DE60020220D1 - Plättchenadhäsion blockierendes protein - Google Patents

Plättchenadhäsion blockierendes protein

Info

Publication number
DE60020220D1
DE60020220D1 DE60020220T DE60020220T DE60020220D1 DE 60020220 D1 DE60020220 D1 DE 60020220D1 DE 60020220 T DE60020220 T DE 60020220T DE 60020220 T DE60020220 T DE 60020220T DE 60020220 D1 DE60020220 D1 DE 60020220D1
Authority
DE
Germany
Prior art keywords
blocking protein
plate adhesion
adhesion blocking
protein
plate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60020220T
Other languages
English (en)
Other versions
DE60020220T2 (de
Inventor
Wolfgang Strittmatter
Detlef Guessow
Uwe Hofmann
Juergen Hemberger
Zisi Fotev
Bernhard Scheuble
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE60020220D1 publication Critical patent/DE60020220D1/de
Publication of DE60020220T2 publication Critical patent/DE60020220T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE60020220T 1999-03-18 2000-03-10 Plättchenadhäsion blockierendes protein Expired - Lifetime DE60020220T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP99105530 1999-03-18
EP99105530 1999-03-18
EP99109503 1999-05-12
EP99109503 1999-05-12
PCT/EP2000/002117 WO2000056885A1 (de) 1999-03-18 2000-03-10 Protein for blocking platelet adhesion

Publications (2)

Publication Number Publication Date
DE60020220D1 true DE60020220D1 (de) 2005-06-23
DE60020220T2 DE60020220T2 (de) 2006-05-24

Family

ID=26152935

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60020220T Expired - Lifetime DE60020220T2 (de) 1999-03-18 2000-03-10 Plättchenadhäsion blockierendes protein

Country Status (27)

Country Link
US (3) US6774107B1 (de)
EP (1) EP1161530B1 (de)
JP (1) JP4805461B2 (de)
KR (1) KR100788219B1 (de)
CN (1) CN1185344C (de)
AR (1) AR023099A1 (de)
AT (1) ATE295883T1 (de)
AU (1) AU767172B2 (de)
BR (1) BR0009074A (de)
CA (1) CA2367457C (de)
CO (1) CO5241328A1 (de)
CZ (1) CZ301524B6 (de)
DE (1) DE60020220T2 (de)
DK (1) DK1161530T3 (de)
ES (1) ES2240067T3 (de)
HK (1) HK1045330B (de)
HU (1) HU228068B1 (de)
MX (1) MXPA01009363A (de)
MY (1) MY123371A (de)
NO (1) NO330769B1 (de)
PL (1) PL200384B1 (de)
PT (1) PT1161530E (de)
RU (1) RU2292351C2 (de)
SI (1) SI1161530T1 (de)
SK (1) SK287496B6 (de)
TR (1) TR200102729T2 (de)
WO (1) WO2000056885A1 (de)

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AU767172B2 (en) * 1999-03-18 2003-11-06 Merck Patent Gmbh Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
CA2453986A1 (en) * 2001-07-18 2003-01-30 Merck Patent Gesellschaft Mit Beschraenkter Haftung Glycoprotein vi fusion proteins
DE602004021022D1 (de) 2003-10-28 2009-06-18 Medtronic Inc Verfahren zur herstellung von vernetzten materialien und bioprothetischen vorrichtungen
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
EP1799828B1 (de) * 2004-10-12 2013-05-01 Board of Trustees of Michigan State University Biosynthese von Phloroglucinol und Herstellung von 1,3-Dihydroxybenzen daraus
CA2611102A1 (en) * 2005-05-26 2006-11-30 Thomas Jefferson University Method to treat and prevent posterior capsule opacification
WO2007038749A2 (en) * 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
US20080015145A1 (en) 2006-07-11 2008-01-17 Maria Gyongyossy-Issa Mimotope receptors and inhibitors for platelet-platelet and platelet-endothelium interactions
GB2462022B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
US8334372B2 (en) 2008-10-15 2012-12-18 Isis Pharmaceuticals, Inc. Modulation of factor 11 expression
WO2012003461A2 (en) 2010-07-02 2012-01-05 Draths Corporation Phloroglucinol synthases and methods of making and using the same
WO2012006244A1 (en) 2010-07-06 2012-01-12 Draths Corporation Method for producing phloroglucinol and dihydrophloroglucinol
WO2012006245A1 (en) 2010-07-06 2012-01-12 Draths Corporation Phloroglucinol reductase and methods of making and using the same
EP2606067B1 (de) 2010-08-19 2018-02-21 Zoetis Belgium S.A. Anti-ngf-antikörper und ihre verwendung
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
WO2013184871A1 (en) 2012-06-06 2013-12-12 Zoetis Llc Caninized anti-ngf antibodies and methods thereof
MX2015000789A (es) 2012-07-19 2015-05-07 Zoetis Llc Composiciones de virus de la gripe bovina.
AU2013295770A1 (en) 2012-07-27 2015-01-29 Zoetis Services Llc Tick toxin compositions
CA3153265A1 (en) 2016-08-17 2018-02-22 Pharmaq As Sea lice vaccine
BR102017005783A2 (pt) * 2017-03-21 2018-10-02 Fund Butantan processo de obtenção de esculptina e seus fragmentos, esculptina recombinante e seus usos
EP3765499A1 (de) 2018-03-12 2021-01-20 Zoetis Services LLC Anti-ngf-antikörper und verfahren dafür
KR20200142010A (ko) 2018-03-16 2020-12-21 조에티스 서비시즈 엘엘씨 인터루킨-31에 대한 펩티드 백신
KR20230145511A (ko) 2018-03-16 2023-10-17 조에티스 서비시즈 엘엘씨 수의학적 용도를 위한 인터류킨-31 단클론성 항체
BR112020020957B1 (pt) 2018-05-09 2022-05-10 Ionis Pharmaceuticals, Inc Compostos oligoméricos, população e composição farmacêutica dos mesmos e seus usos
BR112022004488A2 (pt) 2019-09-11 2022-05-31 Zoetis Services Llc Herpesvírus recombinante de vetores de peru que expressam antígenos de patógenos aviários e seus usos
US20220119513A1 (en) 2020-06-08 2022-04-21 Zoetis Services Llc Anti-tgfb antibodies and therapeutic uses thereof
US20210386854A1 (en) 2020-06-15 2021-12-16 Zoetis Services Llc Cell Line for Production of Marek's Disease Virus Vaccine and Methods of Making and Using the Same
WO2022076712A2 (en) 2020-10-07 2022-04-14 Zoetis Services Llc Anti-ngf antibodies and methods of use thereof
TW202221039A (zh) 2020-10-19 2022-06-01 美商碩騰服務公司 犬及貓抑瘤素Ｍ受體β之抗體及其用途
CA3232382A1 (en) 2021-09-27 2023-03-30 Zoetis Services Llc Anti- tgf.beta.1,2,3 antibodies and therapeutic uses thereof

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Publication number Priority date Publication date Assignee Title
US5705355A (en) * 1984-03-27 1998-01-06 Transgene, S.A. Hirudin, pharmaceutical compositions comprising it and their use
US4898734A (en) * 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
IL86857A (en) * 1988-06-24 1994-04-12 Yissum Res Dev Co Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
GB9022040D0 (en) * 1990-10-10 1990-11-21 Biopharm Ltd Platelet adhesion inhibitor
DE4136513A1 (de) * 1991-11-06 1993-05-13 Basf Ag Neues thrombininhibitorisches protein aus raubwanzen
EP0662088B1 (de) * 1993-07-01 2001-12-12 MERCK PATENT GmbH Ein inhibitor der collagenstimulierten plättchenaggregation
EP1118325B2 (de) * 1993-07-29 2010-01-06 The United States of America, represented by the Secretary, Department of Health and Human Services Verwendung von Paclitaxel und seinen Derivaten zur Herstellung eines Medikaments für die Behandlung von Restenose
CN1075836C (zh) * 1994-09-12 2001-12-05 舍林股份公司 修饰的胶原诱导血小板凝集抑制剂Pallidipin的制备方法
WO1996013585A1 (en) * 1994-10-28 1996-05-09 Clodica S.A. A novel family of protease inhibitors, and other biologic active substances
AU767172B2 (en) 1999-03-18 2003-11-06 Merck Patent Gmbh Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen

Also Published As

Publication number Publication date
NO20014506D0 (no) 2001-09-17
US6774107B1 (en) 2004-08-10
CA2367457C (en) 2010-09-21
CZ20013341A3 (cs) 2002-01-16
CN1344318A (zh) 2002-04-10
CZ301524B6 (cs) 2010-03-31
EP1161530A1 (de) 2001-12-12
US7090986B2 (en) 2006-08-15
PL200384B1 (pl) 2008-12-31
DE60020220T2 (de) 2006-05-24
AU3166200A (en) 2000-10-09
BR0009074A (pt) 2002-01-02
ATE295883T1 (de) 2005-06-15
KR100788219B1 (ko) 2007-12-26
CN1185344C (zh) 2005-01-19
CA2367457A1 (en) 2000-09-28
DK1161530T3 (da) 2005-08-08
US20050065084A1 (en) 2005-03-24
PT1161530E (pt) 2005-09-30
WO2000056885A1 (de) 2000-09-28
CO5241328A1 (es) 2003-01-31
HUP0200353A2 (hu) 2002-05-29
HUP0200353A3 (en) 2003-12-29
SI1161530T1 (en) 2005-10-31
JP4805461B2 (ja) 2011-11-02
NO330769B1 (no) 2011-07-11
EP1161530B1 (de) 2005-05-18
RU2292351C2 (ru) 2007-01-27
TR200102729T2 (tr) 2002-04-22
MY123371A (en) 2006-05-31
MXPA01009363A (es) 2002-06-04
US20060094079A1 (en) 2006-05-04
NO20014506L (no) 2001-11-16
KR20020008131A (ko) 2002-01-29
ES2240067T3 (es) 2005-10-16
SK12902001A3 (sk) 2002-03-05
SK287496B6 (sk) 2010-12-07
HU228068B1 (en) 2012-09-28
HK1045330B (zh) 2005-09-09
AU767172B2 (en) 2003-11-06
AR023099A1 (es) 2002-09-04
US6962801B2 (en) 2005-11-08
JP2002539788A (ja) 2002-11-26
PL350147A1 (en) 2002-11-04
HK1045330A1 (en) 2002-11-22

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