DE60028370D1 - Verfahren zur herstellung einer selektiv vernetzten medizinischen prothese aus polyethylen, sowie eine dergestalt hergestellte prothese - Google Patents

Verfahren zur herstellung einer selektiv vernetzten medizinischen prothese aus polyethylen, sowie eine dergestalt hergestellte prothese

Info

Publication number
DE60028370D1
DE60028370D1 DE60028370T DE60028370T DE60028370D1 DE 60028370 D1 DE60028370 D1 DE 60028370D1 DE 60028370 T DE60028370 T DE 60028370T DE 60028370 T DE60028370 T DE 60028370T DE 60028370 D1 DE60028370 D1 DE 60028370D1
Authority
DE
Germany
Prior art keywords
prosthetic
polyethylene
manufactured
production
medical prosthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60028370T
Other languages
English (en)
Other versions
DE60028370T2 (de
Inventor
Aiguo Wang
Paul Essner
J Zarnowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Howmedica Osteonics Corp
Original Assignee
Howmedica Osteonics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howmedica Osteonics Corp filed Critical Howmedica Osteonics Corp
Publication of DE60028370D1 publication Critical patent/DE60028370D1/de
Application granted granted Critical
Publication of DE60028370T2 publication Critical patent/DE60028370T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/0266—Local curing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/0844—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using X-ray
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/085—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using gamma-ray
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0866—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation
    • B29C2035/0877—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation using electron radiation, e.g. beta-rays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0608—PE, i.e. polyethylene characterised by its density
    • B29K2023/065—HDPE, i.e. high density polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0675—HMWPE, i.e. high molecular weight polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0683—UHMWPE, i.e. ultra high molecular weight polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0088—Blends of polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037—Other properties
    • B29K2995/0087—Wear resistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
DE60028370T 1999-04-21 2000-04-20 Verfahren zur herstellung einer selektiv vernetzten medizinischen prothese aus polyethylen, sowie eine dergestalt hergestellte prothese Expired - Lifetime DE60028370T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13032299P 1999-04-21 1999-04-21
US130322P 1999-04-21
PCT/US2000/010673 WO2000062717A1 (en) 1999-04-21 2000-04-20 Selectively cross-linked polyethylene orthopedic devices

Publications (2)

Publication Number Publication Date
DE60028370D1 true DE60028370D1 (de) 2006-07-06
DE60028370T2 DE60028370T2 (de) 2007-05-03

Family

ID=22444146

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60028370T Expired - Lifetime DE60028370T2 (de) 1999-04-21 2000-04-20 Verfahren zur herstellung einer selektiv vernetzten medizinischen prothese aus polyethylen, sowie eine dergestalt hergestellte prothese

Country Status (7)

Country Link
US (3) US6849224B2 (de)
EP (1) EP1178764B1 (de)
JP (1) JP2002541916A (de)
AU (1) AU760210C (de)
CA (1) CA2370208C (de)
DE (1) DE60028370T2 (de)
WO (1) WO2000062717A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US8563623B2 (en) * 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
US6414086B1 (en) 2000-02-29 2002-07-02 Howmedica Osteonics Corp. Compositions, processes and methods of improving the wear resistance of prosthetic medical devices
US7205339B2 (en) * 2000-12-12 2007-04-17 Massachusetts General Hospital Selective controlled manipulation of polymers
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
US7186364B2 (en) * 2002-01-28 2007-03-06 Depuy Products, Inc. Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same
CA2429930C (en) 2002-06-06 2008-10-14 Howmedica Osteonics Corp. Sequentially cross-linked polyethylene
JP2006511255A (ja) * 2002-10-11 2006-04-06 カーティフィシャル・アクティーゼルスカブ 層状構造を持つ生体適合性ポリマー製品を含む医療機器
US20050054952A1 (en) * 2003-09-05 2005-03-10 Scimed Life Systems, Inc. Elongated medical device for intracorporal use
US7540845B2 (en) * 2003-09-05 2009-06-02 Boston Scientific Scimed, Inc Medical device coil
US7833175B2 (en) * 2003-09-05 2010-11-16 Boston Scientific Scimed, Inc. Medical device coil
FR2885294B1 (fr) * 2005-05-03 2008-04-04 Jerome Levieux Prothese de disque intervertebral
AU2006259555B2 (en) * 2005-06-14 2011-03-03 Omni Life Science, Inc. Crosslinked polyethylene article
US8343230B2 (en) * 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
US20070203564A1 (en) * 2006-02-28 2007-08-30 Boston Scientific Scimed, Inc. Biodegradable implants having accelerated biodegradation properties in vivo
DE102006011159A1 (de) * 2006-03-10 2007-09-13 Benecke-Kaliko Ag Verfahren zur Herstellung einer thermoplastischen Folie
WO2008101116A1 (en) * 2007-02-14 2008-08-21 Brigham And Women's Hospital, Inc. Crosslinked polymers and methods of making the same
US20100042225A1 (en) * 2007-08-27 2010-02-18 Vladimir Shur Knee prosthesis
DE102008029056A1 (de) * 2008-06-18 2009-12-31 GKN Aerospace Services Limited, East Cowes Herstellungsverfahren für Bauteile aus faserverstärktem Verbundwerkstoff mit Mikrowellen
GB0922339D0 (en) 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
US8865051B1 (en) 2012-01-24 2014-10-21 Mercury Plastics, Inc. Method of making a crosslinked overmolded assembly
DE102012103079A1 (de) * 2012-04-10 2013-10-10 Krones Ag Rollenförderer für Kunststoffvorformlinge
CA2913845A1 (en) * 2013-05-23 2014-11-27 Ceramtec Gmbh Component consisting of ceramics comprising pore channels
CN103751849A (zh) * 2013-12-24 2014-04-30 四川大学 一种人工关节用可熔体加工的超高分子量聚乙烯复合材料
US20150230926A1 (en) * 2014-02-18 2015-08-20 Biomet Manufacturing, Llc Method and device for reducing implant contamination from handling

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544324A (de) 1955-01-11
US2904480A (en) 1955-06-06 1959-09-15 Grace W R & Co Polyethylene
US3563869A (en) 1957-11-05 1971-02-16 Grace W R & Co Irradiated polyethylene
US3022543A (en) 1958-02-07 1962-02-27 Grace W R & Co Method of producing film having improved shrink energy
US3057791A (en) 1959-07-06 1962-10-09 Phillips Petroleum Co Radiation curing of polymers
US3090770A (en) 1960-04-26 1963-05-21 Grace W R & Co Blended polyethylene compositions of improved clarity and method of making same
US3162623A (en) 1961-12-26 1964-12-22 Du Pont Crosslinking of polymers with nitrogen fluorides
US3297641A (en) 1964-01-17 1967-01-10 Grace W R & Co Process for cross-linking polyethylene
DE1241994B (de) 1964-01-31 1967-06-08 Glanzstoff Ag Verfahren zur Absaettigung von Doppelbindungen in Polyolefinen
DE1669649B2 (de) 1966-05-27 1971-05-19 Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen Verfahren zum herstellen feinteiliger schaumfoermiger olefin polymerisate mit hoher waermestandfestigkeit
US3832827A (en) * 1967-12-18 1974-09-03 J Lemelson Container forming and filling apparatus
US3758273A (en) 1970-04-03 1973-09-11 Gillette Co Processes for sterilizing polypropylene objects
JPS526314B2 (de) 1971-11-01 1977-02-21
AU523866B2 (en) 1978-04-18 1982-08-19 Du Pont Canada Inc. Manufacture of film
GB2060469B (en) 1979-06-06 1983-09-28 Nat Res Dev Drawing thermoplastics material
JPS5971830A (ja) * 1982-10-18 1984-04-23 Nippon Sheet Glass Co Ltd 屈折率分布型レンズ体の製造方法
GB8332952D0 (en) 1983-12-09 1984-01-18 Ward I M Polymer irradiation
US4587163A (en) 1984-03-06 1986-05-06 Zachariades Anagnostis E Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance
CA1252265A (en) 1984-03-30 1989-04-11 Ian M. Ward Tubular materials
EP0161802B1 (de) 1984-04-13 1990-06-27 National Research Development Corporation Verfahren zum Verformen im festen Zustand
US4655769A (en) 1984-10-24 1987-04-07 Zachariades Anagnostis E Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states
US4820466A (en) 1985-01-31 1989-04-11 Zachariades Anagnostis E Process for obtaining ultra-high modulus products
US4950151A (en) 1985-01-31 1990-08-21 Zachariades Anagnostic E Rolling die for producing high modulus products
DE3545116A1 (de) 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
US4701288A (en) * 1985-06-05 1987-10-20 Bausch & Lomb Incorporated Method of making articles of dissimilar polymer compositions
JPS6274364A (ja) 1985-09-27 1987-04-06 株式会社　ニツシヨ− 医療用具
GB2207436B (en) 1987-07-24 1991-07-24 Nat Research And Dev Corp The Solid phase deformation process
GB8827967D0 (en) 1988-11-30 1989-01-05 Ward I M Die-free drawing
WO1990006140A1 (en) 1988-12-02 1990-06-14 E.I. Du Pont De Nemours And Company Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
US5030402A (en) 1989-03-17 1991-07-09 Zachariades Anagnostis E Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties
US5037928A (en) 1989-10-24 1991-08-06 E. I. Du Pont De Nemours And Company Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
US5160677A (en) * 1989-12-15 1992-11-03 United States Surgical Corporation Pressurized powder support for treating processes
US5153039A (en) 1990-03-20 1992-10-06 Paxon Polymer Company, L.P. High density polyethylene article with oxygen barrier properties
US5348788A (en) 1991-01-30 1994-09-20 Interpore Orthopaedics, Inc. Mesh sheet with microscopic projections and holes
US5508319A (en) 1991-06-21 1996-04-16 Montell North America Inc. High melt strength, ethylene polymer, process for making it, and use thereof
US5222949A (en) * 1991-07-23 1993-06-29 Intermed, Inc. Flexible, noncollapsible catheter tube with hard and soft regions
US5414049A (en) 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
US5849437A (en) * 1994-03-25 1998-12-15 Fujitsu Limited Electron beam exposure mask and method of manufacturing the same and electron beam exposure method
EP0729981B1 (de) * 1994-09-21 2002-03-20 Bmg Incorporated Polyethylenguss mit ultrahohem molekulargewicht für künstliche verbindungen und verfahren zu dessen herstellung
US5962023A (en) * 1995-03-06 1999-10-05 Ethicon, Inc. Hydrogels containing absorbable polyoxaamides
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
JP3565652B2 (ja) * 1996-04-25 2004-09-15 富士通株式会社 荷電粒子ビーム露光装置用透過マスク及びそれを利用した露光装置
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
WO1998016258A1 (en) * 1996-10-15 1998-04-23 The Orthopaedic Hospital Wear resistant surface-gradient cross-linked polyethylene
US6432349B1 (en) * 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
US6365089B1 (en) * 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant

Also Published As

Publication number Publication date
JP2002541916A (ja) 2002-12-10
AU760210B2 (en) 2003-05-08
AU4650600A (en) 2000-11-02
CA2370208A1 (en) 2000-10-26
DE60028370T2 (de) 2007-05-03
US6818171B2 (en) 2004-11-16
WO2000062717A1 (en) 2000-10-26
EP1178764B1 (de) 2006-05-31
EP1178764A4 (de) 2003-04-02
US20020093124A1 (en) 2002-07-18
US20020100879A1 (en) 2002-08-01
AU760210C (en) 2004-10-07
US6849224B2 (en) 2005-02-01
EP1178764A1 (de) 2002-02-13
CA2370208C (en) 2008-09-09
US20050113935A1 (en) 2005-05-26

Similar Documents

Publication Publication Date Title
DE60028370D1 (de) Verfahren zur herstellung einer selektiv vernetzten medizinischen prothese aus polyethylen, sowie eine dergestalt hergestellte prothese
DE50002122D1 (de) Resorbierbares knochen-implantatmaterial sowie verfahren zur herstellung desselben
DE60210480D1 (de) Wasser absorbierendes harzpulver sowie verfahren zur herstellung und verwendung desselben
DE60007339D1 (de) Flexibler endoluminarer stent und verfahren zur herstellung
DE60110067D1 (de) Poröser polypropylenfilm, verfahren zu dessen herstellung sowie den film verwendender absorbierender gegenstand
DE69921506D1 (de) Mehrschichtige struktur zur verpackung und daraus hergestellte verpackungsbehälter, sowie verfahren zur herstellung dieser struktur
DE69940075D1 (de) Organisch-inorganisch gradiertes mehrschichtmaterial sowie verfahren zu dessen herstellung und benutzung
DE69431730T2 (de) Gebogenes, prothetisches netz, sowie verfahren zur herstellung
DE60129244D1 (de) Dreidimensionales tissuepapier und verfahren zu dessen herstellung
DE59911122D1 (de) Antifoulingmittel, ein Verfahren zur Herstellung und deren Verwendung sowie daraus hergestellte Antifoulingbeschichtungen
DE50207943D1 (de) Kristallines anticholinergikum, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels
ATE218863T1 (de) Pharmazeutische formulierungen enthaltend ein 2(((2-pyridinyl)methyl)sulfinyl)benzimidazol mit antiulcus wirkung und verfahren zur herstellung solcher formulierungen
DE60141806D1 (de) Silikongummi in form eines feinverteilten puders sowie verfahren zur herstellung und verwendung desselben
DE60032943D1 (de) Imid-benzoxazolpolykondensat sowie verfahren zur herstellung
ATE266985T1 (de) Verfahren zur herstellung einer prothese
DE50010576D1 (de) Verfahren zur herstellung eines knochenimplantats
DE69924242D1 (de) Verbesserte vaskuläre ptfe-prothese und verfahren zu ihrer herstellung
DE60126943D1 (de) Kaelteresistente fettzusammensetzung sowie verfahren zur herstellung derselben
DE602004027730D1 (de) Medizinisches knochenprothesematerial und verfahren zu seiner herstellung
DE60103024D1 (de) Verfahren zur herstellung, beladung und abdichtung einer zellen -oder medikamenteneinkapselungsvorrichtung sowie eine entsprechende vorrichtung
ATA6302000A (de) Haftmittel für zahnprothesen und verfahren zu seiner herstellung
DE69933139D1 (de) Verfahren zur herstellung von polyethylen
DE60028757D1 (de) Polyolefinzusammensetzung, verfahren zur herstellung und die verwendung davon
DE60116275D1 (de) Verfahren zur herstellung eines titansilicalitformkörpers
DE59601823D1 (de) Zahnrestaurations- oder prothesenteil aus keramikmaterial sowie verfahren zu seiner herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition