DE502005002679D1 - Mit einem organischem rest verbundenes polypeptid - Google Patents
Mit einem organischem rest verbundenes polypeptidInfo
- Publication number
- DE502005002679D1 DE502005002679D1 DE502005002679T DE502005002679T DE502005002679D1 DE 502005002679 D1 DE502005002679 D1 DE 502005002679D1 DE 502005002679 T DE502005002679 T DE 502005002679T DE 502005002679 T DE502005002679 T DE 502005002679T DE 502005002679 D1 DE502005002679 D1 DE 502005002679D1
- Authority
- DE
- Germany
- Prior art keywords
- modified
- polypeptide
- peptides
- side chains
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004031258A DE102004031258A1 (de) | 2004-06-29 | 2004-06-29 | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
PCT/DE2005/001151 WO2006000209A1 (de) | 2004-06-29 | 2005-06-29 | Mit einem organischem rest verbundenes polypeptid |
Publications (1)
Publication Number | Publication Date |
---|---|
DE502005002679D1 true DE502005002679D1 (de) | 2008-03-13 |
Family
ID=35058757
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE102004031258A Withdrawn DE102004031258A1 (de) | 2004-06-29 | 2004-06-29 | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
DE502005002679T Active DE502005002679D1 (de) | 2004-06-29 | 2005-06-29 | Mit einem organischem rest verbundenes polypeptid |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE102004031258A Withdrawn DE102004031258A1 (de) | 2004-06-29 | 2004-06-29 | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
Country Status (8)
Country | Link |
---|---|
US (2) | US20080281069A1 (de) |
EP (2) | EP1939211A1 (de) |
AT (1) | ATE384734T1 (de) |
AU (1) | AU2005256304B2 (de) |
CA (1) | CA2572245A1 (de) |
DE (2) | DE102004031258A1 (de) |
ES (1) | ES2300033T3 (de) |
WO (1) | WO2006000209A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR060768A1 (es) * | 2006-05-05 | 2008-07-10 | Millennium Pharm Inc | Compuestos de imidazol sustituidos inhibidores del factor x, composiciones farmaceuticas que los contienen y usos como agentes antitromboticos. |
ES2301453B1 (es) * | 2008-02-18 | 2009-02-16 | Universidad De Murcia | Procedimiento de obtencion de o-difenoles. |
NZ594868A (en) * | 2009-03-06 | 2014-01-31 | Biopolymer Technologies Ltd | Protein-containing emulsions and adhesives, and manufacture and use thereof |
CA2753896C (en) | 2009-03-06 | 2018-08-28 | Biopolymer Technologies, Ltd. | Protein-containing foams, manufacture and use thereof |
EP2576661B1 (de) * | 2010-06-07 | 2016-12-14 | Evertree | Proteinhaltiger klebstoff, dessen herstellung und dessen anwendung |
US20130065012A1 (en) | 2011-09-09 | 2013-03-14 | Anthony A. Parker | Protein-containing adhesives, and manufacture and use thereof |
SI2753633T1 (sl) * | 2011-09-09 | 2017-05-31 | Evertree | Adhezivi, ki vsebujejo protein in njihova izdelava in uporaba |
US9873823B2 (en) | 2012-07-30 | 2018-01-23 | Evertree | Protein adhesives containing an anhydride, carboxylic acid, and/or carboxylate salt compound and their use |
US10765748B2 (en) * | 2014-07-11 | 2020-09-08 | University Of Akron | Composition and methods for tethering bioactive peptides to metal oxide surfaces |
JP2017043547A (ja) * | 2015-08-24 | 2017-03-02 | 国立研究開発法人理化学研究所 | ポリペプチドを結合した成長因子及びその利用 |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL55385C (de) * | 1940-06-14 | 1900-01-01 | ||
US2430950A (en) * | 1944-08-11 | 1947-11-18 | Du Pont | Resin modified n-alkoxymethyl polyamide and process for obtaining same |
DE2708018A1 (de) * | 1977-02-24 | 1978-09-07 | Boehringer Mannheim Gmbh | An polyamid fixiertes biologisch aktives protein und verfahren zu seiner herstellung |
US4585585A (en) * | 1984-03-07 | 1986-04-29 | University Of Connecticut Research & Development Corporation | Decapeptides produced from bioadhesive polyphenolic proteins |
US5202256A (en) * | 1984-09-13 | 1993-04-13 | Enzon Labs, Inc. | Bioadhesive precursor protein expression vectors |
US4593073A (en) * | 1985-04-23 | 1986-06-03 | The Royal Institution For The Advancement Of Learing (Mcgill Univ.) | Polymer resins with amino acid containing pendants for sorption of bile pigments and bile acids |
US5108923A (en) * | 1986-04-25 | 1992-04-28 | Collaborative Research, Inc. | Bioadhesives for cell and tissue adhesion |
DK163987A (da) * | 1986-04-25 | 1987-10-26 | Bio Polymers Inc | Fremgangsmaade til fremstilling af dopa-holdige bioklaebende proteiner ud fra tyrosin-holdige proteiner |
US6184348B1 (en) * | 1986-11-04 | 2001-02-06 | Protein Polymer Technologies | Functional recombinantly prepared synthetic protein polymer |
JPH02501706A (ja) * | 1986-11-24 | 1990-06-14 | ジェネックス・コーポレーション | 生物学的接着物質 |
AU1572588A (en) * | 1987-03-12 | 1988-10-10 | Genex Corp. | Production of bioadhesive precursor protein analogs by genetically-engineered organisms |
US5171779A (en) * | 1988-07-18 | 1992-12-15 | Industrial Technology Research Institute | Use of plasma to immobilize protein on polymeric surfaces |
US4908404A (en) * | 1988-08-22 | 1990-03-13 | Biopolymers, Inc. | Synthetic amino acid-and/or peptide-containing graft copolymers |
US5071909A (en) * | 1989-07-26 | 1991-12-10 | Millipore Corporation | Immobilization of proteins and peptides on insoluble supports |
US5098999A (en) * | 1989-08-23 | 1992-03-24 | Hitachi Chemical Company | Amino-protected dopa derivative and production thereof |
US5294369A (en) * | 1990-12-05 | 1994-03-15 | Akzo N.V. | Ligand gold bonding |
US5197973A (en) * | 1990-12-14 | 1993-03-30 | Creative Biomolecules, Inc. | Synthetic bioadhesive |
US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
US5578442A (en) * | 1992-03-23 | 1996-11-26 | Vivorx, Inc. | Graft copolymers of polycationic species and water-soluble polymers, and use therefor |
US6221958B1 (en) * | 1993-01-06 | 2001-04-24 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
PT876165E (pt) * | 1995-12-18 | 2006-10-31 | Angiotech Biomaterials Corp | Composicoes de polimeros reticulados e processos para a sua utilizacao |
US6239255B1 (en) * | 1997-08-29 | 2001-05-29 | Clement E. Furlong | Versatile surface plasmon resonance biosensors |
US6884842B2 (en) * | 1997-10-14 | 2005-04-26 | Alnis Biosciences, Inc. | Molecular compounds having complementary surfaces to targets |
ES2201571T3 (es) * | 1997-11-24 | 2004-03-16 | Morphoplant Gmbh | Procedimiento para la inmovilizacion de moleculas mediadoras sobre materiales de implantes inorganicos y metalicos. |
US6506577B1 (en) * | 1998-03-19 | 2003-01-14 | The Regents Of The University Of California | Synthesis and crosslinking of catechol containing copolypeptides |
US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
US6485718B1 (en) * | 1999-04-13 | 2002-11-26 | Pharmacia Corporation | Site specific ligation of proteins to synthetic particles |
GB9912911D0 (en) * | 1999-06-04 | 1999-08-04 | Zeneca Ltd | Chemical process |
DE60027606T2 (de) * | 1999-12-17 | 2007-01-25 | Biopolymer Products Of Sweden Ab | Polyphenolisches protein enthaltende bioadhäsive zusammensetzung |
US20010031469A1 (en) * | 2000-01-03 | 2001-10-18 | Stefano Volinia | Methods for the detection of modified peptides, proteins and other molecules |
US7351540B1 (en) * | 2000-03-17 | 2008-04-01 | Merck Patent Gmbh | Protein isolation and analysis |
US6565960B2 (en) * | 2000-06-01 | 2003-05-20 | Shriners Hospital Of Children | Polymer composite compositions |
DE10037850A1 (de) * | 2000-08-01 | 2002-02-21 | Herbert P Jennissen | Verfahren zur Herstellung bioaktiver Implantatoberflächen |
GB0026560D0 (en) * | 2000-10-30 | 2000-12-13 | Novartis Ag | Organic compounds |
WO2002053606A1 (en) * | 2001-01-04 | 2002-07-11 | Council Of Scientific And Industrial Research | A new linker based solid support for peptide and small molecule organic synthesis |
US8815793B2 (en) * | 2001-07-20 | 2014-08-26 | Northwestern University | Polymeric compositions and related methods of use |
WO2003008376A2 (en) * | 2001-07-20 | 2003-01-30 | Northwestern University | Adhesive dopa-containing polymers and related methods of use |
US7045543B2 (en) * | 2001-11-05 | 2006-05-16 | Enzrel Inc. | Covalent conjugates of biologically-active compounds with amino acids and amino acid derivatives for targeting to physiologically-protected sites |
US20040009530A1 (en) * | 2002-01-16 | 2004-01-15 | Wilson David S. | Engineered binding proteins |
US6914126B2 (en) * | 2002-04-10 | 2005-07-05 | Keraplast Technologies, Ltd. | Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks |
US8591951B2 (en) * | 2002-05-15 | 2013-11-26 | Joachim B. Kohn | Tri-block copolymers for nanosphere-based drug delivery |
FR2843117B1 (fr) * | 2002-07-30 | 2004-10-15 | Flamel Tech Sa | Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques |
WO2004015094A1 (en) * | 2002-08-06 | 2004-02-19 | Dsm Ip Assets B.V. | Process for the preparation of l-3,4-dihydroxyphenylalanine by aerobic fermentation of a microorganism |
US20040078090A1 (en) * | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
EP1562630A4 (de) * | 2002-10-31 | 2009-02-18 | Univ Northwestern | INJIZIERBARE BIOADHûSIVE POLYMERE HYDROGELEUND RELEVANTE VERFAHREN ZUR ENZYMATISCHEN HERSTELLUNG |
US6982298B2 (en) * | 2003-01-10 | 2006-01-03 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
EP1604026A1 (de) * | 2003-03-20 | 2005-12-14 | Sabanci Universitesi | Ringförmiges, rekombinantes dna plasmidkonstrukt und dessen protein-produkte sowie methoden zur präparation und immoblisierung von proteinen auf trägermaterialien |
OA13164A (en) * | 2003-05-12 | 2006-12-13 | Affymax Inc | Novel peptides that bind to the erythropoietin receptor. |
WO2005005548A1 (ja) * | 2003-07-09 | 2005-01-20 | Tokyo University Of Science, Educational Foundation | 多孔質粒子とポリマー分子のコンジュゲートならびにその使用 |
US7074615B2 (en) * | 2003-08-15 | 2006-07-11 | Becton, Dickinson And Company | Peptides for enhanced cell attachment and cell growth |
JP5657850B2 (ja) * | 2003-10-14 | 2015-01-21 | ザ スクリプス リサーチ インスティテュート | 酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ |
WO2005056708A2 (en) * | 2003-12-09 | 2005-06-23 | Spherics, Inc. | Bioadhesive polymers with catechol functionality |
MXPA06010505A (es) * | 2004-03-15 | 2006-12-19 | Nektar Therapeutics Al Corp | Composiciones y conjugados, basados en polimeros, de inhibidores de ingreso de vih. |
WO2005092920A1 (en) * | 2004-03-26 | 2005-10-06 | Postech Foundation | Mussel bioadhesive |
US6995012B1 (en) * | 2004-08-09 | 2006-02-07 | Battelle Energy Alliance, Llc | Cloning and expression of recombinant adhesive protein MEFP-2 of the blue mussel, Mytilus edulis |
US20060115449A1 (en) * | 2004-11-30 | 2006-06-01 | Advanced Cardiovascular Systems, Inc. | Bioabsorbable, biobeneficial, tyrosine-based polymers for use in drug eluting stent coatings |
-
2004
- 2004-06-29 DE DE102004031258A patent/DE102004031258A1/de not_active Withdrawn
-
2005
- 2005-06-29 AT AT05761699T patent/ATE384734T1/de active
- 2005-06-29 WO PCT/DE2005/001151 patent/WO2006000209A1/de active IP Right Grant
- 2005-06-29 US US11/631,231 patent/US20080281069A1/en not_active Abandoned
- 2005-06-29 ES ES05761699T patent/ES2300033T3/es active Active
- 2005-06-29 DE DE502005002679T patent/DE502005002679D1/de active Active
- 2005-06-29 EP EP08150498A patent/EP1939211A1/de not_active Withdrawn
- 2005-06-29 CA CA002572245A patent/CA2572245A1/en not_active Abandoned
- 2005-06-29 AU AU2005256304A patent/AU2005256304B2/en not_active Ceased
- 2005-06-29 EP EP05761699A patent/EP1763535B8/de not_active Not-in-force
-
2016
- 2016-12-16 US US15/530,271 patent/US20170166619A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE384734T1 (de) | 2008-02-15 |
EP1763535A1 (de) | 2007-03-21 |
EP1763535B1 (de) | 2008-01-23 |
CA2572245A1 (en) | 2006-01-05 |
US20170166619A1 (en) | 2017-06-15 |
EP1763535B8 (de) | 2008-03-19 |
AU2005256304A1 (en) | 2006-01-05 |
US20080281069A1 (en) | 2008-11-13 |
DE102004031258A1 (de) | 2006-02-09 |
AU2005256304B2 (en) | 2010-09-30 |
ES2300033T3 (es) | 2008-06-01 |
WO2006000209A1 (de) | 2006-01-05 |
EP1939211A1 (de) | 2008-07-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE502005002679D1 (de) | Mit einem organischem rest verbundenes polypeptid | |
RU2007127848A (ru) | Аффинные лиганды, связывающие антитела | |
IL209576A (en) | Α1-il antibodies and methods of use | |
WO2008077406A3 (en) | Coupling of elements | |
DK1412487T3 (da) | Assayelektroder der har immobiliserede lipid/proteinlag og fremgangsmåder til at fremstille og anvende disse | |
WO2004012658A3 (en) | Method and device for protein delivery into cells | |
WO2006091231A3 (en) | Biosynthetic polypeptides utilizing non-naturally encoded amino acids | |
NO20063026L (no) | Antistoffer | |
PE20091004A1 (es) | Proteinas de union a antigenos c-fms humanos | |
ATE457355T1 (de) | Verfahren und dna-konstrukte zur produktion von polypeptiden mit hoher ausbeute | |
WO2008113005A3 (en) | Methods to improve the stability of cellular adhesive proteins and peptides | |
WO2006093529A3 (en) | Covalent tethering of functional groups to proteins and substrates therefor | |
EP2322552A3 (de) | IL-1 beta bindende Antikörper und deren Fragmente | |
WO2008153745A3 (en) | Compositions and methods for producing bioactive fusion proteins | |
WO2005071414A3 (en) | Kit for immobilizing organic substance, organic substance-immobilized structure, and manufacturing methods therefor | |
WO2007039231A3 (en) | Method of producing a modified (poly)peptide | |
WO2006047680A3 (en) | Lactobacillus acidophilus nucleic acids and uses thereof | |
WO2006113475A3 (en) | Methods and compositions to modulate adhesion and stress tolerance in bacteria | |
WO2003089451A3 (en) | Antibodies specific for mucin polypeptide | |
WO2008142664A3 (en) | Exposed thymidine kinase 1 peptides, ligands and methods employing the same | |
ATE451618T1 (de) | Verfahren zur identifizierung von epitopen in zusammenhang mit immunogenität bei biopharmazeutika | |
WO2006094813A3 (en) | Dimeric or multimeric microproteins | |
WO2009125318A3 (en) | Selective enrichment of n-terminally modified peptides from complex samples | |
DK1725580T3 (da) | Isosterisk transformation | |
WO2006097564A3 (es) | Nueva proteina epcr soluble de origen no proteolitico y su uso |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: MORPHOPLANT GMBH, 44801 BOCHUM, DE |
|
8364 | No opposition during term of opposition |