DE60100389D1 - Fettlösliche Substanzen enthaltende Granulate und Verfahren zu ihrer Herstellung - Google Patents

Fettlösliche Substanzen enthaltende Granulate und Verfahren zu ihrer Herstellung

Info

Publication number
DE60100389D1
DE60100389D1 DE60100389T DE60100389T DE60100389D1 DE 60100389 D1 DE60100389 D1 DE 60100389D1 DE 60100389 T DE60100389 T DE 60100389T DE 60100389 T DE60100389 T DE 60100389T DE 60100389 D1 DE60100389 D1 DE 60100389D1
Authority
DE
Germany
Prior art keywords
water
production
soluble substances
granules containing
containing fat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60100389T
Other languages
English (en)
Other versions
DE60100389T2 (de
Inventor
Alberto Reiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
APR Applied Pharma Research SA
Fidia Farmaceutici SpA
Ipsen SpA
Original Assignee
APR Applied Pharma Research SA
Fidia Farmaceutici SpA
Ipsen SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by APR Applied Pharma Research SA, Fidia Farmaceutici SpA, Ipsen SpA filed Critical APR Applied Pharma Research SA
Publication of DE60100389D1 publication Critical patent/DE60100389D1/de
Application granted granted Critical
Publication of DE60100389T2 publication Critical patent/DE60100389T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE60100389T 2001-07-11 2001-07-11 Fettlösliche Substanzen enthaltende Granulate und Verfahren zu ihrer Herstellung Expired - Lifetime DE60100389T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202657A EP1275377B1 (de) 2001-07-11 2001-07-11 Fettlösliche Substanzen enthaltende Granulate und Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
DE60100389D1 true DE60100389D1 (de) 2003-07-24
DE60100389T2 DE60100389T2 (de) 2004-05-19

Family

ID=8180628

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60100389T Expired - Lifetime DE60100389T2 (de) 2001-07-11 2001-07-11 Fettlösliche Substanzen enthaltende Granulate und Verfahren zu ihrer Herstellung

Country Status (21)

Country Link
US (1) US7615547B2 (de)
EP (1) EP1275377B1 (de)
JP (1) JP2004536118A (de)
KR (1) KR100877628B1 (de)
AT (1) ATE243028T1 (de)
AU (1) AU2002328866B2 (de)
BR (1) BR0211081A (de)
CA (1) CA2452386C (de)
DE (1) DE60100389T2 (de)
DK (1) DK1275377T3 (de)
ES (1) ES2199202T3 (de)
HR (1) HRP20040010A2 (de)
IL (1) IL159346A0 (de)
MX (1) MXPA04000211A (de)
NO (1) NO20040043L (de)
NZ (1) NZ530473A (de)
PL (1) PL204963B1 (de)
PT (1) PT1275377E (de)
RU (1) RU2288704C2 (de)
WO (1) WO2003005989A2 (de)
ZA (1) ZA200309680B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050080486A1 (en) 2000-11-29 2005-04-14 Fallin T. Wade Facet joint replacement
US6579319B2 (en) 2000-11-29 2003-06-17 Medicinelodge, Inc. Facet joint replacement
US7753937B2 (en) 2003-12-10 2010-07-13 Facet Solutions Inc. Linked bilateral spinal facet implants and methods of use
CA2630304C (en) 2005-12-09 2012-04-10 Teva Pharmaceutical Industries Ltd. Aqueous dispersions and solutions of difficult to dissolve compounds and methods of their preparation
ES2496166T3 (es) * 2006-12-22 2014-09-18 Yuhan Corporation Dispersión sólida que contiene revaprazán y proceso para la preparación de la misma
EP3702442A1 (de) * 2011-12-22 2020-09-02 Life Technologies Corporation Zellkulturmedien und verfahren
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
BR112018070199A2 (pt) 2016-04-01 2019-01-29 Therapeuticsmd Inc composição farmacêutica de hormônio esteroide
EP3641726A1 (de) * 2017-06-23 2020-04-29 MedCan Pharma A/S Cannabinoid-beutel
CN108309933A (zh) * 2018-03-19 2018-07-24 青岛国海生物制药有限公司 一种口服醋酸甲地孕酮纳米混悬液及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3610037A1 (de) * 1986-03-21 1987-09-24 Schering Ag Nifedipinkombinationspraeparat
JPH0449232A (ja) 1990-06-15 1992-02-18 Fujisawa Pharmaceut Co Ltd 懸濁用組成物または懸濁液並びにそれらの製造法
US5338732A (en) 1991-06-18 1994-08-16 Bristol-Myers Squibb Company Megestrol acetate formulation
US5395627A (en) * 1992-09-04 1995-03-07 Akzo N.V. Pharmaceutical granulate
FR2702968B1 (fr) 1993-03-23 1995-06-23 Lafon Labor Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation .
BR9407728A (pt) 1993-10-01 1997-02-12 Syntex Inc Suspensoes orais de altas doses de mofetil de microfenolato
US5976570A (en) * 1993-12-21 1999-11-02 Applied Analytical Industries, Inc. Method for preparing low dose pharmaceutical products
FR2730163B1 (fr) 1995-02-03 1997-04-04 Jouveinal Lab Nouvelle composition pharmaceutique contenant la trimebutine et son procede de preparation
US20020028248A1 (en) 1996-03-14 2002-03-07 Takayuki Tsukada Rapid-release microdispersible ecadotril preparation
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
DE19637082A1 (de) * 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Schnellzerfallende Pellets
TW486370B (en) * 1996-12-25 2002-05-11 Yamanouchi Pharma Co Ltd Rapidly disintegrable pharmaceutical composition
US6028065A (en) * 1998-04-20 2000-02-22 Pharmaceutical Resources, Inc. Flocculated suspension of megestrol acetate
ID29270A (id) 1998-11-20 2001-08-16 Rtp Pharma Inc Partikel-partikel mikro yang distabilkan oleh fosfolipid yang dapat menyebar
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form

Also Published As

Publication number Publication date
CA2452386A1 (en) 2003-01-23
EP1275377A1 (de) 2003-01-15
WO2003005989A2 (en) 2003-01-23
BR0211081A (pt) 2004-12-14
EP1275377B1 (de) 2003-06-18
CA2452386C (en) 2011-01-18
KR100877628B1 (ko) 2009-01-07
PL369294A1 (en) 2005-04-18
PL204963B1 (pl) 2010-02-26
JP2004536118A (ja) 2004-12-02
RU2004103853A (ru) 2005-03-27
MXPA04000211A (es) 2005-03-07
DE60100389T2 (de) 2004-05-19
ZA200309680B (en) 2004-12-22
HRP20040010B1 (de) 2007-01-31
NO20040043L (no) 2004-01-06
US20040009232A1 (en) 2004-01-15
PT1275377E (pt) 2003-11-28
AU2002328866B2 (en) 2007-02-15
IL159346A0 (en) 2004-06-01
NZ530473A (en) 2006-02-24
HRP20040010A2 (en) 2004-06-30
ATE243028T1 (de) 2003-07-15
KR20040018440A (ko) 2004-03-03
US7615547B2 (en) 2009-11-10
ES2199202T3 (es) 2004-02-16
WO2003005989A3 (en) 2003-05-01
RU2288704C2 (ru) 2006-12-10
DK1275377T3 (da) 2003-10-06

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