DE502005006955D1 - N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes - Google Patents

N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes

Info

Publication number: DE502005006955D1
Authority: DE; Germany
Prior art keywords: peroxisomic; ambericide; ylmethoxymethyl; proliferator; hyperlipidemia
Prior art date: 2004-08-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

DE502005006955T

Other languages

English (en)

Inventor

Heiner Glombik

Christian Stapper

Eugen Falk

Stefanie Keil

Hans-Ludwig Schaefer

Wolfgang Wendler

Stephanie Knieps

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis Deutschland GmbH

Original Assignee

Sanofi Aventis Deutschland GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-08-14

Filing date

2005-07-30

Publication date

2009-05-07

2005-07-30 Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH

2009-05-07 Publication of DE502005006955D1 publication Critical patent/DE502005006955D1/de

Status Active legal-status Critical Current

2025-07-31 Anticipated expiration legal-status Critical

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

DE502005006955T 2004-08-14 2005-07-30 N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes Active DE502005006955D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102004039509A DE102004039509B4 (de)	2004-08-14	2004-08-14	Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP2005/008282 WO2006018116A1 (de)	2004-08-14	2005-07-30	N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und werwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes

Publications (1)

Publication Number	Publication Date
DE502005006955D1 true DE502005006955D1 (de)	2009-05-07

Family

ID=35385508

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE102004039509A Expired - Fee Related DE102004039509B4 (de)	2004-08-14	2004-08-14	Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE502005006955T Active DE502005006955D1 (de)	2004-08-14	2005-07-30	N-(phenyl-oxazol-4-ylmethoxymethyl)-cyclohexyl-bernsteinsäureamid derivate und verwandte verbindungen als ppar-liganden (peroxisomen-proliferatoren-aktivierte rezeptoren) zur behandlung von hyperlipidämie und diabetes

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DE102004039509A Expired - Fee Related DE102004039509B4 (de)	2004-08-14	2004-08-14	Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Country Status (20)

Country	Link
US (1)	US7598281B2 (de)
EP (1)	EP1789403B1 (de)
JP (1)	JP2008509892A (de)
KR (1)	KR20070040812A (de)
CN (1)	CN101006066A (de)
AR (1)	AR053526A1 (de)
AT (1)	ATE426596T1 (de)
AU (1)	AU2005274493A1 (de)
BR (1)	BRPI0514359A (de)
CA (1)	CA2576554A1 (de)
DE (2)	DE102004039509B4 (de)
DK (1)	DK1789403T3 (de)
ES (1)	ES2324675T3 (de)
IL (1)	IL181009A0 (de)
MX (1)	MX2007000614A (de)
PE (1)	PE20060640A1 (de)
PT (1)	PT1789403E (de)
TW (1)	TW200621732A (de)
UY (1)	UY29065A1 (de)
WO (1)	WO2006018116A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6113562A (en)	1998-06-01	2000-09-05	Peter M. Bonutti	Shoulder orthosis
US6502577B1 (en)	2000-09-18	2003-01-07	Peter M. Bonutti	Method for moving finger joints
US6503213B2 (en)	2000-12-01	2003-01-07	Peter M. Bonutti	Method of using a neck brace
US6575926B2 (en)	2000-12-15	2003-06-10	Bonutti 2003 Trust-A	Myofascial strap
US8066656B2 (en)	2005-10-28	2011-11-29	Bonutti Research, Inc.	Range of motion device
US7452342B2 (en)	2004-03-08	2008-11-18	Bonutti Research Inc.	Range of motion device
US8012108B2 (en)	2005-08-12	2011-09-06	Bonutti Research, Inc.	Range of motion system and method
BRPI0617207A2 (pt)	2005-09-29	2011-07-19	Sanofi Aventis	derivados de fenil-1,2,4-oxadiazolona, processos para sua preparação e seu uso como produtos farmacêuticos
WO2008097989A2 (en)	2007-02-05	2008-08-14	Bonutti Research Inc.	Knee orthosis
EP2178475A1 (de)	2007-07-25	2010-04-28	Bonutti Research Inc.	Orthosevorrichtung und verfahren zur verwendung einer orthosevorrichtung
US8905950B2 (en)	2008-03-04	2014-12-09	Bonutti Research, Inc.	Shoulder ROM orthosis
EP2486923B1 (de) *	2011-02-11	2015-09-09	Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG	Histon-Deacetylase (HDAC) hemmende Verbindungen und Verfahren zu deren Herstellung
US9402759B2 (en)	2013-02-05	2016-08-02	Bonutti Research, Inc.	Cervical traction systems and method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1183113C (zh) *	1999-04-28	2005-01-05	阿文蒂斯药物德国有限公司	作为ppar受体配体的三芳基酸衍生物
JP4316787B2 (ja) *	2000-01-11	2009-08-19	壽製薬株式会社	エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、
AU2002333456B2 (en) *	2001-08-31	2008-07-17	Sanofi-Aventis Deutschland Gmbh	Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as PPAR activators
DE10308355A1 (de) *	2003-02-27	2004-12-23	Aventis Pharma Deutschland Gmbh	Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel

2004
- 2004-08-14 DE DE102004039509A patent/DE102004039509B4/de not_active Expired - Fee Related
2005
- 2005-07-30 AU AU2005274493A patent/AU2005274493A1/en not_active Abandoned
- 2005-07-30 MX MX2007000614A patent/MX2007000614A/es active IP Right Grant
- 2005-07-30 JP JP2007525216A patent/JP2008509892A/ja not_active Abandoned
- 2005-07-30 WO PCT/EP2005/008282 patent/WO2006018116A1/de active Application Filing
- 2005-07-30 DK DK05773889T patent/DK1789403T3/da active
- 2005-07-30 PT PT05773889T patent/PT1789403E/pt unknown
- 2005-07-30 CA CA002576554A patent/CA2576554A1/en not_active Abandoned
- 2005-07-30 AT AT05773889T patent/ATE426596T1/de not_active IP Right Cessation
- 2005-07-30 ES ES05773889T patent/ES2324675T3/es active Active
- 2005-07-30 EP EP05773889A patent/EP1789403B1/de not_active Not-in-force
- 2005-07-30 CN CNA2005800276576A patent/CN101006066A/zh active Pending
- 2005-07-30 DE DE502005006955T patent/DE502005006955D1/de active Active
- 2005-07-30 BR BRPI0514359-4A patent/BRPI0514359A/pt not_active IP Right Cessation
- 2005-07-30 KR KR1020077003480A patent/KR20070040812A/ko not_active Application Discontinuation
- 2005-08-05 PE PE2005000910A patent/PE20060640A1/es not_active Application Discontinuation
- 2005-08-11 TW TW094127240A patent/TW200621732A/zh unknown
- 2005-08-11 AR ARP050103352A patent/AR053526A1/es not_active Application Discontinuation
- 2005-08-12 UY UY29065A patent/UY29065A1/es unknown
2007
- 2007-01-28 IL IL181009A patent/IL181009A0/en unknown
- 2007-02-07 US US11/672,302 patent/US7598281B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2324675T3 (es)	2009-08-12
DE102004039509A1 (de)	2006-03-23
IL181009A0 (en)	2007-07-04
PT1789403E (pt)	2009-05-19
KR20070040812A (ko)	2007-04-17
ATE426596T1 (de)	2009-04-15
MX2007000614A (es)	2007-03-30
DK1789403T3 (da)	2009-07-06
US20070197605A1 (en)	2007-08-23
CN101006066A (zh)	2007-07-25
TW200621732A (en)	2006-07-01
WO2006018116A1 (de)	2006-02-23
EP1789403A1 (de)	2007-05-30
DE102004039509B4 (de)	2006-09-21
AU2005274493A1 (en)	2006-02-23
US7598281B2 (en)	2009-10-06
CA2576554A1 (en)	2006-02-23
BRPI0514359A (pt)	2008-06-10
JP2008509892A (ja)	2008-04-03
UY29065A1 (es)	2006-02-24
AR053526A1 (es)	2007-05-09
EP1789403B1 (de)	2009-03-25
PE20060640A1 (es)	2006-07-27

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Legal Events

Date	Code	Title	Description
2010-04-15	8364	No opposition during term of opposition