DE60021715D1 - Phospahatasen mit verbesserter phytase-aktivität - Google Patents

Phospahatasen mit verbesserter phytase-aktivität

Info

Publication number
DE60021715D1
DE60021715D1 DE60021715T DE60021715T DE60021715D1 DE 60021715 D1 DE60021715 D1 DE 60021715D1 DE 60021715 T DE60021715 T DE 60021715T DE 60021715 T DE60021715 T DE 60021715T DE 60021715 D1 DE60021715 D1 DE 60021715D1
Authority
DE
Germany
Prior art keywords
phytase activity
phosphatase
improved
phospahatases
improved phytase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60021715T
Other languages
English (en)
Other versions
DE60021715T2 (de
Inventor
Xingen Lei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell Research Foundation Inc
Original Assignee
Cornell Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Research Foundation Inc filed Critical Cornell Research Foundation Inc
Application granted granted Critical
Publication of DE60021715D1 publication Critical patent/DE60021715D1/de
Publication of DE60021715T2 publication Critical patent/DE60021715T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
DE60021715T 1999-03-31 2000-03-31 Phospahatasen mit verbesserter phytase-aktivität Expired - Lifetime DE60021715T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12703299P 1999-03-31 1999-03-31
US127032P 1999-03-31
PCT/US2000/008590 WO2000058481A2 (en) 1999-03-31 2000-03-31 Phosphatases with improved phytase activity

Publications (2)

Publication Number Publication Date
DE60021715D1 true DE60021715D1 (de) 2005-09-08
DE60021715T2 DE60021715T2 (de) 2006-06-01

Family

ID=22427982

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60021715T Expired - Lifetime DE60021715T2 (de) 1999-03-31 2000-03-31 Phospahatasen mit verbesserter phytase-aktivität

Country Status (12)

Country Link
US (2) US6511699B1 (de)
EP (1) EP1165806B1 (de)
CN (1) CN100347303C (de)
AT (1) ATE301198T1 (de)
AU (1) AU4056700A (de)
BR (1) BR0009516B1 (de)
CA (1) CA2365418C (de)
DE (1) DE60021715T2 (de)
DK (1) DK1165806T3 (de)
ES (1) ES2248067T3 (de)
MX (1) MXPA01009809A (de)
WO (1) WO2000058481A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7432097B2 (en) 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US6183740B1 (en) 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US7078035B2 (en) 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US6451572B1 (en) * 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
RS18304A (en) 2001-08-27 2006-10-27 Syngenta Participations Ag. Self processing plants and plant parts
WO2003037102A2 (en) * 2001-10-31 2003-05-08 Phytex, Llc Phytase-containing animal food and method
TW200305430A (en) 2001-12-28 2003-11-01 Syngenta Participations Ag Thermotolerant phytase for animal feed
TWI262083B (en) * 2001-12-28 2006-09-21 Syngenta Participations Ag Microbially-expressed thermotolerant phytase for animal feed
CA2498017C (en) 2002-09-13 2016-06-14 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
WO2004085638A1 (en) * 2003-03-25 2004-10-07 Republic Of National Fisheries Research And Development Institute Phytase produced from citrobacter braakii
EP2143338A1 (de) * 2004-09-27 2010-01-13 Novozymes A/S Enzymgranulat
US7658922B2 (en) 2005-06-24 2010-02-09 Ab Enzymes Gmbh Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
EP2069486A2 (de) * 2006-08-03 2009-06-17 Cornell Research Foundation, Inc. Phytasen mit erhöhter wärmestabilität
EP2617728B1 (de) * 2006-09-21 2016-03-09 BASF Enzymes LLC Phytasen, dafür kodierende Nukleinsäuren sowie Verfahren zu deren Herstellung und Verwendung
CA2681392C (en) * 2007-03-26 2017-08-01 Novozymes A/S Hafnia phytase
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
DK2933329T3 (en) * 2008-09-26 2017-07-24 Novozymes As Hafniaphytase variants
ES2608690T3 (es) 2009-05-21 2017-04-12 Basf Enzymes Llc Fitasas, ácidos nucleicos que las codifican y métodos para su producción y uso
CA2904333A1 (en) 2013-03-08 2014-09-12 Biogrammatics, Inc. Yeast promoters for protein expression
PT2964765T (pt) 2013-03-08 2019-08-02 Keck Graduate Inst Of Applied Life Sciences Promotores de levedura de pichia pastoris
CN104703170B (zh) 2013-12-05 2017-04-12 华为终端有限公司 下载运营商的文件的方法及设备
KR102126010B1 (ko) 2014-05-23 2020-06-23 후아웨이 테크놀러지 컴퍼니 리미티드 Euicc 관리 방법, euicc, sm 플랫폼 및 시스템
US10351832B2 (en) 2016-06-30 2019-07-16 Fornia Biosolutions, Inc. Phytases and uses thereof
US9528096B1 (en) * 2016-06-30 2016-12-27 Fornia Biosolutions, Inc. Phytases and uses thereof
US9605245B1 (en) 2016-06-30 2017-03-28 Fornia BioSoultions, Inc. Phytases and uses thereof

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US554399A (en) * 1896-02-11 Charles e
US3431195A (en) * 1967-04-17 1969-03-04 Universal Oil Prod Co Purifying make hydrogen in a catalytic reforming process
US3430418A (en) * 1967-08-09 1969-03-04 Union Carbide Corp Selective adsorption process
CA940070A (en) 1968-12-23 1974-01-15 Jim S. Berry Stabilized aqueous enzyme composition
US3564816A (en) * 1968-12-30 1971-02-23 Union Carbide Corp Selective adsorption process
US3860484A (en) 1972-09-28 1975-01-14 Xerox Corp Enzyme stabilization
DE2426988C2 (de) 1974-06-04 1985-02-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Trägerbindung biologisch aktiver Proteine
US3966971A (en) 1975-01-02 1976-06-29 Grain Processing Corporation Separation of protein from vegetable sources
US3986849A (en) * 1975-11-07 1976-10-19 Union Carbide Corporation Selective adsorption process
DE2931999A1 (de) 1979-08-03 1981-02-26 Schering Ag Herstellung und anwendung von neukombinierten plasmiden mit genen fuer alkalische phosphatasen
DE3126759A1 (de) 1981-07-07 1983-01-27 Boehringer Mannheim Gmbh, 6800 Mannheim Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung
JPS5931799A (ja) 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
US4470968A (en) 1983-01-13 1984-09-11 Miles Laboratories, Inc. Pasteurized therapeutically active blood coagulation factor concentrates
SE450325B (sv) 1983-02-23 1987-06-22 Tricum Ab Kostfiberprodukt baserad pa skaldelar fran froet hos ceralier
US4547205A (en) * 1984-10-11 1985-10-15 Uop Inc. Dehydrocyclodimerization process
SE465951B (sv) 1984-10-23 1991-11-25 Perstorp Ab Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
DE3515586A1 (de) 1985-04-30 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes sarcosinoxidase-praeparat
US5024941A (en) 1985-12-18 1991-06-18 Biotechnica International, Inc. Expression and secretion vector for yeast containing a glucoamylase signal sequence
JPH0655146B2 (ja) 1985-12-27 1994-07-27 財団法人化学及血清療法研究所 シヤトルベクタ−
US5780292A (en) 1987-04-29 1998-07-14 Alko Group Ltd. Production of phytate degrading enzymes in trichoderma
US4915029A (en) * 1987-03-05 1990-04-10 Halliburton Company Shaped charge carrier assembly method
NL8702735A (nl) 1987-11-17 1989-06-16 Dorr Oliver Inc Werkwijze voor het weken van granen met een nieuw enzympreparaat.
GB8826429D0 (en) 1988-11-11 1988-12-14 Univ Leeds Ind Service Ltd Enzyme stabilisation systems
US5316770A (en) 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5366736A (en) 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
UA27702C2 (uk) 1989-09-27 2000-10-16 Гіст-Брокейдс Н.В. Фрагмент геномної днк, що кодує фітазу aspergillus niger,фрагмент кднк, що кодує фітазу aspergillus niger, рекомбінантна плазмідна днк для експресії фітази в aspergillus (варіанти), штам aspergillus-продуцент фітази aspergillus (варіанти), спосіб одержання фітази, рекомбінанта фітаза aspergillus niger
SK466390A3 (en) 1989-09-27 2000-05-16 Gist Brocades Nv Purified and isolated dna sequence, construct, vector, transformed cell, peptide or protein having phytase activity, process for its preparation, and its use
US5012037A (en) * 1990-01-10 1991-04-30 Uop Integrated thermal swing-pressure swing adsorption process for hydrogen and hydrocarbon recovery
KR100225087B1 (ko) 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
IL97645A (en) 1990-03-23 1997-03-18 Gist Brocades Nv Production of enzymes in seeds and their use
GB9006642D0 (en) 1990-03-24 1990-05-23 Gibson Timothy D Enzyme stabilisation
DE4011084A1 (de) 1990-04-05 1991-10-10 Boehringer Mannheim Gmbh Saccharid-modifizierte, wasserloesliche proteine
US5200399A (en) 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
CA2073511A1 (en) 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5268273A (en) 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
JP2981302B2 (ja) * 1991-05-13 1999-11-22 東洋エンジニアリング株式会社 ガスの分離方法
DE4119281A1 (de) 1991-06-12 1992-12-17 Basf Ag Verfahren zur herstellung von enzymzubereitungen
US5178751A (en) * 1991-11-27 1993-01-12 Uop Two-stage process for purifying a hydrogen gas and recovering liquifiable hydrocarbons from hydrocarbonaceous effluent streams
JPH06505881A (ja) 1992-01-24 1994-07-07 ギスト　ブロカデス　ナムローゼ　フェンノートシャップ 飼料ペレットの製造方法
IL104704A0 (en) 1992-02-13 1993-06-10 Gist Brocades Nv Stabilized aqueous liquid formulation of phytase
US5834286A (en) 1992-07-31 1998-11-10 Rohm Enzyme Finland Oy Recombinant cells that express phytate degrading enzymes in desired ratios
EP0619369B2 (de) 1993-04-05 2009-09-30 Aveve N.V. Phytate-Hydrolyse und enzymatische Zusammensetzung für die Hydrolyse von Phytat
JP2696057B2 (ja) 1993-05-11 1998-01-14 ニチモウ株式会社 穀類を原料とした生成物の製造方法
FR2715802B1 (fr) 1994-02-04 1996-03-15 Rhone Poulenc Nutrition Animal Utilisation d'enzymes dans l'alimentation des animaux pour réduire les rejets azotés.
US5955448A (en) 1994-08-19 1999-09-21 Quadrant Holdings Cambridge Limited Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
JP3678310B2 (ja) * 1994-04-22 2005-08-03 ノボザイムス アクティーゼルスカブ 植物性タンパク質の溶解度を改善する方法
ATE332378T1 (de) 1994-04-25 2006-07-15 Dsm Ip Assets Bv Polypeptide mit phytase wirkung
US5830732A (en) 1994-07-05 1998-11-03 Mitsui Toatsu Chemicals, Inc. Phytase
GB9416841D0 (en) 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
FR2729971B1 (fr) 1995-01-31 1997-06-06 Roquette Freres Composition nutritive resultant de la trempe du mais et son procede d'obtention
US5935624A (en) 1995-02-06 1999-08-10 Wisconsin Alumni Research Foundation Low phosphorus animal feed containing 1α-hydroxylated vitamin D compounds and method of preparing
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
CZ87497A3 (cs) 1995-07-28 1998-03-18 Gist-Brocades B. V. Enzymové přípravky stabilizované pomocí solí
EP0858266A1 (de) 1995-11-02 1998-08-19 Novo Nordisk A/S Futterzusammensetzung aus enzymen
DK172530B1 (da) 1995-11-10 1998-11-23 Leo Pharm Prod Ltd Tilsætningsprodukt til drikkevand og foder til dyr samt fremgangsmåde for tilsætning
US5830696A (en) 1996-12-05 1998-11-03 Diversa Corporation Directed evolution of thermophilic enzymes
WO1997035016A1 (en) 1996-03-18 1997-09-25 Novo Nordisk Biotech Inc Polypeptides having phytase activity and nucleic acids encoding same
PL329160A1 (en) 1996-04-05 1999-03-15 Kyowa Hakko Kogyo Kk Novel phytase and phytase encoding gene
WO1997039638A1 (en) 1996-04-23 1997-10-30 Novo Nordisk A/S Animal feed additives
AU3214597A (en) 1996-05-29 1998-01-05 Universal Preservation Technologies, Inc. Long-term shelf preservation by vitrification
US5985605A (en) 1996-06-14 1999-11-16 Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada DNA sequences encoding phytases of ruminal microorganisms
FR2751333B1 (fr) 1996-07-18 1998-09-25 Roquette Freres Composition nutritive amelioree resultant de la trempe du mais et son procede d'obtention
FR2751987B1 (fr) 1996-08-01 1998-12-31 Biocem Phytases de plantes et applications biotechnologiques
GB2316082A (en) 1996-08-13 1998-02-18 Finnfeeds Int Ltd Phytase
SE507355C2 (sv) 1996-09-18 1998-05-18 Semper Ab Förfarande för reducering av halten fytat i korn av spannmål
KR20000036143A (ko) 1996-09-25 2000-06-26 히라다 다다시 신규피틴산 분해효소 및 그의 제조방법
GB2319030A (en) 1996-11-05 1998-05-13 Finnfeeds Int Ltd Phytase extracted from soybean
US6039942A (en) 1996-12-20 2000-03-21 Novo Nordick A/S Phytase polypeptides
AU5477898A (en) 1997-01-09 1998-08-03 Novo Nordisk A/S Phytase combinations
KR100222638B1 (ko) 1997-01-20 1999-10-01 배희동 종자를 이용한 효소산물 및 사료원료의 생산
CA2231948C (en) 1997-03-25 2010-05-18 F. Hoffmann-La Roche Ag Modified phytases
KR100206453B1 (ko) 1997-03-27 1999-07-01 박원훈 신규한플라즈미드를이용하여형질전환시킨균주 이.채씨오엘아이.피와이로부터생산된피타제
WO1998054305A1 (en) 1997-05-28 1998-12-03 Primary Applications Pty. Limited Enhancement of industrial enzymes
NZ330940A (en) 1997-07-24 2000-02-28 F Production of consensus phytases from fungal origin using computer programmes
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US6183740B1 (en) 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US5876997A (en) 1997-08-13 1999-03-02 Diversa Corporation Phytase
US6022555A (en) 1997-09-05 2000-02-08 Wisconsin Alumni Research Foundation Animal feed containing carboxylic acids
EP1659173A1 (de) 1997-10-01 2006-05-24 DSMIP Assets B.V. Verfahren zur Protein-Herstellung
DE19743683A1 (de) 1997-10-02 1999-04-08 Basf Ag Verfahren zur Änderung der Substratspezifität von Enzymen
US20010018197A1 (en) 1997-12-23 2001-08-30 Protein Technologies International, Inc. Method for producing ultrapure vegetable protein materials
EP0925723B1 (de) 1997-12-23 2003-04-02 Cargill BV Proteine enthaltendes Futtermittel und Verfahren zur Herstellung
CN1192103C (zh) 1998-01-27 2005-03-09 三井化学株式会社 生产植酸酶的方法
US6284502B1 (en) 1998-08-21 2001-09-04 University Of Saskatchewan Process for converting phytate into inorganic phosphate
FR2804691B1 (fr) 2000-02-04 2003-11-07 Roquette Freres Composition azotee resultant de l'hydrolyse du gluten de mais et son procede de fabrication

Also Published As

Publication number Publication date
WO2000058481A9 (en) 2002-08-29
ATE301198T1 (de) 2005-08-15
US20030072844A1 (en) 2003-04-17
CN100347303C (zh) 2007-11-07
DE60021715T2 (de) 2006-06-01
MXPA01009809A (es) 2002-07-30
WO2000058481A3 (en) 2001-01-04
US6511699B1 (en) 2003-01-28
US6974690B2 (en) 2005-12-13
BR0009516B1 (pt) 2013-09-10
DK1165806T3 (da) 2005-12-05
ES2248067T3 (es) 2006-03-16
EP1165806A2 (de) 2002-01-02
AU4056700A (en) 2000-10-16
WO2000058481A2 (en) 2000-10-05
CA2365418C (en) 2009-05-26
CA2365418A1 (en) 2000-10-05
CN1413253A (zh) 2003-04-23
EP1165806B1 (de) 2005-08-03
BR0009516A (pt) 2001-12-26

Similar Documents

Publication Publication Date Title
ATE301198T1 (de) Phospahatasen mit verbesserter phytase-aktivität
PL319782A1 (en) Inhibitors of serinic proteases and anticoagulative protecins extracted from nematodes
ATE548451T1 (de) Hybridproteine von aktives-zentrum-serin-beta- lactamase
MXPA03000786A (es) Peptidos de promiostatina y metodos de usar los mismos.
CY1111771T1 (el) Ενζυμα τα οποια εχουν δραστικοτητα αλφα αμυλασης και μεθοδοι χρησεις τους
IL150168A0 (en) Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods bsed thereon
NZ596269A (en) Protease screening methods and proteases identified thereby
ATE290086T1 (de) Herstellung von phytat-degradierenden enzymen in trichoderma
WO2002000860A3 (en) Novel proteases
ATE317441T1 (de) Cathepsin-02-protease
WO2000022110A3 (en) Targeted proteolysis by recruitment to ubiquitin protein ligases
ATE414775T1 (de) Polypeptide mit prolyldipeptidylaminopeptidase- aktivität und dafür kodierende nukleinsäuren
ATE343369T1 (de) Neue verwendung von proteinhydrolysaten
AU3175197A (en) Recombinant blood-coagulation proteases
ATE452184T1 (de) Mikrobielle trypsinvarianten mit chymotrypsinaktivität und diese codierende nukleinsäuren
FI946076A (fi) Modifioituja Kluyveromyces-hiivoja, valmistus ja käyttö
DK0942992T3 (da) O-fucosyltransferase
EA200200319A1 (ru) Белок iren, его получение и использование
ATE323505T1 (de) Verwendung von rekombinantem lungensurfactant zur frühbehandlung von akuten lungenerkrankungen
ATE345383T1 (de) Säugeradhäsionprotease
ATE328082T1 (de) Verkürztes bard1 protein und dessen diagnostische und therapeutische anwendungen
DK1141337T3 (da) Gram-positive bakterier, som mangler HtrA-proteaseaktivitet, samt deres anvendelser
EA200100440A1 (ru) Ген prv-1 и его применение
ATE308339T1 (de) Kombination der proteolytischen enzyme trypsin, bromelain und papain zur behandlung von glomerulonephritis
WO2001074998A3 (fr) Nouveau polypeptide, proteine humaine de regulation 10 de la serine proteinase, et polynucleotide codant pour ce polypeptide

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC