DE59205688D1 - Stabile pulverförmige Vitamin- und/oder Carotinoid-Präparate und Verfahren zu deren Herstellung - Google Patents

Stabile pulverförmige Vitamin- und/oder Carotinoid-Präparate und Verfahren zu deren Herstellung

Info

Publication number
DE59205688D1
DE59205688D1 DE59205688T DE59205688T DE59205688D1 DE 59205688 D1 DE59205688 D1 DE 59205688D1 DE 59205688 T DE59205688 T DE 59205688T DE 59205688 T DE59205688 T DE 59205688T DE 59205688 D1 DE59205688 D1 DE 59205688D1
Authority
DE
Germany
Prior art keywords
preparation
powdered vitamin
stable powdered
carotenoid preparations
carotenoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59205688T
Other languages
English (en)
Inventor
Joachim U Dr Schneider
Horst Dr Schumacher
Wolfgang Dr Bewert
Guenter Dr Gaus
Udo Dr Rheude
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to DE59205688T priority Critical patent/DE59205688D1/de
Application granted granted Critical
Publication of DE59205688D1 publication Critical patent/DE59205688D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE59205688T 1991-12-14 1992-12-01 Stabile pulverförmige Vitamin- und/oder Carotinoid-Präparate und Verfahren zu deren Herstellung Expired - Lifetime DE59205688D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59205688T DE59205688D1 (de) 1991-12-14 1992-12-01 Stabile pulverförmige Vitamin- und/oder Carotinoid-Präparate und Verfahren zu deren Herstellung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4141351A DE4141351A1 (de) 1991-12-14 1991-12-14 Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung
DE59205688T DE59205688D1 (de) 1991-12-14 1992-12-01 Stabile pulverförmige Vitamin- und/oder Carotinoid-Präparate und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
DE59205688D1 true DE59205688D1 (de) 1996-04-18

Family

ID=6447112

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4141351A Withdrawn DE4141351A1 (de) 1991-12-14 1991-12-14 Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung
DE59205688T Expired - Lifetime DE59205688D1 (de) 1991-12-14 1992-12-01 Stabile pulverförmige Vitamin- und/oder Carotinoid-Präparate und Verfahren zu deren Herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4141351A Withdrawn DE4141351A1 (de) 1991-12-14 1991-12-14 Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung

Country Status (7)

Country Link
US (1) US5356636A (de)
EP (1) EP0547422B1 (de)
JP (1) JP2519008B2 (de)
CA (1) CA2083754C (de)
DE (2) DE4141351A1 (de)
DK (1) DK0547422T3 (de)
IL (1) IL103866A (de)

Families Citing this family (82)

