DE60140898D1 - Synthetische nukleinsäuremolekül-zusammensetzungen und verfahren zu ihrer herstellung - Google Patents
Synthetische nukleinsäuremolekül-zusammensetzungen und verfahren zu ihrer herstellungInfo
- Publication number
- DE60140898D1 DE60140898D1 DE60140898T DE60140898T DE60140898D1 DE 60140898 D1 DE60140898 D1 DE 60140898D1 DE 60140898 T DE60140898 T DE 60140898T DE 60140898 T DE60140898 T DE 60140898T DE 60140898 D1 DE60140898 D1 DE 60140898D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- synthetic nucleic
- production
- acid molecule
- molecule compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/645,706 US7879540B1 (en) | 2000-08-24 | 2000-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
PCT/US2001/026566 WO2002016944A2 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60140898D1 true DE60140898D1 (de) | 2010-02-04 |
Family
ID=24590123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60140898T Expired - Lifetime DE60140898D1 (de) | 2000-08-24 | 2001-08-24 | Synthetische nukleinsäuremolekül-zusammensetzungen und verfahren zu ihrer herstellung |
Country Status (10)
Country | Link |
---|---|
US (3) | US7879540B1 (de) |
EP (1) | EP1341808B1 (de) |
JP (3) | JP2004520807A (de) |
AT (1) | ATE452905T1 (de) |
AU (2) | AU2001285278B2 (de) |
CA (1) | CA2420328A1 (de) |
DE (1) | DE60140898D1 (de) |
DK (1) | DK1341808T3 (de) |
ES (1) | ES2335268T3 (de) |
WO (1) | WO2002016944A2 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6602677B1 (en) * | 1997-09-19 | 2003-08-05 | Promega Corporation | Thermostable luciferases and methods of production |
US20030157643A1 (en) * | 2000-08-24 | 2003-08-21 | Almond Brian D | Synthetic nucleic acids from aquatic species |
US7879540B1 (en) | 2000-08-24 | 2011-02-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
US7413874B2 (en) | 2002-12-09 | 2008-08-19 | University Of Miami | Nucleic acid encoding fluorescent proteins from aquatic species |
DE602004030104D1 (de) * | 2003-05-06 | 2010-12-30 | Nat Inst Of Advanced Ind Scien | System zur bestimmung der aktivität mehrerer gentranskriptionen |
KR20060065693A (ko) * | 2003-08-29 | 2006-06-14 | 다카라 바이오 가부시키가이샤 | 기능적 뉴클레오티드 분자 검출 방법 |
EP2298902B1 (de) | 2003-10-10 | 2015-04-22 | Promega Corporation | Luciferase-Biosensor |
US7728118B2 (en) | 2004-09-17 | 2010-06-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
EP1799823B9 (de) * | 2004-09-17 | 2010-09-15 | Institut Pasteur | Verfahren zur modulation der entwicklung eines durch eine nukleinsäuresequenz kodierten polypeptids |
US7939649B2 (en) * | 2005-09-06 | 2011-05-10 | Stanford University | Polynucleotide encoding luciferase |
US8383797B2 (en) | 2005-11-16 | 2013-02-26 | Toyo Boseki Kabushiki Kaisha | Luciferase gene optimized for use in imaging of intracellular luminescence |
EP2004813B1 (de) | 2006-04-03 | 2015-06-03 | Promega Corporation | Permutierte und nichtpermutierte Luciferase-biosensoren, die zyklische Nukleotiden binden |
JP5409354B2 (ja) * | 2006-05-25 | 2014-02-05 | インスティチュート フォー アドバンスド スタディ | 配列モチーフを同定するための方法、およびその応用 |
JP6199533B2 (ja) | 2006-07-13 | 2017-09-20 | インスティチュート フォー アドバンスド スタディ | ウイルス阻害性ヌクレオチド配列およびワクチン |
JP5680302B2 (ja) | 2006-10-30 | 2015-03-04 | プロメガ コーポレイションPromega Corporation | キネティクス及び機能発現が高められた突然変異形ヒドロラーゼ・タンパク質 |
BRPI0813963A2 (pt) | 2007-06-29 | 2015-01-06 | Hoffmann La Roche | Mutante de cadeia pesada que leva a uma melhor produção de imunoglobulina |
JP5258084B2 (ja) * | 2008-01-07 | 2013-08-07 | 株式会社ProbeX | タンパク質間相互作用の検出方法 |
WO2009142735A2 (en) | 2008-05-19 | 2009-11-26 | Promega Corporation | LUCIFERASE BIOSENSORS FOR cAMP |
JP4849698B2 (ja) | 2009-05-29 | 2012-01-11 | 国立大学法人 東京大学 | タンパク質間相互作用の高感度検出方法 |
US9290794B2 (en) | 2010-05-11 | 2016-03-22 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
EP2990479B1 (de) | 2010-05-11 | 2019-03-27 | Promega Corporation | Mutante protease-biosensoren mit verbesserten erkennungseigenschaften |
EP2580329B1 (de) * | 2010-06-10 | 2018-07-11 | Active Motif, Inc. | Modifizierte renilla-luciferase-nukleinsäuren und verfahren zu ihrer verwendung |
ES2543913T3 (es) | 2010-11-02 | 2015-08-25 | Promega Corporation | Derivados de coelenterazina y métodos de uso de los mismos |
WO2012061530A2 (en) | 2010-11-02 | 2012-05-10 | Promega Corporation | Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use |
WO2012174271A2 (en) | 2011-06-16 | 2012-12-20 | The Regents Of The University Of California | Synthetic gene clusters |
EP3467119B1 (de) | 2011-11-11 | 2022-02-23 | Promega Corporation | Mutante prothease-biosensoren mit verbesserten erkennungseigenschaften |
EP2841572B1 (de) | 2012-04-27 | 2019-06-19 | Duke University | Genetische korrektur mutierter gene |
US10968446B2 (en) | 2012-11-01 | 2021-04-06 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
WO2014151282A1 (en) | 2013-03-15 | 2014-09-25 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
JP6588917B2 (ja) | 2014-01-29 | 2019-10-09 | プロメガ コーポレイションPromega Corporation | 生細胞への適用のためのプロ基質 |
EP3099683B1 (de) | 2014-01-29 | 2020-08-05 | Promega Corporation | Chinonmaskierte sonden als markierungsreagenzien für zellaufnahmemessungen |
JP6811173B2 (ja) * | 2014-09-11 | 2021-01-13 | プロメガ コーポレイションPromega Corporation | 増強された発光を産生するために赤外発光基質を活用するルシフェラーゼ配列 |
CN115418357A (zh) | 2015-07-13 | 2022-12-02 | 皮沃特生物公司 | 改良植物性状的方法及组合物 |
WO2017062412A1 (en) | 2015-10-05 | 2017-04-13 | Massachusetts Institute Of Technology | Nitrogen fixation using refactored nif clusters |
EP4089175A1 (de) | 2015-10-13 | 2022-11-16 | Duke University | Genom-engineering mit typ-i-crispr-systemen in eukaryotischen zellen |
JP6978492B2 (ja) | 2016-09-09 | 2021-12-08 | プロメガ コーポレイションPromega Corporation | 二重保護されたプロセレンテラジン基質 |
MX2019008285A (es) | 2017-01-12 | 2019-11-11 | Pivot Bio Inc | Métodos y composiciones para mejorar atributos de plantas. |
US11579149B2 (en) | 2017-11-01 | 2023-02-14 | Queen's University At Kingston | Hippo pathway bioluminescent biosensor |
CN112739668A (zh) | 2018-06-27 | 2021-04-30 | 皮沃特生物股份有限公司 | 包括重构固氮微生物的农业组合物 |
EP3914734B1 (de) | 2019-01-25 | 2024-03-13 | President and Fellows of Harvard College | Zusammensetzungen und verfahren zur sequenzierung von nukleinsäuren |
KR20220024954A (ko) | 2019-06-28 | 2022-03-03 | 에프. 호프만-라 로슈 아게 | 항체의 생성 방법 |
AU2020400056A1 (en) | 2019-12-12 | 2022-07-07 | President And Fellows Of Harvard College | Compositions and methods for light-directed biomolecular barcoding |
AU2021261343A1 (en) | 2020-04-22 | 2022-11-03 | President And Fellows Of Harvard College | Isothermal methods, compositions, kits, and systems for detecting nucleic acids |
WO2023215505A1 (en) | 2022-05-04 | 2023-11-09 | Promega Corporation | Modified dehalogenase with extended surface loop regions |
WO2023215452A2 (en) | 2022-05-04 | 2023-11-09 | Promega Corporation | Split modified dehalogenase variants |
US20240060059A1 (en) | 2022-05-04 | 2024-02-22 | Promega Corporation | Circularly permuted dehalogenase variants |
Family Cites Families (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE428379B (sv) | 1978-05-31 | 1983-06-27 | Lkb Produkter Ab | Bioluminiscens bestemning av atp och reagens herfor |
US4412001A (en) | 1981-01-30 | 1983-10-25 | Board Of Trustees Of The University Of Illinois | Isolation of bacterial luciferase |
US4503142A (en) | 1982-06-25 | 1985-03-05 | Litton Bionetics, Inc. | Open reading frame vectors |
US4581335A (en) | 1982-12-01 | 1986-04-08 | Texas A&M University System | Process for producing a cloned luciferase-synthesizing microorganism |
US5096825A (en) | 1983-01-12 | 1992-03-17 | Chiron Corporation | Gene for human epidermal growth factor and synthesis and expression thereof |
US5380831A (en) | 1986-04-04 | 1995-01-10 | Mycogen Plant Science, Inc. | Synthetic insecticidal crystal protein gene |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US5583024A (en) | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
US5221623A (en) | 1986-07-22 | 1993-06-22 | Boyce Thompson Institute For Plant Research, Inc. | Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms |
US4968613A (en) | 1987-07-29 | 1990-11-06 | Kikkoman Corporation | Luciferase gene and novel recombinant DNA as well as a method of producing luciferase |
US5182202A (en) | 1987-11-30 | 1993-01-26 | Kikkoman Corporation | Purified luciferase from luciola cruciata |
JPH088864B2 (ja) | 1988-04-12 | 1996-01-31 | キッコーマン株式会社 | ルシフェラーゼ |
EP0353464B1 (de) | 1988-07-01 | 1993-10-20 | Kikkoman Corporation | Luciferase-Gen und neue rekombinante DNA sowie Verfahren zur Herstellung von Luciferase |
WO1990001542A1 (en) | 1988-08-09 | 1990-02-22 | Toray Industries, Inc. | Luciferase, luciferase-coding gene, and process for preparing luciferase |
US5604123A (en) | 1988-08-09 | 1997-02-18 | Toray Industries, Inc. | Luciferase, gene encoding the same and production process of the same |
JPH0771485B2 (ja) | 1988-09-01 | 1995-08-02 | キッコーマン株式会社 | ルシフェラーゼの製造法 |
US5196524A (en) | 1989-01-06 | 1993-03-23 | Eli Lilly And Company | Fusion reporter gene for bacterial luciferase |
CA2009925C (en) | 1989-02-14 | 2002-10-01 | Koichi Kondo | Method for enhancement of chemiluminescence |
FI901681A0 (fi) | 1989-04-10 | 1990-04-03 | Ela Technologies Inc | Foerfarande foer oekning av kaensligheten hos luminescensanalyser. |
JPH03167288A (ja) | 1989-11-27 | 1991-07-19 | Chisso Corp | 界面活性剤によるエクオリンの増感発光法 |
US5292658A (en) | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
US5219737A (en) | 1990-03-27 | 1993-06-15 | Kikkoman Corporation | Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase |
WO1991016432A1 (en) | 1990-04-18 | 1991-10-31 | Plant Genetic Systems N.V. | Modified bacillus thuringiensis insecticidal-crystal protein genes and their expression in plant cells |
US5283179A (en) | 1990-09-10 | 1994-02-01 | Promega Corporation | Luciferase assay method |
CA2105984C (en) | 1991-03-11 | 2002-11-26 | Milton J. Cormier | Cloning and expression of renilla luciferase |
US5229285A (en) | 1991-06-27 | 1993-07-20 | Kikkoman Corporation | Thermostable luciferase of firefly, thermostable luciferase gene of firefly, novel recombinant dna, and process for the preparation of thermostable luciferase of firefly |
CA2122261A1 (en) * | 1991-10-30 | 1993-05-13 | Marc Cornelissen | Modified genes and their expression in plant cells |
US5629168A (en) | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
AT401526B (de) | 1993-02-10 | 1996-09-25 | Scheirer Winfried | Reagenzlösung zur stabilisierung der lumineszenz bei der luciferasemessung |
CA2104815A1 (en) | 1993-02-26 | 1994-08-27 | Naotaka Kuroda | Method for measuring adenyl group-containing substances |
US5610335A (en) | 1993-05-26 | 1997-03-11 | Cornell Research Foundation | Microelectromechanical lateral accelerometer |
US6118047A (en) | 1993-08-25 | 2000-09-12 | Dekalb Genetic Corporation | Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction |
JPH0767696A (ja) | 1993-09-06 | 1995-03-14 | Tosoh Corp | バックグランド発光の低減法 |
WO1995018853A1 (en) | 1994-01-03 | 1995-07-13 | Promega Corporation | Mutant luciferases |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
GB9501170D0 (en) | 1994-03-23 | 1995-03-08 | Secr Defence | Luciferases |
US5786464C1 (en) | 1994-09-19 | 2012-04-24 | Gen Hospital Corp | Overexpression of mammalian and viral proteins |
US5795737A (en) | 1994-09-19 | 1998-08-18 | The General Hospital Corporation | High level expression of proteins |
US5670356A (en) | 1994-12-12 | 1997-09-23 | Promega Corporation | Modified luciferase |
US6171808B1 (en) | 1995-01-20 | 2001-01-09 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Mutant luciferases |
US5744320A (en) | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
EP0859841B1 (de) | 1995-08-18 | 2002-06-19 | MorphoSys AG | Protein-/(poly)peptidbibliotheken |
US5874304A (en) | 1996-01-18 | 1999-02-23 | University Of Florida Research Foundation, Inc. | Humanized green fluorescent protein genes and methods |
US6020192A (en) | 1996-01-18 | 2000-02-01 | University Of Florida | Humanized green fluorescent protein genes and methods |
JPH09294600A (ja) | 1996-04-26 | 1997-11-18 | Kikkoman Corp | 複数のプロモーター活性の測定法 |
EP1009763A4 (de) * | 1996-06-11 | 2002-08-07 | Merck & Co Inc | Synthetische hepatitis-c gene |
JPH1087621A (ja) | 1996-09-13 | 1998-04-07 | Sankyo Co Ltd | ルシゲニン化学発光の増強剤 |
US6114148C1 (en) | 1996-09-20 | 2012-05-01 | Gen Hospital Corp | High level expression of proteins |
WO1998013487A1 (en) | 1996-09-27 | 1998-04-02 | Maxygen, Inc. | Methods for optimization of gene therapy by recursive sequence shuffling and selection |
US5976796A (en) | 1996-10-04 | 1999-11-02 | Loma Linda University | Construction and expression of renilla luciferase and green fluorescent protein fusion genes |
JP3167288B2 (ja) | 1997-03-17 | 2001-05-21 | 株式会社バンダイ | 携帯用電子機器装置 |
GB9707486D0 (en) | 1997-04-11 | 1997-05-28 | Secr Defence | Enzyme assays |
US6074859A (en) | 1997-07-08 | 2000-06-13 | Kikkoman Corporation | Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein |
US6169232B1 (en) * | 1997-07-15 | 2001-01-02 | Dow Agrosciences Llc | Nucleotide sequences of genes encoding sink protein and uses thereof for improving the nutritional quality of feeds |
AU754312C (en) | 1997-09-19 | 2005-11-10 | Promega Corporation | Thermostable luciferases and methods of production |
US6602677B1 (en) | 1997-09-19 | 2003-08-05 | Promega Corporation | Thermostable luciferases and methods of production |
US6306600B1 (en) | 1998-04-17 | 2001-10-23 | Clontech Laboratories, Inc. | Rapidly degrading GFP-fusion proteins and methods of use |
US6130313A (en) | 1997-10-02 | 2000-10-10 | Clontech Laboratories, Inc. | Rapidly degrading GFP-fusion proteins |
US7090976B2 (en) | 1999-11-10 | 2006-08-15 | Rigel Pharmaceuticals, Inc. | Methods and compositions comprising Renilla GFP |
US6700038B1 (en) | 1999-03-31 | 2004-03-02 | Wisconsin Alumni Research Foundation | Plant expression vectors based on the flock house virus genome |
JP2003510072A (ja) | 1999-09-30 | 2003-03-18 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 遺伝子発現を改変するための組成物および方法 |
EP2308974A3 (de) | 1999-10-14 | 2011-08-10 | Clontech Laboratories Inc. | Aus Anthozoa abgeleitete Chrom-/Fluorproteine sowie Verwendungsverfahren dafür |
FR2812883B1 (fr) | 2000-08-11 | 2002-10-18 | Aventis Cropscience Sa | Utilisation d'inhibiteurs d'hppd comme agents de selection dans la transformation de plantes |
US7879540B1 (en) | 2000-08-24 | 2011-02-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
US20030157643A1 (en) | 2000-08-24 | 2003-08-21 | Almond Brian D | Synthetic nucleic acids from aquatic species |
WO2002094992A2 (en) | 2001-05-18 | 2002-11-28 | Rigel Pharmaceuticals, Incorporated | Directed evolution of protein in mammalian cells |
WO2003042401A2 (en) | 2001-11-13 | 2003-05-22 | Clontech Laboratories, Inc. | Novel chromophores/fluorophores and methods for using the same |
US20040146987A1 (en) | 2002-09-16 | 2004-07-29 | Promega Corporation | Rapidly degraded reporter fusion proteins |
AU2003301883A1 (en) | 2002-10-30 | 2004-06-07 | University Of Tennessee Research Foundation | Modified luciferase nucleic acids and methods of use |
JP4311003B2 (ja) | 2002-12-02 | 2009-08-12 | アイシン精機株式会社 | 原核生物の遺伝子発現解析方法 |
US6878531B1 (en) | 2003-11-10 | 2005-04-12 | Medical College Of Georgia Research Institute | Method for multiple site-directed mutagenesis |
US7728118B2 (en) | 2004-09-17 | 2010-06-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
-
2000
- 2000-08-24 US US09/645,706 patent/US7879540B1/en not_active Expired - Fee Related
-
2001
- 2001-08-24 JP JP2002521985A patent/JP2004520807A/ja active Pending
- 2001-08-24 AU AU2001285278A patent/AU2001285278B2/en not_active Ceased
- 2001-08-24 AU AU8527801A patent/AU8527801A/xx active Pending
- 2001-08-24 DE DE60140898T patent/DE60140898D1/de not_active Expired - Lifetime
- 2001-08-24 CA CA002420328A patent/CA2420328A1/en not_active Abandoned
- 2001-08-24 EP EP01964425A patent/EP1341808B1/de not_active Expired - Lifetime
- 2001-08-24 AT AT01964425T patent/ATE452905T1/de not_active IP Right Cessation
- 2001-08-24 WO PCT/US2001/026566 patent/WO2002016944A2/en active Application Filing
- 2001-08-24 ES ES01964425T patent/ES2335268T3/es not_active Expired - Lifetime
- 2001-08-24 DK DK01964425.1T patent/DK1341808T3/da active
-
2005
- 2005-12-22 US US11/316,042 patent/US20060127988A1/en not_active Abandoned
-
2006
- 2006-10-23 JP JP2006288147A patent/JP2007006910A/ja active Pending
-
2007
- 2007-04-12 US US11/786,785 patent/US7906282B2/en not_active Expired - Fee Related
-
2010
- 2010-01-18 JP JP2010008451A patent/JP2010081942A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US7879540B1 (en) | 2011-02-01 |
WO2002016944A2 (en) | 2002-02-28 |
ATE452905T1 (de) | 2010-01-15 |
JP2007006910A (ja) | 2007-01-18 |
EP1341808A2 (de) | 2003-09-10 |
ES2335268T3 (es) | 2010-03-24 |
AU8527801A (en) | 2002-03-04 |
EP1341808B1 (de) | 2009-12-23 |
AU2001285278B2 (en) | 2008-05-08 |
US20080090291A1 (en) | 2008-04-17 |
US7906282B2 (en) | 2011-03-15 |
CA2420328A1 (en) | 2002-02-28 |
WO2002016944A3 (en) | 2003-06-26 |
JP2010081942A (ja) | 2010-04-15 |
DK1341808T3 (da) | 2010-04-12 |
JP2004520807A (ja) | 2004-07-15 |
US20060127988A1 (en) | 2006-06-15 |
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