DE60036053D1 - Erythropoietin Derivate - Google Patents

Erythropoietin Derivate

Info

Publication number
DE60036053D1
DE60036053D1 DE60036053T DE60036053T DE60036053D1 DE 60036053 D1 DE60036053 D1 DE 60036053D1 DE 60036053 T DE60036053 T DE 60036053T DE 60036053 T DE60036053 T DE 60036053T DE 60036053 D1 DE60036053 D1 DE 60036053D1
Authority
DE
Germany
Prior art keywords
erythropoietin derivatives
erythropoietin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60036053T
Other languages
English (en)
Other versions
DE60036053T2 (de
Inventor
Pascal Sebastian Bailon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27495518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60036053(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60036053D1 publication Critical patent/DE60036053D1/de
Publication of DE60036053T2 publication Critical patent/DE60036053T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
DE60036053T 1999-07-02 2000-06-28 Erythropoietinkonjugate Expired - Lifetime DE60036053T2 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US14225499P 1999-07-02 1999-07-02
US142254 1999-07-02
US15022599P 1999-08-23 1999-08-23
US150225 1999-08-23
US15154899P 1999-08-31 1999-08-31
US151548 1999-08-31
US16615199P 1999-11-17 1999-11-17
US166151 1999-11-17

Publications (2)

Publication Number Publication Date
DE60036053D1 true DE60036053D1 (de) 2007-10-04
DE60036053T2 DE60036053T2 (de) 2008-01-03

Family

ID=27495518

Family Applications (3)

Application Number Title Priority Date Filing Date
DE60036053T Expired - Lifetime DE60036053T2 (de) 1999-07-02 2000-06-28 Erythropoietinkonjugate
DE122007000064C Active DE122007000064I2 (de) 1999-07-02 2000-06-28 Erythropoietinkonjugate
DE10031839A Ceased DE10031839A1 (de) 1999-07-02 2000-06-30 Erythropoietinkonjugate

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE122007000064C Active DE122007000064I2 (de) 1999-07-02 2000-06-28 Erythropoietinkonjugate
DE10031839A Ceased DE10031839A1 (de) 1999-07-02 2000-06-30 Erythropoietinkonjugate

Country Status (52)

Country Link
US (2) US6583272B1 (de)
EP (2) EP1064951B1 (de)
JP (2) JP3727009B2 (de)
KR (1) KR100593143B1 (de)
CN (2) CN1184233C (de)
AR (2) AR024625A1 (de)
AT (1) ATE370748T1 (de)
AU (1) AU736067B2 (de)
BG (1) BG65449B1 (de)
BR (2) BRPI0002276B8 (de)
CA (1) CA2310536C (de)
CO (1) CO5190661A1 (de)
CY (2) CY1107719T1 (de)
CZ (1) CZ299516B6 (de)
DE (3) DE60036053T2 (de)
DK (1) DK1064951T3 (de)
DO (1) DOP2000000030A (de)
EA (1) EA003777B1 (de)
ES (2) ES2289985T3 (de)
FR (2) FR2795734B1 (de)
GB (2) GB2393960C (de)
GC (1) GC0000197A (de)
GE (1) GEP20022804B (de)
GT (1) GT200000109A (de)
HK (2) HK1033328A1 (de)
HR (1) HRP20000436B1 (de)
HU (1) HU226233B1 (de)
ID (1) ID26447A (de)
IL (1) IL137056A0 (de)
IS (1) IS2492B (de)
IT (1) IT1318606B1 (de)
LU (1) LU91363I2 (de)
MA (1) MA26746A1 (de)
MX (1) MXPA00006547A (de)
MY (1) MY128500A (de)
NL (1) NL300289I9 (de)
NO (2) NO327043B1 (de)
NZ (1) NZ505454A (de)
OA (1) OA11442A (de)
PA (1) PA8497801A1 (de)
PE (1) PE20010297A1 (de)
PL (1) PL202758B1 (de)
PT (1) PT1064951E (de)
RS (1) RS49928B (de)
SG (1) SG92717A1 (de)
SI (1) SI1064951T1 (de)
SK (1) SK286301B6 (de)
SV (1) SV2002000120A (de)
TN (1) TNSN00147A1 (de)
TR (1) TR200001956A2 (de)
TW (1) TWI235667B (de)
UY (1) UY26228A1 (de)

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