DE59403576D1 - Verfahren und träger für die gelpermeationschromotographie - Google Patents

Verfahren und träger für die gelpermeationschromotographie

Info

Publication number
DE59403576D1
DE59403576D1 DE59403576T DE59403576T DE59403576D1 DE 59403576 D1 DE59403576 D1 DE 59403576D1 DE 59403576 T DE59403576 T DE 59403576T DE 59403576 T DE59403576 T DE 59403576T DE 59403576 D1 DE59403576 D1 DE 59403576D1
Authority
DE
Germany
Prior art keywords
pct
polymers
support
sec
covalently bonded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE59403576T
Other languages
English (en)
Inventor
Egbert Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to DE59403576T priority Critical patent/DE59403576D1/de
Application granted granted Critical
Publication of DE59403576D1 publication Critical patent/DE59403576D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28047—Gels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/64—In a syringe, pipette, e.g. tip or in a tube, e.g. test-tube or u-shape tube
DE59403576T 1993-10-08 1994-09-24 Verfahren und träger für die gelpermeationschromotographie Expired - Fee Related DE59403576D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59403576T DE59403576D1 (de) 1993-10-08 1994-09-24 Verfahren und träger für die gelpermeationschromotographie

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4334353A DE4334353A1 (de) 1993-10-08 1993-10-08 Verfahren und Träger für die Gelpermeationschromatographie
PCT/EP1994/003197 WO1995010355A1 (de) 1993-10-08 1994-09-24 Verfahren und träger für die gelpermeationschromotographie
DE59403576T DE59403576D1 (de) 1993-10-08 1994-09-24 Verfahren und träger für die gelpermeationschromotographie

Publications (1)

Publication Number Publication Date
DE59403576D1 true DE59403576D1 (de) 1997-09-04

Family

ID=6499718

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4334353A Withdrawn DE4334353A1 (de) 1993-10-08 1993-10-08 Verfahren und Träger für die Gelpermeationschromatographie
DE59403576T Expired - Fee Related DE59403576D1 (de) 1993-10-08 1994-09-24 Verfahren und träger für die gelpermeationschromotographie

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4334353A Withdrawn DE4334353A1 (de) 1993-10-08 1993-10-08 Verfahren und Träger für die Gelpermeationschromatographie

Country Status (6)

Country Link
US (1) US5667692A (de)
EP (1) EP0722362B1 (de)
JP (1) JP3583782B2 (de)
AT (1) ATE156035T1 (de)
DE (2) DE4334353A1 (de)
WO (1) WO1995010355A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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US6689715B1 (en) * 2000-02-09 2004-02-10 Hammen Corporation Tethered polymer ligands
US6987079B2 (en) * 2001-08-14 2006-01-17 W.R. Grace & Co.-Conn. Supported catalyst systems
US6802966B2 (en) * 2001-08-14 2004-10-12 W. R. Grace & Co. Conn. Solid compositions for selective adsorption from complex mixtures
US6375846B1 (en) * 2001-11-01 2002-04-23 Harry Wellington Jarrett Cyanogen bromide-activation of hydroxyls on silica for high pressure affinity chromatography
US7747095B2 (en) 2004-10-08 2010-06-29 Nvidia Corporation Methods and systems for rate control in image compression
EP2291481B1 (de) * 2008-05-30 2014-10-01 3M Innovative Properties Company Klebende zusammensetzungen mit mehreren klebrigmachern
US20090294362A1 (en) * 2008-05-30 2009-12-03 Persson Jonas Par Stationary phase for hydrophilic interaction chromatography
WO2009158071A2 (en) * 2008-06-26 2009-12-30 3M Innovative Properties Company Solid support with a grafted chain
CN102365262B (zh) * 2009-03-31 2014-09-17 3M创新有限公司 疏水单体、疏水衍生载体及其制备和使用方法
JP5703514B2 (ja) * 2010-11-02 2015-04-22 日立化成株式会社 金の捕集材および分離回収方法
KR102118146B1 (ko) * 2019-09-17 2020-06-02 안전성평가솔루션 주식회사 고분자화합물 법령 검토 장치 및 그 방법

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SE366760B (de) * 1967-12-18 1974-05-06 J Sjoevall
US3663263A (en) * 1969-04-03 1972-05-16 Monsanto Co Method of preparing chromatographic columns
US3808125A (en) * 1972-08-25 1974-04-30 Phillips Petroleum Co Chromatographic apparatus
JPS5247355B2 (de) * 1974-10-15 1977-12-01
US4029583A (en) * 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
US4140653A (en) * 1975-09-30 1979-02-20 Toyo Soda Manufacturing Co., Ltd. Solid support for liquid chromatography
CH641689A5 (en) * 1976-10-28 1984-03-15 Asahi Chemical Ind Process for preparing a protein adsorbent
SE7712058L (sv) * 1976-11-12 1978-05-13 Ceskoslovenska Akademie Ved Tredimensionell berare av oorganiskt, porost material och en reaktiv polymer och ett forfarande for framstellning derav
US4330440A (en) * 1977-02-08 1982-05-18 Development Finance Corporation Of New Zealand Activated matrix and method of activation
DE2709094C2 (de) * 1977-03-02 1984-11-22 Boehringer Mannheim Gmbh, 6800 Mannheim Adsorbens für die affinitätsspezifische Trennung von Nukleinsäuren, Verfahren zu seiner Herstellung und seine Verwendung
DE2827109C2 (de) * 1977-06-24 1986-10-30 Asahi Kasei Kogyo K.K., Osaka Verfahren und Vorrichtung zur Abtrennung von organischen Verbindungen von Plasmaproteinen des Blutes
JPS54160300A (en) * 1978-06-08 1979-12-18 Toyo Soda Mfg Co Ltd Hydrophilic separating carrier and making method thereof
US4406870A (en) * 1979-12-27 1983-09-27 Asahi Kasei Kogyo Kabushiki Kaisha Method for the separation of carbon isotopes by chemical exchange method
JPS56115727A (en) * 1980-02-19 1981-09-11 Kuraray Co Ltd Carrier for immobilizing physiologically active substance
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EP0043159B1 (de) * 1980-06-27 1985-09-04 Akzo N.V. Mit einer unbeweglichen organischen Phase überzogenes anorganisches poröses Trägermaterial, Anwendung für die Chromatographie und sein Herstellungsverfahren
DE3116995A1 (de) * 1981-04-29 1982-11-25 Röhm GmbH, 6100 Darmstadt Latex zur immobilisierung von biologisch wirksamen substanzen
DE3407814A1 (de) * 1984-03-02 1985-09-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Phasentraeger fuer die verteilungschromatographie von makromolekuelen, verfahren zu ihrer herstellung und ihre verwendung
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Also Published As

Publication number Publication date
WO1995010355A1 (de) 1995-04-20
ATE156035T1 (de) 1997-08-15
US5667692A (en) 1997-09-16
JPH09503865A (ja) 1997-04-15
JP3583782B2 (ja) 2004-11-04
EP0722362B1 (de) 1997-07-30
EP0722362A1 (de) 1996-07-24
DE4334353A1 (de) 1995-04-13

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee