DE60136293D1 - Vorrichtung zum abliefern von pharmazeutika an das innenohr - Google Patents

Vorrichtung zum abliefern von pharmazeutika an das innenohr

Info

Publication number
DE60136293D1
DE60136293D1 DE60136293T DE60136293T DE60136293D1 DE 60136293 D1 DE60136293 D1 DE 60136293D1 DE 60136293 T DE60136293 T DE 60136293T DE 60136293 T DE60136293 T DE 60136293T DE 60136293 D1 DE60136293 D1 DE 60136293D1
Authority
DE
Germany
Prior art keywords
inner ear
delivering pharmaceuticals
recipient
elongate member
pharmaceuticals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60136293T
Other languages
English (en)
Inventor
Peter Gibson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cochlear Ltd
Original Assignee
Cochlear Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cochlear Ltd filed Critical Cochlear Ltd
Application granted granted Critical
Publication of DE60136293D1 publication Critical patent/DE60136293D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0541Cochlear electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36036Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the outer, middle or inner ear
    • A61N1/36038Cochlear stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/05General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/054General characteristics of the apparatus combined with other kinds of therapy with electrotherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0662Ears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0662Ears
    • A61M2210/0668Middle ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0662Ears
    • A61M2210/0675Eustachian tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49002Electrical device making
    • Y10T29/49117Conductor or circuit manufacturing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining
    • Y10T29/49885Assembling or joining with coating before or during assembling

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Prostheses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Materials For Medical Uses (AREA)
  • Neurology (AREA)
DE60136293T 2000-11-14 2001-11-14 Vorrichtung zum abliefern von pharmazeutika an das innenohr Expired - Lifetime DE60136293D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPR1484A AUPR148400A0 (en) 2000-11-14 2000-11-14 Apparatus for delivery of pharmaceuticals to the cochlea
PCT/AU2001/001479 WO2002041666A1 (en) 2000-11-14 2001-11-14 Apparatus for delivery of pharmaceuticals to the cochlea

Publications (1)

Publication Number Publication Date
DE60136293D1 true DE60136293D1 (de) 2008-12-04

Family

ID=3825525

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60136293T Expired - Lifetime DE60136293D1 (de) 2000-11-14 2001-11-14 Vorrichtung zum abliefern von pharmazeutika an das innenohr

Country Status (8)

Country Link
US (5) US7571012B2 (de)
EP (1) EP1340408B1 (de)
JP (1) JP4065775B2 (de)
AT (1) ATE411833T1 (de)
AU (2) AUPR148400A0 (de)
CA (1) CA2428542A1 (de)
DE (1) DE60136293D1 (de)
WO (1) WO2002041666A1 (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2392996A1 (en) 2000-10-04 2002-04-11 Cochlear Limited Combination stylet and straightening coating for a cochlear implant electrode array
AU777272B2 (en) 2000-10-04 2004-10-07 Cochlear Limited Cochlear implant electrode array
DE60113293T2 (de) * 2000-10-11 2006-06-29 Cochlear Ltd., Lane Cove Cochlearimplantatelektrodenanordnung mit Doppelstilletteinführgrät
US7894916B2 (en) * 2000-10-17 2011-02-22 Cochlear Limited Insertion tool for a cochlear implant electrode array
AUPR148400A0 (en) 2000-11-14 2000-12-07 Cochlear Limited Apparatus for delivery of pharmaceuticals to the cochlea
US9089450B2 (en) * 2000-11-14 2015-07-28 Cochlear Limited Implantatable component having an accessible lumen and a drug release capsule for introduction into same
US20070088335A1 (en) * 2001-10-24 2007-04-19 Med-El Elektromedizinische Geraete Gmbh Implantable neuro-stimulation electrode with fluid reservoir
AU2002363103B2 (en) * 2001-10-24 2008-10-16 Med-El Elektromedizinische Gerate Ges.M.B.H. Implantable fluid delivery apparatuses and implantable electrode
AUPR879201A0 (en) 2001-11-09 2001-12-06 Cochlear Limited Subthreshold stimulation of a cochlea
US20100030130A1 (en) * 2001-11-09 2010-02-04 Cochlear Limited Pharmaceutical intervention for modulation of neural plasticity
AUPS081502A0 (en) 2002-02-28 2002-03-21 Cochlear Limited Connector for drug delivery system
AU2003275182A1 (en) * 2002-09-19 2004-04-08 Advanced Bionics Corporation Cochlear implant electrode and method of making same
US7319906B2 (en) * 2002-09-19 2008-01-15 Advanced Bionics Corporation Cochlear implant electrode and method of making same
US7349741B2 (en) * 2002-10-11 2008-03-25 Advanced Bionics, Llc Cochlear implant sound processor with permanently integrated replenishable power source
AT507045B1 (de) * 2002-11-29 2010-04-15 Cochlear Ltd Implantierbare, gewebe-stimulierende vorrichtung
US8811643B2 (en) 2003-05-08 2014-08-19 Advanced Bionics Integrated cochlear implant headpiece
EP1684861B1 (de) 2003-10-21 2014-12-03 The Regents Of The University Of Michigan Intrakranielles neurales schnittstellensystem
US20050209664A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Electrical devices and anti-scarring agents
CA2536188A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Electrical devices and anti-scarring agents
AU2004298073B2 (en) * 2003-12-10 2011-11-24 The Bionic Ear Institute Delayed stimulation in auditory prostheses
WO2005057983A1 (en) * 2003-12-10 2005-06-23 The Bionic Ear Institute Delayed stimulation in auditory prostheses
WO2006040690A2 (en) * 2004-03-15 2006-04-20 Med-El Elektromedizinische Geraete Gmbh Cochlear implant electrode with adjustable subdivision for middle ear functions
US7949412B1 (en) 2005-06-02 2011-05-24 Advanced Bionics, Llc Coated electrode array having uncoated electrode contacts
US9014796B2 (en) 2005-06-14 2015-04-21 Regents Of The University Of Michigan Flexible polymer microelectrode with fluid delivery capability and methods for making same
US9265933B2 (en) 2005-09-08 2016-02-23 Massachusetts Eye And Ear Infirmary Cochlear implants containing biological cells and uses thereof
WO2007089738A2 (en) 2006-01-26 2007-08-09 The Regents Of The University Of Michigan Microelectrode with laterally extending platform for reduction of tissue encapsulation
AR059786A1 (es) * 2006-03-09 2008-04-30 Med El Elektromed Geraete Gmbh Configuracion de electrodo de implante coclear para eluir farmacos
US9026205B2 (en) 2006-05-25 2015-05-05 Cochlear Limited Stimulating device
WO2008033791A1 (en) * 2006-09-12 2008-03-20 Med-El Elektromedizinische Geraete Gmbh Middle ear fixation structure
US8731673B2 (en) 2007-02-26 2014-05-20 Sapiens Steering Brain Stimulation B.V. Neural interface system
US20090043369A1 (en) * 2007-06-01 2009-02-12 Med-El Elektromedizinische Geraete Gmbh Flexible Biodegradable Coating For Implantable Medical Devices
US8133215B2 (en) 2007-08-13 2012-03-13 Cochlear Limited Independently-manufactured drug delivery module and corresponding receptacle in an implantable medical device
WO2009029866A2 (en) * 2007-08-29 2009-03-05 Advanced Bionics, Llc Minimizing trauma during and after insertion of a cochlear lead
US20130079749A1 (en) * 2007-08-29 2013-03-28 Advanced Bionics, Llc Modular Drug Delivery System for Minimizing Trauma During and After Insertion of a Cochlear Lead
US8271101B2 (en) 2007-08-29 2012-09-18 Advanced Bionics Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead
WO2009052425A1 (en) 2007-10-17 2009-04-23 Neuronexus Technologies Implantable device including a resorbable carrier
US8224417B2 (en) 2007-10-17 2012-07-17 Neuronexus Technologies, Inc. Guide tube for an implantable device system
US8498720B2 (en) 2008-02-29 2013-07-30 Neuronexus Technologies, Inc. Implantable electrode and method of making the same
US8526641B2 (en) * 2008-03-31 2013-09-03 Cochlear Limited Customizable mass arrangements for bone conduction devices
CN102006907B (zh) * 2008-06-03 2013-10-30 Med-El电气医疗器械有限公司 带感应耦合的植入物的导电涂层
US8144909B2 (en) 2008-08-12 2012-03-27 Cochlear Limited Customization of bone conduction hearing devices
EP2711031A3 (de) * 2008-09-22 2014-07-02 Boston Scientific Neuromodulation Corporation Implantierbare oder einführbare medizinische Vorrichtungen
EP2358427B1 (de) * 2008-10-08 2014-01-15 Med-El Elektromedizinische Geräte GmbH Kochleargewebeschutz vor elektrodentrauma
CN102186528B (zh) * 2008-10-15 2013-08-07 Med-El电气医疗器械有限公司 内耳给药装置
CN102209574A (zh) * 2008-11-10 2011-10-05 Med-El电气医疗器械有限公司 植入型和再装填型的药物递送储存器
US8880193B1 (en) 2009-05-22 2014-11-04 Advanced Bionics, Llc Cochlear electrode array
US8712554B2 (en) * 2009-07-21 2014-04-29 Advanced Bionics Integrated wire carrier for electrode array
US20110160609A1 (en) * 2009-12-29 2011-06-30 Stone Robert T Method and system for monitoring pressure in a body cavity
US8617097B2 (en) 2010-05-24 2013-12-31 Cochlear Limited Drug-delivery accessory for an implantable medical device
US9033869B2 (en) 2010-05-27 2015-05-19 Advanced Bionics, Llc Cochlear lead
US9037267B2 (en) 2010-05-27 2015-05-19 Advanced Bionics Llc Cochlear lead
US8946046B1 (en) 2012-05-02 2015-02-03 Crossbar, Inc. Guided path for forming a conductive filament in RRAM
US9012307B2 (en) * 2010-07-13 2015-04-21 Crossbar, Inc. Two terminal resistive switching device structure and method of fabricating
US8473075B2 (en) 2010-06-25 2013-06-25 Advanced Bionics Cochlear implant system with removable stylet
US8884261B2 (en) 2010-08-23 2014-11-11 Crossbar, Inc. Device switching using layered device structure
US9155861B2 (en) 2010-09-20 2015-10-13 Neuronexus Technologies, Inc. Neural drug delivery system with fluidic threads
WO2011029960A2 (en) 2011-01-04 2011-03-17 Advanced Bionics Ag Hearing instrument for round window stimulation
CN103503484B (zh) 2011-03-23 2017-07-21 耳蜗有限公司 听力设备的调配
US20120245534A1 (en) * 2011-03-25 2012-09-27 Med-El Elektromedizinische Geraete Gmbh Drug Delivery Electrode with Temporary Fill Tube
US20130190839A1 (en) 2012-01-20 2013-07-25 Jane Rapsey Drug delivery using a sacrificial host
US9685608B2 (en) 2012-04-13 2017-06-20 Crossbar, Inc. Reduced diffusion in metal electrode for two-terminal memory
US9741765B1 (en) 2012-08-14 2017-08-22 Crossbar, Inc. Monolithically integrated resistive memory using integrated-circuit foundry compatible processes
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
KR102390107B1 (ko) 2013-05-30 2022-04-25 그라함 에이치. 크리시 국부 신경 자극
US9333338B2 (en) * 2013-10-15 2016-05-10 Med-El Elektromedizinische Geraete Gmbh Electrode for common cavity cochlear malformation
US10290801B2 (en) 2014-02-07 2019-05-14 Crossbar, Inc. Scalable silicon based resistive memory device
US9616207B2 (en) * 2014-06-26 2017-04-11 Cochlear Limited Treatment of the ear
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
US11642453B2 (en) 2017-01-10 2023-05-09 A.T. Still University Fluid infusion system
WO2019058330A1 (en) * 2017-09-22 2019-03-28 Cochlear Limited IMPLANTATIONS OF FLUID FLOW THROUGH THE MIDDLE EAR AND THE INTERNAL EAR
EP3694579A4 (de) * 2017-10-12 2021-07-07 Cochlear Limited Klinisch-basierte automatisierte abgabe von behandlungssubstanzen an das innenohr
EP3706856A4 (de) 2017-11-07 2021-08-18 Neurostim Oab, Inc. Nicht-invasiver nervenaktivator mit adaptiver schaltung
KR102121497B1 (ko) * 2018-03-16 2020-06-10 의료법인 성광의료재단 고실 내 전류 인가 장치 및 이를 이용한 고실 내 전류 인가 방법
WO2019180614A1 (en) * 2018-03-20 2019-09-26 Cochlear Limited Prosthesis management of body physiology
CN112702983B (zh) 2018-04-19 2023-06-30 斯皮拉尔诊疗有限公司 内耳药物递送装置和使用方法
CN112469466A (zh) * 2018-08-24 2021-03-09 科利耳有限公司 哺乳动物内部的质量输送
CN114126704A (zh) 2019-06-26 2022-03-01 神经科学技术有限责任公司 具有自适应电路的非侵入性神经激活器
US11890438B1 (en) * 2019-09-12 2024-02-06 Cochlear Limited Therapeutic substance delivery
JP2023506713A (ja) 2019-12-16 2023-02-20 ニューロスティム テクノロジーズ エルエルシー 昇圧電荷送達を用いた非侵襲性神経アクティベータ
WO2023026240A1 (en) * 2021-08-26 2023-03-02 Cochlear Limited Inner ear access determination

Family Cites Families (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US3890977A (en) * 1974-03-01 1975-06-24 Bruce C Wilson Kinetic memory electrodes, catheters and cannulae
US4046151A (en) * 1976-04-30 1977-09-06 Medtronic, Inc. Body implantable lead with stiffening stylet
US4154247A (en) * 1977-04-01 1979-05-15 Medtronic, Inc. Formable cardiac pacer lead and method of assembly and attachment to a body organ
DK141034B (da) 1977-11-22 1979-12-31 C C Hansen Elektrode til indsaetning i oerets snegl (cochlea)
AU529974B2 (en) 1978-05-04 1983-06-30 University Of Melbourne, The Electrode for human cochlea
US4357497A (en) * 1979-09-24 1982-11-02 Hochmair Ingeborg System for enhancing auditory stimulation and the like
US4306563A (en) * 1979-11-28 1981-12-22 Firma Pfrimmer & Co. Pharmazeutische Werke Erlangen Gmbh Catheter for introduction into body cavities
US4381013A (en) * 1981-03-19 1983-04-26 Medtronic, Inc. "J" Stylet wire
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
US4532930A (en) * 1983-04-11 1985-08-06 Commonwealth Of Australia, Dept. Of Science & Technology Cochlear implant system for an auditory prosthesis
US4577642A (en) * 1985-02-27 1986-03-25 Medtronic, Inc. Drug dispensing body implantable lead employing molecular sieves and methods of fabrication
CA1240784A (en) * 1985-08-30 1988-08-16 Patrick D. Van Der Puije Cochlea implant
US4844099A (en) * 1986-11-24 1989-07-04 Telectronics, N.V. Porous pacemaker electrode tip using a porous substrate
US4784161A (en) * 1986-11-24 1988-11-15 Telectronics, N.V. Porous pacemaker electrode tip using a porous substrate
US4819662A (en) * 1987-10-26 1989-04-11 Cardiac Pacemakers, Inc. Cardiac electrode with drug delivery capabilities
US5052407A (en) 1988-04-14 1991-10-01 Mieczyslaw Mirowski Cardiac defibrillation/cardioversion spiral patch electrode
GB8815968D0 (en) 1988-07-05 1988-08-10 Pfizer Ltd Veterinary devices
US4994069A (en) * 1988-11-02 1991-02-19 Target Therapeutics Vaso-occlusion coil and method
US5458631A (en) * 1989-01-06 1995-10-17 Xavier; Ravi Implantable catheter with electrical pulse nerve stimulators and drug delivery system
EP0412191B1 (de) * 1989-08-09 1993-02-03 Siemens Aktiengesellschaft Implantierbarer Injektionskörper
US4972848A (en) * 1989-08-23 1990-11-27 Medtronic, Inc. Medical electrical lead with polymeric monolithic controlled release device and method of manufacture
US5092332A (en) * 1990-02-22 1992-03-03 Medtronic, Inc. Steroid eluting cuff electrode for peripheral nerve stimulation
US5265608A (en) * 1990-02-22 1993-11-30 Medtronic, Inc. Steroid eluting electrode for peripheral nerve stimulation
US5077352A (en) * 1990-04-23 1991-12-31 C. R. Bard, Inc. Flexible lubricious organic coatings
US5120322A (en) * 1990-06-13 1992-06-09 Lathrotec, Inc. Method and apparatus for treatment of fibrotic lesions
FI88467C (fi) * 1991-04-25 1993-05-25 Reijo Sakari Mustonen Anordning foer skaerbraenning under vattnet
US5447533A (en) * 1992-09-03 1995-09-05 Pacesetter, Inc. Implantable stimulation lead having an advanceable therapeutic drug delivery system
US5496362A (en) * 1992-11-24 1996-03-05 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
JPH06205842A (ja) 1992-12-04 1994-07-26 Siemens Ag 植え込み可能な医療装置用リードアッセンブリ
US5474542A (en) * 1993-10-01 1995-12-12 Gandi; Robert A. Catheter having imperforate protective barrier and method for making and using the same
CA2132783C (en) * 1993-10-18 2001-12-25 Leonard Pinchuk Lubricious silicone surface modification
US5531781A (en) 1993-11-02 1996-07-02 Alferness; Clifton A. Implantable lead having a steering distal guide tip
US6129685A (en) * 1994-02-09 2000-10-10 The University Of Iowa Research Foundation Stereotactic hypothalamic obesity probe
US8795242B2 (en) * 1994-05-13 2014-08-05 Kensey Nash Corporation Resorbable polymeric device for localized drug delivery
US5562723A (en) 1994-10-06 1996-10-08 Medtronic, Inc. Medical electrical lead having a reinforced tine assembly
US5554114A (en) * 1994-10-20 1996-09-10 Micro Therapeutics, Inc. Infusion device with preformed shape
US5628778A (en) 1994-11-21 1997-05-13 Medtronic Inc. Single pass medical electrical lead
US5645585A (en) * 1996-03-15 1997-07-08 Cochlear Ltd. Cochlear electrode implant assembly with positioning system therefor
JPH10506560A (ja) * 1995-04-19 1998-06-30 シュナイダー(ユーエスエー)インク 薬品を放出する被覆されたステント
US5628774A (en) 1995-04-27 1997-05-13 Incontrol, Inc. Cardiac lead with composite insulating structure
US5800500A (en) * 1995-08-18 1998-09-01 Pi Medical Corporation Cochlear implant with shape memory material and method for implanting the same
JP3576563B2 (ja) 1995-09-20 2004-10-13 コックレア リミティド 蝸牛及び他の器官の移植装置における生体再吸収性ポリマーの用途
AU702746B2 (en) * 1995-09-20 1999-03-04 Cochlear Limited Bioresorbable polymer use in cochlear and other implants
SE9601541D0 (sv) 1995-11-08 1996-04-23 Pacesetter Ab Styrtrådsenhet
EP0861570B1 (de) * 1995-11-13 2005-08-10 Cochlear Limited Implantierbares mikrofon für cochleare implantate
SE9504334D0 (sv) 1995-12-04 1995-12-04 Pacesetter Ab Styrtrådsenhet
SE9504333D0 (sv) 1995-12-04 1995-12-04 Pacesetter Ab Styrtrådsenhet
SE9504678D0 (sv) 1995-12-28 1995-12-28 Pacesetter Ab Elektrodkabel
SE9504676D0 (sv) 1995-12-28 1995-12-28 Pacesetter Ab Elektrodkabel
SE9504675D0 (sv) 1995-12-28 1995-12-28 Pacesetter Ab Implanterbar elektrodkabelanordning med flera elektrodkontaktelement
SE9504677D0 (sv) 1995-12-28 1995-12-28 Pacesetter Ab Elektrodkabel
US5929041A (en) * 1996-02-23 1999-07-27 Amgen Inc. Method for preventing and treating sensorineural hearing loss and vestibular disorders using glial cell line-derived neurotrophic factor(GDNF) protein product
US5697951A (en) * 1996-04-25 1997-12-16 Medtronic, Inc. Implantable stimulation and drug infusion techniques
US6735471B2 (en) * 1996-04-30 2004-05-11 Medtronic, Inc. Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure
US5755474A (en) * 1996-12-05 1998-05-26 Illinois Tool Works Inc. Dual size cup carrier
US5755765A (en) * 1997-01-24 1998-05-26 Cardiac Pacemakers, Inc. Pacing lead having detachable positioning member
US6086582A (en) * 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
US5975085A (en) * 1997-05-01 1999-11-02 Medtronic, Inc. Method of treating schizophrenia by brain stimulation and drug infusion
US6119044A (en) * 1997-06-02 2000-09-12 Advanced Bionics Corporation Cochlear electrode array with positioning stylet
US6038484A (en) * 1997-09-02 2000-03-14 Advanced Bionics Corporation Cochlear electrode with modiolar-hugging system including a flexible positioner
US6125302A (en) * 1997-09-02 2000-09-26 Advanced Bionics Corporation Precurved modiolar-hugging cochlear electrode
US5902329A (en) * 1997-11-14 1999-05-11 Pacesetter, Inc. Explantable lead
US6070104A (en) 1997-11-28 2000-05-30 Medtronic, Inc. Medical electrical right atrium and coronary sinus lead
US5957966A (en) * 1998-02-18 1999-09-28 Intermedics Inc. Implantable cardiac lead with multiple shape memory polymer structures
US6078841A (en) * 1998-03-27 2000-06-20 Advanced Bionics Corporation Flexible positioner for use with implantable cochlear electrode array
DE69915235T2 (de) 1998-04-30 2005-04-14 Medtronic, Inc., Minneapolis Implantierbares system, das medikamente freisetzende zellen enthält, für eine bedarfsgerechte, lokale verabreichung von medikamenten
US6321125B1 (en) * 1998-08-26 2001-11-20 Advanced Bionics Corporation Cochlear electrode system including distally attached flexible positioner
US6304787B1 (en) * 1998-08-26 2001-10-16 Advanced Bionics Corporation Cochlear electrode array having current-focusing and tissue-treating features
US6163729A (en) * 1998-08-26 2000-12-19 Advanced Bionics Corporation Method of positioning an implantable cochlear electrode array within a cochlea
US6309410B1 (en) * 1998-08-26 2001-10-30 Advanced Bionics Corporation Cochlear electrode with drug delivery channel and method of making same
US6038482A (en) * 1998-10-30 2000-03-14 Pacesetter, Inc. Open bore electrode with a tiered drug therapy delivery system
US6398758B1 (en) * 1999-02-16 2002-06-04 Stephen C. Jacobsen Medicament delivery system
US6136021A (en) 1999-03-23 2000-10-24 Cardiac Pacemakers, Inc. Expandable electrode for coronary venous leads
US6298272B1 (en) 1999-03-29 2001-10-02 Cardiac Pacemakers, Inc. High impedance electrode tip with internal drug delivery capability
US6259951B1 (en) * 1999-05-14 2001-07-10 Advanced Bionics Corporation Implantable cochlear stimulator system incorporating combination electrode/transducer
AU776958B2 (en) * 1999-05-21 2004-09-30 Cochlear Limited A cochlear implant electrode array
DE10032000A1 (de) * 1999-07-01 2001-01-25 Medtronic Inc Medizinisches Gerät und Verfahren zur elektrophoretischen in situ Abgabe eines therapheutischen Wirkstoffs
SE0000285D0 (sv) 1999-12-07 2000-01-31 Mika Lahtinen Medical implant
US6850803B1 (en) 2000-06-16 2005-02-01 Medtronic, Inc. Implantable medical device with a recharging coil magnetic shield
US6572531B2 (en) * 2000-06-17 2003-06-03 Alfred E. Mann Foundation For Scientific Reseach Implantable middle ear implant
AU2001277474A1 (en) 2000-07-12 2002-01-21 Mannesmannrohren-Werke Ag Method for producing metallic, non-rotationally symmetrical rings with a constant wall thickness over their circumference
US6443891B1 (en) 2000-09-20 2002-09-03 Medtronic, Inc. Telemetry modulation protocol system for medical devices
AU777272B2 (en) * 2000-10-04 2004-10-07 Cochlear Limited Cochlear implant electrode array
CA2392996A1 (en) * 2000-10-04 2002-04-11 Cochlear Limited Combination stylet and straightening coating for a cochlear implant electrode array
DE60113293T2 (de) * 2000-10-11 2006-06-29 Cochlear Ltd., Lane Cove Cochlearimplantatelektrodenanordnung mit Doppelstilletteinführgrät
US7894916B2 (en) 2000-10-17 2011-02-22 Cochlear Limited Insertion tool for a cochlear implant electrode array
US9089450B2 (en) * 2000-11-14 2015-07-28 Cochlear Limited Implantatable component having an accessible lumen and a drug release capsule for introduction into same
AUPR148400A0 (en) * 2000-11-14 2000-12-07 Cochlear Limited Apparatus for delivery of pharmaceuticals to the cochlea
ATE518500T1 (de) * 2000-11-29 2011-08-15 Cochlear Ltd Vorgeformtes implantat mit einer reihe von elektroden zur anwendung in der gehörschnecke
CA2436814A1 (en) 2000-12-01 2002-07-18 Nephros Therapeutics, Inc. Intravascular drug delivery device and use therefor
US6567704B2 (en) * 2000-12-20 2003-05-20 Medtronic, Inc. Medical electrical lead and method of use
AUPR364601A0 (en) * 2001-03-12 2001-04-12 Cochlear Limited Curved cochlear implant electrode array
SE0101340D0 (sv) 2001-04-12 2001-04-12 St Jude Medical An electrically conductive lead and a method of producing such a lead
AU2002305313A1 (en) 2001-04-30 2002-11-11 Medtronic, Inc. Implantable medical device and patch system
AU2002363103B2 (en) * 2001-10-24 2008-10-16 Med-El Elektromedizinische Gerate Ges.M.B.H. Implantable fluid delivery apparatuses and implantable electrode
US20070088335A1 (en) * 2001-10-24 2007-04-19 Med-El Elektromedizinische Geraete Gmbh Implantable neuro-stimulation electrode with fluid reservoir
US6936040B2 (en) * 2001-10-29 2005-08-30 Medtronic, Inc. Method and apparatus for endovenous pacing lead
WO2003049658A1 (en) 2001-12-10 2003-06-19 Hearworks Pty. Ltd. Control of shape of an implantable electrode array
AUPS081502A0 (en) * 2002-02-28 2002-03-21 Cochlear Limited Connector for drug delivery system
US7206639B2 (en) * 2002-03-15 2007-04-17 Sarcos Investments Lc Cochlear drug delivery system and method
AT507045B1 (de) * 2002-11-29 2010-04-15 Cochlear Ltd Implantierbare, gewebe-stimulierende vorrichtung
US20070184085A1 (en) * 2006-02-03 2007-08-09 Boston Scientific Scimed, Inc. Ultrasound activated medical device
DE102006012231A1 (de) 2006-03-16 2007-09-20 Schaltbau Gmbh Stromtrennvorrichtung
US8133215B2 (en) * 2007-08-13 2012-03-13 Cochlear Limited Independently-manufactured drug delivery module and corresponding receptacle in an implantable medical device
US8271101B2 (en) * 2007-08-29 2012-09-18 Advanced Bionics Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead
WO2009029866A2 (en) * 2007-08-29 2009-03-05 Advanced Bionics, Llc Minimizing trauma during and after insertion of a cochlear lead
EP2265529A4 (de) 2008-03-31 2013-01-02 Saint Gobain Abrasives Inc Kfz-abdeckband und spender
CN102186528B (zh) 2008-10-15 2013-08-07 Med-El电气医疗器械有限公司 内耳给药装置

Also Published As

Publication number Publication date
EP1340408A4 (de) 2005-07-13
US20040078057A1 (en) 2004-04-22
US20090292329A1 (en) 2009-11-26
AU2002223270A1 (en) 2002-05-27
US8401674B2 (en) 2013-03-19
EP1340408B1 (de) 2008-10-22
US7571012B2 (en) 2009-08-04
US9623221B2 (en) 2017-04-18
US20160136400A1 (en) 2016-05-19
JP4065775B2 (ja) 2008-03-26
CA2428542A1 (en) 2002-05-23
JP2004525663A (ja) 2004-08-26
EP1340408A1 (de) 2003-09-03
US20140155811A1 (en) 2014-06-05
AUPR148400A0 (en) 2000-12-07
WO2002041666A1 (en) 2002-05-23
US20120046702A1 (en) 2012-02-23
ATE411833T1 (de) 2008-11-15

Similar Documents

Publication Publication Date Title
DE60136293D1 (de) Vorrichtung zum abliefern von pharmazeutika an das innenohr
ATE315420T1 (de) Elektrodenleitung zur stimulation von wirbelsaülen
WO2006105463A3 (en) Monopolar stimulation assembly including at least one remote electrode
DE60110980D1 (de) Katheterleitung zur Implantation in den intrathekalen Raum
ATE531349T1 (de) Einführvorrichtung für eine elektrodenanordnung
WO2006010837A3 (fr) Dispositif our le transfert de molecules aux cellules utilisant une force electrique
ATE263516T1 (de) Elektrodenanordnung zur elektrothermischen behandlung des menschlichen oder tierischen körpers
DE602006019309D1 (de) Herzstimulationssystem
BR0213245A (pt) Dispositivo e sonda para a aplicação ocular de um princìpio ativo
ATE372806T1 (de) Herzschrittmacher
AU1668702A (en) Electro-acupuncture device with stimulation electrode assembly
ITFI970071A0 (it) Sistema per la defibrillazione elettrica cardiaca impiantabile con attenuazione del dolore derivante dallo shock elettrico mediante stimolazione meurale.
DE69332856D1 (de) Haarnadelförmiges ribozym
ATE192663T1 (de) Tragbares iontophoresis system
DE60131775D1 (de) Eine implantierbare oder einführbare vorrichtung zur abgabe therapeutischer mittel
DE60042252D1 (de) Implantierbare medizinische Vorrichtung
DE50007627D1 (de) Vorrichtung zur erfassung elektrischer potentiale im stirnbereich eines patienten
DE60327090D1 (de) Implantierbare medizinische vorrichtung
ES2213707T3 (es) Estimulacion del crecimiento oseo con un derivado peptidico de la trombina.
DK1750596T3 (da) Forbindelseselement, der kan indføres i en menneske- eller dyrekrops knoglestruktur, og tilhørende lokaliseringssystem
ATE323395T1 (de) Elektrodenfeld mit uneinheitlichem elektrodenabstand
DE60216970D1 (de) Implantierbare herzstimulationsvorrichtung sowie diese vorrichtung enthaltendes system
AU2003246537A1 (en) Device for needle-free injection of a medium into the tissue of a human or an animal, device for needle free production of an injection channel and method for the needle free injection of a medium in the tissue
WO2001003604A3 (en) Electrode design and stimulator for antler-bearing animals
EP1295611A4 (de) Verbindungen für den transfer von oligonukleotiden(03.01.02)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: GRUENECKER, KINKELDEY, STOCKMAIR & SCHWANHAEUSSER,