DE60115203D1 - Beschichtete implantate - Google Patents

Beschichtete implantate

Info

Publication number
DE60115203D1
DE60115203D1 DE60115203T DE60115203T DE60115203D1 DE 60115203 D1 DE60115203 D1 DE 60115203D1 DE 60115203 T DE60115203 T DE 60115203T DE 60115203 T DE60115203 T DE 60115203T DE 60115203 D1 DE60115203 D1 DE 60115203D1
Authority
DE
Germany
Prior art keywords
polymer
stent
meth
acrylate
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115203T
Other languages
English (en)
Other versions
DE60115203T2 (de
Inventor
Gerald Hughes
Terrence Albert Vick
Jin Hai Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocompatibles UK Ltd
Original Assignee
Biocompatibles UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocompatibles UK Ltd filed Critical Biocompatibles UK Ltd
Application granted granted Critical
Publication of DE60115203D1 publication Critical patent/DE60115203D1/de
Publication of DE60115203T2 publication Critical patent/DE60115203T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers
DE60115203T 2000-01-24 2001-01-24 Beschichtete implantate Expired - Lifetime DE60115203T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00300509 2000-01-24
EP00300509 2000-01-24
PCT/GB2001/000281 WO2001052915A1 (en) 2000-01-24 2001-01-24 Coated implants

Publications (2)

Publication Number Publication Date
DE60115203D1 true DE60115203D1 (de) 2005-12-29
DE60115203T2 DE60115203T2 (de) 2006-08-03

Family

ID=8172662

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115203T Expired - Lifetime DE60115203T2 (de) 2000-01-24 2001-01-24 Beschichtete implantate

Country Status (7)

Country Link
US (2) US6746686B2 (de)
EP (1) EP1250164B1 (de)
JP (1) JP5000826B2 (de)
AT (1) ATE310542T1 (de)
AU (1) AU2001228653A1 (de)
DE (1) DE60115203T2 (de)
WO (1) WO2001052915A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208010B2 (en) * 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6241762B1 (en) 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US20040254635A1 (en) 1998-03-30 2004-12-16 Shanley John F. Expandable medical device for delivery of beneficial agent
US6872225B1 (en) * 1999-05-27 2005-03-29 Biocompatibles Uk Limited Local drug delivery
DE20122506U1 (de) 2000-10-16 2005-12-08 Conor Medsystems, Inc., Menlo Park Ausdehnbare medizinische Vorrichtung zur Abgabe eines nützlichen Agens
GB0100761D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
US20040204756A1 (en) * 2004-02-11 2004-10-14 Diaz Stephen Hunter Absorbent article with improved liquid acquisition capacity
US20040073294A1 (en) 2002-09-20 2004-04-15 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
US7682669B1 (en) * 2001-07-30 2010-03-23 Advanced Cardiovascular Systems, Inc. Methods for covalently immobilizing anti-thrombogenic material into a coating on a medical device
US20040249443A1 (en) * 2001-08-20 2004-12-09 Shanley John F. Expandable medical device for treating cardiac arrhythmias
US20040137066A1 (en) * 2001-11-26 2004-07-15 Swaminathan Jayaraman Rationally designed therapeutic intravascular implant coating
US20030050648A1 (en) 2001-09-11 2003-03-13 Spiration, Inc. Removable lung reduction devices, systems, and methods
US6592594B2 (en) 2001-10-25 2003-07-15 Spiration, Inc. Bronchial obstruction device deployment system and method
IL162734A0 (en) 2002-02-01 2005-11-20 Ariad Gene Therapeutics Inc Phosphorus-containing compounds & uses thereof
US6929637B2 (en) 2002-02-21 2005-08-16 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US20060235432A1 (en) * 2002-02-21 2006-10-19 Devore Lauri J Intra-bronchial obstructing device that controls biological interaction with the patient
US20030181922A1 (en) 2002-03-20 2003-09-25 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US20030216769A1 (en) 2002-05-17 2003-11-20 Dillard David H. Removable anchored lung volume reduction devices and methods
US7758636B2 (en) * 2002-09-20 2010-07-20 Innovational Holdings Llc Expandable medical device with openings for delivery of multiple beneficial agents
EP1560613A1 (de) * 2002-11-08 2005-08-10 Conor Medsystems, Inc. Verfahren und apparate zur verminderung postischämischer gewebeschädigungen
CA2505576A1 (en) * 2002-11-08 2004-05-27 Conor Medsystems, Inc. Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor
US20050079199A1 (en) * 2003-02-18 2005-04-14 Medtronic, Inc. Porous coatings for drug release from medical devices
US20050010170A1 (en) * 2004-02-11 2005-01-13 Shanley John F Implantable medical device with beneficial agent concentration gradient
EP1610823B1 (de) * 2003-03-28 2011-09-28 Innovational Holdings, LLC Implantierbares medizinprodukt mit kontinuierlichem mittel-konzentrationsgefälle
US7100616B2 (en) 2003-04-08 2006-09-05 Spiration, Inc. Bronchoscopic lung volume reduction method
US7533671B2 (en) 2003-08-08 2009-05-19 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
WO2005027991A1 (en) * 2003-09-19 2005-03-31 Cambridge University Technical Services Ltd Orthopaedic devices
US7785653B2 (en) 2003-09-22 2010-08-31 Innovational Holdings Llc Method and apparatus for loading a beneficial agent into an expandable medical device
US20050100577A1 (en) * 2003-11-10 2005-05-12 Parker Theodore L. Expandable medical device with beneficial agent matrix formed by a multi solvent system
WO2005075003A1 (en) * 2004-01-21 2005-08-18 Medtronic Vascular Inc. Implantable medical devices for treating or preventing restenosis
US20050208093A1 (en) 2004-03-22 2005-09-22 Thierry Glauser Phosphoryl choline coating compositions
US20050287287A1 (en) * 2004-06-24 2005-12-29 Parker Theodore L Methods and systems for loading an implantable medical device with beneficial agent
GB2420976B (en) * 2004-11-19 2006-12-20 Zvi Finkelstein Therapeutic implant
US9101949B2 (en) 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US7896539B2 (en) 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
US20070048349A1 (en) * 2005-08-29 2007-03-01 Bausch & Lomb Incorporated Surface-modified medical devices and methods of making
US7691151B2 (en) 2006-03-31 2010-04-06 Spiration, Inc. Articulable Anchor
US8568764B2 (en) 2006-05-31 2013-10-29 Advanced Cardiovascular Systems, Inc. Methods of forming coating layers for medical devices utilizing flash vaporization
US20080097588A1 (en) * 2006-10-18 2008-04-24 Conor Medsystems, Inc. Systems and Methods for Producing a Medical Device
EP2095018A1 (de) * 2006-12-04 2009-09-02 Cree Led Lighting Solutions, Inc. Beleuchtungsvorrichtung und beleuchtungsverfahren
WO2008130650A1 (en) * 2007-04-19 2008-10-30 University Of Massachusetts Medical School Thermal responsive polymer siloxanes, compositions, and methods and applications related thereto
US8802184B2 (en) * 2007-05-30 2014-08-12 Abbott Cardiovascular Systems Inc. Medical devices containing biobeneficial particles
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
JP5570993B2 (ja) 2007-10-12 2014-08-13 スピレーション インコーポレイテッド 弁装填具の方法、システム、および装置
US8043301B2 (en) 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
US8679571B2 (en) 2008-04-09 2014-03-25 Alexander Rübben Method for producing a bioactive surface on an endoprosthesis or on the balloon of a balloon catheter
WO2010141729A1 (en) 2009-06-03 2010-12-09 Forsight Labs, Llc Anterior segment drug delivery
EP2380602B1 (de) * 2010-04-14 2015-04-22 Hans Kosak Kunststoffe enthaltend Nukleinsäuren in komplexierter Form und Verfahren zu deren Herstellung
US9295747B2 (en) 2010-10-20 2016-03-29 Nof Corporation Contact lens care preparation and packaging solution
US8795241B2 (en) 2011-05-13 2014-08-05 Spiration, Inc. Deployment catheter
CN106073986B (zh) 2011-09-14 2019-01-11 弗赛特影像5股份有限公司 治疗患者的眼睛的装置
WO2013053483A1 (de) 2011-10-11 2013-04-18 Secutech International Pte. Ltd. Verfahren zur herstellung von kunststoffen enthaltend nukleinsäuren in komplexierter form
CN104272174B (zh) * 2012-03-02 2016-01-27 日油株式会社 隐形眼镜用护理制剂及包装溶液
WO2014066775A1 (en) 2012-10-26 2014-05-01 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
JP6111052B2 (ja) * 2012-11-22 2017-04-05 国立大学法人 東京大学 耐汚染性を付与するための水溶性表面処理剤、および表面処理方法
US10597540B2 (en) 2013-05-27 2020-03-24 Jsr Corporation Surface treatment agent for surface configured from inorganic material, tool and device having modified surface, and method for manufacturing tool and device
CN105263995B (zh) 2013-06-20 2019-05-28 住友橡胶工业株式会社 表面改性方法和表面改性体
JP6008213B2 (ja) * 2014-08-06 2016-10-19 リューベン，アレクサンダー 体内プロテーゼ上又はバルーンカテーテルのバルーン上の生体活性表面の製造方法
JP6371165B2 (ja) 2014-09-02 2018-08-08 住友ゴム工業株式会社 金属医療用具
WO2016168141A1 (en) 2015-04-13 2016-10-20 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
JP6613692B2 (ja) 2015-08-03 2019-12-04 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
CA3027200A1 (en) 2016-06-13 2017-12-21 Massachusetts Institute Of Technology Biocompatible zwitterionic polymer coatings and hydrogels for reducing foreign body response and fibrosis

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674192A (en) 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
CA2313676C (en) 1991-07-05 2006-10-10 Biocompatibles Limited Polymeric surface coatings
ATE270310T1 (de) 1991-08-08 2004-07-15 Biocompatibles Uk Ltd Polymere oberflächenbeschichtungszusammensetzungen
US5342621A (en) 1992-09-15 1994-08-30 Advanced Cardiovascular Systems, Inc. Antithrombogenic surface
KR100316205B1 (ko) 1993-01-07 2002-04-24 아브람 엠. 골드핑거 평활근세포의증식을조절하기위한c-myc의안티센스억제
JP3482209B2 (ja) 1994-03-18 2003-12-22 ジェロン・コーポレーション オリゴヌクレオチドｎ３’→ｐ５’ホスホルアミデート：合成および化合物；ハイブリダイゼーションおよびヌクレアーゼ耐性特性
US6090618A (en) * 1996-10-07 2000-07-18 Arch Development Corporation DNA constructs and viral vectors comprising a smooth muscle promoter
US5876433A (en) 1996-05-29 1999-03-02 Ethicon, Inc. Stent and method of varying amounts of heparin coated thereon to control treatment
WO1997047253A1 (en) 1996-06-14 1997-12-18 Kriton Medical, Inc. Methods and devices for reducing angina, enhancing myocardial perfusion and increasing cardiac function
GB9624130D0 (en) 1996-11-20 1997-01-08 Biocompatibles Ltd Biocompatible compositions
JP4422215B2 (ja) 1997-02-20 2010-02-24 クック インコーポレイテッド 被覆された移植可能な医療器具
DE19713214A1 (de) * 1997-03-28 1998-12-10 Ruebben Alexander Dr Med Covered Stent zur verlängerten Offenhaltung von Hohlorganen oder der Behandlung von Gefäßaneurysmen
US6776792B1 (en) 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
US6221425B1 (en) * 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
WO1999055396A1 (en) * 1998-04-27 1999-11-04 Surmodics, Inc. Bioactive agent release coating
US6872225B1 (en) 1999-05-27 2005-03-29 Biocompatibles Uk Limited Local drug delivery

Also Published As

Publication number Publication date
AU2001228653A1 (en) 2001-07-31
EP1250164A1 (de) 2002-10-23
DE60115203T2 (de) 2006-08-03
WO2001052915A1 (en) 2001-07-26
JP5000826B2 (ja) 2012-08-15
US6746686B2 (en) 2004-06-08
US20040197585A1 (en) 2004-10-07
EP1250164B1 (de) 2005-11-23
JP2003520107A (ja) 2003-07-02
US20030086957A1 (en) 2003-05-08
ATE310542T1 (de) 2005-12-15

Similar Documents

Publication Publication Date Title
DE60115203D1 (de) Beschichtete implantate
GB0100761D0 (en) Drug delivery from stents
WO1998029095A3 (en) Sustained release cisapride mini-tablet formulation
EP0636366A3 (de) Mit wässrigen Dispersionen aus Acrylpolymere umgehüllte Formulierungen zur kontrollierten Freigabe
WO2001030408A3 (en) Adhesive composition over a bioactive polymerization initiator
CA2236182A1 (en) Drug-releasing coatings for medical devices
EP1166866A3 (de) Eingekapselte Chemikalien zur Verwendung in zeitverzögerter und kontrollierter Abgabe
ATE391496T1 (de) Geschmacksmaskierte pharmazeutische formulierungen
RU92004344A (ru) Устойчивые лекарственные формы с регулируемым выделением, имеющие акриловые полимерные покрытия, и способ их получения
AU4941400A (en) Local drug delivery
DE69635481D1 (de) Auslösbares wirkstoffabgabesystem
ATE345781T1 (de) Drei verschiedene polymertypen enthaltende formulierung mit verzögerter freigabe
DE69832092D1 (de) VERBESSERTE HMG CoA REDUKTASE-INHIBITOR FORMULIERUNG MIT VERLÄNGERTER FREISETZUNG
NO982764L (no) Oppfinnelse og anordning for transdermal anordning for avgivelse av flurbiprofen
PT1028707E (pt) Formulacoes oftalmicas de libertacao controlada contendo medicamentos soluveis em agua
EP1076239A3 (de) Beschichtung mit quervernetzten hydrophilen Polymeren
EP0640337A3 (de) Arzneimittel mit gesteuertem Beginn und gesteuerter Rate der Freisetzung
ES2172664T3 (es) Punta de aplicador impregnada.
CA2019410A1 (en) Liquid polymer composition, and method of use
EP1321130A3 (de) Haarzusammensetzung enthaltend (Meth)acrylatcopolymere für die umformbare Haarformung
TNSN01123A1 (fr) Formes posologiques nouvelles a liberation controlee
WO2002024174A3 (en) Sustained release composition containing clarithromycin
CA2338070A1 (en) Diltiazem controlled release formulation and method of manufacture
CY1109042T1 (el) Συνθεσεις ομοιοπολικως-συνδεδεμενης υδροφιλης επικαλυψης για εμφυτευματα
ATE167201T1 (de) Polymeroberflächenbeschichtungszusammensetzung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition