DE60044623D1 - Vorrichtung zur zentrifugalen Trennung und Verfahren zur Trennung von Flüssigkeitsbestandteilen - Google Patents

Vorrichtung zur zentrifugalen Trennung und Verfahren zur Trennung von Flüssigkeitsbestandteilen

Info

Publication number
DE60044623D1
DE60044623D1 DE60044623T DE60044623T DE60044623D1 DE 60044623 D1 DE60044623 D1 DE 60044623D1 DE 60044623 T DE60044623 T DE 60044623T DE 60044623 T DE60044623 T DE 60044623T DE 60044623 D1 DE60044623 D1 DE 60044623D1
Authority
DE
Germany
Prior art keywords
separation vessel
platelets
separation
fluid
fluid chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044623T
Other languages
English (en)
Inventor
Dennis Hlavinka
Thomas J Felt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Terumo BCT Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo BCT Inc filed Critical Terumo BCT Inc
Application granted granted Critical
Publication of DE60044623D1 publication Critical patent/DE60044623D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles
DE60044623T 1999-03-16 2000-03-07 Vorrichtung zur zentrifugalen Trennung und Verfahren zur Trennung von Flüssigkeitsbestandteilen Expired - Lifetime DE60044623D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/270,105 US6334842B1 (en) 1999-03-16 1999-03-16 Centrifugal separation apparatus and method for separating fluid components

Publications (1)

Publication Number Publication Date
DE60044623D1 true DE60044623D1 (de) 2010-08-12

Family

ID=23029929

Family Applications (4)

Application Number Title Priority Date Filing Date
DE60044624T Expired - Lifetime DE60044624D1 (de) 1999-03-16 2000-03-07 Vorrichtung zur zentrifugalen Trennung von Flüssigkeitsbestandteilen
DE60044623T Expired - Lifetime DE60044623D1 (de) 1999-03-16 2000-03-07 Vorrichtung zur zentrifugalen Trennung und Verfahren zur Trennung von Flüssigkeitsbestandteilen
DE60041426T Expired - Lifetime DE60041426D1 (de) 1999-03-16 2000-03-07 Zentrifugale Trennvorrichtung und Verfahren zur Trennung von Flüssigkeitsbestandteilen
DE60036906T Expired - Lifetime DE60036906T2 (de) 1999-03-16 2000-03-07 Zentrifugale trennvorrichtung und verfahren zur trennung von flüssigkeitsbestandteilen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60044624T Expired - Lifetime DE60044624D1 (de) 1999-03-16 2000-03-07 Vorrichtung zur zentrifugalen Trennung von Flüssigkeitsbestandteilen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE60041426T Expired - Lifetime DE60041426D1 (de) 1999-03-16 2000-03-07 Zentrifugale Trennvorrichtung und Verfahren zur Trennung von Flüssigkeitsbestandteilen
DE60036906T Expired - Lifetime DE60036906T2 (de) 1999-03-16 2000-03-07 Zentrifugale trennvorrichtung und verfahren zur trennung von flüssigkeitsbestandteilen

Country Status (7)

Country Link
US (4) US6334842B1 (de)
EP (4) EP1847323B1 (de)
JP (3) JP4771595B2 (de)
AT (4) ATE376886T1 (de)
DE (4) DE60044624D1 (de)
ES (4) ES2292438T3 (de)
WO (1) WO2000054886A1 (de)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334842B1 (en) 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
JP3817091B2 (ja) * 1999-07-02 2006-08-30 テルモ株式会社 細胞数測定装置
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US7651474B2 (en) 1999-10-01 2010-01-26 Caridianbct, Inc. Method and apparatus for leukoreduction of red blood cells
EP1363739B1 (de) * 2000-11-02 2011-12-21 CaridianBCT, Inc. Vorrichtungen, systeme und verfahren zur fluidtrennung
JP4299452B2 (ja) * 2000-11-28 2009-07-22 テルモ株式会社 血小板採取装置
US6835316B2 (en) 2001-04-09 2004-12-28 Medtronic, Inc. Clam shell blood reservoir holder with index line
US6610002B2 (en) * 2001-04-09 2003-08-26 Medtronic, Inc. Method for handling blood sample to ensure blood components are isolated
DE60237091D1 (de) * 2001-04-09 2010-09-02 Arteriocyte Medical Systems In Mikrozentrifuge und antrieb dafür
US6579219B2 (en) * 2001-04-09 2003-06-17 Medtronic, Inc. Centrifuge bag and methods of use
US6582350B2 (en) * 2001-04-09 2003-06-24 Medtronic, Inc. Centrifuge container having curved linear shape
US6890291B2 (en) * 2001-06-25 2005-05-10 Mission Medical, Inc. Integrated automatic blood collection and processing unit
DE60230997D1 (de) * 2001-12-05 2009-03-12 Caridianbct Inc Verfahren und vorrichtung zur trennung von blutbestandteilen
US7052606B2 (en) * 2001-12-10 2006-05-30 Gambro, Inc. Methods and apparatus for leukoreduction of red blood cells
US20030173274A1 (en) * 2002-02-01 2003-09-18 Frank Corbin Blood component separation device, system, and method including filtration
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
US7211037B2 (en) * 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
ATE382382T1 (de) * 2002-04-16 2008-01-15 Gambro Bct Inc System und verfahren zur aufarbeitung von blutbestandteilen
WO2003089926A2 (en) * 2002-04-19 2003-10-30 Mission Medical, Inc. Integrated automatic blood processing unit
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7118676B2 (en) * 2003-09-04 2006-10-10 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US7699767B2 (en) 2002-07-31 2010-04-20 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US7297272B2 (en) * 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
US7327443B2 (en) * 2004-07-01 2008-02-05 Gambro Bct, Inc Stroboscopic LED light source for blood processing apparatus
CN103454191B (zh) 2003-07-02 2016-01-06 泰尔茂比司特公司 用于利用预测数据分析算法控制血液处理离心机的方法
US20050049539A1 (en) * 2003-09-03 2005-03-03 O'hara Gerald P. Control system for driving fluids through an extracorporeal blood circuit
US7671975B2 (en) * 2004-07-01 2010-03-02 Caridianbct, Inc. Blood processing apparatus with dedicated stroboscopic controller for LED source
US20060147895A1 (en) * 2004-10-22 2006-07-06 Cryofacets, Inc. System, chamber, and method for fractionation, elutriation, and decontamination of fluids containing cellular components
WO2006047296A1 (en) * 2004-10-22 2006-05-04 Cryofacets, Inc. System, chamber, and method for fractionation and elutriation of fluids containing particulate components
US7476209B2 (en) * 2004-12-21 2009-01-13 Therakos, Inc. Method and apparatus for collecting a blood component and performing a photopheresis treatment
WO2006086199A1 (en) * 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
EP1848474B1 (de) 2005-02-07 2013-06-12 Hanuman LLC Vorrichtung und verfahren mit blutplättchenreichem plasmakonzentrat
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
EP1933899A1 (de) * 2005-10-05 2008-06-25 Gambro BCT, Inc. Verfahren und gerät für die leukoreduktion von roten blutkörperchen
US7386815B2 (en) * 2005-10-27 2008-06-10 International Business Machines Corporation Test yield estimate for semiconductor products created from a library
WO2007070301A2 (en) * 2005-12-05 2007-06-21 Regeneration Technologies, Inc. Vascular graft sterilization and decellularization
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20080035585A1 (en) * 2006-08-10 2008-02-14 Gambro Bct, Inc. Method and Apparatus for Recirculating Elutriation Fluids
US20080041772A1 (en) * 2006-08-17 2008-02-21 Gambro Bct, Inc. Blood Processing Apparatus with Robust Outflow Process Control
EP2092293B1 (de) 2006-08-17 2015-08-19 Terumo BCT, Inc. Blutaufarbeitungsvorrichtung mit robuster auslaufprozesskontrolle
US8337379B2 (en) * 2006-08-17 2012-12-25 Terumo Bct, Inc. Blood processing apparatus with robust automated process control
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
JP5479319B2 (ja) 2007-04-12 2014-04-23 バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー ブイ式懸濁液分画システム
US7857744B2 (en) * 2007-06-19 2010-12-28 Caridianbct, Inc. Blood processing apparatus with flared cell capture chamber and method
US8057376B2 (en) * 2007-12-18 2011-11-15 Caridianbct, Inc. Blood processing apparatus with sealed diffuser in optical control apparatus
EP2234659B1 (de) * 2007-12-27 2019-07-24 Terumo BCT, Inc. Blutbehandlungsgerät mit kontrolliertem zellenspeicherkammer-auslöser
US8685258B2 (en) * 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
EP2567692B1 (de) 2008-02-27 2016-04-06 Biomet Biologics, LLC Verwendung einer Vorrichtung zur Erzeugung Interleukin-1-rezeptorantagonistreicher Lösungen
US8337711B2 (en) * 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US8012077B2 (en) * 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
US20100015690A1 (en) * 2008-07-16 2010-01-21 Ortho-Clinical Diagnostics, Inc. Use of fluid aspiration/dispensing tip as a microcentrifuge tube
US7963901B2 (en) * 2008-09-12 2011-06-21 Caridianbct, Inc. Blood processing apparatus with cell capture chamber with protruding inlet
US7951059B2 (en) * 2008-09-18 2011-05-31 Caridianbct, Inc. Blood processing apparatus with optical reference control
US7828709B2 (en) * 2008-09-30 2010-11-09 Caridianbct, Inc. Blood processing apparatus with incipient spill-over detection
WO2010074929A2 (en) * 2008-12-22 2010-07-01 Caridianbct, Inc. Blood processing apparatus with digitally controlled linear voltage regulator for optical pulses
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) * 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
KR101940440B1 (ko) 2009-10-06 2019-01-18 사토리우스 스테딤 노쓰 아메리카 인크. 입자를 조작하는 방법, 시스템 및 장치
WO2011071773A1 (en) 2009-12-11 2011-06-16 Caridianbct, Inc. System for blood separation with shielded extraction port and optical control
MY160835A (en) 2010-03-18 2017-03-31 Syngen Inc System for purifying certain cell populations in blood or bone marrow by depleting others
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
EP2590697B1 (de) 2011-06-13 2015-03-04 Terumo BCT, Inc. System zur bluttrennung mit trennkammern mit seitengewindebohrung
EP2717942B1 (de) 2011-06-13 2016-05-18 Terumo BCT, Inc. System zur bluttrennung mit einem schwerkraftventil zur steuerung einer trennkammer mit seitengewindebohrung
WO2013096778A1 (en) 2011-12-21 2013-06-27 Lonza Walkersville Inc. Scalable process for therapeutic cell concentration and residual clearance
US9327296B2 (en) 2012-01-27 2016-05-03 Fenwal, Inc. Fluid separation chambers for fluid processing systems
US9033858B2 (en) 2012-02-02 2015-05-19 Fenwal, Inc. Method and apparatus for concentrating platelets from platelet-rich plasma
WO2013152253A1 (en) 2012-04-05 2013-10-10 Terumo Bct, Inc. Syestem and method for collecting and treating plasma protein fractions
US9421317B2 (en) * 2012-06-08 2016-08-23 Pall Corporation Cell harvesting device and system
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
CN104349805B (zh) 2012-09-25 2017-06-23 干细胞合伙有限责任公司 制备单供体凝血酶血清的方法和装置
WO2014127122A1 (en) 2013-02-18 2014-08-21 Terumo Bct, Inc. System for blood separation with a separation chamber having an internal gravity valve
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
US10618060B2 (en) 2013-12-20 2020-04-14 Terumo Bct, Inc. Centrifuge safety mechanism
WO2015117007A1 (en) 2014-01-31 2015-08-06 Dsm Ip Assets B.V. Adipose tissue centrifuge and method of use
US10166322B2 (en) 2014-03-28 2019-01-01 Terumo Bct, Inc. Gain in separation processes with control loop
RU2708206C2 (ru) 2014-08-14 2019-12-04 ТЕРУМО БиСиТи, ИНК. Обработка частиц
SG11201706777QA (en) 2015-02-19 2017-09-28 Premium Genetics (Uk) Ltd Scanning infrared measurement system
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
EP3124063B1 (de) 2015-07-29 2019-04-10 Fenwal, Inc. Bluttrennkammer mit fünf anschlüssen und verfahren zur verwendung davon
CN109982731B (zh) 2016-10-03 2022-08-19 泰尔茂比司特公司 离心流体分离设备
JP6934938B2 (ja) 2016-10-13 2021-09-15 テルモ ビーシーティー、インコーポレーテッド 流体の成分の収集
CN106823475B (zh) * 2017-02-07 2023-01-24 重庆科技学院 一种血液分流器
WO2019010186A1 (en) * 2017-07-03 2019-01-10 Trustees Of Tufts College TWO-PHASE AQUEOUS SYSTEM FOR THE SEPARATION AND RECOVERY OF MAMMALIAN CELLS FROM CONTAMINATED CROPS
EP3796998A1 (de) 2018-05-23 2021-03-31 ABS Global, Inc. Systeme und verfahren zur teilchenfokussierung in mikrokanälen
KR102063865B1 (ko) * 2018-06-20 2020-01-08 울산과학기술원 원심력 기반 혈소판 분리 및 검진 장치
CN111686326A (zh) 2019-03-12 2020-09-22 泰尔茂株式会社 治疗方法、分离方法及过滤器组装体
JP2020151465A (ja) 2019-03-12 2020-09-24 テルモ株式会社 治療方法、分離方法およびフィルター組立体
BR112021020390A2 (pt) 2019-04-18 2022-01-18 Abs Global Inc Sistema de distribuição de crioprotetor, sistema de criopreservação para distribuir um crioprotetor a um espécime biológico, método para distribuir um crioprotetor a um espécime biológico, sistema de distribuição e método para preparar um espécime biológico para criopreservação
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
WO2023009539A1 (en) * 2021-07-26 2023-02-02 Georgia Tech Research Corporation Rapid, label-free antibiotic susceptibility of bacteria directly from positive blood or bodily fluid/culture
US11912974B2 (en) * 2021-12-06 2024-02-27 Hossein HEIDARI Assembly and method for spatiotemporal control of chemical, biological, and biochemical reactions

Family Cites Families (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1684870A (en) 1927-10-17 1928-09-18 Frank D Lewis Centrifugal concentrating and amalgamating apparatus of the vertical type
US2616619A (en) 1948-08-30 1952-11-04 Norman A Macleod Method and apparatus for centrifugal elutriation
US2878995A (en) 1953-08-24 1959-03-24 Gen Motors Corp Centrifuge for liquids
DE2157900C3 (de) 1970-11-24 1980-01-03 Escher Wyss Ag, Zuerich (Schweiz) Selbstreinigende Vollmantelzentrifuge
US3957931A (en) * 1970-12-18 1976-05-18 Mass Transfer Limited Fluid-fluid contact method and apparatus
FR2180589B1 (de) 1972-04-21 1975-03-21 Loison Robert
US4934995A (en) 1977-08-12 1990-06-19 Baxter International Inc. Blood component centrifuge having collapsible inner liner
US3825175A (en) 1973-06-06 1974-07-23 Atomic Energy Commission Centrifugal particle elutriator and method of use
ZA762830B (en) * 1975-05-21 1977-04-27 Norton Co Trickling filters media for biological filters
US4010894A (en) 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
US4007871A (en) 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container
US4059967A (en) * 1976-02-19 1977-11-29 The Community Blood Council Of Greater New York, Inc. Process for freezing blood platelets
US4425112A (en) 1976-02-25 1984-01-10 The United States Of America As Represented By The Department Of Health And Human Services Flow-through centrifuge
DE2658926A1 (de) 1976-12-24 1978-06-29 Heraeus Christ Gmbh Zentrifuge zum waschen von blut
US4091989A (en) 1977-01-04 1978-05-30 Schlutz Charles A Continuous flow fractionation and separation device and method
US4430072A (en) 1977-06-03 1984-02-07 International Business Machines Corporation Centrifuge assembly
US4094461A (en) 1977-06-27 1978-06-13 International Business Machines Corporation Centrifuge collecting chamber
US4356958A (en) 1977-07-19 1982-11-02 The United States Of America As Represented By The Secretary Of Health And Human Services Blood cell separator
US4419089A (en) 1977-07-19 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Blood cell separator
US5217427A (en) 1977-08-12 1993-06-08 Baxter International Inc. Centrifuge assembly
US5571068A (en) 1977-08-12 1996-11-05 Baxter International Inc. Centrifuge assembly
US5006103A (en) 1977-08-12 1991-04-09 Baxter International Inc. Disposable container for a centrifuge
US4198972A (en) * 1978-04-17 1980-04-22 Pharmachem Corporation Blood and blood component storage bags
US4387848A (en) 1977-10-03 1983-06-14 International Business Machines Corporation Centrifuge assembly
US4146172A (en) 1977-10-18 1979-03-27 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing system
US4386730A (en) 1978-07-21 1983-06-07 International Business Machines Corporation Centrifuge assembly
US4187979A (en) 1978-09-21 1980-02-12 Baxter Travenol Laboratories, Inc. Method and system for fractionating a quantity of blood into the components thereof
US4413772A (en) 1979-09-10 1983-11-08 E. I. Du Pont De Nemours And Company Apparatus for centrifugal separation
US4413771A (en) 1979-09-10 1983-11-08 E. I. Du Pont De Nemours And Company Method and apparatus for centrifugal separation
US4268393A (en) 1980-05-05 1981-05-19 The Institutes Of Medical Sciences Apparatus for centrifugal separation of platelet-rich plasma
US4269718A (en) 1980-05-05 1981-05-26 The Institutes Of Medical Sciences Process and device for centrifugal separation of platelets
US4350283A (en) 1980-07-01 1982-09-21 Beckman Instruments, Inc. Centrifugal elutriator rotor
US4316576A (en) 1980-11-06 1982-02-23 Baxter Travenol Laboratories, Inc. Method and chamber for separating granulocytes from whole blood
DE3274800D1 (en) 1981-02-05 1987-02-05 Asahi Chemical Ind Apparatus for separating blood components
US4322298A (en) 1981-06-01 1982-03-30 Advanced Blood Component Technology, Inc. Centrifugal cell separator, and method of use thereof
US4421503A (en) 1981-07-09 1983-12-20 Haemonetics Corporation Fluid processing centrifuge and apparatus thereof
US4464167A (en) 1981-09-03 1984-08-07 Haemonetics Corporation Pheresis apparatus
US4416654A (en) 1981-09-03 1983-11-22 Haemonetics Corporation Pheresis apparatus
US4447221A (en) * 1982-06-15 1984-05-08 International Business Machines Corporation Continuous flow centrifuge assembly
US4680025A (en) 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods
US4610846A (en) 1983-08-18 1986-09-09 Hans Martin Compartmentalized centrifugation chamber
DE3578502D1 (de) 1984-03-15 1990-08-09 Asahi Medical Co Filtereinheit zum abtrennen von leukozyten.
DE3410286C2 (de) 1984-03-21 1986-01-23 Fresenius AG, 6380 Bad Homburg Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens
US4776964A (en) 1984-08-24 1988-10-11 William F. McLaughlin Closed hemapheresis system and method
US4647279A (en) 1985-10-18 1987-03-03 Cobe Laboratories, Inc. Centrifugal separator
US4846974A (en) 1985-11-14 1989-07-11 Norfolk Scientific, Inc. Centrifuge system and fluid container therefor
US4708710A (en) 1986-03-27 1987-11-24 E. I. Du Pont De Nemours And Company Particle separation process
JPH0651060B1 (de) 1986-03-28 1994-07-06 Asahi Medical Co
US4708712A (en) * 1986-03-28 1987-11-24 Cobe Laboratories, Inc. Continuous-loop centrifugal separator
US4915847A (en) 1987-08-04 1990-04-10 Baxter International Inc. Cryoglobulin separation
US4933291A (en) 1986-12-22 1990-06-12 Eastman Kodak Company Centrifugable pipette tip and pipette therefor
DE3700122A1 (de) 1987-01-03 1988-07-14 Manfred Lutz Kammer zur trennung eines teilchengemisches nach dem gegenstromzentrifugationsverfahren
US5213970A (en) 1987-01-23 1993-05-25 Board Of Regents, The University Of Texas System Method for obtaining soluble antitumor factor
US4834890A (en) 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
US5076911A (en) 1987-01-30 1991-12-31 Baxter International Inc. Centrifugation chamber having an interface detection surface
US5641414A (en) * 1987-01-30 1997-06-24 Baxter International Inc. Blood processing systems and methods which restrict in flow of whole blood to increase platelet yields
US5792372A (en) * 1987-01-30 1998-08-11 Baxter International, Inc. Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma
US5628915A (en) 1987-01-30 1997-05-13 Baxter International Inc. Enhanced yield blood processing systems and methods establishing controlled vortex flow conditions
US5656163A (en) 1987-01-30 1997-08-12 Baxter International Inc. Chamber for use in a rotating field to separate blood components
US5370802A (en) 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
DE3711177A1 (de) 1987-04-02 1988-10-13 Dornier System Gmbh Verfahren und vorrichtung zum betrieb von wirbelschicht-reaktoren
US4808151A (en) 1987-04-27 1989-02-28 E. I. Du Pont De Nemours And Company Simplified method for the preparation of human lymphokine activated killer cells
US4939087A (en) 1987-05-12 1990-07-03 Washington State University Research Foundation, Inc. Method for continuous centrifugal bioprocessing
US4939081A (en) 1987-05-27 1990-07-03 The Netherlands Cancer Institute Cell-separation
SE458342B (sv) 1987-07-06 1989-03-20 Alfa Laval Ab Centrifugalseparator innefattande en rotor med en separeringskammare bestaaende av tvaa avdelningar
US4798579A (en) 1987-10-30 1989-01-17 Beckman Instruments, Inc. Rotor for centrifuge
US4851126A (en) 1987-11-25 1989-07-25 Baxter International Inc. Apparatus and methods for generating platelet concentrate
US4936820A (en) 1988-10-07 1990-06-26 Baxter International Inc. High volume centrifugal fluid processing system and method for cultured cell suspensions and the like
US5078671A (en) 1988-10-07 1992-01-07 Baxter International Inc. Centrifugal fluid processing system and method
CA1334189C (en) 1988-10-07 1995-01-31 T. Michael Dennehey Centrifugal fluid processing system and method
US5344561A (en) 1989-05-09 1994-09-06 Pall Corporation Device for depletion of the leucocyte content of blood and blood components
US5229012A (en) 1989-05-09 1993-07-20 Pall Corporation Method for depletion of the leucocyte content of blood and blood components
US5316667A (en) 1989-05-26 1994-05-31 Baxter International Inc. Time based interface detection systems for blood processing apparatus
EP0406485A1 (de) 1989-07-03 1991-01-09 NPBI Nederlands Produktielaboratorium voor Bloedtransfusieapparatuur en Infusievloeistoffen B.V. Verfahren zur Abscheidung von Leukocyten aus einer Leukocyten enthaltenden Suspension und Filter zur Verwendung dazu
DE69020248T2 (de) 1989-07-14 1996-01-25 Terumo Corp Filtermaterial zum Abscheiden von Leukozyten und Verfahren zu seiner Herstellung.
US5100564A (en) 1990-11-06 1992-03-31 Pall Corporation Blood collection and processing system
US5152905A (en) 1989-09-12 1992-10-06 Pall Corporation Method for processing blood for human transfusion
JP2523938B2 (ja) 1989-09-18 1996-08-14 テルモ株式会社 血小板純化用フィルタ―
US5089146A (en) 1990-02-12 1992-02-18 Miles Inc. Pre-storage filtration of platelets
US5224921A (en) 1990-05-31 1993-07-06 Baxter International Inc. Small volume collection chamber
US5217627A (en) 1990-11-06 1993-06-08 Pall Corporation System and method for processing biological fluid
FR2671985B1 (fr) 1991-01-30 1993-04-09 Snecma Filtre a huile centrifuge avec collecte des particules.
US5282982A (en) 1991-07-12 1994-02-01 Wells John R Blood washing method
DE4126341C1 (de) 1991-08-09 1993-01-28 Fresenius Ag, 6380 Bad Homburg, De
DE4132965A1 (de) 1991-10-04 1993-04-08 Fresenius Ag Vorrichtung zur trennung von medien in deren bestandteile
AU652888B2 (en) 1991-12-23 1994-09-08 Baxter International Inc. Centrifugal processing system with direct access drawer
US5690835A (en) 1991-12-23 1997-11-25 Baxter International Inc. Systems and methods for on line collection of cellular blood components that assure donor comfort
CA2103911C (en) 1991-12-23 1999-08-24 Warren P. Williamson, Iv Centrifuge with separable bowl and spool elements providing access to the separation chamber
US5549834A (en) 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5437624A (en) 1993-08-23 1995-08-01 Cobe Laboratories, Inc. Single needle recirculation system for harvesting blood components
DE4226974C2 (de) 1992-08-14 1994-08-11 Fresenius Ag Verfahren und Vorrichtung zur kontinuierlichen Aufbereitung einer Zellsuspension
US5397479A (en) 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
DE69425966T2 (de) 1993-04-27 2001-03-29 Haemonetics Corp Apheresisgerät
US5547591A (en) 1993-06-01 1996-08-20 Asahi Medical Co., Ltd. Method for separating a blood material into blood components by centrifugation, and centrifugal apparatus
US5409813A (en) 1993-09-30 1995-04-25 Systemix, Inc. Method for mammalian cell separation from a mixture of cell populations
US5704888A (en) 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Intermittent collection of mononuclear cells in a centrifuge apparatus
US5704889A (en) 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
US5913768A (en) 1995-04-18 1999-06-22 Cobe Laboratories, Inc. Particle filter apparatus
US5674173A (en) 1995-04-18 1997-10-07 Cobe Laboratories, Inc. Apparatus for separating particles
US6053856A (en) * 1995-04-18 2000-04-25 Cobe Laboratories Tubing set apparatus and method for separation of fluid components
DE69638219D1 (de) 1995-04-18 2010-08-26 Caridianbct Inc Teilchentrennverfahren
US5720716A (en) 1995-06-07 1998-02-24 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5702357A (en) 1995-06-07 1997-12-30 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5958250A (en) * 1995-06-07 1999-09-28 Baxter International Inc. Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent
US5846439A (en) * 1996-02-28 1998-12-08 Marshfield Medical Research & Education Foundation, A Division Of Marshfield Clinic Method of concentrating waterborne protozoan parasites
US5792038A (en) 1996-05-15 1998-08-11 Cobe Laboratories, Inc. Centrifugal separation device for providing a substantially coriolis-free pathway
US5904645A (en) 1996-05-15 1999-05-18 Cobe Laboratories Apparatus for reducing turbulence in fluid flow
EP0907420B1 (de) 1996-05-15 2000-08-30 Gambro, Inc., Verfahren und vorrichtung zum reduzieren von turbulenzen in flüssigkeitsströmungen
US6334842B1 (en) 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
US6354986B1 (en) * 2000-02-16 2002-03-12 Gambro, Inc. Reverse-flow chamber purging during centrifugal separation
US7120254B2 (en) * 2000-10-30 2006-10-10 Geocodex Llc Cryptographic system and method for geolocking and securing digital information
USD445029S1 (en) * 2001-01-30 2001-07-17 Saint-Gobain Norpro Corporation Packing element
US6931429B2 (en) * 2001-04-27 2005-08-16 Left Gate Holdings, Inc. Adaptable wireless proximity networking

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ATE472374T1 (de) 2010-07-15
DE60036906T2 (de) 2008-08-21
EP1082176A1 (de) 2001-03-14
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JP4771595B2 (ja) 2011-09-14
EP1854545A3 (de) 2008-07-23
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US20060191857A1 (en) 2006-08-31
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US7029430B2 (en) 2006-04-18
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EP1847323B1 (de) 2010-06-30
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