DE3855991D1 - Testsysteme unter Verwendung von Gewebeäquivalenten - Google Patents

Testsysteme unter Verwendung von Gewebeäquivalenten

Info

Publication number
DE3855991D1
DE3855991D1 DE3855991T DE3855991T DE3855991D1 DE 3855991 D1 DE3855991 D1 DE 3855991D1 DE 3855991 T DE3855991 T DE 3855991T DE 3855991 T DE3855991 T DE 3855991T DE 3855991 D1 DE3855991 D1 DE 3855991D1
Authority
DE
Germany
Prior art keywords
tissue
test systems
limited
tissue equivalents
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3855991T
Other languages
English (en)
Other versions
DE3855991T2 (de
Inventor
Eugene Bell
Crispin Weinburg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organogenesis Inc
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21867144&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3855991(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Application granted granted Critical
Publication of DE3855991D1 publication Critical patent/DE3855991D1/de
Publication of DE3855991T2 publication Critical patent/DE3855991T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
DE3855991T 1987-03-31 1988-03-31 Testsysteme unter Verwendung von Gewebeäquivalenten Expired - Fee Related DE3855991T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/032,848 US4835102A (en) 1987-03-31 1987-03-31 Tissue equivalent test systems

Publications (2)

Publication Number Publication Date
DE3855991D1 true DE3855991D1 (de) 1997-09-18
DE3855991T2 DE3855991T2 (de) 1998-01-22

Family

ID=21867144

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3855991T Expired - Fee Related DE3855991T2 (de) 1987-03-31 1988-03-31 Testsysteme unter Verwendung von Gewebeäquivalenten

Country Status (9)

Country Link
US (1) US4835102A (de)
EP (1) EP0295762B1 (de)
JP (1) JP2767803B2 (de)
AT (1) ATE156915T1 (de)
CA (1) CA1305913C (de)
DE (1) DE3855991T2 (de)
ES (1) ES2106010T3 (de)
GR (1) GR3025046T3 (de)
IL (1) IL85599A (de)

