DE60015151D1 - Neue zusammensetzungen zur kontrollierten freigabe eines biologisch wirksamen mittels sowie die herstellung derselben - Google Patents

Neue zusammensetzungen zur kontrollierten freigabe eines biologisch wirksamen mittels sowie die herstellung derselben

Info

Publication number
DE60015151D1
DE60015151D1 DE60015151T DE60015151T DE60015151D1 DE 60015151 D1 DE60015151 D1 DE 60015151D1 DE 60015151 T DE60015151 T DE 60015151T DE 60015151 T DE60015151 T DE 60015151T DE 60015151 D1 DE60015151 D1 DE 60015151D1
Authority
DE
Germany
Prior art keywords
biologically active
active agent
controlled release
production
new compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60015151T
Other languages
English (en)
Other versions
DE60015151T2 (de
Inventor
Manja Ahola
Eija Saeilynoja
Jukka Salonen
Risto Penttinen
Antti Yli-Urpo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioxid Oy
Original Assignee
Bioxid Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioxid Oy filed Critical Bioxid Oy
Application granted granted Critical
Publication of DE60015151D1 publication Critical patent/DE60015151D1/de
Publication of DE60015151T2 publication Critical patent/DE60015151T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
DE60015151T 1999-08-25 2000-08-22 Neue zusammensetzungen zur kontrollierten freigabe eines biologisch wirksamen mittels sowie die herstellung derselben Expired - Fee Related DE60015151T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI991806 1999-08-25
FI991806A FI19991806A (fi) 1999-08-25 1999-08-25 Uusia koostumuksia biologisesti aktiivisen aineen säädettyyn vapauttamiseen, ja niiden valmistus
PCT/FI2000/000710 WO2001013924A1 (en) 1999-08-25 2000-08-22 Novel compositions for controlled release of a biologically active agent, and the preparation thereof

Publications (2)

Publication Number Publication Date
DE60015151D1 true DE60015151D1 (de) 2004-11-25
DE60015151T2 DE60015151T2 (de) 2006-02-16

Family

ID=8555195

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60015151T Expired - Fee Related DE60015151T2 (de) 1999-08-25 2000-08-22 Neue zusammensetzungen zur kontrollierten freigabe eines biologisch wirksamen mittels sowie die herstellung derselben

Country Status (11)

Country Link
US (1) US7112339B1 (de)
EP (1) EP1206268B1 (de)
JP (1) JP2003507427A (de)
AT (1) ATE279928T1 (de)
AU (1) AU6705400A (de)
CA (1) CA2379982A1 (de)
DE (1) DE60015151T2 (de)
DK (1) DK1206268T3 (de)
ES (1) ES2230141T3 (de)
FI (1) FI19991806A (de)
WO (1) WO2001013924A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ573300A0 (en) * 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US7758888B2 (en) 2000-04-21 2010-07-20 Sol-Gel Technologies Ltd. Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
EP1372727B1 (de) 2001-04-04 2010-09-01 DelSiTech Oy Biologisch abbaubarer träger und verfahren zu seiner herstellung
EP1499890B1 (de) * 2002-05-07 2010-04-28 The Research Foundation of State University of New York "High througput" Methode, um Biomolekülanlieferung Formulierungen zu kennzeichnen
DE10249874A1 (de) * 2002-10-25 2004-05-06 Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien e.V. Antiadhäsive Beschichtung zur Ausrüstung von Wundverbänden
WO2004081222A2 (en) 2003-03-14 2004-09-23 Sol-Gel Technologies Ltd. Agent-encapsulating micro- and nanoparticles, methods for preparation of same and products containing same
EP2263788B1 (de) 2003-07-31 2018-07-25 Sol-Gel Technologies Ltd. Eine verfahren zur herstellung von mikrokapseln die aktive stoff enthalten
US10149825B2 (en) * 2004-02-27 2018-12-11 Delsitech Oy Method for preparing adjustably bioresorbable sol-gel derived SiO2
GB0420016D0 (en) 2004-09-09 2004-10-13 Leuven K U Res & Dev Controlled release oral delivery system
JP5164840B2 (ja) 2005-08-02 2013-03-21 ソル − ゲル テクノロジーズ リミテッド 水不溶性成分の金属酸化物被覆
FI20070174A0 (fi) * 2007-02-28 2007-02-28 Delsitech Oy Menetelmä silikakoostumusten valmistamiseksi, silikakoostumukset ja niiden käytöt
US11458105B2 (en) 2008-12-04 2022-10-04 International Flavors & Fragrances Inc. Hybrid fragrance encapsulate formulation and method for using the same
US9763861B2 (en) 2008-12-04 2017-09-19 International Flavors & Fragrances Inc. Stable, flowable silica capsule formulation
KR101070345B1 (ko) 2009-07-03 2011-10-06 서울대학교산학협력단 생체활성인자가 포함된 유무기 혼성 복합 코팅층, 생체 이식용 임플란트 및 그 제조방법
ES2919933T3 (es) * 2011-03-18 2022-07-29 Int Flavors & Fragrances Inc Microcápsulas producidas a partir de precursores de sol-gel combinados y método de producción de las mismas
US9205150B2 (en) 2011-12-05 2015-12-08 Incept, Llc Medical organogel processes and compositions
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804318A (en) * 1995-10-26 1998-09-08 Corvita Corporation Lubricious hydrogel surface modification
JP3488965B2 (ja) * 1996-05-21 2004-01-19 日本山村硝子株式会社 ゾル−ゲル法による独立膜の製造方法
HU227939B1 (en) * 1996-05-29 2012-06-28 Delsitech Oy Dissolvable oxides for biological applications
ATE368011T1 (de) 1999-02-22 2007-08-15 Delsitech Oy Biologisch abbaubaren keramischen fasern aus kiselsäuresol

Also Published As

Publication number Publication date
AU6705400A (en) 2001-03-19
DE60015151T2 (de) 2006-02-16
EP1206268B1 (de) 2004-10-20
ES2230141T3 (es) 2005-05-01
CA2379982A1 (en) 2001-03-01
JP2003507427A (ja) 2003-02-25
EP1206268A1 (de) 2002-05-22
ATE279928T1 (de) 2004-11-15
DK1206268T3 (da) 2005-01-10
FI19991806A (fi) 2001-02-26
WO2001013924A8 (en) 2001-11-01
US7112339B1 (en) 2006-09-26
WO2001013924A1 (en) 2001-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee