DE3887179T2 - Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. - Google Patents

Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.

Info

Publication number
DE3887179T2
DE3887179T2 DE3887179T DE3887179T DE3887179T2 DE 3887179 T2 DE3887179 T2 DE 3887179T2 DE 3887179 T DE3887179 T DE 3887179T DE 3887179 T DE3887179 T DE 3887179T DE 3887179 T2 DE3887179 T2 DE 3887179T2
Authority
DE
Germany
Prior art keywords
pharmaceutical
preparation
granules
pharmaceutical composition
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3887179T
Other languages
English (en)
Other versions
DE3887179D1 (de
Inventor
Margaretha Olthoff
Boer Leonardus Wilhelmus Th De
Piet Johannes Akkerboom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Europe BV
Original Assignee
BROCADES PHARMA BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8197583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3887179(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BROCADES PHARMA BV filed Critical BROCADES PHARMA BV
Application granted granted Critical
Publication of DE3887179D1 publication Critical patent/DE3887179D1/de
Publication of DE3887179T2 publication Critical patent/DE3887179T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DE3887179T 1987-03-02 1988-02-26 Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. Expired - Lifetime DE3887179T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87200357 1987-03-02

Publications (2)

Publication Number Publication Date
DE3887179D1 DE3887179D1 (de) 1994-03-03
DE3887179T2 true DE3887179T2 (de) 1994-06-16

Family

ID=8197583

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3887179T Expired - Lifetime DE3887179T2 (de) 1987-03-02 1988-02-26 Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.

Country Status (16)

Country Link
US (1) US4950484A (de)
EP (1) EP0281200B1 (de)
JP (1) JPS63301820A (de)
KR (1) KR960009182B1 (de)
CN (1) CN1036763C (de)
AU (1) AU603870B2 (de)
CA (1) CA1338467C (de)
DE (1) DE3887179T2 (de)
DK (1) DK175508B1 (de)
ES (1) ES2061623T3 (de)
FI (1) FI94214C (de)
IE (1) IE70907B1 (de)
IL (1) IL85594A (de)
NO (1) NO174996C (de)
NZ (1) NZ223711A (de)
PT (1) PT86870B (de)

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US5861172A (en) * 1991-05-08 1999-01-19 Laboratorios Beecham Sa Pharmaceutical formulations of compacted granulates of β-lactam antibiotics
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US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
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US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
ATE208618T1 (de) 1995-09-07 2001-11-15 Smithkline Beecham Corp Verwendung einer amoxicillin und clavulanat enthaltenden paediatrischen pharmazeutischen formulierung
US6423341B1 (en) * 1996-02-29 2002-07-23 Fujisawa Pharmaceutical Co., Ltd. β-lactam antibiotic-containing tablet and production thereof
AT407214B (de) * 1996-03-13 2001-01-25 Biochemie Gmbh Verfahren zur herstellung von hilfsstoffefreien agglomeraten aus beta-lactamantibiotika
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
US5837292A (en) * 1996-07-03 1998-11-17 Yamanouchi Europe B.V. Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
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WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
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EP1023065A1 (de) * 1997-08-29 2000-08-02 Dsm N.V. Zusatzfreie granulate
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AU1337999A (en) * 1997-11-17 1999-06-07 Gist-Brocades B.V. Granules comprising clavulanate and one or more excipients
CA2340130A1 (en) 1998-09-25 2000-04-06 Suggy S. Chrai Liquid pharmaceutical for oral delivery
US6692779B2 (en) * 1999-03-26 2004-02-17 The Pillsbury Company Food products with biocontrol preservation
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US20020006433A1 (en) * 1999-04-29 2002-01-17 Nigel P. Davidson Pharmaceutical formulations
US6716453B1 (en) * 1999-05-20 2004-04-06 Verion, Inc. Method for increasing the active loading of compressible composition forms
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
AR025587A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones en dispersion que contienen inhibidores de lipasa
AR028253A1 (es) * 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
EP1330236A2 (de) 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Amoxicillinhaltige arzneizusammensetzungen
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
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US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
BR0307516A (pt) * 2002-02-01 2004-12-07 Pfizer Prod Inc Formas de dosagem de liberação imediata contendo dispersões de uma droga sólida
JP4551092B2 (ja) * 2002-03-06 2010-09-22 協和発酵キリン株式会社 口腔内速崩壊性錠剤
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US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
CN1681497A (zh) * 2002-07-16 2005-10-12 兰贝克赛实验室有限公司 口服给药用的可分散片剂
AU2003247023A1 (en) * 2002-08-02 2004-02-25 Ranbaxy Laboratories Limited A process for the preparation of dispersible tablet of cephalexin
EP1720533B1 (de) * 2004-02-24 2015-03-25 Sandoz Ag Amoxicillin-instantgranulat
US20050244343A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Oral care products comprising silica
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
US20080126195A1 (en) 2004-07-22 2008-05-29 Ritter Andrew J Methods and Compositions for Treating Lactose Intolerance
EP1838287B1 (de) * 2005-01-07 2012-05-23 Sandoz Ag Verfahren zur granulatherstellung mit amoxicillin
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
US8653066B2 (en) 2006-10-09 2014-02-18 Charleston Laboratories, Inc. Pharmaceutical compositions
US8685457B2 (en) * 2007-06-06 2014-04-01 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
US20090162434A1 (en) * 2007-12-21 2009-06-25 Disphar International Bv Mesalazine tablet
EP2240022B1 (de) 2008-01-09 2016-12-28 Charleston Laboratories, Inc. Oxycodone und Promethazine enthaltende zweischichtige Tabletten
JP2012518635A (ja) 2009-02-24 2012-08-16 リター ファーマシューティカルズ インコーポレイテッド プレバイオティック製剤および使用方法
US8785160B2 (en) 2009-02-24 2014-07-22 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
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TR200909786A1 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Sefiksim içeren efervesan tablet ve granül formülasyonu.
TR201010860A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefdinir formulasyonları için üretim yöntemi.
TR201009167A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefalosporin içeren farmasötik granüller.
JP6077555B2 (ja) * 2012-02-15 2017-02-08 武田薬品工業株式会社 錠剤
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CN106255512B (zh) * 2014-04-21 2021-01-01 株式会社大赛璐 含有微小纤维状纤维素的崩解性颗粒组合物
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Also Published As

Publication number Publication date
DK108888A (da) 1988-09-03
CN1036763C (zh) 1997-12-24
EP0281200B1 (de) 1994-01-19
CN88101104A (zh) 1988-12-21
FI94214B (fi) 1995-04-28
DK175508B1 (da) 2004-11-15
IE70907B1 (en) 1997-01-15
FI94214C (fi) 1995-08-10
FI880928A (fi) 1988-09-03
IL85594A (en) 1992-11-15
NO174996C (no) 1994-08-17
AU603870B2 (en) 1990-11-29
KR880010757A (ko) 1988-10-24
PT86870B (pt) 1992-05-29
JPS63301820A (ja) 1988-12-08
NO174996B (no) 1994-05-09
AU1252088A (en) 1988-09-01
NO880904D0 (no) 1988-03-01
ES2061623T3 (es) 1994-12-16
PT86870A (pt) 1988-04-01
KR960009182B1 (ko) 1996-07-16
DE3887179D1 (de) 1994-03-03
DK108888D0 (da) 1988-03-01
CA1338467C (en) 1996-07-23
NZ223711A (en) 1989-08-29
FI880928A0 (fi) 1988-02-29
NO880904L (no) 1988-09-05
US4950484A (en) 1990-08-21
EP0281200A1 (de) 1988-09-07
IE880584L (en) 1988-09-02

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