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CA2188563C (en) 1994-04-29 2005-08-02 Andrew W. Buirge Stent with collagen
JP2858087B2 (ja) * 1994-09-19 1999-02-17 グンゼ株式会社 組織培養用基材及び組織培養法
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US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
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US20040002772A1 (en) * 1995-04-28 2004-01-01 Organogenesis, Inc. Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US5846188A (en) * 1997-01-17 1998-12-08 Palti; Yoram Sensor utilizing living muscle cells
US6340677B1 (en) 1997-03-11 2002-01-22 Pola Chemical Industries, Inc. Method of evaluation of skin conditioning-ameliorating agents and method of producing compositions for topical application to skin
US7687057B2 (en) * 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6066495A (en) * 1998-03-05 2000-05-23 Tissue Engineering, Inc. Methods and apparatus for the conditioning of ligament replacement tissue
WO1999046285A2 (en) 1998-03-11 1999-09-16 University Of Southern California Method of promoting production of living tissue equivalents
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
US8563232B2 (en) * 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US6293970B1 (en) * 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US7063726B2 (en) * 1998-06-30 2006-06-20 Lifenet Plasticized bone grafts and methods of making and using same
AT407047B (de) * 1998-08-03 2000-11-27 Pfaller Walter Dr Zellkulturvorrichtung
CA2351396C (en) 1998-11-19 2012-08-14 Organogenesis Inc. Bioengineered tissue constructs and methods for producing and using them
US6030789A (en) * 1999-03-10 2000-02-29 The Gillette Company Human conjunctival epithelial cell lines with an extended life span
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
US20060127366A1 (en) * 1999-06-25 2006-06-15 Mitrani Eduardo N Method and device for inducing biological processes by micro-organs
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US6852526B2 (en) * 2000-07-14 2005-02-08 Transform Pharmaceuticals, Inc. Transdermal assay with magnetic clamp
JP2004504585A (ja) * 2000-07-14 2004-02-12 トランスフォーム　ファーマシューティカルズ，インコーポレーティッド． 化合物の組織バリア輸送を最適にするためのシステムおよび方法
AU2002341867A1 (en) * 2001-09-27 2003-04-07 The Wistar Institute Methods and compositions for monitoring cell migration and identifying clinically relevant cytotoxic t lymphocyte activity
US20030166274A1 (en) * 2001-11-15 2003-09-04 Hewitt Charles W. Three-dimensional matrix for producing living tissue equivalents
AU2003234197A1 (en) * 2002-04-22 2003-11-03 Tufts University Multi-dimensional strain bioreactor
AUPS242702A0 (en) * 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US7229820B2 (en) * 2002-06-13 2007-06-12 Wilson Wolf Manufacturing Corporation Apparatus and method for culturing and preserving tissue constructs
US7449307B2 (en) * 2002-10-28 2008-11-11 Transform Pharmaceuticals, Inc. Raised surface assay plate
US6908760B2 (en) * 2002-10-28 2005-06-21 Transform Pharmaceuticals, Inc. Raised surface assay plate
US20040185430A1 (en) * 2002-12-20 2004-09-23 Marc Andre Lefebvre Process for evaluating the cosmetic or dermatological activity of a product and use of plant material
US20090024224A1 (en) 2007-07-16 2009-01-22 Chen Silvia S Implantation of cartilage
EP2183353B1 (de) * 2007-08-22 2015-04-29 ProBioGen AG Kultursystem und verfahren zum testen von immunogenität und immunfunktion in vitro
ES2535956T3 (es) * 2008-01-10 2015-05-19 L'oreal, S.A. Dispositivos y métodos para modelar el sistema inmune
US8647861B2 (en) 2008-07-16 2014-02-11 Children's Medical Center Corporation Organ mimic device with microchannels and methods of use and manufacturing thereof
JP5608282B2 (ja) * 2010-04-05 2014-10-15 イー・エム・デイー・ミリポア・コーポレイシヨン ヒト皮膚様透過性を有するポリマー膜およびこの使用
AU2012223526B2 (en) 2011-02-28 2017-03-09 President And Fellows Of Harvard College Cell culture system
WO2013086486A1 (en) 2011-12-09 2013-06-13 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
EP2725094A1 (de) * 2012-10-29 2014-04-30 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Epithelgewebemodell
WO2015013332A1 (en) 2013-07-22 2015-01-29 President And Fellows Of Harvard College Microfluidic cartridge assembly
WO2015138034A2 (en) 2013-12-20 2015-09-17 President And Fellows Of Harvard College Low shear microfluidic devices and methods of use and manufacturing thereof
AU2015289999B2 (en) 2014-07-14 2020-09-10 President And Fellows Of Harvard College Systems and methods for improved performance of fluidic and microfluidic systems
US10202569B2 (en) 2015-07-24 2019-02-12 President And Fellows Of Harvard College Radial microfluidic devices and methods of use
CN112980690B (zh) * 2019-12-17 2022-10-21 华东数字医学工程研究院 Pdx模型孵育装置和抗肿瘤药物筛选方法
CA3224581A1 (en) * 2021-07-01 2023-01-05 Mary RATZLAFF Device for vitrifying and delivering vitrified bioactive agents

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US4539716A (en) * 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
JPS59500201A (ja) * 1982-02-19 1984-02-16 エンドトロニックス・インコ−ポレ−テッド 生物組織への生理活性物質投与のパターンを制御する方法
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JPS6110136A (ja) * 1984-06-25 1986-01-17 Fumio Itatsu 油圧機器の圧力調整装置
JPS6134832A (ja) * 1984-07-26 1986-02-19 Hitachi Ltd 大口径イオン源
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US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
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Also Published As

Publication number Publication date
DE3855991T2 (de) 1998-01-22
IL85599A (en) 1991-11-21
JPS63296699A (ja) 1988-12-02
EP0295762A3 (de) 1990-07-04
ES2106010T3 (es) 1997-11-01
JP2767803B2 (ja) 1998-06-18
EP0295762B1 (de) 1997-08-13
US4835102A (en) 1989-05-30
CA1305913C (en) 1992-08-04
EP0295762A2 (de) 1988-12-21
GR3025046T3 (en) 1998-01-30
IL85599A0 (en) 1988-08-31
ATE156915T1 (de) 1997-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee