DE60115090D1 - Verfahren und kit zur erkennung von kinase aktivität - Google Patents
Verfahren und kit zur erkennung von kinase aktivitätInfo
- Publication number
- DE60115090D1 DE60115090D1 DE60115090T DE60115090T DE60115090D1 DE 60115090 D1 DE60115090 D1 DE 60115090D1 DE 60115090 T DE60115090 T DE 60115090T DE 60115090 T DE60115090 T DE 60115090T DE 60115090 D1 DE60115090 D1 DE 60115090D1
- Authority
- DE
- Germany
- Prior art keywords
- atp
- tested
- protein kinase
- kit
- kinase activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0030727 | 2000-12-15 | ||
GBGB0030727.2A GB0030727D0 (en) | 2000-12-15 | 2000-12-15 | Methods and kits for detecting kinase activity |
PCT/GB2001/005506 WO2002048390A2 (en) | 2000-12-15 | 2001-12-13 | Methods and kits for detecting protein kinases |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60115090D1 true DE60115090D1 (de) | 2005-12-22 |
DE60115090T2 DE60115090T2 (de) | 2006-07-13 |
Family
ID=9905234
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60115090T Expired - Lifetime DE60115090T2 (de) | 2000-12-15 | 2001-12-13 | Verfahren und kit zur erkennung von kinase aktivität |
DE10196608T Ceased DE10196608T1 (de) | 2000-12-15 | 2001-12-13 | Verfahren und Kits für den Nachweis von Proteinkinasen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10196608T Ceased DE10196608T1 (de) | 2000-12-15 | 2001-12-13 | Verfahren und Kits für den Nachweis von Proteinkinasen |
Country Status (12)
Country | Link |
---|---|
US (3) | US6599711B2 (de) |
EP (1) | EP1341928B1 (de) |
JP (1) | JP3854927B2 (de) |
AT (1) | ATE310101T1 (de) |
AU (1) | AU2002222193A1 (de) |
CA (1) | CA2431274C (de) |
CH (1) | CH694096A5 (de) |
DE (2) | DE60115090T2 (de) |
DK (1) | DK1341928T3 (de) |
ES (1) | ES2256165T3 (de) |
GB (2) | GB0030727D0 (de) |
WO (1) | WO2002048390A2 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0030727D0 (en) * | 2000-12-15 | 2001-01-31 | Lumitech Uk Ltd | Methods and kits for detecting kinase activity |
JP5155515B2 (ja) * | 2002-09-06 | 2013-03-06 | プロメガ コーポレイション | トランスフェラーゼ酵素活性を検出する方法 |
US7799526B2 (en) | 2002-11-21 | 2010-09-21 | The University Of North Carolina At Chapel Hill | Phosphoprotein detection reagent and methods of making and using the same |
AU2003300008B2 (en) | 2002-12-23 | 2007-04-05 | Promega Corporation | Improved luciferase-based assays |
US7378505B2 (en) * | 2003-01-30 | 2008-05-27 | Bellbrook Labs Llc | Assay method for group transfer reactions |
US7355010B2 (en) * | 2003-01-30 | 2008-04-08 | Bellbrook Labs, Llc | Assay method for group transfer reactions |
CA2514877A1 (en) * | 2003-01-30 | 2004-08-12 | Bellbrook Labs, Llc | Assay method for group transfer reactions |
US8088897B2 (en) * | 2003-01-30 | 2012-01-03 | BellBrook Labs, Inc. | Assay method for group transfer reactions |
CA2445420A1 (en) * | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
DE602004005617T2 (de) * | 2003-12-22 | 2007-12-13 | Alcon Inc. | Mittel zur behandlung von glaukomatöser retinopathie und optischer neuropathie |
CA2548146A1 (en) * | 2003-12-22 | 2005-07-14 | Alcon, Inc. | Agents for treatment of diabetic retinopathy and drusen formation in macular degeneration |
TW200526224A (en) * | 2003-12-22 | 2005-08-16 | Alcon Inc | Short form c-Maf transcription factor antagonists for treatment of glaucoma |
CA2553218A1 (en) | 2004-01-16 | 2005-08-04 | Mds Pharma Services | Fluorescence-based adp detection system |
CN1918305B (zh) * | 2004-02-09 | 2010-12-01 | 扶桑药品工业株式会社 | 核酸检测方法及其应用 |
US20050222127A1 (en) * | 2004-03-30 | 2005-10-06 | Alcon, Inc. | Use of Rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance |
US20060115870A1 (en) * | 2004-03-30 | 2006-06-01 | Alcon, Inc. | High throughput assay for human Rho kinase activity |
US20080096238A1 (en) * | 2004-03-30 | 2008-04-24 | Alcon, Inc. | High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio |
CA2572608A1 (en) * | 2004-07-02 | 2006-08-17 | Promega Corporation | Microbial atp extraction and detection system |
ES2325739T3 (es) * | 2004-11-18 | 2009-09-15 | Saladax Biomedical Inc. | Medicion enzimatica de mesilato de imatinib. |
US7338775B1 (en) | 2005-02-09 | 2008-03-04 | Myriad Genetics, Inc. | Enzyme assay and use thereof |
US20060234323A1 (en) * | 2005-04-18 | 2006-10-19 | Cali James J | Luminescent ATP detection with extended linearity |
US7348159B2 (en) * | 2005-04-20 | 2008-03-25 | Boehringer Ingelheim International Gmbh | Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S |
US9043016B2 (en) * | 2005-10-21 | 2015-05-26 | Deere & Company | Versatile robotic control module |
WO2007093049A1 (en) | 2006-02-13 | 2007-08-23 | Olga Ornatsky | Kinase and phosphatase assays conducted by elemental analysis |
PT2444804E (pt) | 2006-05-27 | 2015-11-25 | Fluidigm Canada Inc | Marcadores elementares da cadeia principal de polímeros |
KR100746961B1 (ko) | 2006-07-31 | 2007-08-07 | 한국과학기술연구원 | 단백질 키나아제 a 검출용 바이오 센서, 및 이를 포함하는키트 |
US20080057531A1 (en) * | 2006-08-07 | 2008-03-06 | Oregon Health And Science University | Systems, kits, and methods for detecting cariogenic bacteria and assessing risk of dental caries |
US7977043B2 (en) * | 2006-11-10 | 2011-07-12 | Boehringer Ingelheim International Gmbh | Assays useful in determining CD38 inhibition |
DE102006059881A1 (de) * | 2006-12-19 | 2008-07-03 | Sanofi-Aventis | Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse |
US8183007B2 (en) | 2008-07-22 | 2012-05-22 | Promega Corporation | ADP detection based methods using adenylate cyclase and bioluminescence |
US20140080161A1 (en) * | 2010-09-14 | 2014-03-20 | Research And Diagnostic Systems, Inc. | Phosphatase coupled kinase assay |
GB201017721D0 (en) * | 2010-10-20 | 2010-12-01 | Queen Mary & Westfield College | Method |
NL2013366B1 (en) | 2014-08-26 | 2016-09-23 | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis | Adenylation enzyme inhibitors. |
US9677117B2 (en) | 2014-10-08 | 2017-06-13 | Promega Corporation | Bioluminescent succinate detection assay |
JP6522556B2 (ja) * | 2015-07-06 | 2019-05-29 | 富士フイルム株式会社 | 血液検査キット、及びそれを用いた分析方法 |
KR101788096B1 (ko) * | 2016-04-12 | 2017-10-19 | 재단법인 한국파스퇴르연구소 | 티아민 모노포스페이트 키나아제를 이용한 항균물질의 스크리닝 키트 및 스크리닝 방법 |
JP7414029B2 (ja) | 2021-02-26 | 2024-01-16 | 横河電機株式会社 | 測定方法及び測定システム |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE428379B (sv) * | 1978-05-31 | 1983-06-27 | Lkb Produkter Ab | Bioluminiscens bestemning av atp och reagens herfor |
DE2828658C3 (de) * | 1978-06-29 | 1981-10-22 | Lkb-Produkter Ab, Stockholm | Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür |
DE2908054A1 (de) * | 1979-03-02 | 1980-09-11 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur bestimmung der creatinkinase |
SE7905852L (sv) * | 1979-07-04 | 1981-01-05 | Lkb Produkter Ab | Forfarande for bestemning av kreatinkinas |
GB2055200B (en) * | 1979-07-24 | 1984-05-02 | Kolehmainen S | Luminescent assays with enzymatic cycling enhancement of the sensitivity of bioluminescent and chemi |
US5583024A (en) | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
DE8533854U1 (de) * | 1985-12-02 | 1986-02-27 | Lewandoske, Herbert, 8620 Lichtenfels | Sitzmöbel, insbesondere Sofa (und Sessel) mit abklappbaren Armlehnen |
US4968613A (en) | 1987-07-29 | 1990-11-06 | Kikkoman Corporation | Luciferase gene and novel recombinant DNA as well as a method of producing luciferase |
US5219737A (en) | 1990-03-27 | 1993-06-15 | Kikkoman Corporation | Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase |
US5374534A (en) | 1990-07-19 | 1994-12-20 | Charm Sciences, Inc. | Method of preparing D-luciferin derivatives |
GB9301118D0 (en) | 1993-01-21 | 1993-03-10 | Secr Defence | Enzyme linked assays |
US5648232A (en) * | 1993-01-21 | 1997-07-15 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Microbiological best method and reagents |
WO1995018853A1 (en) | 1994-01-03 | 1995-07-13 | Promega Corporation | Mutant luciferases |
US6171808B1 (en) | 1995-01-20 | 2001-01-09 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Mutant luciferases |
JP3409962B2 (ja) * | 1996-03-04 | 2003-05-26 | キッコーマン株式会社 | 生物発光試薬及びその試薬を用いたアデノシンリン酸エステルの定量法並びにその試薬を用いたatp変換反応系に関与する物質の定量法 |
US5759795A (en) * | 1996-03-08 | 1998-06-02 | Schering Corporation | Assay for determining inhibitors of ATPase |
US5925558A (en) * | 1996-07-16 | 1999-07-20 | The Regents Of The University Of California | Assays for protein kinases using fluorescent protein substrates |
US5759787A (en) * | 1996-08-26 | 1998-06-02 | Tularik Inc. | Kinase assay |
GB9626932D0 (en) | 1996-12-24 | 1997-02-12 | Lumitech Limited | Assay methods and kits therefor |
GB9707486D0 (en) | 1997-04-11 | 1997-05-28 | Secr Defence | Enzyme assays |
US6310060B1 (en) * | 1998-06-24 | 2001-10-30 | Warner-Lambert Company | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors |
DE69837612T2 (de) | 1997-07-08 | 2007-12-27 | Kikkoman Corp., Noda | Mutiertes bioluminiszenz-protein und verfahren für seine herstellung. |
US6074859A (en) | 1997-07-08 | 2000-06-13 | Kikkoman Corporation | Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein |
ES2262308T3 (es) | 1998-01-21 | 2006-11-16 | The Secretary Of State For Defence | Ensayos de sensibilidad a antibioticos. |
GB9803156D0 (en) | 1998-02-13 | 1998-04-08 | Celsis Int Plc | Assay |
NL1010224C2 (nl) | 1998-09-30 | 2000-03-31 | Packard Biosciene B V | Werkwijze voor het detecteren van ATP. |
DE19901427C1 (de) * | 1999-01-18 | 2000-08-10 | Walter Knoll Gmbh & Co Kg Sitz | Sitzmöbel |
GB9911095D0 (en) | 1999-05-13 | 1999-07-14 | Secr Defence | Microbiological test method and reagents |
GB0030727D0 (en) * | 2000-12-15 | 2001-01-31 | Lumitech Uk Ltd | Methods and kits for detecting kinase activity |
-
2000
- 2000-12-15 GB GBGB0030727.2A patent/GB0030727D0/en not_active Ceased
-
2001
- 2001-12-13 GB GB0129889A patent/GB2375171B/en not_active Expired - Lifetime
- 2001-12-13 DE DE60115090T patent/DE60115090T2/de not_active Expired - Lifetime
- 2001-12-13 AU AU2002222193A patent/AU2002222193A1/en not_active Abandoned
- 2001-12-13 AT AT01270619T patent/ATE310101T1/de active
- 2001-12-13 DK DK01270619T patent/DK1341928T3/da active
- 2001-12-13 ES ES01270619T patent/ES2256165T3/es not_active Expired - Lifetime
- 2001-12-13 WO PCT/GB2001/005506 patent/WO2002048390A2/en active IP Right Grant
- 2001-12-13 JP JP2002550104A patent/JP3854927B2/ja not_active Expired - Fee Related
- 2001-12-13 CA CA2431274A patent/CA2431274C/en not_active Expired - Lifetime
- 2001-12-13 DE DE10196608T patent/DE10196608T1/de not_active Ceased
- 2001-12-13 CH CH00834/03A patent/CH694096A5/de not_active IP Right Cessation
- 2001-12-13 EP EP01270619A patent/EP1341928B1/de not_active Expired - Lifetime
- 2001-12-14 US US10/014,816 patent/US6599711B2/en not_active Expired - Lifetime
-
2003
- 2003-05-01 US US10/426,973 patent/US6911319B2/en not_active Expired - Lifetime
-
2004
- 2004-07-16 US US10/892,285 patent/US20040253658A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20040077030A1 (en) | 2004-04-22 |
ATE310101T1 (de) | 2005-12-15 |
DK1341928T3 (da) | 2006-03-27 |
US20020172991A1 (en) | 2002-11-21 |
EP1341928A2 (de) | 2003-09-10 |
US6911319B2 (en) | 2005-06-28 |
GB0129889D0 (en) | 2002-02-06 |
AU2002222193A1 (en) | 2002-06-24 |
GB0030727D0 (en) | 2001-01-31 |
WO2002048390A3 (en) | 2003-06-26 |
DE10196608T1 (de) | 2003-07-31 |
GB2375171A (en) | 2002-11-06 |
US6599711B2 (en) | 2003-07-29 |
CH694096A5 (de) | 2004-07-15 |
EP1341928B1 (de) | 2005-11-16 |
CA2431274A1 (en) | 2002-06-20 |
JP3854927B2 (ja) | 2006-12-06 |
WO2002048390A2 (en) | 2002-06-20 |
GB2375171B (en) | 2003-03-12 |
JP2004518422A (ja) | 2004-06-24 |
CA2431274C (en) | 2011-05-17 |
US20040253658A1 (en) | 2004-12-16 |
DE60115090T2 (de) | 2006-07-13 |
ES2256165T3 (es) | 2006-07-16 |
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Legal Events
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Ref document number: 1341928 Country of ref document: EP Owner name: LONZA BIOPRODUCTS AG, CH Free format text: FORMER OWNER: CAMBREX BIO SCIENCE NOTTINGHAM LTD., NOTTINGHAM, GB Effective date: 20120926 |
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