DE59609923D1 - Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze - Google Patents

Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Info

Publication number: DE59609923D1
Authority: DE; Germany
Prior art keywords: extrusion; polymer; available; active substance; solid pharmaceutical
Prior art date: 1995-09-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE59609923T

Other languages

English (en)

Inventor

Juergen Zeidler

Joerg Rosenberg

Joerg Neumann

Joerg Breitenbach

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

BASF SE

Original Assignee

BASF SE

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-29

Filing date

1996-09-30

Publication date

2003-01-09

1996-09-30 Application filed by BASF SE filed Critical BASF SE

1996-09-30 Priority to DE59609923T priority Critical patent/DE59609923D1/de

2003-01-09 Application granted granted Critical

2003-01-09 Publication of DE59609923D1 publication Critical patent/DE59609923D1/de

2016-10-01 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 title abstract 2
238000001125 extrusion Methods 0.000 title abstract 2
235000010439 isomalt Nutrition 0.000 title abstract 2
239000000905 isomalt Substances 0.000 title abstract 2
HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 title abstract 2
239000007787 solid Substances 0.000 title abstract 2
239000013543 active substance Substances 0.000 title 1
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
101100379081 Emericella variicolor andC gene Proteins 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
229940067606 lecithin Drugs 0.000 abstract 1
235000010445 lecithin Nutrition 0.000 abstract 1
239000000787 lecithin Substances 0.000 abstract 1
238000007493 shaping process Methods 0.000 abstract 1
229920003169 water-soluble polymer Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

DE59609923T 1995-09-29 1996-09-30 Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze Expired - Lifetime DE59609923D1 (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DE59609923T DE59609923D1 (de)	1995-09-29	1996-09-30	Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19536394A DE19536394A1 (de)	1995-09-29	1995-09-29	Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
PCT/EP1996/004262 WO1997012603A1 (de)	1995-09-29	1996-09-30	Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze
DE59609923T DE59609923D1 (de)	1995-09-29	1996-09-30	Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Publications (1)

Publication Number	Publication Date
DE59609923D1 true DE59609923D1 (de)	2003-01-09

Family

ID=7773633

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE19536394A Withdrawn DE19536394A1 (de)	1995-09-29	1995-09-29	Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
DE59609923T Expired - Lifetime DE59609923D1 (de)	1995-09-29	1996-09-30	Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DE19536394A Withdrawn DE19536394A1 (de)	1995-09-29	1995-09-29	Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze

Country Status (22)

Country	Link
US (1)	US6187342B1 (de)
EP (1)	EP0854707B1 (de)
JP (1)	JP4041163B2 (de)
KR (1)	KR19990063853A (de)
CN (1)	CN1200694C (de)
AT (1)	ATE228355T1 (de)
AU (1)	AU7282896A (de)
BG (1)	BG102346A (de)
BR (1)	BR9610799A (de)
CA (1)	CA2230950C (de)
CZ (1)	CZ95998A3 (de)
DE (2)	DE19536394A1 (de)
DK (1)	DK0854707T3 (de)
ES (1)	ES2187678T3 (de)
HU (1)	HUP9903384A3 (de)
IL (1)	IL123250A (de)
MX (1)	MX9801988A (de)
NO (1)	NO981394D0 (de)
RU (1)	RU2197228C2 (de)
TW (1)	TW438599B (de)
WO (1)	WO1997012603A1 (de)
ZA (1)	ZA968130B (de)

Families Citing this family (37)

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DE19809242A1 (de) *	1998-03-05	1999-09-09	Basf Ag	Verfahren zur Herstellung von festen, sphärischen Formkörpern, enthaltend pharmazeutische Wirkstoffe in einer Bindemittelmatrix
US6465009B1 (en)	1998-03-18	2002-10-15	Yamanouchi Pharmaceutical Co., Ltd.	Water soluble polymer-based rapidly dissolving tablets and production processes thereof
US7364752B1 (en)	1999-11-12	2008-04-29	Abbott Laboratories	Solid dispersion pharamaceutical formulations
JP5767429B2 (ja) *	1999-11-12	2015-08-19	アッヴィ・インコーポレイテッド	固体分散剤中の結晶化阻害剤
US20070141107A1 (en) *	2000-03-15	2007-06-21	Orbusneich Medical, Inc.	Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US9522217B2 (en)	2000-03-15	2016-12-20	Orbusneich Medical, Inc.	Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) *	2000-03-15	2012-01-03	Orbusneich Medical, Inc.	Progenitor endothelial cell capturing with a drug eluting implantable medical device
DE10026698A1 (de) *	2000-05-30	2001-12-06	Basf Ag	Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US7067148B2 (en) *	2001-02-15	2006-06-27	King Pharmaceutical Research & Development, Inc.	Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US20030224047A1 (en) *	2001-02-15	2003-12-04	Franz G. Andrew	Levothyroxine compositions and methods
US6555581B1 (en)	2001-02-15	2003-04-29	Jones Pharma, Inc.	Levothyroxine compositions and methods
US20030032675A1 (en) *	2001-02-15	2003-02-13	Franz G. Andrew	Manufacture of thyroid hormone tablets having consistent active moiety amounts
AR033444A1 (es) *	2001-03-26	2003-12-17	Smithkline Beecham Corp	Forma solida de dosificacion util para la administracion oral de un compuesto activo de nicotina, a traves de la mucosa y uso de un compuesto activo de nicotina para prepararla
FR2823974B1 (fr) *	2001-04-25	2004-10-15	Pf Medicament	Pastille medicamenteuse a liberation lente du principe actif
US20030198671A1 (en) *	2001-08-10	2003-10-23	Franz G. Andrew	Levothyroxine compositions having unique plasma AUC properties
US20030198667A1 (en) *	2001-08-10	2003-10-23	Franz Andrew G.	Methods of producing dispersible pharmaceutical compositions
US20030180353A1 (en) *	2001-08-10	2003-09-25	Franz G. Andrew	Stabilized pharmaceutical compositions
US20030190349A1 (en) *	2001-08-10	2003-10-09	Franz G. Andrew	Methods of stabilizing pharmaceutical compositions
US20030199587A1 (en) *	2001-08-14	2003-10-23	Franz G. Andrew	Levothyroxine compositions having unique Cmax properties
US20030199586A1 (en) *	2001-08-14	2003-10-23	Franz G. Andrew	Unique levothyroxine aqueous materials
US20030195253A1 (en) *	2001-08-14	2003-10-16	Franz G. Andrew	Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030198672A1 (en) *	2001-08-14	2003-10-23	Franz G. Andrew	Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030203967A1 (en) *	2001-08-14	2003-10-30	Franz G. Andrew	Levothyroxine compositions having unique Tmax properties
US20040043066A1 (en) *	2001-10-29	2004-03-04	Franz G. Andrew	Levothyroxine compositions having unique triiodothyronine Tmax properties
KR100514590B1 (ko) *	2001-12-18	2005-09-14	주식회사 대웅	프라바스타틴나트륨 및 안정화제로서의 코폴리비돈을함유하는 약제 조성물
US20040101543A1 (en) *	2002-03-22	2004-05-27	John Liu	Nicotine-containing oral dosage form
ATE359777T1 (de) *	2002-12-17	2007-05-15	Abbott Gmbh & Co Kg	Fenofibratsäure enthaltende pharmazeutische zusammensetzung und deren physiologisch verträgliche salze und derivate
US20080051411A1 (en) *	2002-12-17	2008-02-28	Cink Russell D	Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
CA2509958A1 (en) *	2003-02-03	2004-08-19	Novartis Ag	Pharmaceutical formulation
US8025899B2 (en)	2003-08-28	2011-09-27	Abbott Laboratories	Solid pharmaceutical dosage form
US8377952B2 (en) *	2003-08-28	2013-02-19	Abbott Laboratories	Solid pharmaceutical dosage formulation
GB2418854B (en) *	2004-08-31	2009-12-23	Euro Celtique Sa	Multiparticulates
EP2140861A1 (de) *	2008-06-30	2010-01-06	Abbott GmbH & Co. KG	Pharmazeutische Dosierungsform mit polymerischer Trägerzusammensetzung
SG189403A1 (en) *	2010-10-14	2013-05-31	Abbott Gmbh & Co Kg	Curcuminoid solid dispersion formulation
BR112013023879B1 (pt)	2011-03-21	2022-08-30	Boehringer Ingelheim International Gmbh	Preparações sólidas que contém ambroxol, seu método de preparação, forma de dosagem farmacêutica e seus usos
US9375033B2 (en)	2014-02-14	2016-06-28	R.J. Reynolds Tobacco Company	Tobacco-containing gel composition
JPWO2017175792A1 (ja) *	2016-04-06	2019-02-14	アステラス製薬株式会社	速溶出性三次元造形物、速溶出性三次元造形物用フィラメント及び速溶出性三次元造形物用材料

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3612211A1 (de)	1986-04-11	1987-10-15	Basf Ag	Kontinuierliches verfahren zum tablettieren
DE3826946C1 (de) *	1988-08-09	1990-03-15	A. Nattermann & Cie Gmbh, 5000 Koeln, De
BR9508034A (pt)	1994-06-14	1997-09-16	Fuisz Technologies Ltd	Processo e aparelhagem para a preparação de uma unidade comestível que se dissolve rapidamente a referida unidade composição para liberar um ingrediente ativo processo para administração de um ingrediente ativo a um hospedeiro humano e produto provisório para fabricação da unidade comestível

1995
- 1995-09-29 DE DE19536394A patent/DE19536394A1/de not_active Withdrawn
1996
- 1996-09-26 TW TW085111773A patent/TW438599B/zh not_active IP Right Cessation
- 1996-09-27 ZA ZA9608130A patent/ZA968130B/xx unknown
- 1996-09-30 IL IL12325096A patent/IL123250A/xx not_active IP Right Cessation
- 1996-09-30 HU HU9903384A patent/HUP9903384A3/hu unknown
- 1996-09-30 JP JP51396597A patent/JP4041163B2/ja not_active Expired - Lifetime
- 1996-09-30 US US09/029,362 patent/US6187342B1/en not_active Expired - Lifetime
- 1996-09-30 WO PCT/EP1996/004262 patent/WO1997012603A1/de not_active Application Discontinuation
- 1996-09-30 DE DE59609923T patent/DE59609923D1/de not_active Expired - Lifetime
- 1996-09-30 CN CNB961972637A patent/CN1200694C/zh not_active Expired - Lifetime
- 1996-09-30 RU RU98108536/14A patent/RU2197228C2/ru active
- 1996-09-30 DK DK96934494T patent/DK0854707T3/da active
- 1996-09-30 KR KR1019980702324A patent/KR19990063853A/ko not_active Application Discontinuation
- 1996-09-30 AU AU72828/96A patent/AU7282896A/en not_active Abandoned
- 1996-09-30 EP EP96934494A patent/EP0854707B1/de not_active Expired - Lifetime
- 1996-09-30 ES ES96934494T patent/ES2187678T3/es not_active Expired - Lifetime
- 1996-09-30 CA CA002230950A patent/CA2230950C/en not_active Expired - Lifetime
- 1996-09-30 BR BR9610799A patent/BR9610799A/pt active Search and Examination
- 1996-09-30 AT AT96934494T patent/ATE228355T1/de active
- 1996-09-30 CZ CZ98959A patent/CZ95998A3/cs unknown
1998
- 1998-03-13 MX MX9801988A patent/MX9801988A/es not_active IP Right Cessation
- 1998-03-24 BG BG102346A patent/BG102346A/bg unknown
- 1998-03-27 NO NO981394A patent/NO981394D0/no unknown

Also Published As

Publication number	Publication date
BR9610799A (pt)	1999-07-13
NO981394L (no)	1998-03-27
NO981394D0 (no)	1998-03-27
WO1997012603A1 (de)	1997-04-10
HUP9903384A3 (en)	2001-04-28
EP0854707B1 (de)	2002-11-27
JP4041163B2 (ja)	2008-01-30
US6187342B1 (en)	2001-02-13
ATE228355T1 (de)	2002-12-15
KR19990063853A (ko)	1999-07-26
HUP9903384A2 (hu)	2000-10-28
CA2230950C (en)	2007-12-04
CN1198094A (zh)	1998-11-04
ZA968130B (en)	1998-03-27
MX9801988A (es)	1998-08-30
IL123250A0 (en)	1998-09-24
EP0854707A1 (de)	1998-07-29
DE19536394A1 (de)	1997-04-03
CZ95998A3 (cs)	1998-08-12
BG102346A (bg)	1998-10-30
ES2187678T3 (es)	2003-06-16
CA2230950A1 (en)	1997-04-10
CN1200694C (zh)	2005-05-11
IL123250A (en)	2000-08-31
RU2197228C2 (ru)	2003-01-27
AU7282896A (en)	1997-04-28
TW438599B (en)	2001-06-07
DK0854707T3 (da)	2002-12-16
JPH11512729A (ja)	1999-11-02

Legal Events

Date	Code	Title	Description
2008-05-29	8327	Change in the person/name/address of the patent owner	Owner name: BASF SE, 67063 LUDWIGSHAFEN, DE

Publication	Publication Date	Title
DE59609923D1 (de)	2003-01-09	Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze
HUP9801151A2 (hu)	1998-08-28	Stabilan tárolható gyógyszerformák
HUP0104573A2 (hu)	2002-03-28	Agrokémiai készítmények
CA2327723A1 (en)	1999-10-21	Bicyclic hydroxamic acid derivatives
EP1158021A4 (de)	2006-04-12	Mikrogele und diese beinhaltende äusserlich anzuwendende präparate
TR199700786T1 (xx)	1998-02-21	Kat� aktif madde bile�imleri.
CY1110988T1 (el)	2015-06-11	Ταχεως αποσαθρουμενο στερεο παρασκευασμα
AR029546A1 (es)	2003-07-02	Particulas farmaceuticas con sabor enmascarado
BRPI9509286B8 (pt)	2019-12-17	microcápsulas medicamentosas e/ou nutricionais para administração per si.
ATE209898T1 (de)	2001-12-15	Feste arzneizubereitung
NO963673L (no)	1996-09-03	Orale vehikkelblandinger
IE894048L (en)	1990-06-22	New therapeutically active compound and a process for its¹preparation
IL123293A (en)	2003-06-24	Piperidine derivatives, their preparation and pharmaceutical compositions containing them
TR200101499T1 (tr)	2002-09-23	Azepinoindol türevleri, hazırlanmaları ve kullanımları.
FR2686084B1 (fr)	1995-12-22	Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.
CA2420874A1 (en)	2003-02-28	Active ingredient combinations with insecticidal and acaricidal properties
BRPI0417043A (pt)	2007-02-06	composição farmacêutica, forma de dosagem sólida, método de manufatura de forma de dosagem sólida, e, uso da composição
NO974321L (no)	1997-11-19	Nodulisporsyrederivater
CA2343732A1 (en)	2000-03-16	Substituted .gamma.-phenyl-.delta.-lactones and analogs thereof and uses related thereto
HUP0003571A2 (hu)	2001-02-28	6,9-Hídkötésű eritromicin-származékok
DE60030553D1 (de)	2006-10-19	Kosmetische zusammensetzungen
HUP9800573A2 (hu)	1999-06-28	Orálisan beadható rapamicintartalmú készítmények és eljárás előállításukra
EP0146863A3 (de)	1986-10-08	Orale retardierte Acetylsalicylsäureformulierungen
WO2001078682A3 (en)	2002-04-18	Sustained release drug compositions
ITRM910430A1 (it)	1992-12-17	Composizioni farmaceutiche di somatostatina con assorbimento migliorato, loro preparazione e loro impiego