DE502005006955D1 - N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes - Google Patents
N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetesInfo
- Publication number
- DE502005006955D1 DE502005006955D1 DE502005006955T DE502005006955T DE502005006955D1 DE 502005006955 D1 DE502005006955 D1 DE 502005006955D1 DE 502005006955 T DE502005006955 T DE 502005006955T DE 502005006955 T DE502005006955 T DE 502005006955T DE 502005006955 D1 DE502005006955 D1 DE 502005006955D1
- Authority
- DE
- Germany
- Prior art keywords
- peroxisomic
- ambericide
- ylmethoxymethyl
- proliferator
- hyperlipidemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004039509A DE102004039509B4 (de) | 2004-08-14 | 2004-08-14 | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
PCT/EP2005/008282 WO2006018116A1 (de) | 2004-08-14 | 2005-07-30 | N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und werwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE502005006955D1 true DE502005006955D1 (de) | 2009-05-07 |
Family
ID=35385508
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE102004039509A Expired - Fee Related DE102004039509B4 (de) | 2004-08-14 | 2004-08-14 | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE502005006955T Active DE502005006955D1 (de) | 2004-08-14 | 2005-07-30 | N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE102004039509A Expired - Fee Related DE102004039509B4 (de) | 2004-08-14 | 2004-08-14 | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Country Status (20)
Country | Link |
---|---|
US (1) | US7598281B2 (de) |
EP (1) | EP1789403B1 (de) |
JP (1) | JP2008509892A (de) |
KR (1) | KR20070040812A (de) |
CN (1) | CN101006066A (de) |
AR (1) | AR053526A1 (de) |
AT (1) | ATE426596T1 (de) |
AU (1) | AU2005274493A1 (de) |
BR (1) | BRPI0514359A (de) |
CA (1) | CA2576554A1 (de) |
DE (2) | DE102004039509B4 (de) |
DK (1) | DK1789403T3 (de) |
ES (1) | ES2324675T3 (de) |
IL (1) | IL181009A0 (de) |
MX (1) | MX2007000614A (de) |
PE (1) | PE20060640A1 (de) |
PT (1) | PT1789403E (de) |
TW (1) | TW200621732A (de) |
UY (1) | UY29065A1 (de) |
WO (1) | WO2006018116A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6113562A (en) | 1998-06-01 | 2000-09-05 | Peter M. Bonutti | Shoulder orthosis |
US6502577B1 (en) | 2000-09-18 | 2003-01-07 | Peter M. Bonutti | Method for moving finger joints |
US6503213B2 (en) | 2000-12-01 | 2003-01-07 | Peter M. Bonutti | Method of using a neck brace |
US6575926B2 (en) | 2000-12-15 | 2003-06-10 | Bonutti 2003 Trust-A | Myofascial strap |
US8066656B2 (en) | 2005-10-28 | 2011-11-29 | Bonutti Research, Inc. | Range of motion device |
US7452342B2 (en) | 2004-03-08 | 2008-11-18 | Bonutti Research Inc. | Range of motion device |
US8012108B2 (en) | 2005-08-12 | 2011-09-06 | Bonutti Research, Inc. | Range of motion system and method |
CN101272784A (zh) | 2005-09-29 | 2008-09-24 | 塞诺菲-安万特股份有限公司 | 苯基-和吡啶基-1,2,4-噁二唑酮衍生物、它们的制备方法和它们作为药物的用途 |
US8920346B2 (en) | 2007-02-05 | 2014-12-30 | Bonutti Research Inc. | Knee orthosis |
US8273043B2 (en) | 2007-07-25 | 2012-09-25 | Bonutti Research, Inc. | Orthosis apparatus and method of using an orthosis apparatus |
US8905950B2 (en) | 2008-03-04 | 2014-12-09 | Bonutti Research, Inc. | Shoulder ROM orthosis |
EP2486923B1 (de) * | 2011-02-11 | 2015-09-09 | Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG | Histon-Deacetylase (HDAC) hemmende Verbindungen und Verfahren zu deren Herstellung |
US9402759B2 (en) | 2013-02-05 | 2016-08-02 | Bonutti Research, Inc. | Cervical traction systems and method |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0200997A3 (en) * | 1999-04-28 | 2003-03-28 | Sanofi Aventis Deutschland | Tri-aryl acid derivatives as ppar receptor ligands and pharmaceutical compositions containing them |
JP4316787B2 (ja) * | 2000-01-11 | 2009-08-19 | 壽製薬株式会社 | エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、 |
PL208515B1 (pl) * | 2001-08-31 | 2011-05-31 | Sanofi Aventis Deutschland | Pochodne diarylocykloalkilowe, środki lecznicze zawierające te związki oraz ich zastosowanie jako aktywatorów PPAR |
DE10308355A1 (de) * | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
-
2004
- 2004-08-14 DE DE102004039509A patent/DE102004039509B4/de not_active Expired - Fee Related
-
2005
- 2005-07-30 JP JP2007525216A patent/JP2008509892A/ja not_active Abandoned
- 2005-07-30 ES ES05773889T patent/ES2324675T3/es active Active
- 2005-07-30 DK DK05773889T patent/DK1789403T3/da active
- 2005-07-30 KR KR1020077003480A patent/KR20070040812A/ko not_active Application Discontinuation
- 2005-07-30 BR BRPI0514359-4A patent/BRPI0514359A/pt not_active IP Right Cessation
- 2005-07-30 WO PCT/EP2005/008282 patent/WO2006018116A1/de active Application Filing
- 2005-07-30 AU AU2005274493A patent/AU2005274493A1/en not_active Abandoned
- 2005-07-30 MX MX2007000614A patent/MX2007000614A/es active IP Right Grant
- 2005-07-30 EP EP05773889A patent/EP1789403B1/de not_active Not-in-force
- 2005-07-30 CN CNA2005800276576A patent/CN101006066A/zh active Pending
- 2005-07-30 CA CA002576554A patent/CA2576554A1/en not_active Abandoned
- 2005-07-30 AT AT05773889T patent/ATE426596T1/de not_active IP Right Cessation
- 2005-07-30 PT PT05773889T patent/PT1789403E/pt unknown
- 2005-07-30 DE DE502005006955T patent/DE502005006955D1/de active Active
- 2005-08-05 PE PE2005000910A patent/PE20060640A1/es not_active Application Discontinuation
- 2005-08-11 AR ARP050103352A patent/AR053526A1/es not_active Application Discontinuation
- 2005-08-11 TW TW094127240A patent/TW200621732A/zh unknown
- 2005-08-12 UY UY29065A patent/UY29065A1/es unknown
-
2007
- 2007-01-28 IL IL181009A patent/IL181009A0/en unknown
- 2007-02-07 US US11/672,302 patent/US7598281B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101006066A (zh) | 2007-07-25 |
EP1789403A1 (de) | 2007-05-30 |
US7598281B2 (en) | 2009-10-06 |
KR20070040812A (ko) | 2007-04-17 |
AR053526A1 (es) | 2007-05-09 |
UY29065A1 (es) | 2006-02-24 |
JP2008509892A (ja) | 2008-04-03 |
DK1789403T3 (da) | 2009-07-06 |
ATE426596T1 (de) | 2009-04-15 |
EP1789403B1 (de) | 2009-03-25 |
AU2005274493A1 (en) | 2006-02-23 |
ES2324675T3 (es) | 2009-08-12 |
DE102004039509B4 (de) | 2006-09-21 |
CA2576554A1 (en) | 2006-02-23 |
PT1789403E (pt) | 2009-05-19 |
WO2006018116A1 (de) | 2006-02-23 |
PE20060640A1 (es) | 2006-07-27 |
MX2007000614A (es) | 2007-03-30 |
US20070197605A1 (en) | 2007-08-23 |
BRPI0514359A (pt) | 2008-06-10 |
DE102004039509A1 (de) | 2006-03-23 |
IL181009A0 (en) | 2007-07-04 |
TW200621732A (en) | 2006-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |