DE58903808D1 - Verfahren zur herstellung von 3,5-dimethyl-4-methoxypyridinderivaten sowie neues zwischenprodukt hierfuer. - Google Patents

Verfahren zur herstellung von 3,5-dimethyl-4-methoxypyridinderivaten sowie neues zwischenprodukt hierfuer.

Info

Publication number
DE58903808D1
DE58903808D1 DE8989119640T DE58903808T DE58903808D1 DE 58903808 D1 DE58903808 D1 DE 58903808D1 DE 8989119640 T DE8989119640 T DE 8989119640T DE 58903808 T DE58903808 T DE 58903808T DE 58903808 D1 DE58903808 D1 DE 58903808D1
Authority
DE
Germany
Prior art keywords
dimethyl
methoxypyridine
producing
intermediate product
new intermediate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989119640T
Other languages
English (en)
Inventor
Karl Dr Dipl Ing Baumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hafslund Nycomed Pharma AG
Original Assignee
Hafslund Nycomed Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hafslund Nycomed Pharma AG filed Critical Hafslund Nycomed Pharma AG
Application granted granted Critical
Publication of DE58903808D1 publication Critical patent/DE58903808D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/68—One oxygen atom attached in position 4
DE8989119640T 1988-11-15 1989-10-23 Verfahren zur herstellung von 3,5-dimethyl-4-methoxypyridinderivaten sowie neues zwischenprodukt hierfuer. Expired - Fee Related DE58903808D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0278988A AT391693B (de) 1988-11-15 1988-11-15 Verfahren zur herstellung von 3-5-dimethyl-4methoxypyridinderivaten sowie neues zwischenprodukt hierfuer

Publications (1)

Publication Number Publication Date
DE58903808D1 true DE58903808D1 (de) 1993-04-22

Family

ID=3540308

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3840372A Withdrawn DE3840372A1 (de) 1988-11-15 1988-11-30 Verfahren zur herstellung von 3,5-dimethyl-4-methoxypyridinderivaten sowie neues zwischenprodukt hierfuer
DE8989119640T Expired - Fee Related DE58903808D1 (de) 1988-11-15 1989-10-23 Verfahren zur herstellung von 3,5-dimethyl-4-methoxypyridinderivaten sowie neues zwischenprodukt hierfuer.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3840372A Withdrawn DE3840372A1 (de) 1988-11-15 1988-11-30 Verfahren zur herstellung von 3,5-dimethyl-4-methoxypyridinderivaten sowie neues zwischenprodukt hierfuer

Country Status (24)

Country Link
US (1) US5066810A (de)
EP (1) EP0369208B1 (de)
JP (1) JPH02180868A (de)
KR (1) KR900007803A (de)
CN (1) CN1042705A (de)
AT (2) AT391693B (de)
AU (1) AU628100B2 (de)
CA (1) CA2002757A1 (de)
CS (1) CS276357B6 (de)
DD (1) DD284877A5 (de)
DE (2) DE3840372A1 (de)
DK (1) DK568989A (de)
ES (1) ES2053906T3 (de)
FI (1) FI895389A0 (de)
GR (1) GR3007391T3 (de)
HU (1) HU207995B (de)
IL (1) IL92152A (de)
NO (1) NO894410L (de)
NZ (1) NZ231252A (de)
PH (1) PH25813A (de)
PT (1) PT92307B (de)
SU (1) SU1745121A3 (de)
YU (1) YU216389A (de)
ZA (1) ZA898273B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2024357A6 (es) * 1990-12-05 1992-02-16 Genesis Para La Investigacion Procedimiento de obtencion de halohidrato de 2-halometil-3,5-dimetil-4-metoxipiri-dina.
ES2035767B1 (es) * 1991-04-05 1994-02-01 Genesis Para La Investigacion Procedimiento de obtencion de 2-hidroximetil-3,5-dimetilpiridinas 4-sustituidas.
DE4411657A1 (de) * 1994-04-02 1995-10-05 Basf Ag Verfahren zur Herstellung von 6-Hydroxymethylchinolinen
ES2097089B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Procedimiento para la preparacion de 2-hidroximetil-3,5-dimetil-4-metoxipiridina.
US5616713A (en) * 1996-07-22 1997-04-01 Development Center For Biotechnology Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine
US5625069A (en) * 1996-07-22 1997-04-29 Development Center For Biotechnology Process for preparing 2-cyano-3,5-dimethyl-4-methoxypyridine
CA2204580A1 (en) * 1997-05-06 1998-11-06 Michel Zoghbi Synthesis of pharmaceutically useful pyridine derivatives
US6437139B1 (en) 1997-05-06 2002-08-20 Pdi-Research Laboratories, Inc. Synthesis of pharmaceutically useful pyridine derivatives
GB0025616D0 (en) * 2000-10-19 2000-12-06 Aventis Cropscience Sa Novel process
KR100818566B1 (ko) * 2000-08-25 2008-04-01 바이엘 크롭사이언스 소시에떼아노님 2-아미노에틸피리딘의 제조 방법
EP1746089B1 (de) * 2000-08-25 2015-06-17 Bayer CropScience S.A. Verfahren zur herstellung von 2-cyanopyridin-derivaten
EP1422221A1 (de) * 2002-11-20 2004-05-26 Bayer CropScience SA Verfahren zur Herstellung von 2-Aminomethylpyridin-Derivaten
EA200900985A1 (ru) 2007-01-31 2009-12-30 Крка, Товарна Здравил, Д. Д., Ново Место Способ получения оптически чистого омепразола
CN101648907B (zh) * 2009-09-14 2011-08-03 南京第一农药集团有限公司 2-氯甲基-4-甲氧基-3,5-二甲基吡啶盐酸盐的纯化方法
CN101648912B (zh) * 2009-09-14 2012-07-04 南京第一农药集团有限公司 一种4-硝基-3,5-二甲基吡啶-n-氧化物的连续化制备方法
CN102603620B (zh) * 2012-01-13 2014-10-29 江苏中邦制药有限公司 一种氯甲基吡啶或其吡啶衍生物盐酸盐的合成方法
WO2014091450A1 (en) * 2012-12-12 2014-06-19 Ranbaxy Laboratories Limited Process for the preparation of rabeprazole
CN114805193B (zh) * 2022-04-19 2023-06-20 南京红太阳医药研究院有限公司 一种奥美拉唑中间体的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3829429A (en) * 1970-01-07 1974-08-13 Du Pont Catalytic synthesis of substituted pyridines from acetylenes and nitriles
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4159382A (en) * 1978-06-28 1979-06-26 The Dow Chemical Company Process for preparing picolylamine
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
SE8204879D0 (sv) * 1982-08-26 1982-08-26 Haessle Ab Novel chemical intermediates
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
IL71665A (en) * 1983-05-03 1988-05-31 Byk Gulden Lomberg Chem Fab Fluoro-(2-pyridyl-methylthio)-dioxolo-(and dioxino-)benzimidazoles,processes for their preparation and pharmaceutical compositions containing the same
DE3415971A1 (de) * 1983-05-03 1984-11-08 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Acylierte benzimidazole, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel
IL71664A (en) * 1983-05-03 1987-11-30 Byk Gulden Lomberg Chem Fab Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
CN85103357A (zh) * 1985-05-13 1986-11-12 霍夫曼·拉罗奇有限公司 三环咪唑衍生物及其酸加成盐的制法
SE8504409D0 (sv) * 1985-09-24 1985-09-24 Haessle Ab Novel chemical intermediates
CA1276017C (en) * 1986-02-13 1990-11-06 Takeda Chemical Industries, Ltd. Sulfenamide derivatives and their production
JPH0717631B2 (ja) * 1986-03-04 1995-03-01 武田薬品工業株式会社 ピリジニウム誘導体およびその製造法
US4739057A (en) * 1986-06-30 1988-04-19 Stauffer Chemical Co. Process for converting organo-hydroxyl compounds to halides
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
DE3837411A1 (de) * 1987-11-13 1989-06-01 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer

Also Published As

Publication number Publication date
PT92307B (pt) 1995-07-18
JPH02180868A (ja) 1990-07-13
NZ231252A (en) 1991-05-28
HUT52480A (en) 1990-07-28
DE3840372A1 (de) 1990-05-31
ATE86978T1 (de) 1993-04-15
NO894410L (no) 1990-05-16
ZA898273B (en) 1990-07-25
KR900007803A (ko) 1990-06-02
EP0369208A1 (de) 1990-05-23
US5066810A (en) 1991-11-19
CN1042705A (zh) 1990-06-06
DD284877A5 (de) 1990-11-28
FI895389A0 (fi) 1989-11-13
YU216389A (en) 1991-02-28
PH25813A (en) 1991-11-05
CA2002757A1 (en) 1990-05-15
AU4465789A (en) 1990-05-24
NO894410D0 (no) 1989-11-06
IL92152A0 (en) 1990-07-12
AT391693B (de) 1990-11-12
ES2053906T3 (es) 1994-08-01
CS276357B6 (en) 1992-05-13
PT92307A (pt) 1990-05-31
HU207995B (en) 1993-07-28
EP0369208B1 (de) 1993-03-17
CS643889A3 (en) 1992-01-15
HU895899D0 (en) 1990-02-28
SU1745121A3 (ru) 1992-06-30
DK568989A (da) 1990-05-16
DK568989D0 (da) 1989-11-14
ATA278988A (de) 1990-05-15
IL92152A (en) 1993-05-13
GR3007391T3 (de) 1993-07-30
AU628100B2 (en) 1992-09-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee