DE60036382D1 - Verfahren zur verabreichung von arzneimitteln mit bindungsaffinität zum plasmaprotein und verwendung der zusammensetzung in dem verfahren - Google Patents
Verfahren zur verabreichung von arzneimitteln mit bindungsaffinität zum plasmaprotein und verwendung der zusammensetzung in dem verfahrenInfo
- Publication number
- DE60036382D1 DE60036382D1 DE60036382A DE60036382A DE60036382D1 DE 60036382 D1 DE60036382 D1 DE 60036382D1 DE 60036382 A DE60036382 A DE 60036382A DE 60036382 A DE60036382 A DE 60036382A DE 60036382 D1 DE60036382 D1 DE 60036382D1
- Authority
- DE
- Germany
- Prior art keywords
- plasma protein
- administration
- binding
- drug
- saffinity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17351499 | 1999-06-21 | ||
PCT/JP2000/004039 WO2000078352A1 (fr) | 1999-06-21 | 2000-06-21 | Procede d'administration de medicaments possedant une affinite de liaison aux proteines plasmatiques et preparation utilisee pour la mise en oeuvre dudit procede |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60036382D1 true DE60036382D1 (de) | 2007-10-25 |
Family
ID=15961945
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60036382A Expired - Lifetime DE60036382D1 (de) | 1999-06-21 | 2000-06-21 | Verfahren zur verabreichung von arzneimitteln mit bindungsaffinität zum plasmaprotein und verwendung der zusammensetzung in dem verfahren |
DE60036382T Expired - Lifetime DE60036382T4 (de) | 1999-06-21 | 2000-06-21 | Verfahren zur Verabreichung von Arzneimitteln mit Bindungsaffinität zu Plasmaprotein und Präparat zur Verwendung in dem Verfahren |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60036382T Expired - Lifetime DE60036382T4 (de) | 1999-06-21 | 2000-06-21 | Verfahren zur Verabreichung von Arzneimitteln mit Bindungsaffinität zu Plasmaprotein und Präparat zur Verwendung in dem Verfahren |
Country Status (8)
Country | Link |
---|---|
US (2) | US7029653B1 (de) |
EP (1) | EP1197227B9 (de) |
JP (1) | JP4343473B2 (de) |
AT (1) | ATE372785T1 (de) |
CA (1) | CA2376159C (de) |
DE (2) | DE60036382D1 (de) |
ES (1) | ES2290042T3 (de) |
WO (1) | WO2000078352A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4343473B2 (ja) * | 1999-06-21 | 2009-10-14 | 日本メジフィジックス株式会社 | 血漿蛋白質に結合親和性を有する薬剤の投与方法並びに当該投与方法に用いられる製剤 |
JPWO2004024188A1 (ja) * | 2002-09-12 | 2006-01-05 | 日本メジフィジックス株式会社 | 薬物の血漿蛋白質結合を制御するための製剤 |
CA2500866C (en) | 2002-10-31 | 2013-06-25 | Nihon Medi-Physics Co., Ltd. | Method of measuring binding site on plasma protein of plasma protein-binding drug and method of measuring plasma protein mutation |
GB0427392D0 (en) * | 2004-12-15 | 2005-01-19 | Amersham Plc | Stabilised 99mTc compositions |
US9321095B2 (en) | 2010-06-30 | 2016-04-26 | General Electric Company | Apparatuses and methods for cutting porous substrates |
CN105745030B (zh) * | 2014-03-13 | 2022-04-15 | 斯泰瓦纳托集团国际 A.S. | 处理液体药物制剂的方法 |
CN117030905B (zh) * | 2023-10-09 | 2024-01-05 | 成都华西海圻医药科技有限公司 | 一种快速定量血浆中丁二酮浓度的lc-ms/ms分析方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4520112A (en) * | 1983-03-09 | 1985-05-28 | The Johns Hopkins University | Assay method for organic calcium antagonist drugs and a kit for such an assay |
US4642284A (en) * | 1983-06-13 | 1987-02-10 | Scripps Clinic And Research Foundation | Method and system for detection of complement pathway activation |
US4976950A (en) | 1988-12-19 | 1990-12-11 | The Dow Chemical Company | Bone marrow suppressing agents |
US5792444A (en) * | 1989-05-09 | 1998-08-11 | The General Hospital Corporation | Labeled chemotactic peptides to image focal sites of infection or inflammation |
US6022541A (en) | 1991-10-18 | 2000-02-08 | Beth Israel Deaconess Medical Center | Immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor bound in-vivo to a tumor associated blood vessel |
EP0932399B1 (de) * | 1996-03-12 | 2006-01-04 | PG-TXL Company, L.P. | Wasserlösliche paclitaxel-prodrogen |
DE19648629A1 (de) | 1996-11-12 | 1998-05-14 | Meisegeier Bernhard Dr | Verfahren zur immunologischen Erfassung und Produktion von Antikörpern |
JP4343473B2 (ja) * | 1999-06-21 | 2009-10-14 | 日本メジフィジックス株式会社 | 血漿蛋白質に結合親和性を有する薬剤の投与方法並びに当該投与方法に用いられる製剤 |
-
2000
- 2000-06-21 JP JP2001504414A patent/JP4343473B2/ja not_active Expired - Fee Related
- 2000-06-21 ES ES00940773T patent/ES2290042T3/es not_active Expired - Lifetime
- 2000-06-21 US US10/018,745 patent/US7029653B1/en not_active Expired - Fee Related
- 2000-06-21 WO PCT/JP2000/004039 patent/WO2000078352A1/ja active IP Right Grant
- 2000-06-21 CA CA2376159A patent/CA2376159C/en not_active Expired - Fee Related
- 2000-06-21 DE DE60036382A patent/DE60036382D1/de not_active Expired - Lifetime
- 2000-06-21 DE DE60036382T patent/DE60036382T4/de not_active Expired - Lifetime
- 2000-06-21 EP EP00940773A patent/EP1197227B9/de not_active Expired - Lifetime
- 2000-06-21 AT AT00940773T patent/ATE372785T1/de not_active IP Right Cessation
-
2006
- 2006-02-14 US US11/353,152 patent/US20060140857A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2290042T3 (es) | 2008-02-16 |
EP1197227B1 (de) | 2007-09-12 |
ATE372785T1 (de) | 2007-09-15 |
DE60036382T4 (de) | 2008-09-25 |
CA2376159C (en) | 2010-09-14 |
WO2000078352A1 (fr) | 2000-12-28 |
DE60036382T2 (de) | 2008-06-12 |
JP4343473B2 (ja) | 2009-10-14 |
US20060140857A1 (en) | 2006-06-29 |
US7029653B1 (en) | 2006-04-18 |
CA2376159A1 (en) | 2000-12-28 |
EP1197227A1 (de) | 2002-04-17 |
EP1197227A4 (de) | 2002-12-04 |
EP1197227B9 (de) | 2008-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: NIHON MEDI-PHYSICS CO., LTD., TOKYO, JP |
|
8364 | No opposition during term of opposition |