B2 (en) * 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7142296B2 (en) * 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US20030113766A1 (en) * 2000-10-30 2003-06-19 Sru Biosystems, Llc Amine activated colorimetric resonant biosensor
US7153702B2 (en) * 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7371562B2 (en) * 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7094595B2 (en) * 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7175980B2 (en) * 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7202076B2 (en) 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7217574B2 (en) * 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7101660B2 (en) * 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7023544B2 (en) 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7615339B2 (en) * 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7070987B2 (en) * 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7300803B2 (en) * 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7875434B2 (en) * 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US6576430B1 (en) * 2000-11-20 2003-06-10 Becton, Dickinson And Company Detection of ligands by refractive surface methods
DE10064146A1 (de) * 2000-12-22 2002-07-04 Andreas Hofmann Biosensor und verfahren zu seiner Herstellung
JP4554205B2 (ja) * 2001-09-13 2010-09-29 アクセラ インコーポレーテッド 光の回折に基づく検定のための方法および装置
US7098041B2 (en) 2001-12-11 2006-08-29 Kimberly-Clark Worldwide, Inc. Methods to view and analyze the results from diffraction-based diagnostics
US7102752B2 (en) 2001-12-11 2006-09-05 Kimberly-Clark Worldwide, Inc. Systems to view and analyze the results from diffraction-based diagnostics
US7384598B2 (en) * 2001-12-21 2008-06-10 Kimberly-Clark Worldwide, Inc. Diagnostic device
US7244393B2 (en) * 2001-12-21 2007-07-17 Kimberly-Clark Worldwide, Inc. Diagnostic device and system
US20030119203A1 (en) * 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US8367013B2 (en) * 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US7485453B2 (en) * 2002-05-03 2009-02-03 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7223368B2 (en) * 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7214530B2 (en) * 2002-05-03 2007-05-08 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
US7771922B2 (en) * 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device
US7223534B2 (en) * 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7118855B2 (en) * 2002-05-03 2006-10-10 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
DE10222979B4 (de) * 2002-05-23 2006-06-08 Sartorius Ag Verfahren zur Verstärkung eines Signals
US7091049B2 (en) * 2002-06-26 2006-08-15 Kimberly-Clark Worldwide, Inc. Enhanced diffraction-based biosensor devices
US20040126875A1 (en) * 2002-09-12 2004-07-01 Putnam Martin A. Assay stick
US7126755B2 (en) * 2002-09-12 2006-10-24 Moon John A Method and apparatus for labeling using diffraction grating-based encoded optical identification elements
EP1535241A1 (de) * 2002-08-20 2005-06-01 Cyvera Corporation Auf einem beugungsgitter basierendes optisches identifikationselement
US7872804B2 (en) * 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7900836B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7164533B2 (en) * 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7190522B2 (en) * 2002-09-12 2007-03-13 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
US7901630B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7441703B2 (en) * 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7508608B2 (en) * 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
EP1535242A1 (de) * 2002-08-20 2005-06-01 Cyvera Corporation Auf der basis eines beugungsgitters codierte mikropartikel für gemultiplexte experimente
US20050227252A1 (en) * 2002-08-20 2005-10-13 Moon John A Diffraction grating-based encoded articles for multiplexed experiments
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7285424B2 (en) * 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7314763B2 (en) * 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US20040043508A1 (en) * 2002-09-03 2004-03-04 Frutos Anthony G. Polymer-coated substrates for binding biological molecules
US7927822B2 (en) * 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7429492B2 (en) * 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
WO2004024328A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
WO2004025563A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
US7169550B2 (en) * 2002-09-26 2007-01-30 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7781172B2 (en) * 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US20040106190A1 (en) * 2002-12-03 2004-06-03 Kimberly-Clark Worldwide, Inc. Flow-through assay devices
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
US20040121334A1 (en) * 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7851209B2 (en) * 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) * 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7070406B2 (en) * 2003-04-29 2006-07-04 Hewlett-Packard Development Company, L.P. Apparatus for embossing a flexible substrate with a pattern carried by an optically transparent compliant media
US7497992B2 (en) * 2003-05-08 2009-03-03 Sru Biosystems, Inc. Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers
US20060057729A1 (en) * 2003-09-12 2006-03-16 Illumina, Inc. Diffraction grating-based encoded element having a substance disposed thereon
US8298780B2 (en) * 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
AU2004290375A1 (en) * 2003-11-06 2005-05-26 Sru Biosystems, Inc. High-density amine-functionalized surface
US7943395B2 (en) * 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050112703A1 (en) * 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) * 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US20050136550A1 (en) * 2003-12-19 2005-06-23 Kimberly-Clark Worldwide, Inc. Flow control of electrochemical-based assay devices
US7943089B2 (en) * 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7433123B2 (en) * 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US7796266B2 (en) * 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7815854B2 (en) * 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
US20050244953A1 (en) * 2004-04-30 2005-11-03 Kimberly-Clark Worldwide, Inc. Techniques for controlling the optical properties of assay devices
US7521226B2 (en) * 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
WO2006020363A2 (en) * 2004-07-21 2006-02-23 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
WO2006055736A1 (en) 2004-11-16 2006-05-26 Illumina, Inc. And methods and apparatus for reading coded microbeads
WO2006055735A2 (en) 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
US7604173B2 (en) * 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
US20060110594A1 (en) * 2004-11-24 2006-05-25 Frutos Anthony G Polymer-coated substrates for binding biomolecules and methods of making and using thereof
US20070121113A1 (en) * 2004-12-22 2007-05-31 Cohen David S Transmission-based optical detection systems
US20060141527A1 (en) * 2004-12-29 2006-06-29 Caracci Stephen J Method for creating a reference region and a sample region on a biosensor and the resulting biosensor
US7604984B2 (en) * 2004-12-29 2009-10-20 Corning Incorporated Spatially scanned optical reader system and method for using same
US7629173B2 (en) * 2004-12-29 2009-12-08 Corning Incorporated Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors
US7623624B2 (en) * 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
US7781203B2 (en) * 2005-12-29 2010-08-24 Corning Incorporated Supports for assaying analytes and methods of making and using thereof
US7830575B2 (en) * 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US20070264155A1 (en) * 2006-05-09 2007-11-15 Brady Michael D Aerosol jet deposition method and system for creating a reference region/sample region on a biosensor
AU2007313830A1 (en) * 2006-10-31 2008-05-08 Sru Biosystems, Inc. Method for blocking non-specific protein binding on a functionalized surface
CN101743465A (zh) * 2007-04-19 2010-06-16 Sru生物系统公司 应用生物传感器检测与固定化靶标分子直接结合的小分子的方法
WO2009009718A1 (en) * 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels
US9134307B2 (en) * 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
US7923241B2 (en) * 2007-10-10 2011-04-12 Corning Incorporated Cell culture article and methods thereof
US20100021954A1 (en) * 2008-07-23 2010-01-28 Sophie Deshayes High capacity nanoparticulate immobilization surface
WO2009058214A1 (en) * 2007-10-30 2009-05-07 Corning Incorporated High capacity nanoparticulate immobilization surface
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
EP2304500A1 (de) * 2008-06-04 2011-04-06 SRU Biosystems, Inc. Detektion von promiskuitiven kleinen submikrometeraggregaten
US20100273185A1 (en) * 2009-04-27 2010-10-28 Sru Biosystems, Inc. Detection of Biased Agonist Activation
AU2010248784A1 (en) * 2009-05-15 2011-12-01 Sru Biosystems, Inc Detection of changes in cell populations and mixed cell populations
US8593630B2 (en) * 2009-10-07 2013-11-26 The Board Of Trustees Of The University Of Illinois Discrete frequency spectroscopy and instrumentation
WO2011120042A1 (en) * 2010-03-26 2011-09-29 Sru Biosystems, Inc. Use of induced pluripotent cells and other cells for screening compound libraries

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL67090C (de) * 1947-06-27
DE1108461B (de) * 1954-10-14 1961-06-08 Nat Res Dev Verfahren zum Kopieren von optischen Beugungsgitternachbildungen
US3839067A (en) * 1972-09-25 1974-10-01 Bell Telephone Labor Inc Method of making a thin film wave guide employing stress induced birefringence by desposition in a polymer from solution
US3926564A (en) * 1974-02-25 1975-12-16 Gen Electric Substrate for immunological tests and method of fabrication thereof
US3979184A (en) * 1975-05-27 1976-09-07 General Electric Company Diagnostic device for visually detecting presence of biological particles
US4080476A (en) * 1976-11-15 1978-03-21 Datascope Corporation Anti-fog coated optical substrates
US4357142A (en) * 1980-07-18 1982-11-02 Akzona Incorporated Glass support coated with synthetic polymer for bioprocess
US4363634A (en) * 1980-07-18 1982-12-14 Akzona Incorporated Glass support coated with synthetic polymer for bioprocess
JPS5767860A (en) * 1980-10-15 1982-04-24 Fuji Photo Film Co Ltd Material for multilayer analysis
JPS5821213A (ja) * 1981-07-31 1983-02-08 Canon Inc 光結合装置
DE3135196A1 (de) * 1981-09-05 1983-03-17 Merck Patent Gmbh, 6100 Darmstadt Verfahren, mittel und vorrichtung zur bestimmung biologischer komponenten
DE3343636A1 (de) * 1982-12-07 1984-06-07 AVL AG, 8201 Schaffhausen Sensorelement fuer fluoreszenzoptische messung sowie verfahren zu seiner herstellung
CA1237645A (en) * 1982-12-21 1988-06-07 John H. Fisher Assay technique
US4537861A (en) * 1983-02-03 1985-08-27 Elings Virgil B Apparatus and method for homogeneous immunoassay
DE3346795A1 (de) * 1983-12-23 1985-07-04 E. Prof. Dr. 3550 Marburg Geyer Enzymimmunoassay und entsprechendes diagnostikum
JPS60173842A (ja) * 1984-02-20 1985-09-07 Canon Inc パタ−ン形成方法
GB8413262D0 (en) * 1984-05-24 1984-06-27 Perkins P G Lens coating material
US4647544A (en) * 1984-06-25 1987-03-03 Nicoli David F Immunoassay using optical interference detection
EP0190123A1 (de) * 1984-07-20 1986-08-13 GAUNTT, Charles, O. Immunoregulierende und antivirale verbindung
GB8423204D0 (en) * 1984-09-14 1984-10-17 Comtech Res Unit Assay technique and equipment
GB8509492D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optical assay
DE3680999D1 (de) * 1985-05-29 1991-09-26 Artificial Sensing Instr Asi A Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahlaenderungen in messubstanzen.

Also Published As

Publication number Publication date
JPS63100355A (ja) 1988-05-02
EP0254575B1 (de) 1993-03-10
AU594176B2 (en) 1990-03-01
JP2592588B2 (ja) 1997-03-19
ATE86744T1 (de) 1993-03-15
US4992385A (en) 1991-02-12
JP2528134B2 (ja) 1996-08-28
DE3784576T2 (de) 1993-09-23
EP0254575A2 (de) 1988-01-27
IL83180A (en) 1992-09-06
CA1303981C (en) 1992-06-23
EP0254575A3 (en) 1990-05-30
GB8618133D0 (en) 1986-09-03
GR3007383T3 (de) 1993-07-30
AU7600787A (en) 1988-01-28
JPH0868749A (ja) 1996-03-12
IL83180A0 (en) 1987-12-31
ES2038183T3 (es) 1993-07-16

Similar Documents

Publication Publication Date Title
DE3784576D1 (de) Optische polymerbedeckte strukturen.
NO884984D0 (no) Polymer-belagte optiske strukturer.
DE69004049D1 (de) Vorrichtung für chemische testverfahren.
DE68905610T2 (de) Verfahren zur Herstellung von Reflexionshologrammen in photopolymerisierbaren Schichten.
DE69428000T2 (de) Analysen- und trennungsverfahren
DE3852117T2 (de) Immunoassay mit Verwendung von nichtmetallischen, kolloidalen Teilchen.
DE69302273T2 (de) Verfahren zur verbesserung der messgenauigkeit in messverfahren, die evanescent-wave-biosensoren verwenden
BR7905144A (pt) Correia de transmissao de forca,elemento de reforco e aperfeicoamento em processo para a producao de uma correia de transmissao de forca com blocos em v
DE68913392T2 (de) Vorrichtung zur Entnahme von Kernproben.
BR7902664A (pt) Processo para fundicao ou injecao de pneumaticos de veiculos e dispositivo para realizacao do processo
BR8102480A (pt) Processo e dispositivo para a producao de esteiras de fibras organicas ou anorganicas
NL181672C (nl) Werkwijze voor het bereiden of vervaardigen van een met siliconen behandeld synthetisch organisch vezelmateriaal; werkwijze voor het bereiden van een siliconen bevattend behandelingsmengsel.
DE3853465D1 (de) Testträger zur Analyse einer Probenflüssigkeit und Verfahren zu seiner Herstellung.
BR8000745A (pt) Processo para a sulfonatacao ou sulfatacao de compostos organicos e dispositivo adequado para realizar o processo
EP0444212A4 (en) Converging filter and method of producing same
ATE90790T1 (de) Verfahren zur herstellung einer festphasenmatrix.
EP0305803A3 (de) Vorrichtung und Verfahren zur Abtrennung von Blutzellen aus Körperflüssigkeiten, die Erythrozyten enthalten, und deren Verwendung
AT378063B (de) Verfahren und vorrichtung zur herstellung von reagensloesungen
KR890006828A (ko) 효소 분석법
ATA260879A (de) Geraet zur oberflaechenstrukturierung von holz- werkstuecken
DE59108355D1 (de) Verfahren zur immunologischen Bestimmung von Liganden
BURGGRAF Photoacoustic spectroscopy of chemically modified surfaces[Ph. D. Thesis- Denver Univ.]
DE59001473D1 (de) Verfahren und vorrichtung zur herstellung von faserbaendern mit parallelisierter faserlage aus wirrfaserkollektiven.
IT7805214A0 (it) Pendente in metallo, preferibilmente prezioso, con pellicola, riproducente motivi ornamentali, trattata secondo il processo dei cristalli liquidi, o trattata secondo processi che attuano lo stesso effetto.
BR7903812A (pt) Reagente de controle de referencia para analise hematologireagente de controle de referencia para analise hematologica multipla e processo de producao do mesmo ca multipla e processo de producao do mesmo

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN