DE60115090D1 - Verfahren und kit zur erkennung von kinase aktivität - Google Patents

Verfahren und kit zur erkennung von kinase aktivität

Info

Publication number
DE60115090D1
DE60115090D1 DE60115090T DE60115090T DE60115090D1 DE 60115090 D1 DE60115090 D1 DE 60115090D1 DE 60115090 T DE60115090 T DE 60115090T DE 60115090 T DE60115090 T DE 60115090T DE 60115090 D1 DE60115090 D1 DE 60115090D1
Authority
DE
Germany
Prior art keywords
atp
tested
protein kinase
kit
kinase activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115090T
Other languages
English (en)
Other versions
DE60115090T2 (de
Inventor
Patricia Crouch
John Slater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza Bioproducts Ag Ch
Original Assignee
CAMBREX BIO SCIENCE NOTTINGHAM Ltd NOTTINGHAM
Cambrex Bio Science Nottingham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9905234&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60115090(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by CAMBREX BIO SCIENCE NOTTINGHAM Ltd NOTTINGHAM, Cambrex Bio Science Nottingham Ltd filed Critical CAMBREX BIO SCIENCE NOTTINGHAM Ltd NOTTINGHAM
Publication of DE60115090D1 publication Critical patent/DE60115090D1/de
Application granted granted Critical
Publication of DE60115090T2 publication Critical patent/DE60115090T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
DE60115090T 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität Expired - Lifetime DE60115090T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0030727 2000-12-15
GBGB0030727.2A GB0030727D0 (en) 2000-12-15 2000-12-15 Methods and kits for detecting kinase activity
PCT/GB2001/005506 WO2002048390A2 (en) 2000-12-15 2001-12-13 Methods and kits for detecting protein kinases

Publications (2)

Publication Number Publication Date
DE60115090D1 true DE60115090D1 (de) 2005-12-22
DE60115090T2 DE60115090T2 (de) 2006-07-13

Family

ID=9905234

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60115090T Expired - Lifetime DE60115090T2 (de) 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität
DE10196608T Ceased DE10196608T1 (de) 2000-12-15 2001-12-13 Verfahren und Kits für den Nachweis von Proteinkinasen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10196608T Ceased DE10196608T1 (de) 2000-12-15 2001-12-13 Verfahren und Kits für den Nachweis von Proteinkinasen

Country Status (12)

Country Link
US (3) US6599711B2 (de)
EP (1) EP1341928B1 (de)
JP (1) JP3854927B2 (de)
AT (1) ATE310101T1 (de)
AU (1) AU2002222193A1 (de)
CA (1) CA2431274C (de)
CH (1) CH694096A5 (de)
DE (2) DE60115090T2 (de)
DK (1) DK1341928T3 (de)
ES (1) ES2256165T3 (de)
GB (2) GB0030727D0 (de)
WO (1) WO2002048390A2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0030727D0 (en) * 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity
JP5155515B2 (ja) * 2002-09-06 2013-03-06 プロメガ コーポレイション トランスフェラーゼ酵素活性を検出する方法
US7799526B2 (en) 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
AU2003300008B2 (en) 2002-12-23 2007-04-05 Promega Corporation Improved luciferase-based assays
US7378505B2 (en) * 2003-01-30 2008-05-27 Bellbrook Labs Llc Assay method for group transfer reactions
US7355010B2 (en) * 2003-01-30 2008-04-08 Bellbrook Labs, Llc Assay method for group transfer reactions
CA2514877A1 (en) * 2003-01-30 2004-08-12 Bellbrook Labs, Llc Assay method for group transfer reactions
US8088897B2 (en) * 2003-01-30 2012-01-03 BellBrook Labs, Inc. Assay method for group transfer reactions
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
DE602004005617T2 (de) * 2003-12-22 2007-12-13 Alcon Inc. Mittel zur behandlung von glaukomatöser retinopathie und optischer neuropathie
CA2548146A1 (en) * 2003-12-22 2005-07-14 Alcon, Inc. Agents for treatment of diabetic retinopathy and drusen formation in macular degeneration
TW200526224A (en) * 2003-12-22 2005-08-16 Alcon Inc Short form c-Maf transcription factor antagonists for treatment of glaucoma
CA2553218A1 (en) 2004-01-16 2005-08-04 Mds Pharma Services Fluorescence-based adp detection system
CN1918305B (zh) * 2004-02-09 2010-12-01 扶桑药品工业株式会社 核酸检测方法及其应用
US20050222127A1 (en) * 2004-03-30 2005-10-06 Alcon, Inc. Use of Rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
US20060115870A1 (en) * 2004-03-30 2006-06-01 Alcon, Inc. High throughput assay for human Rho kinase activity
US20080096238A1 (en) * 2004-03-30 2008-04-24 Alcon, Inc. High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio
CA2572608A1 (en) * 2004-07-02 2006-08-17 Promega Corporation Microbial atp extraction and detection system
ES2325739T3 (es) * 2004-11-18 2009-09-15 Saladax Biomedical Inc. Medicion enzimatica de mesilato de imatinib.
US7338775B1 (en) 2005-02-09 2008-03-04 Myriad Genetics, Inc. Enzyme assay and use thereof
US20060234323A1 (en) * 2005-04-18 2006-10-19 Cali James J Luminescent ATP detection with extended linearity
US7348159B2 (en) * 2005-04-20 2008-03-25 Boehringer Ingelheim International Gmbh Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S
US9043016B2 (en) * 2005-10-21 2015-05-26 Deere & Company Versatile robotic control module
WO2007093049A1 (en) 2006-02-13 2007-08-23 Olga Ornatsky Kinase and phosphatase assays conducted by elemental analysis
PT2444804E (pt) 2006-05-27 2015-11-25 Fluidigm Canada Inc Marcadores elementares da cadeia principal de polímeros
KR100746961B1 (ko) 2006-07-31 2007-08-07 한국과학기술연구원 단백질 키나아제 a 검출용 바이오 센서, 및 이를 포함하는키트
US20080057531A1 (en) * 2006-08-07 2008-03-06 Oregon Health And Science University Systems, kits, and methods for detecting cariogenic bacteria and assessing risk of dental caries
US7977043B2 (en) * 2006-11-10 2011-07-12 Boehringer Ingelheim International Gmbh Assays useful in determining CD38 inhibition
DE102006059881A1 (de) * 2006-12-19 2008-07-03 Sanofi-Aventis Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse
US8183007B2 (en) 2008-07-22 2012-05-22 Promega Corporation ADP detection based methods using adenylate cyclase and bioluminescence
US20140080161A1 (en) * 2010-09-14 2014-03-20 Research And Diagnostic Systems, Inc. Phosphatase coupled kinase assay
GB201017721D0 (en) * 2010-10-20 2010-12-01 Queen Mary & Westfield College Method
NL2013366B1 (en) 2014-08-26 2016-09-23 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Adenylation enzyme inhibitors.
US9677117B2 (en) 2014-10-08 2017-06-13 Promega Corporation Bioluminescent succinate detection assay
JP6522556B2 (ja) * 2015-07-06 2019-05-29 富士フイルム株式会社 血液検査キット、及びそれを用いた分析方法
KR101788096B1 (ko) * 2016-04-12 2017-10-19 재단법인 한국파스퇴르연구소 티아민 모노포스페이트 키나아제를 이용한 항균물질의 스크리닝 키트 및 스크리닝 방법
JP7414029B2 (ja) 2021-02-26 2024-01-16 横河電機株式会社 測定方法及び測定システム

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE428379B (sv) * 1978-05-31 1983-06-27 Lkb Produkter Ab Bioluminiscens bestemning av atp och reagens herfor
DE2828658C3 (de) * 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
DE2908054A1 (de) * 1979-03-02 1980-09-11 Boehringer Mannheim Gmbh Verfahren und reagenz zur bestimmung der creatinkinase
SE7905852L (sv) * 1979-07-04 1981-01-05 Lkb Produkter Ab Forfarande for bestemning av kreatinkinas
GB2055200B (en) * 1979-07-24 1984-05-02 Kolehmainen S Luminescent assays with enzymatic cycling enhancement of the sensitivity of bioluminescent and chemi
US5583024A (en) 1985-12-02 1996-12-10 The Regents Of The University Of California Recombinant expression of Coleoptera luciferase
DE8533854U1 (de) * 1985-12-02 1986-02-27 Lewandoske, Herbert, 8620 Lichtenfels Sitzmöbel, insbesondere Sofa (und Sessel) mit abklappbaren Armlehnen
US4968613A (en) 1987-07-29 1990-11-06 Kikkoman Corporation Luciferase gene and novel recombinant DNA as well as a method of producing luciferase
US5219737A (en) 1990-03-27 1993-06-15 Kikkoman Corporation Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase
US5374534A (en) 1990-07-19 1994-12-20 Charm Sciences, Inc. Method of preparing D-luciferin derivatives
GB9301118D0 (en) 1993-01-21 1993-03-10 Secr Defence Enzyme linked assays
US5648232A (en) * 1993-01-21 1997-07-15 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Microbiological best method and reagents
WO1995018853A1 (en) 1994-01-03 1995-07-13 Promega Corporation Mutant luciferases
US6171808B1 (en) 1995-01-20 2001-01-09 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Mutant luciferases
JP3409962B2 (ja) * 1996-03-04 2003-05-26 キッコーマン株式会社 生物発光試薬及びその試薬を用いたアデノシンリン酸エステルの定量法並びにその試薬を用いたatp変換反応系に関与する物質の定量法
US5759795A (en) * 1996-03-08 1998-06-02 Schering Corporation Assay for determining inhibitors of ATPase
US5925558A (en) * 1996-07-16 1999-07-20 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
US5759787A (en) * 1996-08-26 1998-06-02 Tularik Inc. Kinase assay
GB9626932D0 (en) 1996-12-24 1997-02-12 Lumitech Limited Assay methods and kits therefor
GB9707486D0 (en) 1997-04-11 1997-05-28 Secr Defence Enzyme assays
US6310060B1 (en) * 1998-06-24 2001-10-30 Warner-Lambert Company 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
DE69837612T2 (de) 1997-07-08 2007-12-27 Kikkoman Corp., Noda Mutiertes bioluminiszenz-protein und verfahren für seine herstellung.
US6074859A (en) 1997-07-08 2000-06-13 Kikkoman Corporation Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein
ES2262308T3 (es) 1998-01-21 2006-11-16 The Secretary Of State For Defence Ensayos de sensibilidad a antibioticos.
GB9803156D0 (en) 1998-02-13 1998-04-08 Celsis Int Plc Assay
NL1010224C2 (nl) 1998-09-30 2000-03-31 Packard Biosciene B V Werkwijze voor het detecteren van ATP.
DE19901427C1 (de) * 1999-01-18 2000-08-10 Walter Knoll Gmbh & Co Kg Sitz Sitzmöbel
GB9911095D0 (en) 1999-05-13 1999-07-14 Secr Defence Microbiological test method and reagents
GB0030727D0 (en) * 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity

Also Published As

Publication number Publication date
US20040077030A1 (en) 2004-04-22
ATE310101T1 (de) 2005-12-15
DK1341928T3 (da) 2006-03-27
US20020172991A1 (en) 2002-11-21
EP1341928A2 (de) 2003-09-10
US6911319B2 (en) 2005-06-28
GB0129889D0 (en) 2002-02-06
AU2002222193A1 (en) 2002-06-24
GB0030727D0 (en) 2001-01-31
WO2002048390A3 (en) 2003-06-26
DE10196608T1 (de) 2003-07-31
GB2375171A (en) 2002-11-06
US6599711B2 (en) 2003-07-29
CH694096A5 (de) 2004-07-15
EP1341928B1 (de) 2005-11-16
CA2431274A1 (en) 2002-06-20
JP3854927B2 (ja) 2006-12-06
WO2002048390A2 (en) 2002-06-20
GB2375171B (en) 2003-03-12
JP2004518422A (ja) 2004-06-24
CA2431274C (en) 2011-05-17
US20040253658A1 (en) 2004-12-16
DE60115090T2 (de) 2006-07-13
ES2256165T3 (es) 2006-07-16

Similar Documents

Publication Publication Date Title
ATE310101T1 (de) Verfahren und kit zur erkennung von kinase aktivität
ATE431427T1 (de) Verbessertes verfahren zum nachweis von atp
WO2005028624A3 (en) Molecular scaffolds for kinase ligand development
CY1110515T1 (el) Προσδιορισμος αλληλεπιδρασεων ενωσης-πρωτεϊνης με χρηση βιβλιοθηκων μοριων συντηξης πρωτεϊνης-νουκλεϊκου οξεος
GB2430740A (en) System and method for tracking and quatitating chemical entites
ATE383442T1 (de) Verfahren zur sequenzierung von polynukleotiden
ATE426041T1 (de) Zirkulare sonden amplifizierung (cpa) von zirkularisierten nucleinsaure-molekulen
ATE316147T1 (de) Enzymsensor
DE60239748D1 (de) Verfahren, gerät und vorrichtung zur konzentrationsmessung
DE69028247T2 (de) Verfahren zur Messung von Bestandteilen einer Körperflüssigkeit
ATE347105T1 (de) Verfahren, assay und kit zur quantifizierung von hiv-proteasehemmer
DE60029413D1 (de) Enzymatische messung von mycophenolsäure
ATE384139T1 (de) Multi-test-analyse von echzeit- nukleinsäureamplifikationen
ATE487797T1 (de) Verfahren zum nachweis von transferase- enzymaktivität
FI95485C (fi) Määritysmenetelmä ja materiaalisarja nesteessä olevan entsyymin määrittämiseksi
DE3473475D1 (en) Process for determining substrate or enzymatic activity
ATE440964T1 (de) Verfahren zur detektion von polynukleotidkinase und deren verwendung als markierung
DE60131281D1 (de) Verfahren zum messen von gesamt-homocystein
KR890008327A (ko) 효소 역학의 자동측정 방법
ATE359513T1 (de) Hochdurchsatzscreening von verbindungen für biologische wirksamkeit
DE60016391D1 (de) Verfahren zur untersuchung einer biologischen flüssigkeit
SE0202454D0 (sv) Method and apparatus
ATE434668T1 (de) Methode zur messung von amylase aktivität
Vootukuri Reddy et al. Retaining in‐gel zymographic activity of cysteine proteases via a cysteine‐supplemented running buffer
DE50111741D1 (de) Verfahren zur durchführung einer chemischen reaktion

Legal Events

Date Code Title Description
R082 Change of representative

Ref document number: 1341928

Country of ref document: EP

Representative=s name: ANDRAE FLACH HAUG, DE

R081 Change of applicant/patentee

Ref document number: 1341928

Country of ref document: EP

Owner name: LONZA BIOPRODUCTS AG, CH

Free format text: FORMER OWNER: CAMBREX BIO SCIENCE NOTTINGHAM LTD., NOTTINGHAM, GB

Effective date: 20120926

R082 Change of representative

Ref document number: 1341928

Country of ref document: EP

Representative=s name: ANDRAE FLACH HAUG, DE

Effective date: 20120926