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DE4405545A1 (de) * 1994-02-22 1995-08-31 Dietl Hans Fettlösliche Vitamine enthaltende Zubereitung zur oralen Applikation
DE19539574A1 (de) 1995-10-25 1997-04-30 Boehringer Mannheim Gmbh Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
JPH09124470A (ja) 1995-10-26 1997-05-13 Suntory Ltd 抗ストレス組成物
US5747544A (en) * 1995-10-31 1998-05-05 Applied Food Biotechnology, Inc. Method of using pure 3R-3'R stereoisomer of zeaxanthin to treat or prevent retinal degeneration in humans
US5854015A (en) * 1995-10-31 1998-12-29 Applied Food Biotechnology, Inc. Method of making pure 3R-3'R stereoisomer of zeaxanthin for human ingestion
US5827652A (en) 1995-10-31 1998-10-27 Applied Food Biotechnology, Inc. Zeaxanthin formulations for human ingestion
CA2188983C (en) 1995-10-31 2001-02-27 Kevin M. Garnett Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humans
US5948443A (en) * 1996-02-23 1999-09-07 Medical Doctor's Research Institute, Inc. Acetylsalicylic acid and micronutrient supplementation for nutritional losses and coronary heart disease
JP3555640B2 (ja) * 1996-05-10 2004-08-18 ライオン株式会社 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤
GB9616910D0 (en) * 1996-08-12 1996-09-25 Dunnett Mark A method of increasing ›-alanylihistidine pipetide synthesis and accumulation in humans and animals
DE19637517A1 (de) * 1996-09-13 1998-03-19 Basf Ag Herstellung von pulverförmigen, kaltwasserdispergierbaren Carotinoid-Zubereitungen und die Verwendung der neuen Carotinoid-Zubereitungen
DE19642359A1 (de) * 1996-10-14 1998-04-16 Basf Ag Stabile Emulsionen und Trockenpulver von Mischungen fettlöslicher Vitamine, deren Herstellung und Verwendung
DE19649062A1 (de) * 1996-11-27 1998-05-28 Basf Ag Flüssige, mit Öl mischbare Carotinoid-Zubereitungen
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
DE19703469C2 (de) * 1997-01-31 2003-10-30 Wolfgang Von Rhein Verfahren zur Herstellung eines oxidationsgeschützten Vitamin-C-Präparats
US5976568A (en) * 1997-02-21 1999-11-02 Medical Doctors' Research Institute, Inc. Modular system of dietary supplement compositions for optimizing health benefits and methods
US6007856A (en) * 1997-08-08 1999-12-28 The Procter & Gamble Company Oil-in-water dispersions of β-carotene and other carotenoids stable against oxidation prepared from water-dispersible beadlets having high concentrations of carotenoid
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EP0913177A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics GmbH Verfahren zur Herstellung trockener, amorpher Produkte enthaltend biologisch aktive Materialien mittels Konvektionstrocknung, insbesondere Sprühtrocknung
JP4027535B2 (ja) * 1998-05-26 2007-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂溶性薬物を含有した粉末
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US6146671A (en) * 1999-05-08 2000-11-14 Kemin Industries, Inc. Method and protecting heat-or oxygen-labile compounds to preserve activity and bioavailability
EP1066761B1 (de) * 1999-07-06 2004-09-29 DSM IP Assets B.V. Zusammensetzung, die fettlösliche Substanzen in einer Kohlenhydratmatrix enthält
US6582721B1 (en) 1999-09-17 2003-06-24 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
US6328995B1 (en) * 1999-09-24 2001-12-11 Basf Aktiengesellschaft Stable vitamin and/or carotenoid products in powder form and process for their production
US6989161B2 (en) 2000-06-12 2006-01-24 Access Business Group International Llc Phytonutrient nutritional supplement
US7416749B2 (en) * 2000-06-12 2008-08-26 Access Business Group International Llc Dietary supplement and related method
US7438936B2 (en) * 2000-06-12 2008-10-21 Access Business Group International Llc Dietary supplement and related method
US7939115B2 (en) * 2000-06-12 2011-05-10 Access Business Group International Llc Dietary supplement and related method
US6511675B2 (en) 2000-06-12 2003-01-28 Access Business Group International, Llc Composition and method for correcting a dietary phytochemical deficiency
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US7691406B2 (en) * 2000-10-27 2010-04-06 ZeaVision LLC. Zeaxanthin formulations for human ingestion
DE10064387A1 (de) * 2000-12-21 2002-06-27 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Sauerstoff-haltiger Carotinoide
US7595378B2 (en) 2001-06-13 2009-09-29 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
ES2238602T3 (es) * 2001-08-23 2005-09-01 Dsm Ip Assets B.V. Nuevas composiciones carotenoides estabilizadas.
US6663900B2 (en) * 2002-02-01 2003-12-16 Kemin Foods, Lc Microcapsules having high carotenoid content
US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
US6936279B2 (en) * 2002-06-18 2005-08-30 Zeavision Llc Microcrystalline zeaxanthin with high bioavailability in oily carrier formulations
US7794764B2 (en) * 2002-10-15 2010-09-14 Mars Incorporated Preservation of process sensitive ingredients in an energy food product by product partitioning
DE60329971D1 (de) * 2002-07-08 2009-12-24 Mars Inc Energieriegel mit verbessertem geschmack
JPWO2004037293A1 (ja) * 2002-10-22 2006-02-23 大日本住友製薬株式会社 安定化組成物
US8088363B2 (en) 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
ES2347045T3 (es) * 2002-11-04 2010-10-25 Ocean Nutrition Canada Limited Microcapsulas que tienen multiples cortezas, y metodo para su preparacion.
US9192586B2 (en) 2003-03-10 2015-11-24 Zeavision Llc Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders
EP1433387A1 (de) * 2002-12-26 2004-06-30 Adisseo France S.A.S. Weichen Kügelchen enthaltend Carotenoide
ES2728781T3 (es) 2003-01-31 2019-10-28 Dsm Ip Assets Bv Nuevas composiciones que comprenden carotenoides
CN1764439B (zh) * 2003-03-27 2010-05-26 帝斯曼知识产权资产管理有限公司 制备交联明胶珠粒的方法
DE602004025212D1 (de) * 2003-04-03 2010-03-11 Dsm Ip Assets Bv Pulverförmige zusammensetzungen von fettlöslichen substanzen
US20070082066A1 (en) * 2003-05-07 2007-04-12 Gierhart Dennis L Use of zeaxanthin to reduce light hyper-sensitivity, photophobia, and medical conditions relating to light hyper-sensitivity
JP5027504B2 (ja) * 2003-07-15 2012-09-19 ディーエスエム アイピー アセッツ ビー．ブイ． 脂溶性活性成分の粉末状製剤
TW200506036A (en) * 2003-08-08 2005-02-16 Showa Denko Kk Production method of substrate with black film and substrate with black film
US7541166B2 (en) * 2003-09-19 2009-06-02 Microfluidic Systems, Inc. Sonication to selectively lyse different cell types
US7941211B2 (en) * 2003-11-17 2011-05-10 Zeavision, Llc. Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders
DE102004006106A1 (de) * 2004-02-06 2005-08-25 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Carotinolde
US20050186307A1 (en) * 2004-02-20 2005-08-25 Axelrod Glen S. Pet food with enhanced nutritional value
CN1929751B (zh) * 2004-03-18 2011-06-22 帝斯曼知识产权资产管理有限公司 在挤出过程中稳定的食物产品用多不饱和脂肪酸组合物
DK1616556T3 (da) * 2004-07-09 2008-07-28 Mavi Sud S R L Formulering på basis af gelatine-glycin og carotinoider
US20060089411A1 (en) * 2004-08-07 2006-04-27 Gierhart Dennis L Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin
US8034450B2 (en) * 2005-01-21 2011-10-11 Ocean Nutrition Canada Limited Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
WO2006117675A1 (en) * 2005-01-27 2006-11-09 Ocean Nutrition Canada Ltd. Fatty acid-benzenediol derivatives and methods of making and using thereof
US20080206316A1 (en) * 2005-01-27 2008-08-28 Colin Barrow Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof
US8592662B2 (en) 2005-02-11 2013-11-26 Kalamazoo Holdings, Inc. Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
US20060185034A1 (en) * 2005-02-11 2006-08-17 Kalamazoo Holdings, Inc. Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
CA2851079A1 (en) * 2005-04-15 2006-10-26 Albert Einstein College Of Medicine Of Yeshiva University Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
KR20090029699A (ko) * 2006-04-07 2009-03-23 오션 뉴트리션 캐나다 리미티드 낮은 계면장력 물질을 가지는 에멀젼 및 마이크로캡슐, 제조방법 및 이용방법
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CA2689590C (en) * 2007-06-19 2017-06-06 Martek Biosciences Corporation Microencapsulating compositions, methods of making, methods of using and products thereof
PL2164975T3 (pl) 2007-07-06 2012-07-31 Basf Se Sposób produkcji stężonego wodnego roztworu glukozy z kukurydzy
US8815953B2 (en) * 2008-03-13 2014-08-26 Spectrum Pharmaceuticals, Inc. Formulations of vitamin K analogs for topical use
CN101971917A (zh) * 2010-08-14 2011-02-16 格特生物制药（天津）有限公司 一种畜禽用脂溶性维生素功能性饲料添加剂及其制备方法
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CN103284290B (zh) * 2013-05-24 2015-04-08 肇庆巨元生化有限公司 一种良好的类胡萝卜素的微囊化方法
CN103315370B (zh) * 2013-05-24 2015-04-08 肇庆巨元生化有限公司 一种稳定的类胡萝卜素的微囊化方法
EP3856386A1 (de) * 2018-09-28 2021-08-04 Dow Global Technologies LLC Alkyletheraminschaumkontrollverbindungen und verfahren zur verarbeitung von lebensmitteln
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DE3307095A1 (de) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt Mikrobiologisch hergestellte l-phenylalanin-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
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Also Published As

Publication number Publication date
JPH0665062A (ja) 1994-03-08
CA2083754A1 (en) 1993-06-15
JP2519008B2 (ja) 1996-07-31
DK0547422T3 (da) 1996-04-01
CA2083754C (en) 2001-08-14
EP0547422A3 (en) 1994-05-11
IL103866A0 (en) 1993-04-04
EP0547422A2 (de) 1993-06-23
US5356636A (en) 1994-10-18
IL103866A (en) 1996-12-05
EP0547422B1 (de) 1996-03-13
DE4141351A1 (de) 1993-06-17

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Owner name: BASF SE, 67063 LUDWIGSHAFEN, DE